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Aliases for ODF3L2 Gene

Aliases for ODF3L2 Gene

  • Outer Dense Fiber Of Sperm Tails 3 Like 2 2 3 5
  • C19orf19 3 4
  • Outer Dense Fiber Protein 3-Like Protein 2 3
  • Chromosome 19 Open Reading Frame 19 2

External Ids for ODF3L2 Gene

Previous HGNC Symbols for ODF3L2 Gene

  • C19orf19

Previous GeneCards Identifiers for ODF3L2 Gene

  • GC19M000417
  • GC19M000234

Summaries for ODF3L2 Gene

GeneCards Summary for ODF3L2 Gene

ODF3L2 (Outer Dense Fiber Of Sperm Tails 3 Like 2) is a Protein Coding gene. An important paralog of this gene is ODF3L1.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ODF3L2 Gene

Genomics for ODF3L2 Gene

Regulatory Elements for ODF3L2 Gene

Enhancers for ODF3L2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G000867 0.8 FANTOM5 4.9 -392.2 -392220 0.4 KLF1 PTBP1 AGO1 ZIC2 ZNF48 CCNT2 FOXM1 HIC1 ZFHX2 POLR2A CFD MED16 ODF3L2 ATP5D GPX4 TPGS1 CNN2 POLRMT BSG C19orf24
GH19G000569 2 FANTOM5 Ensembl ENCODE dbSUPER 1.7 -98.3 -98341 7.4 CREB3L1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 TBX21 MEF2D GLIS1 NR2C1 LOC105372233 TMEM259 MIER2 BSG POLRMT ENSG00000267317 CDC34 R3HDM4 ODF3L2 GC19P000572
GH19G000441 0.6 FANTOM5 1.6 +33.0 33032 0.3 HIC1 KLF1 ZNF366 SCRT2 NR2F2 ZBTB17 SHC2 FGF22 HCN2 PALM C2CD4C ODF3L2 PIR58364 PIR54633
GH19G000487 1.7 FANTOM5 ENCODE dbSUPER 0.4 -13.9 -13861 2.7 HDGF CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF766 ZNF207 ZNF143 KLF13 CFD SHC2 LOC105372232 MADCAM1 MIDN ODF3L2
GH19G000479 1.5 Ensembl ENCODE dbSUPER 0.4 -5.3 -5303 0.8 HDGF PKNOX1 ARNT ARID4B SIN3A YBX1 ZNF2 ZNF143 ZNF207 ZNF548 TMEM259 CFD MIER2 RPS15 CIRBP MIDN APC2 PLPPR3 ENSG00000267317 MADCAM1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ODF3L2 on UCSC Golden Path with GeneCards custom track

Genomic Location for ODF3L2 Gene

463,346 bp from pter
474,983 bp from pter
11,638 bases
Minus strand

Genomic View for ODF3L2 Gene

Genes around ODF3L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ODF3L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ODF3L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ODF3L2 Gene

Proteins for ODF3L2 Gene

  • Protein details for ODF3L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Outer dense fiber protein 3-like protein 2
    Protein Accession:
    Secondary Accessions:
    • Q3SX65
    • Q8N1L2

    Protein attributes for ODF3L2 Gene

    289 amino acids
    Molecular mass:
    30781 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ODF3L2 Gene


neXtProt entry for ODF3L2 Gene

Post-translational modifications for ODF3L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ODF3L2 Gene

No data available for DME Specific Peptides for ODF3L2 Gene

Domains & Families for ODF3L2 Gene

Protein Domains for ODF3L2 Gene


Suggested Antigen Peptide Sequences for ODF3L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ODF3 family.
  • Belongs to the ODF3 family.
genes like me logo Genes that share domains with ODF3L2: view

No data available for Gene Families for ODF3L2 Gene

Function for ODF3L2 Gene

Phenotypes for ODF3L2 Gene

genes like me logo Genes that share phenotypes with ODF3L2: view

Animal Models for ODF3L2 Gene

MGI Knock Outs for ODF3L2:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ODF3L2 Gene

Localization for ODF3L2 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ODF3L2 gene
Compartment Confidence
cytoskeleton 5
extracellular 2
nucleus 2
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for ODF3L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005881 cytoplasmic microtubule IDA 23264731
genes like me logo Genes that share ontologies with ODF3L2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ODF3L2 Gene

Pathways & Interactions for ODF3L2 Gene

SuperPathways for ODF3L2 Gene

No Data Available

Interacting Proteins for ODF3L2 Gene

Selected Interacting proteins: Q3SX64-OD3L2_HUMAN for ODF3L2 Gene via IID

Gene Ontology (GO) - Biological Process for ODF3L2 Gene


No data available for Pathways by source and SIGNOR curated interactions for ODF3L2 Gene

Drugs & Compounds for ODF3L2 Gene

No Compound Related Data Available

Transcripts for ODF3L2 Gene

mRNA/cDNA for ODF3L2 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ODF3L2 Gene

Outer dense fiber of sperm tails 3-like 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ODF3L2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1: -
SP2: - -

Relevant External Links for ODF3L2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ODF3L2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ODF3L2 Gene

mRNA differential expression in normal tissues according to GTEx for ODF3L2 Gene

This gene is overexpressed in Testis (x32.5) and Muscle - Skeletal (x7.5).

NURSA nuclear receptor signaling pathways regulating expression of ODF3L2 Gene:


SOURCE GeneReport for Unigene cluster for ODF3L2 Gene:


Evidence on tissue expression from TISSUES for ODF3L2 Gene

  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ODF3L2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ODF3L2 Gene

Orthologs for ODF3L2 Gene

This gene was present in the common ancestor of animals.

Orthologs for ODF3L2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ODF3L2 35
  • 98 (a)
(Canis familiaris)
Mammalia ODF3L2 34 35
  • 83.52 (n)
(Bos Taurus)
Mammalia ODF3L2 35
  • 81 (a)
(Rattus norvegicus)
Mammalia Odf3l2 34
  • 79.76 (n)
(Mus musculus)
Mammalia Odf3l2 34 16 35
  • 79.64 (n)
(Monodelphis domestica)
Mammalia ODF3L2 35
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia ODF3L2 35
  • 52 (a)
(Anolis carolinensis)
Reptilia ODF3L2 35
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia odf3l2 34
  • 52.73 (n)
(Danio rerio)
Actinopterygii odf3l2 35
  • 44 (a)
ODF3L2 (1 of 2) 35
  • 43 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10252 34 35
  • 44.18 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001620 34
  • 44.12 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10233 35
  • 35 (a)
Species where no ortholog for ODF3L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ODF3L2 Gene

Gene Tree for ODF3L2 (if available)
Gene Tree for ODF3L2 (if available)

Paralogs for ODF3L2 Gene

Paralogs for ODF3L2 Gene

(3) SIMAP similar genes for ODF3L2 Gene using alignment to 1 proteins: Pseudogenes for ODF3L2 Gene

genes like me logo Genes that share paralogs with ODF3L2: view

Variants for ODF3L2 Gene

Sequence variations from dbSNP and Humsavar for ODF3L2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000153545 -- 488,994(+) CACGA(A/G)CTCGG intron-variant
rs1000267324 -- 469,464(+) GCGGG(G/T)GGATC intron-variant
rs1000483064 -- 465,140(+) ATGGA(C/T)GGATG intron-variant
rs1000556166 -- 483,718(+) CAGAG(A/G)GCCAT intron-variant
rs1000572931 -- 477,954(+) CACCT(C/T)GGCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ODF3L2 Gene

Variant ID Type Subtype PubMed ID
dgv1013e212 CNV gain 25503493
dgv1672n106 CNV deletion 24896259
dgv6155n54 CNV loss 21841781
dgv6160n54 CNV gain 21841781
esv1002488 CNV deletion 20482838
esv1405790 CNV deletion 17803354
esv1453393 CNV deletion 17803354
esv1506097 CNV insertion 17803354
esv23197 CNV gain 19812545
esv2671474 CNV deletion 23128226
esv28250 CNV gain+loss 19812545
esv33417 CNV gain+loss 17666407
esv996354 CNV deletion 20482838
nsv1071881 CNV deletion 25765185
nsv1118797 CNV deletion 24896259
nsv1140344 CNV deletion 24896259
nsv1152528 CNV deletion 26484159
nsv1152852 CNV deletion 26484159
nsv138206 CNV deletion 16902084
nsv138338 CNV insertion 16902084
nsv428360 CNV gain 18775914
nsv470101 CNV loss 18288195
nsv475045 CNV novel sequence insertion 20440878
nsv477965 CNV novel sequence insertion 20440878
nsv509712 CNV insertion 20534489
nsv577978 CNV gain 21841781
nsv578100 CNV gain 21841781
nsv953938 CNV deletion 24416366
nsv954621 CNV deletion 24416366

Variation tolerance for ODF3L2 Gene

Gene Damage Index Score: 6.34; 76.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ODF3L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ODF3L2 Gene

Disorders for ODF3L2 Gene

Relevant External Links for ODF3L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ODF3L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ODF3L2 Gene

Publications for ODF3L2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. (PMID: 23264731) Fong K.W. … Chen J. (J. Cell Sci. 2013) 3 64
  5. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3 64

Products for ODF3L2 Gene

Sources for ODF3L2 Gene

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