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Aliases for ODF3L2 Gene

Aliases for ODF3L2 Gene

  • Outer Dense Fiber Of Sperm Tails 3-Like 2 2 3
  • C19orf19 3 4
  • Chromosome 19 Open Reading Frame 19 2

External Ids for ODF3L2 Gene

Previous HGNC Symbols for ODF3L2 Gene

  • C19orf19

Previous GeneCards Identifiers for ODF3L2 Gene

  • GC19M000417
  • GC19M000234

Summaries for ODF3L2 Gene

GeneCards Summary for ODF3L2 Gene

ODF3L2 (Outer Dense Fiber Of Sperm Tails 3-Like 2) is a Protein Coding gene. An important paralog of this gene is ODF3L1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ODF3L2 Gene

Genomics for ODF3L2 Gene

Regulatory Elements for ODF3L2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ODF3L2 Gene

Chromosome:
19
Start:
463,346 bp from pter
End:
474,983 bp from pter
Size:
11,638 bases
Orientation:
Minus strand

Genomic View for ODF3L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ODF3L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ODF3L2 Gene

Proteins for ODF3L2 Gene

  • Protein details for ODF3L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3SX64-OD3L2_HUMAN
    Recommended name:
    Outer dense fiber protein 3-like protein 2
    Protein Accession:
    Q3SX64
    Secondary Accessions:
    • Q3SX65
    • Q8N1L2

    Protein attributes for ODF3L2 Gene

    Size:
    289 amino acids
    Molecular mass:
    30781 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ODF3L2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ODF3L2 Gene

Proteomics data for ODF3L2 Gene at MOPED

Post-translational modifications for ODF3L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ODF3L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ODF3L2 Gene

Domains & Families for ODF3L2 Gene

Protein Domains for ODF3L2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ODF3L2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q3SX64

UniProtKB/Swiss-Prot:

OD3L2_HUMAN :
  • Belongs to the ODF3 family.
  • Contains 3 STPGR (Sperm-tail PG-rich) repeats.
Family:
  • Belongs to the ODF3 family.
Similarity:
  • Contains 3 STPGR (Sperm-tail PG-rich) repeats.
genes like me logo Genes that share domains with ODF3L2: view

No data available for Gene Families for ODF3L2 Gene

Function for ODF3L2 Gene

Phenotypes for ODF3L2 Gene

GenomeRNAi human phenotypes for ODF3L2:
genes like me logo Genes that share phenotypes with ODF3L2: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ODF3L2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ODF3L2 Gene

Localization for ODF3L2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ODF3L2 Gene COMPARTMENTS Subcellular localization image for ODF3L2 gene
Compartment Confidence
cytoskeleton 5

Gene Ontology (GO) - Cellular Components for ODF3L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005881 cytoplasmic microtubule IDA 23264731
genes like me logo Genes that share ontologies with ODF3L2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ODF3L2 Gene

Pathways & Interactions for ODF3L2 Gene

SuperPathways for ODF3L2 Gene

No Data Available

Interacting Proteins for ODF3L2 Gene

Gene Ontology (GO) - Biological Process for ODF3L2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ODF3L2 Gene

Drugs & Compounds for ODF3L2 Gene

No Compound Related Data Available

Transcripts for ODF3L2 Gene

mRNA/cDNA for ODF3L2 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ODF3L2 Gene

Outer dense fiber of sperm tails 3-like 2:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ODF3L2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ODF3L2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1: -
SP2: - -
SP3:

Relevant External Links for ODF3L2 Gene

GeneLoc Exon Structure for
ODF3L2
ECgene alternative splicing isoforms for
ODF3L2

Expression for ODF3L2 Gene

mRNA expression in normal human tissues for ODF3L2 Gene

mRNA differential expression in normal tissues according to GTEx for ODF3L2 Gene

This gene is overexpressed in Testis (x32.5) and Muscle - Skeletal (x7.5).

SOURCE GeneReport for Unigene cluster for ODF3L2 Gene Hs.104777

genes like me logo Genes that share expression patterns with ODF3L2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ODF3L2 Gene

Orthologs for ODF3L2 Gene

This gene was present in the common ancestor of animals.

Orthologs for ODF3L2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ODF3L2 35
  • 83.52 (n)
  • 79.78 (a)
ODF3L2 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Odf3l2 35
  • 79.64 (n)
  • 82.91 (a)
Odf3l2 16
Odf3l2 36
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Odf3l2 35
  • 79.76 (n)
  • 81.82 (a)
cow
(Bos Taurus)
Mammalia ODF3L2 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ODF3L2 36
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ODF3L2 36
  • 52 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ODF3L2 36
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ODF3L2 36
  • 48 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia odf3l2 35
  • 52.73 (n)
  • 43.03 (a)
zebrafish
(Danio rerio)
Actinopterygii odf3l2 36
  • 44 (a)
OneToMany
ODF3L2 (1 of 2) 36
  • 43 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001620 35
  • 44.12 (n)
  • 35.27 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10252 35
  • 44.18 (n)
  • 33.49 (a)
CG10252 36
  • 31 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10233 36
  • 35 (a)
OneToMany
Species with no ortholog for ODF3L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ODF3L2 Gene

ENSEMBL:
Gene Tree for ODF3L2 (if available)
TreeFam:
Gene Tree for ODF3L2 (if available)

Paralogs for ODF3L2 Gene

Paralogs for ODF3L2 Gene

(3) SIMAP similar genes for ODF3L2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ODF3L2: view

Variants for ODF3L2 Gene

Sequence variations from dbSNP and Humsavar for ODF3L2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1052882 -- 463,528(-) GCTTC(C/T)TGTGT utr-variant-3-prime
rs1968129 -- 463,025(+) ggccg(A/G)gctcg downstream-variant-500B
rs1968130 -- 463,326(+) GACAC(A/G)TTAAA downstream-variant-500B
rs2392794 -- 472,149(+) AGGTA(C/T)TCACC intron-variant
rs2893627 -- 471,324(+) tttgt(A/T)ttttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ODF3L2 Gene

Variant ID Type Subtype PubMed ID
nsv428360 CNV Gain 18775914
dgv3498n71 CNV Loss 21882294
nsv910083 CNV Loss 21882294
dgv3500n71 CNV Loss 21882294
dgv3504n71 CNV Loss 21882294
dgv3505n71 CNV Loss 21882294
nsv910102 CNV Loss 21882294
nsv910109 CNV Loss 21882294
nsv509712 CNV Insertion 20534489
esv2671474 CNV Deletion 23128226
nsv470101 CNV Loss 18288195
dgv3506n71 CNV Loss 21882294
dgv3507n71 CNV Loss 21882294
nsv910117 CNV Gain 21882294
nsv910119 CNV Gain 21882294
dgv3508n71 CNV Loss 21882294
dgv3509n71 CNV Loss 21882294
esv23197 CNV Gain 19812545
esv1002488 CNV Deletion 20482838
esv1405790 CNV Deletion 17803354
nsv138338 CNV Insertion 16902084
esv28250 CNV Gain+Loss 19812545
esv996354 CNV Deletion 20482838
esv1453393 CNV Deletion 17803354
nsv138206 CNV Loss 16902084
esv1506097 CNV Insertion 17803354
esv33417 CNV Gain+Loss 17666407

Variation tolerance for ODF3L2 Gene

Gene Damage Index Score: 6.34; 76.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ODF3L2 Gene

HapMap Linkage Disequilibrium report
ODF3L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ODF3L2 Gene

Disorders for ODF3L2 Gene

Relevant External Links for ODF3L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ODF3L2
genes like me logo Genes that share disorders with ODF3L2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ODF3L2 Gene

Publications for ODF3L2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 67
  4. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. (PMID: 23264731) Fong K.W. … Chen J. (J. Cell Sci. 2013) 67
  5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PMID: 20068231) Olsen J.V. … Mann M. (Sci. Signal. 2010) 67

Products for ODF3L2 Gene

Sources for ODF3L2 Gene

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