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Aliases for ODF3L1 Gene

Aliases for ODF3L1 Gene

  • Outer Dense Fiber Of Sperm Tails 3 Like 1 2 3 5

External Ids for ODF3L1 Gene

Previous GeneCards Identifiers for ODF3L1 Gene

  • GC15P073804
  • GC15P073805
  • GC15P076016
  • GC15P052772

Summaries for ODF3L1 Gene

GeneCards Summary for ODF3L1 Gene

ODF3L1 (Outer Dense Fiber Of Sperm Tails 3 Like 1) is a Protein Coding gene. An important paralog of this gene is ODF3L2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ODF3L1 Gene

Genomics for ODF3L1 Gene

Regulatory Elements for ODF3L1 Gene

Enhancers for ODF3L1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F075693 1 FANTOM5 Ensembl ENCODE 6.3 -24.9 -24944 12.0 HDGF ATF1 ARNT SIN3A GLIS2 GATA2 ZNF143 FOS NCOA1 REST LOC441728 DNM1P49 LOC105370902 ENSG00000261232 MIR631 MIR4313 MAN2C1 SNX33 ODF3L1 SCAMP5
GH15F075574 0.6 FANTOM5 2.1 -149.1 -149102 0.3 JUNB ENSG00000260274 MAN2C1 ODF3L1 C15orf39 UBE2Q2 SIN3A PTPN9 ENSG00000259931
GH15F075449 1.3 FANTOM5 ENCODE 1.1 -270.6 -270588 8.1 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 MAN2C1 ENSG00000260274 DNM1P35 DNM1P34 SNUPN LOC105370902 LOC441728 DNM1P49 EDC3 ENSG00000203392
GH15F075720 0.9 Ensembl ENCODE 0.8 -2.7 -2744 0.8 HDGF PKNOX1 GLI4 ZNF2 DEK SP3 TBX21 ZNF610 SMARCA4 GLIS1 DNM1P35 GC15P075718 ODF3L1
GH15F075722 0.5 Ensembl ENCODE 0.8 -0.2 -182 2.6 HDGF ATF1 ZNF76 KLF17 BMI1 BRCA1 RFX5 GLIS2 FOS CREM MIR4313 MIR631 ODF3L1 GC15P075718
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ODF3L1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ODF3L1 Gene

Chromosome:
15
Start:
75,723,944 bp from pter
End:
75,727,688 bp from pter
Size:
3,745 bases
Orientation:
Plus strand

Genomic View for ODF3L1 Gene

Genes around ODF3L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ODF3L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ODF3L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ODF3L1 Gene

Proteins for ODF3L1 Gene

  • Protein details for ODF3L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXM7-OD3L1_HUMAN
    Recommended name:
    Outer dense fiber protein 3-like protein 1
    Protein Accession:
    Q8IXM7

    Protein attributes for ODF3L1 Gene

    Size:
    274 amino acids
    Molecular mass:
    31065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ODF3L1 Gene

Post-translational modifications for ODF3L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ODF3L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ODF3L1 Gene

Domains & Families for ODF3L1 Gene

Protein Domains for ODF3L1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ODF3L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IXM7

UniProtKB/Swiss-Prot:

OD3L1_HUMAN :
  • Belongs to the ODF3 family.
  • Contains 2 STPGR (Sperm-tail PG-rich) repeats.
Family:
  • Belongs to the ODF3 family.
Similarity:
  • Contains 2 STPGR (Sperm-tail PG-rich) repeats.
genes like me logo Genes that share domains with ODF3L1: view

No data available for Gene Families for ODF3L1 Gene

Function for ODF3L1 Gene

Phenotypes for ODF3L1 Gene

genes like me logo Genes that share phenotypes with ODF3L1: view

Animal Model Products

miRNA for ODF3L1 Gene

miRTarBase miRNAs that target ODF3L1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ODF3L1 Gene

Localization for ODF3L1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ODF3L1 Gene COMPARTMENTS Subcellular localization image for ODF3L1 gene
Compartment Confidence
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ODF3L1 Gene

Pathways & Interactions for ODF3L1 Gene

SuperPathways for ODF3L1 Gene

No Data Available

Interacting Proteins for ODF3L1 Gene

Selected Interacting proteins: Q8IXM7-OD3L1_HUMAN for ODF3L1 Gene via IID

Symbol External ID(s) Details
CARNMT1
STAMBP

Gene Ontology (GO) - Biological Process for ODF3L1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ODF3L1 Gene

Transcripts for ODF3L1 Gene

mRNA/cDNA for ODF3L1 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ODF3L1 Gene

Outer dense fiber of sperm tails 3-like 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ODF3L1 Gene

No ASD Table

Relevant External Links for ODF3L1 Gene

GeneLoc Exon Structure for
ODF3L1
ECgene alternative splicing isoforms for
ODF3L1

Expression for ODF3L1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ODF3L1 Gene

mRNA differential expression in normal tissues according to GTEx for ODF3L1 Gene

This gene is overexpressed in Testis (x26.2).

NURSA nuclear receptor signaling pathways regulating expression of ODF3L1 Gene:

ODF3L1

SOURCE GeneReport for Unigene cluster for ODF3L1 Gene:

Hs.144348
genes like me logo Genes that share expression patterns with ODF3L1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ODF3L1 Gene

Orthologs for ODF3L1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ODF3L1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ODF3L1 34 35
  • 99.39 (n)
dog
(Canis familiaris)
Mammalia ODF3L1 34 35
  • 84.18 (n)
mouse
(Mus musculus)
Mammalia Odf3l1 34 16 35
  • 81.27 (n)
rat
(Rattus norvegicus)
Mammalia Odf3l1 34
  • 79.2 (n)
oppossum
(Monodelphis domestica)
Mammalia ODF3L1 35
  • 58 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ODF3L1 35
  • 46 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ODF3L1 35
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ODF3L1 35
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii odf3l2 34
  • 47.56 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10252 35
  • 25 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10233 35
  • 35 (a)
OneToMany
Species where no ortholog for ODF3L1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ODF3L1 Gene

ENSEMBL:
Gene Tree for ODF3L1 (if available)
TreeFam:
Gene Tree for ODF3L1 (if available)

Paralogs for ODF3L1 Gene

Paralogs for ODF3L1 Gene

(2) SIMAP similar genes for ODF3L1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ODF3L1: view

Variants for ODF3L1 Gene

Sequence variations from dbSNP and Humsavar for ODF3L1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10163112 -- 75,723,056(+) ATGTA(A/G)TAGGA upstream-variant-2KB, utr-variant-5-prime
rs111242094 -- 75,725,019(+) TACCC(A/C/G)CAATG intron-variant
rs111577076 -- 75,723,960(+) ATAAA(C/T)ACTAC upstream-variant-2KB, utr-variant-5-prime
rs111624713 -- 75,721,711(+) GGAGA(G/T)GGGGA upstream-variant-2KB
rs111685743 -- 75,724,737(+) ATGTG(A/G)GTAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ODF3L1 Gene

Variant ID Type Subtype PubMed ID
esv2749894 CNV deletion 23290073
esv2749895 CNV deletion 23290073
nsv1116463 OTHER inversion 24896259
nsv527186 CNV loss 19592680

Variation tolerance for ODF3L1 Gene

Residual Variation Intolerance Score: 84.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.37; 76.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ODF3L1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ODF3L1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ODF3L1 Gene

Disorders for ODF3L1 Gene

Relevant External Links for ODF3L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ODF3L1

No disorders were found for ODF3L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ODF3L1 Gene

Publications for ODF3L1 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ODF3L1 Gene

Sources for ODF3L1 Gene

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