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Aliases for ODF3L1 Gene

Aliases for ODF3L1 Gene

  • Outer Dense Fiber Of Sperm Tails 3 Like 1 2 3 5

External Ids for ODF3L1 Gene

Previous GeneCards Identifiers for ODF3L1 Gene

  • GC15P073804
  • GC15P073805
  • GC15P076016
  • GC15P052772

Summaries for ODF3L1 Gene

GeneCards Summary for ODF3L1 Gene

ODF3L1 (Outer Dense Fiber Of Sperm Tails 3 Like 1) is a Protein Coding gene. An important paralog of this gene is ODF3L2.

Additional gene information for ODF3L1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ODF3L1 Gene

Genomics for ODF3L1 Gene

Regulatory Elements for ODF3L1 Gene

Enhancers for ODF3L1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H075699 1.6 FANTOM5 Ensembl ENCODE dbSUPER 6.3 -22.0 -22044 5 HDGF SCRT1 MAZ RB1 KLF17 DPF2 ZNF398 ZFP69B GLIS2 ZNF692 ENSG00000261043 MIR631 MAN2C1 ODF3L1 CSPG4 SNX33 SIN3A C15orf39 ENSG00000203392
GH15H075449 1.8 FANTOM5 ENCODE dbSUPER 1.1 -270.6 -270588 8 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 NFYC MAN2C1 ENSG00000260274 SIN3A SNUPN DNM1P34 EDC3 FBXO22 LOC105370902 COMMD4 GOLGA6D
GH15H075721 1.2 Ensembl ENCODE 0.7 -2.7 -2740 0 HDGF PKNOX1 GLI4 ZNF2 ZNF143 DEK SP3 ZNF610 SMARCA4 GLIS1 SIN3A MAN2C1 PTPN9 GC15P075718 ODF3L1
GH15H075722 1.2 Ensembl ENCODE 0.7 -0.2 -182 2 HDGF ATF1 ZNF76 KLF17 BMI1 BRCA1 RAD21 RFX5 GLIS2 FOS ENSG00000261043 MIR631 ODF3L1 GC15P075718
GH15H075574 0.3 FANTOM5 2.1 -149.1 -149102 0 ENSG00000260274 MAN2C1 ODF3L1 C15orf39 UBE2Q2 SIN3A PTPN9 ENSG00000259931
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ODF3L1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ODF3L1 Gene

75,723,944 bp from pter
75,727,688 bp from pter
3,745 bases
Plus strand

Genomic View for ODF3L1 Gene

Genes around ODF3L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ODF3L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ODF3L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ODF3L1 Gene

Proteins for ODF3L1 Gene

  • Protein details for ODF3L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Outer dense fiber protein 3-like protein 1
    Protein Accession:

    Protein attributes for ODF3L1 Gene

    274 amino acids
    Molecular mass:
    31065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ODF3L1 Gene

Post-translational modifications for ODF3L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ODF3L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ODF3L1 Gene

Domains & Families for ODF3L1 Gene

Gene Families for ODF3L1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ODF3L1 Gene


Suggested Antigen Peptide Sequences for ODF3L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ODF3 family.
  • Belongs to the ODF3 family.
genes like me logo Genes that share domains with ODF3L1: view

Function for ODF3L1 Gene

Phenotypes for ODF3L1 Gene

genes like me logo Genes that share phenotypes with ODF3L1: view

Animal Model Products

CRISPR Products

miRNA for ODF3L1 Gene

miRTarBase miRNAs that target ODF3L1

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ODF3L1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ODF3L1 Gene

Localization for ODF3L1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ODF3L1 gene
Compartment Confidence
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ODF3L1 Gene

Pathways & Interactions for ODF3L1 Gene

SuperPathways for ODF3L1 Gene

No Data Available

Interacting Proteins for ODF3L1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q8IXM7-OD3L1_HUMAN ENSP00000329584 for ODF3L1 Gene via IID STRING

Gene Ontology (GO) - Biological Process for ODF3L1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ODF3L1 Gene

Drugs & Compounds for ODF3L1 Gene

No Compound Related Data Available

Transcripts for ODF3L1 Gene

mRNA/cDNA for ODF3L1 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ODF3L1 Gene

Outer dense fiber of sperm tails 3-like 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ODF3L1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ODF3L1 Gene

No ASD Table

Relevant External Links for ODF3L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ODF3L1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ODF3L1 Gene

mRNA differential expression in normal tissues according to GTEx for ODF3L1 Gene

This gene is overexpressed in Testis (x26.2).

NURSA nuclear receptor signaling pathways regulating expression of ODF3L1 Gene:


SOURCE GeneReport for Unigene cluster for ODF3L1 Gene:

genes like me logo Genes that share expression patterns with ODF3L1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ODF3L1 Gene

Orthologs for ODF3L1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ODF3L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ODF3L1 33 34
  • 99.39 (n)
(Canis familiaris)
Mammalia ODF3L1 33 34
  • 84.18 (n)
(Mus musculus)
Mammalia Odf3l1 33 16 34
  • 81.27 (n)
(Rattus norvegicus)
Mammalia Odf3l1 33
  • 79.2 (n)
(Monodelphis domestica)
Mammalia ODF3L1 34
  • 58 (a)
(Bos Taurus)
Mammalia ODF3L1 34
  • 46 (a)
(Ornithorhynchus anatinus)
Mammalia ODF3L1 34
  • 44 (a)
(Anolis carolinensis)
Reptilia ODF3L1 34
  • 39 (a)
(Danio rerio)
Actinopterygii odf3l2 33
  • 47.56 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10252 34
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10233 34
  • 35 (a)
Species where no ortholog for ODF3L1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ODF3L1 Gene

Gene Tree for ODF3L1 (if available)
Gene Tree for ODF3L1 (if available)

Paralogs for ODF3L1 Gene

Paralogs for ODF3L1 Gene

(2) SIMAP similar genes for ODF3L1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ODF3L1: view

Variants for ODF3L1 Gene

Sequence variations from dbSNP and Humsavar for ODF3L1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000691984 -- 75,726,905(+) CACCG(C/T)GTCCG intron-variant
rs1001124188 -- 75,726,516(+) TGGGG(C/G)TAATC intron-variant
rs1001687671 -- 75,725,422(+) ATAGG(A/G)GATCC intron-variant
rs1001718807 -- 75,725,196(+) ACCCT(C/G)CATAG reference, synonymous-codon
rs1002669849 -- 75,723,829(+) GGGTC(C/G)TGGGG upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ODF3L1 Gene

Variant ID Type Subtype PubMed ID
esv2749894 CNV deletion 23290073
esv2749895 CNV deletion 23290073
nsv1116463 OTHER inversion 24896259
nsv527186 CNV loss 19592680

Variation tolerance for ODF3L1 Gene

Residual Variation Intolerance Score: 84.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.37; 76.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ODF3L1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ODF3L1 Gene

Disorders for ODF3L1 Gene

Relevant External Links for ODF3L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ODF3L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ODF3L1 Gene

Publications for ODF3L1 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for ODF3L1 Gene

Sources for ODF3L1 Gene

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