ODF3B Gene
protein-coding GIFtS : 38 GCID: GC22 M050968
outer dense fiber of sperm tails 3B
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Aliasesfor ODF3B gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Outer Dense Fiber Of Sperm Tails 3B 1 2 Outer Dense Fiber Protein 3-Like Protein 32 3 ODF3L32 3 Orf2 5' To PD-ECGF/TP2 Outer Dense Fiber Protein 3B2
Export aliases for ODF3B gene to outside databases Previous GC identifers: GC22M049317 GC22M033859
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Summariesfor ODF3B gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor ODF3B gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000022.10 NC_018933.1 NT_011526.7 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ODF3B gene promoter:Sp1 HTF MIF-1 Pax-4a Arnt Other transcription factors Search SABiosciences Chromatin IP Primers for ODF3B Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q13.33 Ensembl cytogenetic band: 22q13.33 HGNC cytogenetic band: 22q13.33 ODF3B Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 22 GeneLoc Exon Structure
GeneLoc location for GC22M050968: view genomic region
(about GC identifiers )
Start: 50,968,139 bp from pter End:
50,971,009 bp from pter
Size: 2,871 bases Orientation:
minus strand
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Proteinsfor ODF3B gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ODF3B_HUMAN, A8MYP8 See
protein sequence )Recommended Name: Size : 253 amino acids; 27280 DaSecondary accessions : A0PK18Alternative splicing : 2 isoforms : A8MYP8-1 A8MYP8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ODF3B: NX_A8MYP8 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_A8MYP8 ODF3B Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_001014440.2 ENSEMBL proteins: ENSP00000384310 ENSP00000385123 ENSP00000384012 ENSP00000390712 ENSP00000393668 ENSP00000382804 Human Recombinant Protein Products: ODF3B Antibody Products: Assay Products for ODF3B:
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Protein
Domains /for ODF3B gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry A8MYP8 ProtoNet protein and cluster: A8MYP8
UniProtKB/Swiss-Prot: ODF3B_HUMAN, A8MYP8 Similarity : Belongs to the ODF3 familySimilarity : Contains 1 STPGR (Sperm-tail PG-rich) repeat
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Functionfor ODF3B gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ODF3B (NM_001014440 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ODF3B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ODF3B
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Pathways & Interactionsfor ODF3B gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ODF3B
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Drugs & Compoundsfor ODF3B gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ODF3B ODF3B
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Transcriptsfor ODF3B gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
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Primers from
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QIAGEN
)About This Section REFSEQ mRNAs for ODF3B gene: NM_001014440.3 Unigene Cluster for ODF3B:
Outer dense fiber of sperm tails 3B Hs.531314 [show with all ESTs ] Unigene Representative Sequence: S72487 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000468249 ENST00000401779 (uc003bmg.2 ) ENST00000403326 ENST00000405135 ENST00000428989 ENST00000463472 ENST00000469660 ENST00000437588 ENST00000329363 (uc003bmh.2 )Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ODF3B (NM_001014440 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ODF3B Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ODF3B
Additional cDNA sequence: BC127934.1 BC127935.1 S72487.1
14 DOTS entries : DT.92455500 DT.446158
DT.100879983 DT.95259846 DT.85105232 DT.97834969 DT.120637975 DT.86857045 DT.120638065 DT.92326825 DT.100879980 DT.100879991 DT.40198457 DT.453568 24/481 AceView cDNA sequences (see all 481 ):
AW513414 CA308094 BM682370 BM709018 CR615106 BX366117 BU730919 BM893839 BQ934956 BM923773 AW014906 CD743035 CR604852 BC052211 CR608324 CB150936 CA306381 CA309026 BM725987 CD368368 CR611811 BI909247 CR613512 CR616233 GeneLoc Exon Structure
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Expression for ODF3B gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ODF3B expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ACCGTGCGCG
About this image ODF3B expression in embryonic tissues and stem cells About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category Posterior foregut-like cells (A scalable, suspensi... )Expression: Experimental details:
In-situ hybridization
See ODF3B Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ODF3B SOURCE GeneReport for Unigene cluster: Hs.531314 SABiosciences Custom PCR Arrays for ODF3B Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
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Orthologsfor ODF3B gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for ODF3B gene from 3/15 species (see all 15 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
lizard Reptilia ODF3B6
--
57(a)
1 ↔ 1
GL343682.1(129620-132646)
zebrafish Actinopterygii odf3b6
outer dense fiber of sperm tails 3B
51(a)
1 → many
18(7074673-7083233)
fruit fly Insecta CG80866 6
--
4(a) 26(a)
possible orthologpossible ortholog
2L(8244160-8257502) 3R(19520936-19522000)
ENSEMBL Gene Tree for ODF3B (if available)TreeFam Gene Tree for ODF3B (if available)
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Paralogsfor ODF3B gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ODF3B gene ODF3 2 ODF3L2 2 ODF3L1 2 5 SIMAP similar genes for ODF3B using alignment to 6 protein entries: ODF3B_HUMAN (see all proteins ):orf2 5' to PD-ECGF/TP ODF3 ODF3L2 orf3 5' of PD-ECGF/TP ODF3L1 About GeneDecksing
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Genomic Variantsfor ODF3B gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 22 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for ODF3B (50968139 - 50971009 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ODF3B 2 CNVs 4139 5192
SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor ODF3B gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About MalaCards About GeneDecksing Human Genome Epidemiology (HuGE) Navigator: ODF3B (3 documents) Export disorders for ODF3B gene to outside databases
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Publicationsfor ODF3B gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ODF3B gene integrated from 9 sources :(articles sorted by number of sources associating them with ODF3B) Utopia : connect your pdf to the dynamic
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) The DNA sequence of human chromosome 22. (PubMed id 10591208) 1 , 2 (1999) Genetic risk and a primary role for cell-mediated immu ne mechanisms in multiple sclerosis. (PubMed id 21833088) 1 (2011) Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086) 1 (2010) Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121) 1 (2009) Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. (PubMed id 19862010) 1 (2009) Expressed sequence tag analysis of adult human lens for the NEIBank project: over 2000 non-redundant transcripts, novel genes and splice variants. (PubMed id 12107413) 1 (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 (2002) Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548) 1 (1996) Structural properties of 3.0 kb and 3.2 kb transcripts encoding platelet-derived endothelial cell growth factor/thymidine phosphorylase in A431 cells. (PubMed id 8038210) 1 (1994)
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External Searches for ODF3B gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ODF3B gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ODF3B gene
(According to HUGE )
About This Section --
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Specialized Databases showing ODF3B gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for ODF3B Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ODF3B gene: ODF3B GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ODF3B gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ODF3B OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for ODF3B Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ODF3B OriGene 3'-UTR Clone for ODF3B OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ODF3B OriGene Custom Protein Services for ODF3B OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ODF3B Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ODF3B QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
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ODF3B Proteins, Antibodies, CLIAs, and ELISAs
ThermoFisher Antibodies for ODF3B
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ODF3B
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Negative
Selective marker
Curated
In-situ hybridization
