ODF2L Gene
protein-coding GIFtS: 43
GCID: GC01M086808
|
|
outer dense fiber of sperm tails 2-like
| |
Aliases
for ODF2L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Outer Dense Fiber Of Sperm Tails 2-Like1 2 | | KIAA12291 3 | | RP5-977L11.12 | | DJ977L11.11 | | Outer Dense Fiber Protein 2-Like2 |
Export aliases for ODF2L gene to outside databasesPrevious GC identifers: GC01M086527 GC01M084923 |
Summaries
for ODF2L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ODF2L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ODF2L gene promoter:
HFH-3 HOXA9 HOXA9B Pbx1a AML1a FOXD3 AP-4 FOXI1 Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ODF2L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODF2L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p22.3 Ensembl cytogenetic band: 1p22.3 HGNC cytogenetic band: 1p22.3ODF2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M086808: view genomic region
(about GC identifiers)
Start:
|
86,812,507 bp from pter |
End:
|
86,862,025 bp from pter |
Size:
|
49,519 bases |
Orientation:
|
minus strand |
|
Proteins
for ODF2L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ODF2L_HUMAN, Q9ULJ1 (See
protein sequence)Recommended Name: Outer dense fiber protein 2-like Size: 636 amino acids; 73728 Da
Sequence caution: Sequence=AAH29420.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=AAH47368.1; Type=Erroneous termination; Positions=397; Note=Translated as Glu; Sequence=AK308351;Type=Frameshift; Positions=296; Sequence=BAA86543.1; Type=Erroneous initiation; Note=Translation N-terminallyshortened;
Secondary accessions: A8MU56 B4E037 Q05C40 Q5BJG5 Q5TBX3 Q5TBX4 Q86X31Alternative splicing: 6 isoforms: Q9ULJ1-1 Q9ULJ1-2 Q9ULJ1-3 Q9ULJ1-4 Q9ULJ1-5 Q9ULJ1-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ODF2L: NX_Q9ULJ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9ULJ1
ODF2L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001007023.2 NP_001171694.1 NP_001171695.1 NP_065780.2
ENSEMBL proteins: ENSP00000436849 ENSP00000359600 ENSP00000433092 ENSP00000437043 ENSP00000294678 ENSP00000431920 ENSP00000433632 ENSP00000432834 ENSP00000378220 ENSP00000435878 ENSP00000437292 ENSP00000432632 ENSP00000359597 ENSP00000320165 ENSP00000359598 ENSP00000378219
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005813 | centrosome |
IDA | -- |
ODF2L for ontologies About GeneDecksing
ODF2L Antibody Products:
Assay Products for ODF2L: |
Protein
Domains /
Families
for ODF2L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ODF2L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9ULJ1ProtoNet protein and cluster: Q9ULJ1 UniProtKB/Swiss-Prot: ODF2L_HUMAN, Q9ULJ1Similarity: Belongs to the ODF2 family |
Function
for ODF2L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ODF2L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODF2L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODF2L |
|
Pathways & Interactions
for ODF2L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ODF2L
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5 Interacting proteins for ODF2L (Q9ULJ13 ENSP000003595984) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ODF2L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ODF2L
Search CenterWatch for drugs/clinical trials and news about ODF2L
|
Transcripts
for ODF2L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ODF2L gene (4 alternative transcripts): NM_001007022.2 NM_001184765.1 NM_001184766.1 NM_020729.2 Unigene Cluster for ODF2L: Outer dense fiber of sperm tails 2-like Hs.149360 [show with all ESTs]Unigene Representative Sequence: AB03305518/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26): ENST00000459999 ENST00000359242(uc001dll.2) ENST00000460698 ENST00000462648
ENST00000294678(uc001dlm.2) ENST00000531412 ENST00000476054 ENST00000473792
ENST00000524695 ENST00000472144 ENST00000463933 ENST00000534092 ENST00000496592
ENST00000488879 ENST00000479890 ENST00000486557 ENST00000472368 ENST00000480440
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ODF2L (NM_001184765) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ODF2L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODF2L |
Additional cDNA sequence: AB033055.1 AK302792.1 AK303209.1 AK308351.1 BC009779.1 BC012579.1 BC026105.2 BC029420.1 BC047368.1 BC091490.1 24 DOTS entries: DT.99939491 DT.100675677 DT.92428840 DT.406260 DT.100792291 DT.87014957 DT.99977796 DT.102825547 DT.121445945 DT.40115136 DT.443632 DT.75129094 DT.70105106 DT.92428842 DT.99949602 DT.121445947 DT.121446015 DT.95087540 DT.100008825 DT.442048 DT.443633 DT.95072764 DT.99934490 DT.95347735 24/172 AceView cDNA sequences (see all 172): AI382078 BM983457 BX955119 CB148065 AI473444 CA446491 BM150300 BQ028973 AW452022 CA949998 BE674715 AI886345 BM971230 AA521186 AW172516 CR591511 AA301374 CF145486 BQ894001 AA825161 AA552255 AI623670 AI376178 BU686861
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ODF2L (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ODF2L
|
Expression
for ODF2L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ODF2L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCACGTGTAT
About this image
See ODF2L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ODF2L
SOURCE GeneReport for Unigene cluster: Hs.149360
SABiosciences Custom PCR Arrays for ODF2L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ODF2L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ODF2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODF2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODF2L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODF2L |
Orthologs
for ODF2L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ODF2L gene from 2/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ODF2L1 |
outer dense fiber of sperm tails 2-like |
58.07(n)
41.54(a) |
|
424524 XM_422361.3 XP_422361.3 |
lizard
(Anolis carolinensis) |
Reptilia |
ODF2L6 |
-- |
42(a) |
1 ↔ 1 |
4(97898362-97948965) |
ENSEMBL Gene Tree for ODF2L (if available)
TreeFam Gene Tree for ODF2L (if available) |
Paralogs
for ODF2L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ODF2L gene
- ODF22
1 SIMAP similar gene for ODF2L using alignment to 12 protein entries: ODF2L_HUMAN (see all proteins):ODF2
ODF2L for paralogs About GeneDecksing
|
Genomic Variants
for ODF2L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ODF2L (86812507 - 86862025 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ODF2L: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ODF2L |
|
Disorders
/ Diseases
for ODF2L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ODF2L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ODF2L gene integrated from 9 sources:
(articles sorted by number of sources associating them with ODF2L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for ODF2L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ODF2L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ODF2L gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ODF2L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ODF2L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ODF2L gene:
Search GeneIP for patents involving ODF2L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ODF2L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ODF2L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ODF2L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ODF2L | | | OriGene Protein Over-expression Lysate for ODF2L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ODF2L | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ODF2L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ODF2L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODF2L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ODF2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODF2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODF2L |
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