ODF2 Gene
protein-coding GIFtS: 55
GCID: GC09P131218
|
|
outer dense fiber of sperm tails 2(Previous name: outer dense fibre of sperm tails 2 )
| |
Aliases
for ODF2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Outer Dense Fiber Of Sperm Tails 21 2 | | Cenexin 12 | | ODF841 2 5 | | Outer Dense Fiber Of Sperm Tails, 84-KD2 | | CT1341 2 | | Outer Dense Fiber Protein 22 | | Outer Dense Fibre Of Sperm Tails 21 | | Sperm Tail Structural Protein2 | | ODF2/12 | | Cenexin3 | | ODF2/22 | | Outer Dense Fiber Of Sperm Tails Protein 23 | | Cancer/Testis Antigen 1342 | | |
Export aliases for ODF2 gene to outside databasesPrevious GC identifers: GC09P122333 GC09P122864 GC09P124672 GC09P126595 GC09P126596 GC09P128297 GC09P130258 GC09P100831 |
Summaries
for ODF2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ODF2:
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece ofthe sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as inprotecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fiberslead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins.Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encodeproteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucialfor the formation of microtubule organizing centers. (provided by RefSeq, Oct 2010)
UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6Function: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures locatedon the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintainthe passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on spermmotility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages ofmother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to thecentrosomes. Required for the formation and/or maintenance of normal CETN1 assembly
Gene Wiki entry for ODF2
|
Genomic Views
for ODF2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ODF2 gene promoter:
HOXA9B HOXA9 Nkx2-5 Tal-1beta Meis-1b E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for ODF2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODF2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34ODF2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P131218: view genomic region
(about GC identifiers)
Start:
|
131,217,466 bp from pter |
End:
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131,263,239 bp from pter |
Size:
|
45,774 bases |
Orientation:
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plus strand |
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Proteins
for ODF2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6 (See
protein sequence)Recommended Name: Outer dense fiber protein 2 Size: 829 amino acids; 95401 Da
Subunit: Self-associates. Associates with microtubules and forms a fibrillar structure partially linked to themicrotubule network. Interacts via its C-terminus with PLK1. Interacts with ODF1 (By similarity)
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton,centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Localized at the microtubule organizing centers ininterphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles
Sequence caution: Sequence=AAC08409.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B1AND3 B4DRK4 B4DX73 B4DZ02 E7EWL2 F5H6J4 O14721 O60631 Q1W2J6 Q6UN26 Q7Z5I6Q96FN2Alternative splicing: 10 isoforms: Q5BJF6-1 Q5BJF6-2 Q5BJF6-3 Q5BJF6-4 Q5BJF6-5 Q5BJF6-6 Q5BJF6-7 Q5BJF6-8 Q5BJF6-9 Q5BJF6-10 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ODF2: NX_Q5BJF6
Post-translational modifications:
Tyrosine phosphorylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5BJF6
ODF2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (11 alternative transcripts):
NP_001229281.1 NP_001229282.1 NP_001229283.1 NP_002531.3 NP_702910.1 NP_702911.1 NP_702913.1 NP_702914.1 NP_702915.1 NP_702917.1 NP_702918.1
ENSEMBL proteins: ENSP00000361901 ENSP00000390819 ENSP00000361893 ENSP00000395489 ENSP00000377161 ENSP00000394506 ENSP00000403453 ENSP00000415290 ENSP00000407852 ENSP00000361877 ENSP00000377166 ENSP00000437579 ENSP00000361882 ENSP00000342581 ENSP00000307781 ENSP00000396687 ENSP00000443178 Reactome Protein details: Q5BJF6
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ODF2 for ontologies About GeneDecksing
ODF2 Antibody Products:
Assay Products for ODF2: |
Protein
Domains /
Families
for ODF2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ODF2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5BJF6ProtoNet protein and cluster: Q5BJF6 UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6Similarity: Belongs to the ODF2 family |
Function
for ODF2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6Function: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures locatedon the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintainthe passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on spermmotility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages ofmother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to thecentrosomes. Required for the formation and/or maintenance of normal CETN1 assembly Genatlas biochemistry entry for ODF2:outer dense fiber protein 2,component of the filamentous structure of the sperm tail,expressed in round spermatidsextending to about half the principal piece of tail sperm,involved in sperm tail function and motility
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 (see all 14)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): ODF2 (NM_153435) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ODF2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODF2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODF2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ODF2 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for ODF2:
Animal Models:
10 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Odf2):
ODF2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ODF2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Recruitment of mitotic centrosome proteins and complexes | | | 2 | Cell Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/8 
Reactome Pathways for ODF2 (see all 8)
ODF2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ODF2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/60 Interacting proteins for ODF2 (Q5BJF62, 3 ENSP000003077814) via UniProtKB, MINT, STRING, and/or I2D (see all 60)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
ODF2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ODF2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ODF2
Search CenterWatch for drugs/clinical trials and news about ODF2 / ODFP2
|
Transcripts
for ODF2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ODF2 gene (11 alternative transcripts): NM_001242352.1 NM_001242353.1 NM_001242354.1 NM_002540.4 NM_153432.1 NM_153433.1 NM_153435.1 NM_153436.1 NM_153437.2 NM_153439.1 NM_153440.1 Unigene Cluster for ODF2: Outer dense fiber of sperm tails 2 Hs.129055 [show with all ESTs]Unigene Representative Sequence: NM_00254018/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000372814(uc022boj.1 uc004bva.3) ENST00000469582 ENST00000497812
ENST00000444993 ENST00000372807(uc011mba.2 uc010myb.3) ENST00000421776
ENST00000393527(uc004bvh.3) ENST00000444119 ENST00000434106 ENST00000446274
ENST00000432065 ENST00000372791(uc004bve.3) ENST00000470061 ENST00000494663
ENST00000483070 ENST00000488909 ENST00000393533(uc011maz.2) ENST00000546203(uc010myc.3 uc011mbf.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 (see all 14)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 7): ODF2 (NM_153435) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ODF2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODF2 |
Additional cDNA sequence: AF012549.1 AF053970.1 AK093367.1 AK299303.1 AK300793.1 AK301754.1 AK301842.1 AK301855.1 AK302684.1 AK308278.1 AK309917.1 AY319414.1 AY366499.1 BC010629.1 BC012785.2 BC091500.1 DQ444713.1 DQ444714.1 24/31 DOTS entries (see all 31): DT.100027904 DT.441028 DT.101984564 DT.121155149 DT.40206733 DT.100812960 DT.101984565 DT.95155916 DT.91757262 DT.97847388 DT.95155907 DT.121155171 DT.91757256 DT.91757259 DT.40251440 DT.100812956 DT.40213676 DT.91757257 DT.91757267 DT.95155914 DT.95155926 DT.100768846 DT.40119153 DT.95155917 24/265 AceView cDNA sequences (see all 265): AU185842 AL138381 BE869324 NM_153437 BX283924 BM853853 CB123358 NM_002540 AL043836 BX375038 BI829334 BG110128 AW614067 BM824222 BM928430 BG108561 BI826203 BU727859 AI653099 AI750706 BQ226625 CB156479 BQ436203 AI634153
GeneLoc Exon Structure
5/25 Alternative Splicing Database (ASD) splice patterns (SP) for ODF2 (see all 25) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | |
| ExUns: | 9f | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | · | 23c | · | 23d | ^ | 24a | · | 24b | · | 24c | · |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | - | | - | | | | - | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | - | | - | | | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | - | | - | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | |
| ExUns: | 24d | ^ | 25 | ^ | 26a | · | 26b |
|---|
|
| SP1: | | | | | | | | | |
| SP2: | | | | | | | | | |
| SP3: | | | | | | | | | |
| SP4: | | | | | | | | | |
| SP5: | | | | | | | | |
ECgene alternative splicing isoforms for ODF2
|
Expression
for ODF2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ODF2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTTTGCTCC
About this image
See ODF2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ODF2
SOURCE GeneReport for Unigene cluster: Hs.129055
UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6Tissue specificity: Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids.Detected in the middle piece and extends to about half the principal piece of the sperm tails
SABiosciences Custom PCR Arrays for ODF2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ODF2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ODF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODF2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODF2 |
Orthologs
for ODF2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ODF2 gene from 5/14 species (see all 14) About this table
ENSEMBL Gene Tree for ODF2 (if available)
TreeFam Gene Tree for ODF2 (if available) |
Paralogs
for ODF2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ODF2 gene
- ODF2L2
1 SIMAP similar gene for ODF2 using alignment to 12 protein entries: ODFP2_HUMAN (see all proteins):ODF2L
ODF2 for paralogs About GeneDecksing
|
Genomic Variants
for ODF2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ODF2 (131217466 - 131263239 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ODF2
2 Indels: 29059 47647 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ODF2 |
|
Disorders
/ Diseases
for ODF2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ODF2 for disorders About GeneDecksing
OMIM gene information: 602015
OMIM disorders: --
2  diseases for ODF2: About MalaCardsepididymitis infertility
Human Genome Epidemiology (HuGE) Navigator: ODF2 (1 document)
Export disorders for ODF2 gene to outside databases
|
Publications
for ODF2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ODF2 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with ODF2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. (PubMed id 16966375)1, 2 Soung N.-K....Lee K.S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa. (PubMed id 10381817)1, 2 Petersen C.... Hoyer-Fender S. (1999)
- Human outer dense fiber gene, ODF2, localizes to chromosome 9q34. (PubMed id 10072582)1, 3 Shao X....van der Hoorn F.A. (1998)
- Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27. (PubMed id 9045620)1, 3 Shao X....van der Hoorn F.A. (1997)
- Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860)1 Chuang J.Y....Hung J.J. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Trichoplein controls microtubule anchoring at the cen trosome by binding to Odf2 and ninein. (PubMed id 21325031)1 Ibi M....Inagaki M. (2011)
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External Searches for ODF2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ODF2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ODF2 gene
(According to HUGE)
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Specialized Databases showing ODF2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ODF2 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for ODF2 gene:
Search GeneIP for patents involving ODF2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ODF2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ODF2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ODF2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ODF2 | | | OriGene Protein Over-expression Lysate for ODF2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ODF2 | | OriGene 3'-UTR Clone for ODF2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ODF2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ODF2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ODF2 | | OriGene Custom Protein Services for ODF2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ODF2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ODF2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODF2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ODF2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODF2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODF2 |
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| | | | Search Tocris compounds for ODF2 |
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 | | | ODF2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODF2 |
|  |  |  | | | | Search ThermoFisher Antibodies for ODF2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODF2 |
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