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ODF2 Gene

protein-coding GIFtS: 54

GC09P130258

outer dense fiber of sperm tails 2
(Previous name: outer dense fibre of sperm tails 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
Cenexin ^³
FLJ44866 ^²
MGC111096 ^²
MGC9034 ^²
ODF2/1 ^²
ODF2/2 ^²
ODF84 ^¹, ², ⁵
OTTHUMP00000022273 ^²
OTTHUMP00000022274 ^²

Descriptions
Outer dense fiber of sperm tails protein 2 ^³
cenexin 1 ^²
outer dense fiber of sperm tails 2 ^²
outer dense fiber of sperm tails, 84-kD ^²
outer dense fibre of sperm tails 2 ^¹, ²
sperm tail structural protein ^²

External Ids
HGNC: 8114¹
Entrez Gene: 4957²
UniProtKB: Q5BJF6³
Ensembl: ENSG00000136811⁷

Search outside databases for aliases for ODF2 gene

Previous GC identifers: GC09P122333 GC09P122864 GC09P124672 GC09P126595 GC09P126596 GC09P128297

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ODF2:

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece

and principal piece of the sperm tail. The fibers function in maintaining the elastic structure

and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal

transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and

infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein

isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants

have been fully described. [provided by RefSeq]

UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6

Function: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are

filamentous structures located on the outside of the axoneme in the midpiece and principal piece

of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic

recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as general

scaffold protein that is specifically localized at the distal/subdistal appendages of mother

centrioles. Component of the centrosome matrix is required for the localization of PLK1 and NIN to

the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly

Gene Wiki entry for ODF2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ODF2 gene

Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34

ODF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P130258: (about GC identifiers)

Start:	130,258,157 bp from pter
End:	130,303,060 bp from pter
Size:	44,904 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000009.10 NT_008470.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6 (See protein sequence)

Recommended Name: Outer dense fiber protein 2

Size: 829 amino acids; 95401 Da

Subunit: Self-associates. Associates with microtubules and forms a fibrillar structure partially

linked to the microtubule network. Interacts via its C-terminus with PLK1. Interacts with ODF1 (By

similarity)

Subcellular location: Centrosome. Cell projection, cilium. Note=Localized at the microtubule

organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal

appendages of mother centrioles

Secondary accessions: B4DRK4 B4DZ02 O14721 O60631 Q1W2J6 Q6UN26 Q7Z5I6 Q96FN2

Alternative splicing: 6 isoforms: Q5BJF6-1 Q5BJF6-2 Q5BJF6-3 Q5BJF6-4 Q5BJF6-5 Q5BJF6-6

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_002531.3 NP_702915.1

ENSEMBL proteins:

ENSP00000361901 ENSP00000361882 ENSP00000361877 ENSP00000377166 ENSP00000361893 ENSP00000307781

ENSP00000377161 ENSP00000342581

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Cenexin1/ODF2)
	Human Recombinant Proteins from Abnova (ODF2)

OriGene Purified Recombinant Human Protein: ODF2

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005737	cytoplasm	IDA	18029348
GO:0005813	centrosome	IEA	--
GO:0005874	microtubule	IEA	--
GO:0005929	cilium	IEA	--

About this table

Antibodies for ODF2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ODF2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Cenexin1/ODF2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ODF2)
	Novus Biologicals Antibodies for ODF2

Assays for ODF2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q5BJF6

UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6

Similarity: Belongs to the ODF2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ODF2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153437

Applied Biosystems Silencer® siRNAs for ODF2

Sigma-Aldrich siRNA for ODF2

Sigma-Aldrich shRNA for ODF2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ODF2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002540
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002540
untagged cDNA clones in CMV expression vector (see all 3): NM_002540

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002540

UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6

Function: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are

filamentous structures located on the outside of the axoneme in the midpiece and principal piece

of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic

recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as general

scaffold protein that is specifically localized at the distal/subdistal appendages of mother

centrioles. Component of the centrosome matrix is required for the localization of PLK1 and NIN to

the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly

Genatlas biochemistry entry for ODF2:

outer dense fiber protein 2,component of the filamentous structure of the sperm tail,expressed in

round spermatids extending to about half the principal piece of tail sperm,involved in sperm tail

function and motility

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Odf2):

lethality-prenatal/perinatal

reproductive system

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005198	structural molecule activity	TAS	10072582

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ODF2

1 Interacting protein for ODF2 (ENSP00000361882³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ODF1	ENSP00000285402³	STRING (score=.896)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	IEA	--
GO:0007283	spermatogenesis	IEA	--
GO:0030154	cell differentiation	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ODF2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ODF2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153437

Sigma-Aldrich siRNA for ODF2

Sigma-Aldrich shRNA for ODF2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002540 NM_153437

REFSEQ mRNAs for ODF2 gene (2 alternative transcripts):

NM_002540.3 NM_153437.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002540 NM_153437

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002540
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002540
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_002540

Additional cDNA sequence:

AF012549.1 AF053970.1 AK093367.1 AK126816.1 AK295662.1 AK299303.1 AK300793.1 AK301754.1

AK301842.1 AK301855.1 AK302684.1 AK308278.1 AK309917.1 AY319414.1 AY366499.1 BC010629.1

BC012785.2 BC091500.1 DQ444713.1 DQ444714.1

24/31 DOTS entries (see all 31 ):

DT.100027904 DT.441028 DT.101984564 DT.121155149 DT.40206733 DT.100812960 DT.101984565 DT.97847388

DT.91757262 DT.95155916 DT.95155907 DT.121155171 DT.91757256 DT.91757259 DT.100812956 DT.40213676

DT.40251440 DT.100768846 DT.91757257 DT.91757267 DT.95155914 DT.95155926 DT.40119153 DT.95155917

24/265 AceView cDNA sequences (see all 265 ):

BE793816 BI827718 BM928430 CB123358 BE869324 AI750706 AU185842 BQ226625

BM835331 AI671833 CD244287 AW438804 AL138381 BI826203 BM720731 BQ436203

BG110128 AI634153 BX283924 BU727859 AW614067 AI653099 BP374653 BX375038

highest scoring ESTs for ODF2:

AA034010 AI150254 AA034009 AA149882 AA150062 AA328560 AA331928 AA353533 AA437014 AA470814

Unigene Cluster for ODF2:

Outer dense fiber of sperm tails 2

Hs.129055 [show with all ESTs]

Unigene Representative Sequence: NM_002540

GeneLoc Exon Structure

5/25 Alternative Splicing Database (ASD) splice patterns (SP) for ODF2 (see all 25 )

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2a	·	2b	·	2c	·	2d	·	2e	^	3a	·	3b	·	3c	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	·	9c	·	9d	·	9e	·
SP1:											-		-		-		-		-		-		-		-		-								-						-
SP2:											-		-		-		-		-		-		-		-		-		-				-		-						-
SP3:																					-		-		-		-						-		-		-
SP4:																											-						-		-		-				-
SP5:											-		-		-		-		-		-		-		-		-		-				-		-		-

ExUns:	9f	^	10a	·	10b	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19	^	20	^	21a	·	21b	^	22a	·	22b	^	23a	·	23b	·	23c	·	23d	^	24a	·	24b	·	24c	·
SP1:											-												-										-				-		-		-				-		-
SP2:											-												-										-				-		-		-				-		-
SP3:											-												-										-				-		-		-				-		-
SP4:											-												-										-
SP5:											-												-										-

ExUns:	24d	^	25	^	26a	·	26b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for ODF2

8 Ensembl transcripts including schematic representations:

ENST00000372814 ENST00000372796 ENST00000372791 ENST00000393533 ENST00000372807 ENST00000303890

ENST00000393527 ENST00000351030

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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ODF2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ODF2

¹ / ² / ³

7 probe-sets matching ODF2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
53791_at²^{, 3}	U95-B	1	1.00	1.00	0.85	1.47	AA034010	1.00	1.00	1.00	1
41068_at²^{, 3}	U95-A	1	1.00	1.00	0.89	0.43	AF012549	0.80	1.00	0.91	1
91980_at²^{, 3}	U95-D	1	0.38	1.00	0.94	1.13	AI150254	1.00	1.00	1.00	1
210415_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF053970	0.60	1.00	0.82	1
225617_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AL138382	0.80	1.00	0.91	1
210415_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
225617_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ODF2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ACTTTGCTCC

SOURCE GeneReport for Unigene cluster: Hs.129055
Expression variation in blood from EXPOLDB for ODF2
UniProtKB/Swiss-Prot: ODFP2_HUMAN, Q5BJF6
Tissue specificity: Testis-specific (at protein level). Highly expressed in cytoplasm of step 2
round spermatids. Detected in the middle piece and extends to about half the principal piece of
the sperm tails

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ODF2 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ODF2¹	--	outer dense fiber of sperm tails 2	92.8(n) 98.51(a)	491315 XM_856592.1 XP_861685.1
chimpanzee (Pan troglodytes)	ODF2¹	--	outer dense fiber of sperm tails 2	99.25(n) 99.63(a)	464769 XM_001158777.1 XP_001158777.1
cow (Bos taurus)	ODF2¹	--	outer dense fiber of sperm tails 2	91.04(n) 96.13(a)	539043 NM_001038180.1 NP_001033269.1
rat (Rattus norvegicus)	Odf2¹	--	outer dense fiber of sperm tails 2	88.68(n) 96.97(a)	29479 NM_017213.2 NP_058909.2
mouse (Mus musculus)	Odf2^{1, 5}	2 (19.00 cM)⁵	outer dense fiber of sperm tails 2^{1, 5}	89.08(n)¹ 96.81(a)¹	18286¹ NM_013615.2¹ NP_038643.1¹ AB097861⁵ AF000968⁵ (see all 23)

About this table Species with no ortholog for ODF2

ENSEMBL Gene Tree for ODF2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ODF2 gene

ODF2L²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/245 NCBI SNPs in ODF2 are shown (see all 245 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 53)

AB	SNP ID	Valid	Chr 9 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3088209^1,2	A,C,F,H,O	130303271(-)	`AAGCAG/ATCCTT`	1	--	ng3¹		14		NS MN EU EA WA NA	916
	rs16930426^1,2	C,F,H	130300629(+)	`TGGGAC/GCCTGG`	1	T/S	mis¹ ese³		11		NA EU EA WA	964
	rs10819384^1,2	A,C,F	130258034(+)	`GACCCG/AGCCAG`	2	--	ng5¹		2		MN EA	1252
	rs1133750^1,2	C,F	130302778(+)	`TAAGCA/GCCATC`	1	--	ut3¹		5		MN EU EA WA	604
--	rs4837274^1,2	A,C	130297023(+)	`CACCCA/GAGACT`	2	--	ng3¹ int¹		0	--	--	--	--
	rs28372669^1,2	C,F	130258097(+)	`GTGGGC/TGGCCC`	2	--	ng5¹		2		MN EA	1252
--	rs7465928^1,2	C	130257555(+)	`aggctC/Gaggca`	2	--	ng5¹		0	--	--	--	--
--	rs28372668^1,2	F	130257782(+)	`GGAGA-/GAGGCCG`	2	--	ng5¹ trp³		2		MN EA	1252
--	rs6478832^1,2	C	130262362(+)	`CTAAGA/GACCCT`	2	--	ut5¹ int¹ ese³		0	--	--	--	--
	rs4512487^1,2	C,F,H	130275142(+)	`AAAACG/AGTAGG`	2	T/T	syn¹		2		EU NA	148

About this table

HapMap Linkage Disequilibrium images for ODF2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602015

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/14 PubMed articles for ODF2 gene (see all 14 ):

Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. (PubMed id 16966375)^{3, 4} Soung N.-K....Lee K.S. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa. (PubMed id 10381817)^{3, 4} Petersen C.... Hoyer-Fender S. (1999)
Human outer dense fiber gene, ODF2, localizes to chromosome 9q34. (PubMed id 10072582)^{2, 3} Shao X....van der Hoorn F.A. (1998)
Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27. (PubMed id 9045620)^{2, 3} Shao X....van der Hoorn F.A. (1997)
Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. (PubMed id 19386263)³ Soung N.K....Lee K.S. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)³ Beausoleil S.A....Gygi S.P. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)⁴ Humphray S.J.... Dunham I. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4957	HGNC: 8114	AceView: ODF2	Ensembl:ENSG00000136811	euGenes: HUgn4957
ECgene: ODF2	H-InvDB: ODF2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for ODF2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ODF2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ODF2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ODF2		Antibodies for ODF2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ODF2		Browse small molecules at Sigma-Aldrich
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Antibodies for ODF2

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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ODF2 Gene at Home site.
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ODF2 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for ODF2

Summaries
for ODF2

Genomic Location
for ODF2

Proteins
for ODF2

Protein Domains/
Families
for ODF2

Gene Function
for ODF2

Pathways & Interactions
for ODF2

Drugs & Compounds
for ODF2

Transcripts
for ODF2

Expression
for ODF2

Orthologs
for ODF2

Paralogs
for ODF2

SNPs/Variants
for ODF2

Disorders & Mutations
for ODF2

Medical News
for ODF2

Publications
for ODF2

Search for ODF2

Genome Databases showing ODF2

Other Databases showing ODF2

Specialized Databases showing ODF2

Licensable Technologies
for ODF2

Services
for ODF2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ODF2 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor ODF2

Summariesfor ODF2

Genomic Locationfor ODF2

Proteinsfor ODF2

Protein Domains/Familiesfor ODF2

Gene Functionfor ODF2

Pathways & Interactionsfor ODF2

Drugs & Compoundsfor ODF2

Transcriptsfor ODF2

Expression for ODF2

Orthologsfor ODF2

Paralogsfor ODF2

SNPs/Variantsfor ODF2

Disorders & Mutationsfor ODF2

Medical Newsfor ODF2

Publicationsfor ODF2

Search for ODF2

Genome Databases showing ODF2

Other Databases showing ODF2

Specialized Databases showing ODF2

Licensable Technologiesfor ODF2

Servicesfor ODF2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ODF2

Summaries
for ODF2

Genomic Location
for ODF2

Proteins
for ODF2

Protein Domains/
Families
for ODF2

Gene Function
for ODF2

Pathways & Interactions
for ODF2

Drugs & Compounds
for ODF2

Transcripts
for ODF2

Expression
for ODF2

Orthologs
for ODF2

Paralogs
for ODF2

SNPs/Variants
for ODF2

Disorders & Mutations
for ODF2

Medical News
for ODF2

Publications
for ODF2

Licensable Technologies
for ODF2

Services
for ODF2