Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ODAM Gene

protein-coding   GIFtS: 52
GCID: GC04P071062

Odontogenic, Ameloblast Asssociated

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Odontogenic, Ameloblast Asssociated1 2
APIN2 3
Odontogenic Ameloblast-Associated Protein2
Apin3

External Ids:    HGNC: 260431   Entrez Gene: 549592   Ensembl: ENSG000001092057   OMIM: 6148435   UniProtKB: A1E9593   

Export aliases for ODAM gene to outside databases

Previous GC identifers: GC04P071098 GC04P066865


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ODAM Gene: 
ODAM (odontogenic, ameloblast asssociated) is a protein-coding gene. Diseases associated with ODAM include calcifying epithelial odontogenic tumor, and ossifying fibroma, and among its related super-pathways are Packaging Of Telomere Ends.

UniProtKB/Swiss-Prot: ODAM_HUMAN, A1E959
Function: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that
results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of
mineralization process

Gene Wiki entry for ODAM Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_022778.16  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ODAM gene promoter:
         C/EBPbeta   CBF-C   POU2F1   CBF-A   CBF-B   POU2F1a   CP1A   CP1C   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidODAM promoter sequence
   Search SABiosciences Chromatin IP Primers for ODAM

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODAM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.3   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13.3

ODAM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ODAM gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P071062:  view genomic region     (about GC identifiers)

Start:
71,062,213 bp from pter      End:
71,070,293 bp from pter
Size:
8,081 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ODAM_HUMAN, A1E959 (See protein sequence)
Recommended Name: Odontogenic ameloblast-associated protein precursor  
Size: 279 amino acids; 30777 Da
Subcellular location: Secreted (By similarity)
Miscellaneous: ODAM protein is the unique constituent of calcifying epithelial odontogenic tumors (CEOTs), also
known as Pindborg tumors. CEOTs are benign but locally aggressive pathologic entities arising mainly in the
mandible and commonly associated with an unerupted or embedded tooth. They are characterized by the presence of
squamous-cell proliferation, calcification, and, notably, amyloid deposits
Sequence caution: Sequence=BAA91226.1; Type=Erroneous initiation;
Secondary accessions: Q8WWE5 Q9NWZ9

Explore the universe of human proteins at neXtProt for ODAM: NX_A1E959

Explore proteomics data for ODAM at MOPED 

Post-translational modifications:

  • UniProtKB: O-glycosylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A1E959

  • ODAM Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ODAM Protein Expression
    REFSEQ proteins: NP_060325.3  
    ENSEMBL proteins: 
     ENSP00000379401   ENSP00000423070   ENSP00000426106   ENSP00000422100  
    Reactome Protein details: A1E959
    Human Recombinant Protein Products for ODAM: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ODAM
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ODAM
    GenScript Custom Purified and Recombinant Proteins Services for ODAM
    Novus Biologicals ODAM Protein
    Novus Biologicals ODAM Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ODAM 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0043205fibril IDA14647039

    ODAM for ontologies           About GeneDecksing



    ODAM Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ODAM
    GenScript Custom Superior Antibodies Services for ODAM
    Novus Biologicals ODAM Antibodies
    Search for Antibodies for ODAM at Abcam
    Cloud-Clone Corp. Antibodies for ODAM 
    Search ThermoFisher Antibodies for ODAM
    Search LSBio for Antibodies for ODAM 

    Assay Products for ODAM: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ODAM
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ODAM
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ODAM 
    Cloud-Clone Corp. CLIAs for ODAM


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026802 Odam

    Graphical View of Domain Structure for InterPro Entry A1E959

    ProtoNet protein and cluster: A1E959

    UniProtKB/Swiss-Prot: ODAM_HUMAN, A1E959
    Similarity: Belongs to the ODAM family


    ODAM for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ODAM_HUMAN, A1E959
    Function: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that
    results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of
    mineralization process

    Phenotypes:
         1 GenomeRNAi human phenotype for ODAM:

     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ODAM 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ODAM

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ODAM 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ODAM 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ODAM
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ODAM:
    hsa-miR-3915
    SwitchGear 3'UTR luciferase reporter plasmidODAM 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ODAM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ODAM

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ODAM
    Sirion Biotech Customized adenovirus for overexpression of ODAM

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ODAM (see all 7)
    OriGene ORF clones in mouse, rat for ODAM
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ODAM (NM_017855)
    Sino Biological Human cDNA Clone for ODAM
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ODAM
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODAM
    Sirion Biotech Customized lentivirus for stable overexpression of ODAM 
                         Customized lentivirus expression plasmids for stable overexpression of ODAM 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ODAM
    Search LifeMap BioReagents cell lines for ODAM
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODAM


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ODAM About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Packaging Of Telomere Ends
    Amyloids0.41
    2Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2        Reactome Pathways for ODAM
        Amyloids
    Disease



    ODAM for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ODAM

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/23 Interacting proteins for ODAM (A1E9593 ENSP000003794014) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    TOLLIPQ9H0E23I2D: score=2 
    APPENSP000002849814STRING: ENSP00000284981
    NPPAENSP000003656634STRING: ENSP00000365663
    PRLENSP000003021504STRING: ENSP00000302150
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031214biomineral tissue development IEA--
    GO:0042475odontogenesis of dentin-containing tooth IEP16674676

    ODAM for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ODAM

    Search CenterWatch for drugs/clinical trials and news about ODAM

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ODAM gene: 
    NM_017855.3  

    Unigene Cluster for ODAM:

    Odontogenic, ameloblast asssociated
    Hs.143811  [show with all ESTs]
    Unigene Representative Sequence: NM_017855
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396094(uc003hfc.3) ENST00000510709 ENST00000506248 ENST00000514097
    ENST00000510847
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ODAM
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ODAM:
    hsa-miR-3915
    SwitchGear 3'UTR luciferase reporter plasmidODAM 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ODAM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ODAM
    Clone
    Products:
         
    OriGene clones in human, mouse for ODAM (see all 7)
    OriGene ORF clones in mouse, rat for ODAM
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ODAM (NM_017855)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ODAM
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODAM
    Sirion Biotech Customized lentivirus for stable overexpression of ODAM 
                         Customized lentivirus expression plasmids for stable overexpression of ODAM 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ODAM
    OriGene qSTAR qPCR primer pairs in human, mouse for ODAM
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ODAM
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODAM
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODAM

    Additional mRNA sequence: 

    AK000520.1 AK098169.1 AK225547.1 BC017796.1 EF113908.1 

    5 DOTS entries:

    DT.99935634  DT.91741889  DT.435385  DT.121249300  DT.121249513 

    24/29 AceView cDNA sequences (see all 29):

    NM_017855 CD723326 CD723278 AA729875 CD724162 BX487613 BX101316 BC017796 
    AK098169 AK000520 BV205854 AI697049 AA025290 AI185064 BG194365 BV205862 
    BG218440 AA025291 BG188111 BG205136 AA385519 AA024396 BG536438 AA024531 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ODAM    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                      -                                       
    SP2:                                                                              
    SP3:                                      -                                       
    SP4:                                      -           -                           


    ECgene alternative splicing isoforms for ODAM

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ODAM expression in normal human tissues (normalized intensities)      ODAM embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGATATGTA
    ODAM Expression
    About this image


    ODAM expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial progenitor cells ( Derivation and purification of endothelial precursor...
             blood vessel   
     
     Lung (Respiratory System)
             Trachea   
     
     Oral Cavity (Gastrointestinal Tract)
             Salivary gland   
     
     Heart (Cardiovascular System)

    See ODAM Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ODAM

    SOURCE GeneReport for Unigene cluster: Hs.143811
        SABiosciences Custom PCR Arrays for ODAM
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ODAM
    OriGene qSTAR qPCR primer pairs in human, mouse for ODAM
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ODAM
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODAM
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODAM
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODAM

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ODAM gene from 1/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Odam1 , 5 odontogenic, ameloblast asssociated1, 5 76.56(n)1
    68.5(a)1
      5 (43.56 cM)5
    695921  NM_027128.21  NP_081404.21 
     878850295 


    ENSEMBL Gene Tree for ODAM (if available)
    TreeFam Gene Tree for ODAM (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/254 SNPs in ODAM are shown (see all 254)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0398134
    A colorectal cancer sample4--see VAR_0398132 E D mis40--------
    rs1165152121,2
    C,F--71060270(+) CTAAAC/TGTAAT 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1895814221,2
    --71060288(+) AATACC/TTTCTA 1 -- us2k10--------
    rs1810912521,2
    --71060310(+) GTCCTA/GCTGGT 1 -- us2k10--------
    rs728565621,2
    C,F--71060317(+) TGGTGG/TGTTTT 1 -- us2k14Minor allele frequency- T:0.09WA CSA NA 242
    rs1160863191,2
    F--71060325(+) TTTCTT/GCTTTA 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1859214101,2
    --71060362(+) ACTAAC/TGATTT 1 -- us2k10--------
    rs1890642981,2
    --71060385(+) TTTTTC/GACCAG 1 -- us2k10--------
    rs356413071,2
    C,F--71060469(+) CAAATT/GTATTA 1 -- us2k19Minor allele frequency- G:0.36NA WA CSA EA 369
    rs1814546951,2
    --71060589(+) AACACC/TTGTGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ODAM (71062213 - 71070293 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ODAM:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv879466CNV Loss21882294
    nsv517703CNV Loss19592680
    nsv829963CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ODAM
    DNA2.0 Custom Variant and Variant Library Synthesis for ODAM

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614843    OMIM disorders: --

    6 diseases for ODAM:    About MalaCards
    calcifying epithelial odontogenic tumor    ossifying fibroma    dental enamel hypoplasia    periodontitis
    gastric cancer    melanoma

    1 disease from the University of Copenhagen DISEASES database for ODAM:
    Ossifying fibroma

    ODAM for disorders           About GeneDecksing

    Genetic Association Database (GAD): ODAM

    Export disorders for ODAM gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ODAM gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with ODAM)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Calcifying epithelial odontogenic (Pindborg) tumor-associated amyloid consists of a novel human protein. (PubMed id 14647039)1, 2, 3, 9 Solomon A.... Westermark P. (2003)
    2. Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia. (PubMed id 17647262)1, 2 Moffatt P.... Nanci A. (2008)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach. (PubMed id 16674676)1, 9 Moffatt P.... Nanci A. (2006)
    5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    6. Disruption of periodontal integrity induces expressio n of apin by epithelial cell rests of Malassez. (PubMed id 20572917)1 Nishio C....Nanci A. (2010)
    7. Expanding the substantial interactome of NEMO using p rotein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (2010)
    8. Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms. (PubMed id 18472969)1 Kestler D.P....Solomon A. (2008)
    9. Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles. (PubMed id 18484335)1 Murphy C.L....Solomon A. (2008)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54959 HGNC: 26043 AceView: APIN Ensembl:ENSG00000109205 euGenes: HUgn54959
    ECgene: ODAM H-InvDB: ODAM

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ODAM Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ODAM gene:
    Search GeneIP for patents involving ODAM

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ODAM  
     OriGene qPCR primer pairs and template standards for ODAM   OriGene Protein Over-expression Lysate for ODAM  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ODAM  
     OriGene qSTAR qPCR primer pairs in human, mouse for ODAM   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ODAM   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ODAM   OriGene Custom Protein Services for ODAM  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ODAM
     QIAGEN SeqTarget long-range PCR primers for resequencing ODAM
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ODAM
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ODAM
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ODAM
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ODAM
     GenScript Custom Purified and Recombinant Proteins Services for ODAM GenScript cDNA clones with any tag delivered in your preferred vector for ODAM
     GenScript Custom Assay Services for ODAM GenScript Custom Superior Antibodies Services for ODAM
     GenScript Custom overexpressing Cell Line Services for ODAM CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ODAM promoter
     Search Chromatin IP Primers for ODAM
     RT2 qPCR Primer Assay in human, mouse, rat ODAM
     Search GNC Networks for ODAM
     SABiosciences Custom PCR Arrays for ODAM
     Search Tocris compounds for ODAM
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ODAM
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ODAM antibodies
     ODAM proteins
     ODAM lysates
     Search for Antibodies for ODAM at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ODAM
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ODAM
     Antibodies for ODAM
     ELISAs for ODAM
     CLIAs for ODAM
     Search LifeMap BioReagents cell lines for ODAM
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ODAM
     SwitchGear 3'UTR luciferase reporter plasmids for ODAM
     SwitchGear Promoter luciferase reporter plasmids for ODAM
     Search ThermoFisher Antibodies for ODAM
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ODAM
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ODAM
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ODAM
    Customized:
     lentivirus for stable overexpression of ODAM
     lentivirus expression plasmids for stable overexpression of ODAM
     adenovirus for overexpression of ODAM
     Search LSBio for Antibodies for ODAM
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ODAM gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4