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Aliases for OCM2 Gene

Aliases for OCM2 Gene

  • Oncomodulin 2 2 3
  • Parvalbumin Beta 3
  • OCMN 4
  • OCM 3
  • OM 3

External Ids for OCM2 Gene

Previous GeneCards Identifiers for OCM2 Gene

  • GC07M097454
  • GC07M097614
  • GC07M092214

Summaries for OCM2 Gene

Entrez Gene Summary for OCM2 Gene

  • This gene is similar to the oncomodulin gene, a high-affinity calcium ion-binding protein that belongs to the superfamily of calmodulin proteins, also known as the EF-hand proteins. [provided by RefSeq, Jul 2008]

GeneCards Summary for OCM2 Gene

OCM2 (Oncomodulin 2) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PVALB.

Gene Wiki entry for OCM2 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OCM2 Gene

Genomics for OCM2 Gene

Regulatory Elements for OCM2 Gene

Genomic Location for OCM2 Gene

97,984,684 bp from pter
97,991,169 bp from pter
6,486 bases
Minus strand

Genomic View for OCM2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OCM2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OCM2 Gene

Proteins for OCM2 Gene

  • Protein details for OCM2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative oncomodulin-2
    Protein Accession:
    Secondary Accessions:
    • P32930
    • Q6ISI5
    • Q75MW0

    Protein attributes for OCM2 Gene

    109 amino acids
    Molecular mass:
    12129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OCM2 Gene

Proteomics data for OCM2 Gene at MOPED

Post-translational modifications for OCM2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OCM2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OCM2 Gene

Domains & Families for OCM2 Gene

Gene Families for OCM2 Gene

Protein Domains for OCM2 Gene

Suggested Antigen Peptide Sequences for OCM2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 EF-hand domains.
  • Belongs to the parvalbumin family.
  • Contains 2 EF-hand domains.
  • Belongs to the parvalbumin family.
genes like me logo Genes that share domains with OCM2: view

Function for OCM2 Gene

Gene Ontology (GO) - Molecular Function for OCM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding NAS 8354278
genes like me logo Genes that share ontologies with OCM2: view
genes like me logo Genes that share phenotypes with OCM2: view

Animal Models for OCM2 Gene

MGI Knock Outs for OCM2:
  • Ocm tm1.1Ddsi

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OCM2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for OCM2 Gene

Localization for OCM2 Gene

Subcellular locations from

Jensen Localization Image for OCM2 Gene COMPARTMENTS Subcellular localization image for OCM2 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for OCM2 Gene

Pathways & Interactions for OCM2 Gene

SuperPathways for OCM2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for OCM2 Gene


No data available for Pathways by source and SIGNOR curated interactions for OCM2 Gene

Drugs & Compounds for OCM2 Gene

(4) Drugs for OCM2 Gene - From: NovoSeek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Nutra 0
Magnesium Nutra 0
serine Nutra 420
tyrosine Nutra 547

(4) Additional Compounds for OCM2 Gene - From: NovoSeek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with OCM2: view

Transcripts for OCM2 Gene

mRNA/cDNA for OCM2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OCM2 Gene

Oncomodulin 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OCM2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OCM2 Gene

No ASD Table

Relevant External Links for OCM2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OCM2 Gene

mRNA expression in normal human tissues for OCM2 Gene

mRNA differential expression in normal tissues according to GTEx for OCM2 Gene

This gene is overexpressed in Brain - Amygdala (x8.2).

SOURCE GeneReport for Unigene cluster for OCM2 Gene Hs.510456

genes like me logo Genes that share expression patterns with OCM2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OCM2 Gene

Orthologs for OCM2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OCM2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OCM2 35
  • 99.69 (n)
  • 100 (a)
OCM2 36
  • 100 (a)
(Mus musculus)
Mammalia Ocm 16
Ocm 36
  • 90 (a)
(Bos Taurus)
Mammalia -- 36
  • 96 (a)
(Canis familiaris)
Mammalia -- 36
  • 99 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 78 (a)
(Gallus gallus)
Aves OCM 36
  • 64 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 64 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC53003 35
(Danio rerio)
Actinopterygii pvalb9 35
  • 61.77 (n)
  • 58.72 (a)
pvalb8 36
  • 56 (a)
pvalb9 36
  • 54 (a)
Species with no ortholog for OCM2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OCM2 Gene

Gene Tree for OCM2 (if available)
Gene Tree for OCM2 (if available)

Paralogs for OCM2 Gene

Paralogs for OCM2 Gene

(9) SIMAP similar genes for OCM2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OCM2: view

Variants for OCM2 Gene

Sequence variations from dbSNP and Humsavar for OCM2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1859642 -- 97,991,975(-) CAACA(C/T)GGCAA upstream-variant-2KB
rs2894159 -- 97,986,856(+) CCGAG(A/C)ATTAT intron-variant
rs2894160 -- 97,990,407(+) AGAGA(C/T)GGGGT upstream-variant-2KB
rs3060405 -- 97,985,434(+) aaaaa(-/AGAAA)gaaag intron-variant
rs3757456 -- 97,990,156(+) CAGGA(A/C)CGTGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OCM2 Gene

Variant ID Type Subtype PubMed ID
nsv428178 CNV Gain 18775914
dgv2118e1 CNV Complex 17122850
esv32764 CNV Loss 17666407

Variation tolerance for OCM2 Gene

Residual Variation Intolerance Score: 79.92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.05; 21.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OCM2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OCM2 Gene

Disorders for OCM2 Gene

Relevant External Links for OCM2

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OCM2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OCM2 Gene

Publications for OCM2 Gene

  1. The continuing disappearance of "pure" Ca2+ buffers. (PMID: 19099190) Schwaller B. (Cell. Mol. Life Sci. 2009) 23 67
  2. Oncomodulin links inflammation to optic nerve regeneration. (PMID: 19875691) Yin Y. … Benowitz L.I. (Proc. Natl. Acad. Sci. U.S.A. 2009) 23 67
  3. Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages. (PMID: 18021771) Hauk T.G. … Fischer D. (Exp. Neurol. 2008) 23 67
  4. Rewiring the injured CNS: lessons from the optic nerve. (PMID: 17610877) Benowitz L. … Yin Y. (Exp. Neurol. 2008) 23 67
  5. Comparison of natural and recombinant forms of the major fish allergen parvalbumin from cod and carp. (PMID: 18504705) Ma Y. … Breiteneder H. (Mol Nutr Food Res 2008) 23 67

Products for OCM2 Gene

Sources for OCM2 Gene

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