Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OCLM Gene

Aliases for OCLM Gene

  • Oculomedin 2 3
  • TISR 3 4
  • Trabecular Meshwork Inducible Stretch Response Protein 3
  • Trabecular Meshwork-Inducible Stretch Response Protein 4

External Ids for OCLM Gene

Previous GeneCards Identifiers for OCLM Gene

  • GC01P183895
  • GC01P181797
  • GC01P182889
  • GC01U900851
  • GC01P183608
  • GC01P183101
  • GC01P184636
  • GC01P186369

Summaries for OCLM Gene

Entrez Gene Summary for OCLM Gene

  • The protein encoded by this gene is induced by cyclic mechanical stretching in trabecular cells of the eye and it is also expressed in retina. This protein may play a role in trabecular meshwork function and the development of glaucoma. [provided by RefSeq, Jul 2008]

GeneCards Summary for OCLM Gene

OCLM (Oculomedin) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OCLM Gene

Genomics for OCLM Gene

Regulatory Elements for OCLM Gene

Genomic Location for OCLM Gene

Start:
186,400,572 bp from pter
End:
186,401,455 bp from pter
Size:
884 bases
Orientation:
Plus strand

Genomic View for OCLM Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OCLM Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OCLM Gene

Proteins for OCLM Gene

  • Protein details for OCLM Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y5M6-TISR_HUMAN
    Recommended name:
    Oculomedin
    Protein Accession:
    Q9Y5M6
    Secondary Accessions:
    • Q4G0F9

    Protein attributes for OCLM Gene

    Size:
    44 amino acids
    Molecular mass:
    5321 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OCLM Gene

Proteomics data for OCLM Gene at MOPED

Post-translational modifications for OCLM Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OCLM Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OCLM Gene

Domains for OCLM Gene

Protein Domains for OCLM Gene

ProtoNet:

Suggested Antigen Peptide Sequences for OCLM Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OCLM: view

No data available for Gene Families and UniProtKB/Swiss-Prot for OCLM Gene

Function for OCLM Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OCLM Gene

Localization for OCLM Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for OCLM Gene

Pathways for OCLM Gene

SuperPathways for OCLM Gene

No Data Available

Interacting Proteins for OCLM Gene

Gene Ontology (GO) - Biological Process for OCLM Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007601 visual perception TAS 10362512
genes like me logo Genes that share ontologies with OCLM: view

No data available for Pathways by source for OCLM Gene

Transcripts for OCLM Gene

mRNA/cDNA for OCLM Gene

(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OCLM Gene

Oculomedin:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OCLM

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OCLM Gene

No ASD Table

Relevant External Links for OCLM Gene

GeneLoc Exon Structure for
OCLM
ECgene alternative splicing isoforms for
OCLM

Expression for OCLM Gene

mRNA expression in normal human tissues for OCLM Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OCLM Gene

SOURCE GeneReport for Unigene cluster for OCLM Gene Hs.679230

mRNA Expression by UniProt/SwissProt for OCLM Gene

Q9Y5M6-TISR_HUMAN
Tissue specificity: Expressed in eye trabeculum; also expressed in retina
genes like me logo Genes that share expressions with OCLM: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for OCLM Gene

Orthologs for OCLM Gene

Evolution for OCLM Gene

ENSEMBL:
Gene Tree for OCLM (if available)
TreeFam:
Gene Tree for OCLM (if available)

No data available for Orthologs for OCLM Gene

Paralogs for OCLM Gene

No data available for Paralogs for OCLM Gene

Variants for OCLM Gene

Structural Variations from Database of Genomic Variants (DGV) for OCLM Gene

Variant ID Type Subtype PubMed ID
nsv872589 CNV Loss 21882294

Relevant External Links for OCLM Gene

HapMap Linkage Disequilibrium report
OCLM

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for OCLM Gene

Disorders for OCLM Gene

No disorders were found for OCLM Gene.

No data available for UniProtKB/Swiss-Prot for OCLM Gene

Publications for OCLM Gene

  1. A novel gene (oculomedin) induced by mechanical stretching in human trabecular cells of the eye. (PMID: 10362512) Sato Y. … Ohtsuki H. (Biochem. Biophys. Res. Commun. 1999) 2 3 4 23
  2. Absence of trabecular meshwork-inducible stretch response (TISR)/oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients. (PMID: 11129344) Leung Y.F. … Pang C.P. (Hum. Genet. 2000) 3 23
  3. Protein expression, genomic structure, and polymorphisms of oculomedin. (PMID: 12868032) Fujiwara N. … Ohtsuki H. (Ophthalmic Genet. 2003) 3 23
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OCLM Gene

Sources for OCLM Gene

Back to Top

Content