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Aliases for OCIAD2 Gene

Aliases for OCIAD2 Gene

  • OCIA Domain Containing 2 2 3
  • Ovarian Carcinoma Immunoreactive Antigen-Like Protein 4

External Ids for OCIAD2 Gene

Summaries for OCIAD2 Gene

GeneCards Summary for OCIAD2 Gene

OCIAD2 (OCIA Domain Containing 2) is a Protein Coding gene. Diseases associated with OCIAD2 include ovarian mucinous neoplasm. An important paralog of this gene is OCIAD1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OCIAD2 Gene

Genomics for OCIAD2 Gene

Genomic Location for OCIAD2 Gene

Start:
48,885,019 bp from pter
End:
48,906,937 bp from pter
Size:
21,919 bases
Orientation:
Minus strand

Genomic View for OCIAD2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OCIAD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OCIAD2 Gene

Regulatory Elements for OCIAD2 Gene

Proteins for OCIAD2 Gene

  • Protein details for OCIAD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q56VL3-OCAD2_HUMAN
    Recommended name:
    OCIA domain-containing protein 2
    Protein Accession:
    Q56VL3
    Secondary Accessions:
    • B4DPE7
    • Q8N544

    Protein attributes for OCIAD2 Gene

    Size:
    154 amino acids
    Molecular mass:
    16954 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for OCIAD2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OCIAD2 Gene

Proteomics data for OCIAD2 Gene at MOPED

Post-translational modifications for OCIAD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OCIAD2 Gene

No data available for DME Specific Peptides for OCIAD2 Gene

Domains for OCIAD2 Gene

Protein Domains for OCIAD2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for OCIAD2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q56VL3

UniProtKB/Swiss-Prot:

OCAD2_HUMAN
Domain:
  • Contains 1 OCIA domain.:
    • Q56VL3
genes like me logo Genes that share domains with OCIAD2: view

No data available for Gene Families for OCIAD2 Gene

Function for OCIAD2 Gene

miRNA for OCIAD2 Gene

miRTarBase miRNAs that target OCIAD2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OCIAD2 Gene

Localization for OCIAD2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OCIAD2 Gene

Endosome.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OCIAD2 Gene COMPARTMENTS Subcellular localization image for OCIAD2 gene
Compartment Confidence
endosome 4
mitochondrion 3
plasma membrane 3
extracellular 2
peroxisome 2
cytosol 1
golgi apparatus 1
nucleus 1

Gene Ontology (GO) - Cellular Components for OCIAD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane IEA --
GO:0005768 endosome IEA --
genes like me logo Genes that share ontologies with OCIAD2: view

Pathways for OCIAD2 Gene

SuperPathways for OCIAD2 Gene

No Data Available

Interacting Proteins for OCIAD2 Gene

Gene Ontology (GO) - Biological Process for OCIAD2 Gene

None

No data available for Pathways by source for OCIAD2 Gene

Transcripts for OCIAD2 Gene

Unigene Clusters for OCIAD2 Gene

OCIA domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OCIAD2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7
SP1: - - -
SP2:
SP3:

Relevant External Links for OCIAD2 Gene

GeneLoc Exon Structure for
OCIAD2
ECgene alternative splicing isoforms for
OCIAD2

Expression for OCIAD2 Gene

mRNA expression in normal human tissues for OCIAD2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OCIAD2 Gene

This gene is overexpressed in Kidney - Cortex (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for OCIAD2 Gene

SOURCE GeneReport for Unigene cluster for OCIAD2 Gene Hs.95835

genes like me logo Genes that share expressions with OCIAD2: view

No data available for mRNA Expression by UniProt/SwissProt for OCIAD2 Gene

Orthologs for OCIAD2 Gene

This gene was present in the common ancestor of animals.

Orthologs for OCIAD2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OCIAD2 35
  • 99.35 (n)
  • 98.05 (a)
OCIAD2 36
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OCIAD2 35
  • 88.74 (n)
  • 85.06 (a)
OCIAD2 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OCIAD2 35
  • 87.23 (n)
  • 85.06 (a)
OCIAD2 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ociad2 35
  • 85.71 (n)
  • 84.42 (a)
Ociad2 16
Ociad2 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OCIAD2 36
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ociad2 35
  • 85.28 (n)
  • 84.42 (a)
lizard
(Anolis carolinensis)
Reptilia OCIAD2 36
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ociad2 35
  • 59.9 (n)
  • 55.8 (a)
zebrafish
(Danio rerio)
Actinopterygii ociad2 35
  • 54.46 (n)
  • 49.11 (a)
ociad2 36
  • 36 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta asrij 36
  • 15 (a)
OneToMany
Species with no ortholog for OCIAD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OCIAD2 Gene

ENSEMBL:
Gene Tree for OCIAD2 (if available)
TreeFam:
Gene Tree for OCIAD2 (if available)

Paralogs for OCIAD2 Gene

Paralogs for OCIAD2 Gene

Selected SIMAP similar genes for OCIAD2 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for OCIAD2 Gene

genes like me logo Genes that share paralogs with OCIAD2: view

Variants for OCIAD2 Gene

Sequence variations from dbSNP and Humsavar for OCIAD2 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs1840632 -- 48,907,810(-) attag(C/G)taagc upstream-variant-2KB
rs2249306 -- 48,902,818(+) catgg(C/T)ggcag intron-variant
rs2289065 -- 48,892,964(-) ACCAG(C/T)GTTGA intron-variant
rs2290516 -- 48,906,337(-) CCCCC(A/G)CCCCC intron-variant
rs2354948 -- 48,905,818(+) GGTCA(A/G)AGAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OCIAD2 Gene

Variant ID Type Subtype PubMed ID
nsv879010 CNV Loss 21882294

Relevant External Links for OCIAD2 Gene

HapMap Linkage Disequilibrium report
OCIAD2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OCIAD2 Gene

Disorders for OCIAD2 Gene

(1) MalaCards Diseases for OCIAD2 Gene

Search for OCIAD2 Gene in MalaCards »

(1) University of Copenhagen DISEASES for OCIAD2 Gene

genes like me logo Genes that share disorders with OCIAD2: view

No data available for UniProtKB/Swiss-Prot for OCIAD2 Gene

Publications for OCIAD2 Gene

  1. OCIA domain containing 2 is highly expressed in adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component and is associated with better prognosis. (PMID: 17054434) Ishiyama T. … Noguchi M. (Cancer Sci. 2007) 2 3 23
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for OCIAD2 Gene

Sources for OCIAD2 Gene

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