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Aliases for OCIAD1 Gene

Aliases for OCIAD1 Gene

  • OCIA Domain Containing 1 2 3
  • Ovarian Carcinoma Immunoreactive Antigen 3 4
  • OCIA 3 4
  • TPA018 3
  • ASRIJ 3

External Ids for OCIAD1 Gene

Previous GeneCards Identifiers for OCIAD1 Gene

  • GC04P048674
  • GC04P048527
  • GC04P048152

Summaries for OCIAD1 Gene

GeneCards Summary for OCIAD1 Gene

OCIAD1 (OCIA Domain Containing 1) is a Protein Coding gene. Diseases associated with OCIAD1 include ovarian mucinous neoplasm. An important paralog of this gene is OCIAD2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OCIAD1 Gene

Genomics for OCIAD1 Gene

Regulatory Elements for OCIAD1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for OCIAD1 Gene

Chromosome:
4
Start:
48,805,212 bp from pter
End:
48,861,817 bp from pter
Size:
56,606 bases
Orientation:
Plus strand

Genomic View for OCIAD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OCIAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OCIAD1 Gene

Proteins for OCIAD1 Gene

  • Protein details for OCIAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX40-OCAD1_HUMAN
    Recommended name:
    OCIA domain-containing protein 1
    Protein Accession:
    Q9NX40
    Secondary Accessions:
    • C9K030
    • G8JLN7
    • Q9BZE8

    Protein attributes for OCIAD1 Gene

    Size:
    245 amino acids
    Molecular mass:
    27626 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for OCIAD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OCIAD1 Gene

Proteomics data for OCIAD1 Gene at MOPED

Post-translational modifications for OCIAD1 Gene

  • Ubiquitination at Lys 72
  • Modification sites at PhosphoSitePlus

Antibody Products

No data available for DME Specific Peptides for OCIAD1 Gene

Domains & Families for OCIAD1 Gene

Protein Domains for OCIAD1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for OCIAD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NX40

UniProtKB/Swiss-Prot:

OCAD1_HUMAN :
  • Contains 1 OCIA domain.
  • Belongs to the OCIAD1 family.
Domain:
  • Contains 1 OCIA domain.
Family:
  • Belongs to the OCIAD1 family.
genes like me logo Genes that share domains with OCIAD1: view

No data available for Gene Families for OCIAD1 Gene

Function for OCIAD1 Gene

Gene Ontology (GO) - Molecular Function for OCIAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with OCIAD1: view

Phenotypes for OCIAD1 Gene

genes like me logo Genes that share phenotypes with OCIAD1: view

Animal Model Products

miRNA for OCIAD1 Gene

miRTarBase miRNAs that target OCIAD1

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OCIAD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for OCIAD1 Gene

Localization for OCIAD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OCIAD1 Gene

Endosome.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OCIAD1 Gene COMPARTMENTS Subcellular localization image for OCIAD1 gene
Compartment Confidence
endosome 3
mitochondrion 2

Gene Ontology (GO) - Cellular Components for OCIAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0005768 endosome IEA --
GO:0016020 membrane IDA 19946888
genes like me logo Genes that share ontologies with OCIAD1: view

Pathways & Interactions for OCIAD1 Gene

SuperPathways for OCIAD1 Gene

No Data Available

Interacting Proteins for OCIAD1 Gene

Gene Ontology (GO) - Biological Process for OCIAD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OCIAD1 Gene

Drugs & Compounds for OCIAD1 Gene

No Compound Related Data Available

Transcripts for OCIAD1 Gene

Unigene Clusters for OCIAD1 Gene

OCIA domain containing 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OCIAD1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OCIAD1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^
SP1: - - - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - - - -
SP4: - - - - - - - - -
SP5: - - - -
SP6: - - - -
SP7: - - - -
SP8: - - - - - - - - - - - - -
SP9: - - - - -
SP10: - - - - - - - - - - -
SP11: - - - -
SP12: - -
SP13: - - - - - - - - - - - -
SP14: - - - - -
SP15: - - - - -
SP16:
SP17: -
SP18: -

ExUns: 13a · 13b · 13c · 13d ^ 14a · 14b · 14c · 14d
SP1:
SP2: - - - -
SP3: - - - -
SP4:
SP5:
SP6: - - - -
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: - - - -
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for OCIAD1 Gene

GeneLoc Exon Structure for
OCIAD1
ECgene alternative splicing isoforms for
OCIAD1

Expression for OCIAD1 Gene

mRNA expression in normal human tissues for OCIAD1 Gene

Protein differential expression in normal tissues from HIPED for OCIAD1 Gene

This gene is overexpressed in Nasal epithelium (36.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for OCIAD1 Gene



SOURCE GeneReport for Unigene cluster for OCIAD1 Gene Hs.518750

mRNA Expression by UniProt/SwissProt for OCIAD1 Gene

Q9NX40-OCAD1_HUMAN
Tissue specificity: Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
genes like me logo Genes that share expression patterns with OCIAD1: view

Protein tissue co-expression partners for OCIAD1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for OCIAD1 Gene

Orthologs for OCIAD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OCIAD1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OCIAD1 35
  • 93.74 (n)
  • 92.24 (a)
OCIAD1 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OCIAD1 35
  • 94.01 (n)
  • 93.47 (a)
OCIAD1 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ociad1 35
  • 86.94 (n)
  • 86.12 (a)
Ociad1 16
Ociad1 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia OCIAD1 35
  • 99.59 (n)
  • 99.59 (a)
OCIAD1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ociad1 35
  • 87.62 (n)
  • 86.12 (a)
oppossum
(Monodelphis domestica)
Mammalia OCIAD1 36
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OCIAD1 36
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves OCIAD1 35
  • 61.65 (n)
  • 51.88 (a)
OCIAD1 36
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia OCIAD1 36
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ociad1 35
  • 60.79 (n)
  • 52.42 (a)
Str.15349 35
zebrafish
(Danio rerio)
Actinopterygii ociad1 35
  • 56.56 (n)
  • 52.49 (a)
ociad1 36
  • 42 (a)
ManyToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007618 35
  • 39.7 (n)
  • 31.36 (a)
fruit fly
(Drosophila melanogaster)
Insecta asrij 35
  • 41.93 (n)
  • 36.2 (a)
asrij 36
  • 28 (a)
OneToMany
Species with no ortholog for OCIAD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OCIAD1 Gene

ENSEMBL:
Gene Tree for OCIAD1 (if available)
TreeFam:
Gene Tree for OCIAD1 (if available)

Paralogs for OCIAD1 Gene

Paralogs for OCIAD1 Gene

genes like me logo Genes that share paralogs with OCIAD1: view

Variants for OCIAD1 Gene

Structural Variations from Database of Genomic Variants (DGV) for OCIAD1 Gene

Variant ID Type Subtype PubMed ID
nsv879010 CNV Loss 21882294

Variation tolerance for OCIAD1 Gene

Residual Variation Intolerance Score: 38.37% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.92; 19.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OCIAD1 Gene

HapMap Linkage Disequilibrium report
OCIAD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for OCIAD1 Gene

Disorders for OCIAD1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for OCIAD1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
ovarian mucinous neoplasm
  • malignant ovarian mucinous neoplasm
- elite association

Relevant External Links for OCIAD1

Genetic Association Database (GAD)
OCIAD1
Human Genome Epidemiology (HuGE) Navigator
OCIAD1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OCIAD1
genes like me logo Genes that share disorders with OCIAD1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OCIAD1 Gene

Publications for OCIAD1 Gene

  1. Ovarian cancer immuno-reactive antigen domain containing 1 (OCIAD1), a key player in ovarian cancer cell adhesion. (PMID: 18328549) Sengupta S. … Ganapathi R. (Gynecol. Oncol. 2008) 2 67
  2. Molecular cloning of a novel human gene on chromosome 4p11 by immunoscreening of an ovarian carcinoma cDNA library. (PMID: 11162530) Luo L.Y. … Diamandis E.P. (Biochem. Biophys. Res. Commun. 2001) 2 67
  3. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J. … Shi Y. (Genes Dev. 2015) 67
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 67

Products for OCIAD1 Gene

Sources for OCIAD1 Gene

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