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Aliases for OCEL1 Gene

Aliases for OCEL1 Gene

  • Occludin/ELL Domain Containing 1 2 3 5
  • Occludin/ELL Domain-Containing Protein 1 3
  • FWP009 3
  • S863-9 3

External Ids for OCEL1 Gene

Previous GeneCards Identifiers for OCEL1 Gene

  • GC19P017201
  • GC19P017337
  • GC19P016904
  • GC19P017289
  • GC19P017685
  • GC19P017711

Summaries for OCEL1 Gene

GeneCards Summary for OCEL1 Gene

OCEL1 (Occludin/ELL Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is MARVELD2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OCEL1 Gene

Genomics for OCEL1 Gene

Regulatory Elements for OCEL1 Gene

Enhancers for OCEL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around OCEL1 on UCSC Golden Path with GeneCards custom track

Promoters for OCEL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for OCEL1 Gene

17,226,204 bp from pter
17,229,219 bp from pter
3,016 bases
Plus strand

Genomic View for OCEL1 Gene

Genes around OCEL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OCEL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OCEL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OCEL1 Gene

Proteins for OCEL1 Gene

  • Protein details for OCEL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Occludin/ELL domain-containing protein 1
    Protein Accession:

    Protein attributes for OCEL1 Gene

    264 amino acids
    Molecular mass:
    29404 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OCEL1 Gene

Post-translational modifications for OCEL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for OCEL1 Gene

Domains & Families for OCEL1 Gene

Protein Domains for OCEL1 Gene

Suggested Antigen Peptide Sequences for OCEL1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ELL/occludin family.
  • Belongs to the ELL/occludin family.
genes like me logo Genes that share domains with OCEL1: view

No data available for Gene Families for OCEL1 Gene

Function for OCEL1 Gene

genes like me logo Genes that share phenotypes with OCEL1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OCEL1 Gene

Localization for OCEL1 Gene

Subcellular locations from

Jensen Localization Image for OCEL1 Gene COMPARTMENTS Subcellular localization image for OCEL1 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for OCEL1 Gene

Pathways & Interactions for OCEL1 Gene

SuperPathways for OCEL1 Gene

No Data Available

Interacting Proteins for OCEL1 Gene

Gene Ontology (GO) - Biological Process for OCEL1 Gene


No data available for Pathways by source and SIGNOR curated interactions for OCEL1 Gene

Drugs & Compounds for OCEL1 Gene

No Compound Related Data Available

Transcripts for OCEL1 Gene

Unigene Clusters for OCEL1 Gene

Occludin/ELL domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OCEL1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c
SP1: - - - -
SP2: - - - - - -
SP3: -
SP4: - -
SP5: -
SP6: - -
SP7: - -
SP9: - - - -

Relevant External Links for OCEL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OCEL1 Gene

mRNA expression in normal human tissues for OCEL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for OCEL1 Gene

This gene is overexpressed in Neutrophil (39.7), Blymphocyte (22.0), and Tlymphocyte (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OCEL1 Gene

Protein tissue co-expression partners for OCEL1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OCEL1 Gene:


SOURCE GeneReport for Unigene cluster for OCEL1 Gene:

genes like me logo Genes that share expression patterns with OCEL1: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OCEL1 Gene

Orthologs for OCEL1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OCEL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OCEL1 34
  • 84.47 (n)
  • 78.64 (a)
-- 35
  • 74 (a)
-- 35
  • 79 (a)
(Canis familiaris)
Mammalia OCEL1 34
  • 81.2 (n)
  • 73.57 (a)
OCEL1 35
  • 56 (a)
(Mus musculus)
Mammalia Ocel1 34
  • 76.42 (n)
  • 70.12 (a)
Ocel1 16
Ocel1 35
  • 59 (a)
(Pan troglodytes)
Mammalia OCEL1 34
  • 99.49 (n)
  • 99.24 (a)
OCEL1 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Ocel1 34
  • 75.7 (n)
  • 70.48 (a)
(Monodelphis domestica)
Mammalia OCEL1 35
  • 34 (a)
(Gallus gallus)
Aves -- 35
  • 8 (a)
(Danio rerio)
Actinopterygii si:dkey-208k22.6 35
  • 12 (a)
fruit fly
(Drosophila melanogaster)
Insecta Su(Tpl) 35
  • 5 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1855 35
  • 13 (a)
Species where no ortholog for OCEL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OCEL1 Gene

Gene Tree for OCEL1 (if available)
Gene Tree for OCEL1 (if available)

Paralogs for OCEL1 Gene

Paralogs for OCEL1 Gene

genes like me logo Genes that share paralogs with OCEL1: view

Variants for OCEL1 Gene

Sequence variations from dbSNP and Humsavar for OCEL1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10425488 - 17,226,748(+) GACCC(G/T)CCCAT reference, missense, utr-variant-5-prime
rs891203 - 17,227,073(-) TCTTT(C/G)CCTTG reference, missense
rs10424828 -- 17,226,472(+) GCGGC(A/G)ACGTC intron-variant
rs3745163 -- 17,226,746(+) AGGAC(A/C)CGCCC reference, synonymous-codon, utr-variant-5-prime
rs3745164 -- 17,226,924(+) TTTAG(C/T)CCCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OCEL1 Gene

Variant ID Type Subtype PubMed ID
nsv458373 CNV loss 19166990
nsv470129 CNV loss 18288195
nsv578739 CNV loss 21841781
nsv828469 CNV loss 20364138

Variation tolerance for OCEL1 Gene

Residual Variation Intolerance Score: 93.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.53; 82.32% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OCEL1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OCEL1 Gene

Disorders for OCEL1 Gene

Relevant External Links for OCEL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OCEL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OCEL1 Gene

Publications for OCEL1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  4. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3 65
  5. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3 65

Products for OCEL1 Gene

Sources for OCEL1 Gene

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