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Aliases &
Descriptions
for OC90
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| Oc90 3 | | PLA2L 2, 3, 5 |
| | | Descriptions |
|---|
| Phospholipase A2 homolog 3 | | otoconin 90 2 | | phospholipase A2-like 2 |
|
| |
Search outside databases for aliases for OC90 genePrevious GC identifers: GC08U990050 GC08M133069 GC08M132708 GC08M132993 |
Summaries
for OC90(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: OC90_HUMAN, Q02509Function: It is unlikely that this protein has phospholipase A2 activity |
Genomic Location
for OC90
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.22 Ensembl cytogenetic band: 8q24.22 HGNC cytogenetic band: 8q24OC90 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M133105:
(about GC identifiers)
Start:
|
133,105,667 bp from pter |
End:
|
133,167,084 bp from pter |
Size:
|
61,418 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000008.9 NT_008046.15
| Proteins
for OC90
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: OC90_HUMAN, Q02509 (See
protein sequence)Recommended Name: Otoconin-90 precursor Size: 493 amino acids; 53454 Da
Subunit: Interacts with OTOL1 (By similarity)
Subcellular location: Secreted (By similarity)REFSEQ proteins: NP_001073868.2
ENSEMBL proteins: ENSP00000262283 ENSP00000254627
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | | GO:0005578 | proteinaceous extracellular matrix |
IEA | -- |
About this table
Antibodies for OC90:
Assays for OC90: | Protein
Domains/
Families
for OC90(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q02509
ProtoNet protein and cluster: Q02509 1 Blocks protein family: IPB001211 Phospholipase A2
UniProtKB/Swiss-Prot: OC90_HUMAN, Q02509Domain: Consists of 3 PA2-type domainsSimilarity: Belongs to the phospholipase A2 family | Gene Function
for OC90
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
 Applied Biosystems Silencer® siRNAs for OC90
 Sigma-Aldrich siRNA for OC90
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001080399
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001080399
untagged cDNA clone in CMV expression vector: NM_001080399
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001080399
UniProtKB/Swiss-Prot: OC90_HUMAN, Q02509Function: It is unlikely that this protein has phospholipase A2 activityGenatlas biochemistry entry for OC90:atoconin 90,phospholipase-A2 like secreted protein,linked to HHLA1 by intergenic splicing,homolog
to a murine protein expressed in fetal inner ear2 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Oc90):
3 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0004623 | phospholipase A2 activity |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
About this table | Pathways & Interactions
for OC90
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/7 Sigma-Aldrich "Your Favorite Gene" Pathways for OC90 (Your Favorite Gene powered by Ingenuity) (see all 7
)
--3 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
IEA | -- | | GO:0008150 | biological_process |
ND | -- | | GO:0016042 | lipid catabolic process |
IEA | -- |
About this table
|
Drugs & Compounds
for OC90(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for OC90
|
Transcripts
for OC90(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Sigma-Aldrich siRNA for OC90
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001080399 REFSEQ mRNAs for OC90 gene: NM_001080399.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001080399
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001080399
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001080399
untagged cDNA clone in CMV expression vector: NM_001080399
Additional cDNA sequence: AK297911.1
 highest scoring ESTs for OC90:DV080115 NM_001080399 Unigene Cluster for OC90: Otoconin 90 Hs.653174 [show with all ESTs]Unigene Representative Sequence: NM_001080399
GeneLoc Exon Structure
2 Ensembl transcripts including schematic representations: ENST00000262283
ENST00000254627
|
Expression
for OC90
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| OC90 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for OC90
1 Data from GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GTACCTCCAT
SOURCE GeneReport for Unigene cluster: Hs.653174
|
Orthologs
for OC90
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for OC90 gene from 5/6 species (see all 6
)
About this table Species with no ortholog for OC90
ENSEMBL Gene Tree for OC90 | Paralogs
for OC90(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for OC90 gene
- PLA2G2E2 PLA2G1B2 PLA2G102
|
SNPs/Variants
for OC90(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for OC90 (up to first 250kb)
|
Disorders & Mutations
for OC90
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 601658
|
Medical News
for OC90(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for OC90 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for OC90 gene: |
Search for OC90
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OC90
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing OC90
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OC90(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for OC90(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for OC90:
 | |
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| | |  | Search Tocris compounds for OC90 |
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