OBSL1 Gene
protein-coding GIFtS: 51
GCID: GC02M220415
|
|
obscurin-like 1
| |
Aliases
for OBSL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Obscurin-Like 11 2 | | KIAA06571 3 5 | | Obscurin-Like Protein 12 | | 3M25 | | EC 1.1.1.268 | | EC 2.7.4.68 |
Export aliases for OBSL1 gene to outside databasesPrevious GC identifers: GC02M220242 GC02M220124 GC02M212268 |
Summaries
for OBSL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OBSL1:
Cytoskeletal adaptor proteins function in linking the internal cytoskeleton of cells to the cell membrane. This geneencodes a cytoskeletal adaptor protein, which is a member of the Unc-89/obscurin family. The protein contains multipleN- and C-terminal immunoglobulin (Ig)-like domains and a central fibronectin type 3 domain. Mutations in this genecause 3M syndrome type 2. Alternatively spliced transcript variants encoding different isoforms have been found inthis gene. (provided by RefSeq, Mar 2010)
Gene Wiki entry for OBSL1
|
Genomic Views
for OBSL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OBSL1 gene promoter:
GR Pax-5 GATA-6 p53 GR-beta GR-alpha GATA-2 E47 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for OBSL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OBSL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q35 Ensembl cytogenetic band: 2q35 HGNC cytogenetic band: 2q35OBSL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M220415: view genomic region
(about GC identifiers)
Start:
|
220,415,450 bp from pter |
End:
|
220,436,581 bp from pter |
Size:
|
21,132 bases |
Orientation:
|
minus strand |
|
Proteins
for OBSL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: OBSL1_HUMAN, O75147 (See
protein sequence)Recommended Name: Obscurin-like protein 1 precursor Size: 1896 amino acids; 206947 Da
Subunit: Interacts with CCDC8 and CUL7
Sequence caution: Sequence=AAH07201.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
6/9 PDB 3D structures from  and Proteopedia  for OBSL1 (see all 9):2CPC (3D)
2E6P (3D)
2E6Q (3D)
2LU7 (3D)
2LVC (3D)
2WP3 (3D)
Secondary accessions: A4KVA5 Q96IW3Alternative splicing: 3 isoforms: O75147-3 O75147-2 O75147-1 Explore the universe of human proteins at neXtProt for OBSL1: NX_O75147
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75147
3 DME Specific Peptides for OBSL1 (O75147)
OBSL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001166879.1 NP_001166902.1 NP_056126.1
ENSEMBL proteins: ENSP00000385636 ENSP00000362983 ENSP00000403665 ENSP00000362980 ENSP00000289656 ENSP00000265317 ENSP00000265318
Human Recombinant Protein Products for OBSL1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
OBSL1 for ontologies About GeneDecksing
OBSL1 Antibody Products:
Assay Products for OBSL1: |
Protein
Domains /
Families
for OBSL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OBSL1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry O75147ProtoNet protein and cluster: O75147 1 Blocks protein family: IPB013098 Immunoglobulin I-set
UniProtKB/Swiss-Prot: OBSL1_HUMAN, O75147Similarity: Contains 1 fibronectin type-III domainSimilarity: Contains 14 Ig-like (immunoglobulin-like) domains |
Function
for OBSL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Enzyme Numbers (IUBMB): EC 2.7.4.62 EC 1.1.1.262
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008093 | cytoskeletal adaptor activity |
NAS | 17289344 |
OBSL1 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): OBSL1 (NM_015311) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OBSL1 |
|
Pathways & Interactions
for OBSL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OBSL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/10 Interacting proteins for OBSL1 (O751472, 3 ENSP000003856364) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
OBSL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for OBSL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for OBSL1
Search CenterWatch for drugs/clinical trials and news about OBSL1
|
Transcripts
for OBSL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OBSL1 gene (3 alternative transcripts): NM_001173408.1 NM_001173431.1 NM_015311.2 Unigene Cluster for OBSL1: Obscurin-like 1 Hs.526594 [show with all ESTs]Unigene Representative Sequence: NM_01531114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000462534 ENST00000489804 ENST00000465149 ENST00000404537(uc010fwk.3 uc010fwl.2)
ENST00000373876 ENST00000456147 ENST00000472388 ENST00000373873(uc002vmi.3)
ENST00000289656 ENST00000462385 ENST00000465589 ENST00000491370 ENST00000265317(uc002vmh.1 uc010zli.1)
ENST00000265318
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 (see all 3)
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variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): OBSL1 (NM_015311) | | | DNA2.0 Custom Codon Optimized Gene
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Additional cDNA sequence: AF035292.1 AK023854.1 AK025946.1 AK092118.1 AK299261.1 BC007201.1 BC061909.1 EF063638.1 23 DOTS entries: DT.99963032 DT.216748 DT.405896 DT.110924 DT.91750101 DT.97846331 DT.429047 DT.95312530 DT.87015490 DT.97846329 DT.95141774 DT.95155791 DT.100704378 DT.75119264 DT.91811417 DT.100791274 DT.120947791 DT.40122355 DT.91911246 DT.101961551 DT.120947777 DT.40258328 DT.40267058 24/323 AceView cDNA sequences (see all 323): T16558 AA878785 BX381924 AI791877 AL079501 AA988591 AI820653 AI219706 CA413436 AL041603 F10891 AI240918 BM014515 F03653 AW874491 AU119815 AI905001 F05060 F13292 AI288384 AI241134 N57473 BQ181841 CA414466
GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for OBSL1 (see all 17) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | · | 17c | · | 17d | · | 17e | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | |
ECgene alternative splicing isoforms for OBSL1
|
Expression
for OBSL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OBSL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See OBSL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OBSL1
SOURCE GeneReport for Unigene cluster: Hs.526594
UniProtKB/Swiss-Prot: OBSL1_HUMAN, O75147Tissue specificity: Widely expressed, with predominant levels found in the heart
SABiosciences Custom PCR Arrays for OBSL1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OBSL1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OBSL1 |
Orthologs
for OBSL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for OBSL1 gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for OBSL1 (if available)
TreeFam Gene Tree for OBSL1 (if available) |
Paralogs
for OBSL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for OBSL1 gene
- STK17B2 DAPK22 MYLK22 TTN2 MYLK32 STK17A2 OBSCN2 DAPK32
- SPEG2 MYLK42 DAPK12 MYLK2
4 SIMAP similar genes for OBSL1 using alignment to 8 protein entries: OBSL1_HUMAN (see all proteins):KIAA0992 PTPRS TTN OBSCN
OBSL1 for paralogs About GeneDecksing
|
Genomic Variants
for OBSL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OBSL1 (220415450 - 220436581 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for OBSL1: --
Human Gene Mutation Database (HGMD): OBSL1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OBSL1 |
|
Disorders
/ Diseases
for OBSL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OBSL1 for disorders About GeneDecksing
OMIM gene information: 610991
OMIM disorders: 612921
UniProtKB/Swiss-Prot: OBSL1_HUMAN, O75147
Defects in OBSL1 are the cause of 3M syndrome type 2 (3M2) [MIM:612921]. An autosomal recessive disordercharacterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, andnormal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebralbodies
7  diseases for OBSL1: About MalaCards3-m syndrome mulibrey nanism dubowitz syndrome hydrocele
growth disorders myopathy pharyngitis
2 diseases from the University of Copenhagen DISEASES database for OBSL1:Dubowitz Syndrome Hydrocele Export disorders for OBSL1 gene to outside databases
|
Publications
for OBSL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OBSL1 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with OBSL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
- Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin. (PubMed id 17289344)1, 2, 9 Geisler S.B.... Russell M.W. (2007)
- Exome sequencing identifies CCDC8 mutations in 3-M syndrome, Suggesting that CCDC8 Contributes in a Pathway with CUL7 and OBSL1 to Control Human Growth. (PubMed id 21737058)1, 2 Hanson D.... Black G.C. (2011)
- The primordial growth disorder 3-M syndrome connects ubiquitination to the cytoskeletal adaptor OBSL1. (PubMed id 19481195)1, 2 Hanson D.... Clayton P.E. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies. (PubMed id 18477606)1, 9 Fukuzawa A....Gautel M. (2008)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechani sm regulates Golgi morphology and dendrite patterning. (PubMed id 21572988)1 Litterman N....Bonni A. (2011)
- The genetics of 3-m syndrome: unravelling a potential new regulatory growth pathway. (PubMed id 22156540)1 Hanson D....Clayton P.E. (2011)
|
External Searches for OBSL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OBSL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OBSL1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing OBSL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OBSL1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for OBSL1 gene:
Search GeneIP for patents involving OBSL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OBSL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for OBSL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OBSL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OBSL1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OBSL1 | | OriGene 3'-UTR Clone for OBSL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OBSL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OBSL1 | | OriGene Custom Protein Services for OBSL1 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OBSL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OBSL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OBSL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OBSL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OBSL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OBSL1 |
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| | | | Search Tocris compounds for OBSL1 |
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 | | | OBSL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OBSL1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for OBSL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OBSL1 |
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