Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OBSCN-AS1 Gene

Subcategory (RNA class) for OBSCN-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for OBSCN-AS1 Gene

  • OBSCN Antisense RNA 1 2 3
  • C1orf145 3 4 5
  • Chromosome 1 Open Reading Frame 145 2 5

External Ids for OBSCN-AS1 Gene

Previous HGNC Symbols for OBSCN-AS1 Gene

  • C1orf145

Summaries for OBSCN-AS1 Gene

GeneCards Summary for OBSCN-AS1 Gene

OBSCN-AS1 (OBSCN Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OBSCN-AS1 Gene

Genomics for OBSCN-AS1 Gene

Regulatory Elements for OBSCN-AS1 Gene

Enhancers for OBSCN-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G228137 1.4 ENCODE dbSUPER 16.6 +71.6 71600 8.8 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF207 OBSCN CICP26 ENSG00000269890 OBSCN-AS1 FAM96AP2 MRPL55 C1orf35 ENSG00000231563 RPL23AP15 HIST3H2BB
GH01G227933 1.4 Ensembl ENCODE dbSUPER 14.1 +278.7 278666 2.6 ATF1 PKNOX1 FOS SP3 TSHZ1 ZNF658 GLIS1 PBX2 NR2C1 HNF4A CICP26 OBSCN OBSCN-AS1 HIST3H3 MIR5008 PRSS38
GH01G228500 1.7 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -287.2 -287237 1.8 PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 ZNF48 ZNF766 ELK1 ZNF143 REST HIST3H3 HIST3H2A HIST3H2BB RPL23AP15 CICP26 OBSCN-AS1 OBSCN C1orf35 RNF187 LOC105373124
GH01G227942 1.4 ENCODE dbSUPER 12.9 +267.9 267948 6.0 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF143 FOS OBSCN-AS1 WNT3A OBSCN IBA57 ENSG00000269934 MRPL55 MIR5008 WNT9A
GH01G228180 1 dbSUPER 18 +32.1 32145 1.6 HDGF CREB3L1 ARNT ARID4B KLF13 REST ZNF592 MEF2D SMARCA4 NBN OBSCN OBSCN-AS1 PIR41583
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OBSCN-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for OBSCN-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000021279 64 1201 ATF1 AGO1 ZNF133 ARID4B SIN3A YBX1 GLI4 ZNF2 ZNF48 ETS1

Genomic Location for OBSCN-AS1 Gene

Chromosome:
1
Start:
228,203,506 bp from pter
End:
228,213,664 bp from pter
Size:
10,159 bases
Orientation:
Minus strand

Genomic View for OBSCN-AS1 Gene

Genes around OBSCN-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OBSCN-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OBSCN-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OBSCN-AS1 Gene

Proteins for OBSCN-AS1 Gene

  • Protein details for OBSCN-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MR7-CA145_HUMAN
    Recommended name:
    Putative uncharacterized protein C1orf145
    Protein Accession:
    Q96MR7
    Secondary Accessions:
    • Q5T438
    • Q8N372

    Protein attributes for OBSCN-AS1 Gene

    Size:
    158 amino acids
    Molecular mass:
    17524 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI15073.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for OBSCN-AS1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OBSCN-AS1 Gene

Post-translational modifications for OBSCN-AS1 Gene

No Post-translational modifications

Other Protein References for OBSCN-AS1 Gene

No data available for DME Specific Peptides for OBSCN-AS1 Gene

Domains & Families for OBSCN-AS1 Gene

Protein Domains for OBSCN-AS1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OBSCN-AS1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OBSCN-AS1 Gene

Function for OBSCN-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OBSCN-AS1 Gene

Localization for OBSCN-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OBSCN-AS1 gene
Compartment Confidence
nucleus 3
mitochondrion 2
extracellular 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for OBSCN-AS1 Gene

Pathways & Interactions for OBSCN-AS1 Gene

SuperPathways for OBSCN-AS1 Gene

No Data Available

Interacting Proteins for OBSCN-AS1 Gene

Gene Ontology (GO) - Biological Process for OBSCN-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OBSCN-AS1 Gene

Drugs & Compounds for OBSCN-AS1 Gene

No Compound Related Data Available

Transcripts for OBSCN-AS1 Gene

mRNA/cDNA for OBSCN-AS1 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OBSCN-AS1 Gene

No ASD Table

Relevant External Links for OBSCN-AS1 Gene

GeneLoc Exon Structure for
OBSCN-AS1
ECgene alternative splicing isoforms for
OBSCN-AS1

Expression for OBSCN-AS1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OBSCN-AS1 Gene:

OBSCN-AS1

Evidence on tissue expression from TISSUES for OBSCN-AS1 Gene

  • Nervous system(2)
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for OBSCN-AS1 Gene

Orthologs for OBSCN-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for OBSCN-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1orf145 35
  • 100 (a)
OneToOne
Species where no ortholog for OBSCN-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OBSCN-AS1 Gene

ENSEMBL:
Gene Tree for OBSCN-AS1 (if available)
TreeFam:
Gene Tree for OBSCN-AS1 (if available)

Paralogs for OBSCN-AS1 Gene

No data available for Paralogs for OBSCN-AS1 Gene

Variants for OBSCN-AS1 Gene

Sequence variations from dbSNP and Humsavar for OBSCN-AS1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs199979779 Uncertain significance 228,212,510(+) GCACC(C/G)GCACG intron-variant, nc-transcript-variant, reference, missense
rs1000274958 -- 228,210,004(+) TTTGA(A/G)TCCTG intron-variant
rs1000307578 -- 228,210,380(+) CCACC(A/T)TGGGG intron-variant
rs1000575751 -- 228,215,630(+) ACTTT(C/G)TCCGT nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1000829971 -- 228,209,291(+) GAGCC(A/C/T)CCCAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OBSCN-AS1 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv1069355 CNV deletion 25765185
nsv1143478 CNV deletion 24896259
nsv1160102 CNV deletion 26073780
nsv474639 CNV novel sequence insertion 20440878
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv827019 CNV loss 20364138
nsv952138 CNV deletion 24416366

Variation tolerance for OBSCN-AS1 Gene

Gene Damage Index Score: 3.74; 57.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OBSCN-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OBSCN-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OBSCN-AS1 Gene

Disorders for OBSCN-AS1 Gene

Relevant External Links for OBSCN-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OBSCN-AS1

No disorders were found for OBSCN-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OBSCN-AS1 Gene

Publications for OBSCN-AS1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  5. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 64

Products for OBSCN-AS1 Gene

Sources for OBSCN-AS1 Gene

Content
Loading form....