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OBFC1 Gene

protein-coding   GIFtS: 52
GCID: GC10M105632

Oligonucleotide/Oligosaccharide-Binding Fold Containing...

  See OBFC1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Oligonucleotide/Oligosaccharide-Binding Fold Containing 11 2     RPA-322
STN12 3 5     Alpha Accessory Factor 442
Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 12 3     bA541N10.22
Suppressor Of Cdc Thirteen Homolog2 3     CST Complex Subunit STN12
AAF442 5     Replication Protein A 32 KDa Subunit2
AAF-442     

External Ids:    HGNC: 262001   Entrez Gene: 799912   Ensembl: ENSG000001079607   OMIM: 6131285   UniProtKB: Q9H6683   

Export aliases for OBFC1 gene to outside databases

Previous GC identifers: GC10M105307 GC10M099268


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OBFC1 Gene:
OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of
DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009
(PubMed 19119139)). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1
(C17ORF106; MIM 613130) (Miyake et al., 2009 (PubMed 19854130)).(supplied by OMIM, Nov 2009)

GeneCards Summary for OBFC1 Gene:
OBFC1 (oligonucleotide/oligosaccharide-binding fold containing 1) is a protein-coding gene. Diseases associated with OBFC1 include idiopathic pulmonary fibrosis. GO annotations related to this gene include single-stranded telomeric DNA binding and single-stranded DNA binding.

UniProtKB/Swiss-Prot: STN1_HUMAN, Q9H668
Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect
telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a
sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to
telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the OBFC1 gene promoter:
         HOXA9B   HOXA9   LHX3b/Lhx3b   Tal-1   Meis-1b   E47   LHX3a/Lhx3a   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOBFC1 promoter sequence
   Search Chromatin IP Primers for OBFC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OBFC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.33   Ensembl cytogenetic band:  10q24.33   HGNC cytogenetic band: 10q25.1

OBFC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OBFC1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M105632:  view genomic region     (about GC identifiers)

Start:
105,637,316 bp from pter      End:
105,678,045 bp from pter
Size:
40,730 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: STN1_HUMAN, Q9H668 (See protein sequence)
Recommended Name: CST complex subunit STN1  
Size: 368 amino acids; 42119 Da
Subunit: Component of the CST complex, composed of TEN1/C17orf106, CTC1/C17orf68 and STN1/OBFC1. Interacts with
TEN1/C17orf106 and CTC1/C17orf68; the interaction is direct. Interacts with ACD/TPP1
2 PDB 3D structures from and Proteopedia for OBFC1:
4JOI (3D)        4JQF (3D)    
Secondary accessions: D3DR99 Q5TCZ0

Explore the universe of human proteins at neXtProt for OBFC1: NX_Q9H668

Explore proteomics data for OBFC1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys55, Lys283
  • Modification sites at PhosphoSitePlus

  • See OBFC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079204.2  
    ENSEMBL proteins: 
     ENSP00000224950   ENSP00000358779  

    OBFC1 Human Recombinant Protein Products:

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    antibodies-online proteins for OBFC1 (14 products) 

     
    antibodies-online peptides for OBFC1

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    antibodies-online antibodies for OBFC1 (31 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR015253 CST_STN1_C
     IPR012340 NA-bd_OB-fold
     IPR004365 NA-bd_OB_tRNA
     IPR014647 CST_STN1

    Graphical View of Domain Structure for InterPro Entry Q9H668

    ProtoNet protein and cluster: Q9H668

    1 Blocks protein domain: IPB004365 OB-fold nucleic acid binding domain

    UniProtKB/Swiss-Prot: STN1_HUMAN, Q9H668
    Similarity: Belongs to the STN1 family
    Similarity: Contains 1 OB DNA-binding domain


    Find genes that share domains with OBFC1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: STN1_HUMAN, Q9H668
    Function: Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect
    telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a
    sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to
    telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003697single-stranded DNA binding ISS--
    GO:0005515protein binding IPI19648609
    GO:0043047single-stranded telomeric DNA binding IDA19648609
         
    Find genes that share ontologies with OBFC1           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for OBFC1:
     Cell division defect  Cells with protrusions  Decreased viability with pacli  Increased S DNA content 
     Increased number of mitotic ce 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for OBFC1

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    Selected qRT-PCR Assays for microRNAs that regulate OBFC1 (see all 38):
    hsa-miR-486-3p hsa-miR-449a hsa-miR-9 hsa-miR-629* hsa-miR-3622b-3p hsa-miR-4330 hsa-miR-3148 hsa-miR-616
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    STN1_HUMAN, Q9H668: Nucleus. Chromosome, telomere
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    extracellular2
    cytosol1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000784nuclear chromosome, telomeric region IDA19648609
    GO:0005634nucleus ISS--
    GO:0005730NOT nucleolus IDA--
    GO:0043231intracellular membrane-bounded organelle IDA--
    GO:0045111intermediate filament cytoskeleton IDA--

    Find genes that share ontologies with OBFC1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including OBFC1: 
              Telomeres & Telomerase in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for OBFC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for OBFC1 (Q9H6681, 2, 3 ENSP000002249504) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TUBGCP4Q9UGJ12, 3, ENSP000002603834MINT-66945 I2D: score=4 STRING: ENSP00000260383
    MED1Q156483, ENSP000003006514I2D: score=1 STRING: ENSP00000300651
    MED14O602443, ENSP000003237204I2D: score=1 STRING: ENSP00000323720
    MED16Q9Y2X03, ENSP000003256124I2D: score=1 STRING: ENSP00000325612
    MED30Q96HR33, ENSP000002973474I2D: score=1 STRING: ENSP00000297347
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000723telomere maintenance IMP19854130
    GO:0010833telomere maintenance via telomere lengthening IMP19648609
    GO:0045740positive regulation of DNA replication ISS--

    Find genes that share ontologies with OBFC1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OBFC1 (STN1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OBFC1 gene: 
    NM_024928.4  

    Unigene Cluster for OBFC1:

    Oligonucleotide/oligosaccharide-binding fold containing 1
    Hs.62314  [show with all ESTs]
    Unigene Representative Sequence: NM_024928
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000224950(uc001kxm.3) ENST00000369764(uc001kxl.3) ENST00000466828
    ENST00000472951
    miRNA
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    hsa-miR-486-3p hsa-miR-449a hsa-miR-9 hsa-miR-629* hsa-miR-3622b-3p hsa-miR-4330 hsa-miR-3148 hsa-miR-616
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      QuantiFast Probe-based Assays in human, mouse, rat OBFC1

    Additional mRNA sequence: 

    AK026212.1 AK057720.1 BC017400.2 

    9 DOTS entries:

    DT.120029  DT.109159  DT.97844036  DT.91761464  DT.100025308  DT.100779229  DT.121283684  DT.95164581 
    DT.95164583 

    Selected AceView cDNA sequences (see all 124):

    AA295283 BF969177 AI078563 W73832 BM454693 CR607240 CA842906 BQ012922 
    AI332546 BM916320 AI371170 BQ001796 CR600104 CR609551 BM968640 BM675406 
    CA311279 AI288528 AA505561 CR617185 BU683198 BI908214 BU597146 BQ017094 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for OBFC1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -                 -                       -                 -                           
    SP2:                                                                          -                           
    SP3:                                                                                                      
    SP4:                                -                                                                     
    SP5:              -                                                                                       


    ECgene alternative splicing isoforms for OBFC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OBFC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTCTGCTG
    OBFC1 Expression
    About this image

    OBFC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OBFC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.62314
        Pathway & Disease-focused RT2 Profiler PCR Array including OBFC1: 
              Telomeres & Telomerase in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OBFC1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Obfc11 , 5 oligonucleotide/oligosaccharide-binding fold containing more1, 5 77.72(n)1
    70.92(a)1
      19 (39.64 cM)5
    1086891  NM_175360.21  NP_780569.11 
     475010335 
    chicken
    (Gallus gallus)
    Aves OBFC11 oligonucleotide/oligosaccharide-binding fold containing more 62.44(n)
    58.4(a)
      423877  XM_421742.4  XP_421742.3 
    lizard
    (Anolis carolinensis)
    Reptilia OBFC16
    oligonucleotide/oligosaccharide-binding fold conta...
    49(a)
    1 ↔ 1
    3(41310977-41338668)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480200632   -- 68.78(n)    48020063 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc641742 hypothetical protein MGC64174 76.59(n)   393360  BC053298.1 


    ENSEMBL Gene Tree for OBFC1 (if available)
    TreeFam Gene Tree for OBFC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OBFC1 gene

    Find genes that share paralogs with OBFC1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for OBFC1
    PGOHUM00000238836 PGOHUM00000235818


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OBFC1 (see all 938)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1404552261,2
    --105636857(+) GAACAG/TTTGCT 1 -- ds50010--------
    rs1908298311,2
    --105636900(+) TCTTGC/TGTTGA 1 -- ds50010--------
    rs29026381,2
    C,F,O,H--105636989(+) TCTTAT/CTAAAG 1 -- ds500123Minor allele frequency- C:0.16NS EA NA CSA WA 2488
    rs345470361,2
    C,F--105637026(+) TCCTTC/TGTGGT 1 -- ds50017Minor allele frequency- T:0.11NA WA 428
    rs171160911,2
    C,F--105637027(+) CCTTCG/ATGGTA 1 -- ds50013Minor allele frequency- A:0.01NA 140
    rs1443261371,2
    --105637183(+) CAGGGC/TTATGC 1 -- ds50010--------
    rs1853461721,2
    --105637362(+) AATACA/GGTAGA 1 -- ut310--------
    rs1477880461,2
    C--105637387(+) AGTGCA/GAGTTC 1 -- ut310--------
    rs10485851,2
    F--105637589(-) GGCTCA/G/TCCAGA 2 -- ut313MN NA 188
    rs1406655671,2
    C--105637641(+) TGTAG-/TTAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for OBFC1 (105637316 - 105678045 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for OBFC1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1740571CNV Insertion17803354
    nsv895982CNV Loss21882294
    nsv7531CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613128    OMIM disorders: --

    1 disease for OBFC1:    
    About MalaCards
    idiopathic pulmonary fibrosis


    Find genes that share disorders with OBFC1           About GenesLikeMe

    Genetic Association Database (GAD): OBFC1
    Human Genome Epidemiology (HuGE) Navigator: OBFC1 (3 documents)

    Export disorders for OBFC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OBFC1 gene, integrated from 10 sources (see all 28):
    (articles sorted by number of sources associating them with OBFC1)
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    1. OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. (PubMed id 19648609)1, 2, 9 Wan M.... Liu D. (J. Biol. Chem. 2009)
    2. A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids. (PubMed id 21460842)1, 4 Cha P.C....Nakamura Y. (Nat. Genet. 2011)
    3. Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. (PubMed id 20421499)1, 4 Levy D....Aviv A. (Proc. Natl. Acad. Sci. U.S.A. 2010)
    4. RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. (PubMed id 19854130)1, 2 Miyake Y.... Ishikawa F. (Mol. Cell 2009)
    5. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)1, 4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)
    6. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79991 HGNC: 26200 AceView: OBFC1 Ensembl:ENSG00000107960 euGenes: HUgn79991
    ECgene: OBFC1 H-InvDB: OBFC1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OBFC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OBFC1 gene:
    Search GeneIP for patents involving OBFC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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