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Aliases & Descriptions for OBFC1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| AAF-44 2 | | FLJ22559 1, 2 | | OTTHUMP00000020417 2 | | OTTHUMP00000020418 2 | | RP11-541N10.2 2 | | RPA-32 2 | | bA541N10.2 1, 2 |
| | | Descriptions |
|---|
| alpha accessory factor 44 2 | | oligonucleotide/oligosaccharide-binding fold containing 1 2 | | replication protein A 32 kDa subunit 2 |
|
| | Search outside databases for aliases for OBFC1 genePrevious GC identifer: GC10M105307 |
Summaries for OBFC1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: OBFC1_HUMAN, Q9H668Function: May bind nucleic acids or oligosaccharides |
Genomic Location for OBFC1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the OBFC1 gene 
Entrez Gene cytogenetic band: 10q24.33 Ensembl cytogenetic band: 10q24.33 HGNC cytogenetic band: 10q25.1OBFC1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M105632:
(about GC identifiers)
Start:
|
105,632,290 bp from pter |
End:
|
105,667,956 bp from pter |
Size:
|
35,667 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000010.9 NT_030059.12
| Proteins for OBFC1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: OBFC1_HUMAN, Q9H668 (See
protein sequence)Recommended Name: Oligonucleotide/oligosaccharide-binding fold-containing protein 1 Size: 368 amino acids; 42119 Da
Secondary accessions: Q5TCZ0REFSEQ proteins: NP_079204.2
ENSEMBL proteins: ENSP00000224950 ENSP00000358779
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: OBFC1 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- | About this table
Antibodies for OBFC1: Assays for OBFC1: | Protein
Domains/ Families for OBFC1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9H668
ProtoNet protein and cluster: Q9H668 1 Blocks protein family: IPB004365 OB-fold nucleic acid binding domain
| Gene Function for OBFC1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_024928
Applied Biosystems Silencer® siRNAs for OBFC1
Sigma-Aldrich siRNA for OBFC1  Sigma-Aldrich shRNA for OBFC1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_024928                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_024928                                  untagged cDNA clone in CMV expression vector: NM_024928 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: BC017400
UniProtKB/Swiss-Prot: OBFC1_HUMAN, Q9H668Function: May bind nucleic acids or oligosaccharides2 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0003676 | nucleic acid binding |
IEA | -- | About this table | Pathways & Interactions for OBFC1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
3 Interacting proteins for OBFC1 (ENSP000002249503 Q9H6682) via UniProtKB, MINT, and/or STRINGAbout this table
1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | About this table
|
Drugs & Compounds for OBFC1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for OBFC1
|
Transcripts for OBFC1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|                OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_024928
Sigma-Aldrich siRNA for OBFC1  Sigma-Aldrich shRNA for OBFC1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_024928 REFSEQ mRNAs for OBFC1 gene: NM_024928.4
Applied Biosystems TaqMan ® Gene Expression Assays: NM_024928               OriGene GFP tagged cDNA clone in CMV expression vector: NM_024928                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_024928                                  untagged cDNA clone in CMV expression vector: NM_024928  Additional cDNA sequence: AK026212.1 AK057720.1 BC017400.2 CR600104.1 CR607240.1 CR609551.1 CR613200.1 CR617185.1 9 DOTS entries: DT.120029 DT.109159 DT.97844036 DT.91761464 DT.100025308 DT.100779229 DT.121283684 DT.95164581 DT.95164583 24/124 AceView cDNA sequences (see all 124
):CA311279 AA295283 AI288528 CR609551 BF969177 CA842906 BQ001796 AI332546 CR617185 BQ012922 BM968640 BM675406 BM454693 CR600104 AI371170 W73832 AI078563 CR607240 BM916320 AA505561 CA425283 BX952699 BM850716 AA143157
highest scoring ESTs for OBFC1:AA142978 AW964268 BC017400 BE019787 BF184393 BF797125 BG330913 BG765570 BI819194 BI908214 Unigene Cluster for OBFC1: Oligonucleotide/oligosaccharide-binding fold containing 1 Hs.62314 [show with all ESTs]Unigene Representative Sequence: NM_024928
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for OBFC1
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | |
| SP1: | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for OBFC1
2 Ensembl transcripts including schematic representations: ENST00000224950
ENST00000369764
|
Expression for OBFC1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| OBFC1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for OBFC1
1 / 2 / 3 9 probe-sets matching OBFC1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: ATTTCTGCTG
SOURCE GeneReport for Unigene cluster: Hs.62314
|
Orthologs for OBFC1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for OBFC1 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for OBFC1
ENSEMBL Gene Tree for OBFC1 | Paralogs for OBFC1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for OBFC1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for OBFC1 (up to first 250kb)
|
Disorders & Mutations for OBFC1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| Human Genome Epidemiology Navigator: OBFC1 (1 document)
|
Medical News for OBFC1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for OBFC1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 7 PubMed articles for OBFC1 gene: |
Search for OBFC1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing OBFC1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing OBFC1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OBFC1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for OBFC1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for OBFC1:

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| | | | Search Tocris compounds for OBFC1 |
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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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