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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OAZ2 Gene

protein-coding   GIFtS: 54
GCID: GC15M064979

Ornithine Decarboxylase Antizyme 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ornithine Decarboxylase Antizyme 21 2
AZ22 3
ODC-Az 22 3

External Ids:    HGNC: 80961   Entrez Gene: 49472   Ensembl: ENSG000001803047   OMIM: 6041525   UniProtKB: O951903   

Export aliases for OAZ2 gene to outside databases

Previous GC identifers: GC15P060699 GC15M9D0083 GC15M062558 GC15M062766 GC15M041805


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OAZ2 Gene:
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently
rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation
of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is
auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits
ornithine decarboxylase but does not accelerate its degradation. (provided by RefSeq, Jul 2008)

GeneCards Summary for OAZ2 Gene: 
OAZ2 (ornithine decarboxylase antizyme 2) is a protein-coding gene. Diseases associated with OAZ2 include cleidocranial dysplasia, and neuroblastoma, and among its related super-pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Metabolic pathways. GO annotations related to this gene include ornithine decarboxylase inhibitor activity. An important paralog of this gene is OAZ3.

UniProtKB/Swiss-Prot: OAZ2_HUMAN, O95190
Function: Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase
degeneration (By similarity)

Gene Wiki entry for OAZ2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OAZ2 gene promoter:
         STAT1   STAT4   SREBP-1c   STAT1beta   STAT1alpha   SREBP-1b   SREBP-1a   STAT2   STAT3   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOAZ2 promoter sequence
   Search SABiosciences Chromatin IP Primers for OAZ2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OAZ2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.31   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22.31

OAZ2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OAZ2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M064979:  view genomic region     (about GC identifiers)

Start:
64,979,772 bp from pter      End:
64,995,480 bp from pter
Size:
15,709 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OAZ2_HUMAN, O95190 (See protein sequence)
Recommended Name: Ornithine decarboxylase antizyme 2  
Size: 189 amino acids; 21011 Da
Subcellular location: Nucleus (By similarity)
Ribosomal frameshifting: 1 isoform:  O95190-1   

Explore the universe of human proteins at neXtProt for OAZ2: NX_O95190

Explore proteomics data for OAZ2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95190

  • OAZ2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OAZ2 Protein Expression
    REFSEQ proteins: NP_002528.1  
    ENSEMBL proteins: 
     ENSP00000463013   ENSP00000462354   ENSP00000463729   ENSP00000462192  
    Reactome Protein details: O95190
    Human Recombinant Protein Products for OAZ2: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OAZ2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--

    OAZ2 for ontologies           About GeneDecksing



    OAZ2 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for OAZ2 

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    Cloud-Clone Corp. ELISAs for OAZ2 
    Cloud-Clone Corp. CLIAs for OAZ2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR002993 ODC_AZ
     IPR016181 Acyl_CoA_acyltransferase

    Graphical View of Domain Structure for InterPro Entry O95190

    ProtoNet protein and cluster: O95190

    1 Blocks protein domain: IPB002993 Ornithine decarboxylase antizyme

    UniProtKB/Swiss-Prot: OAZ2_HUMAN, O95190
    Similarity: Belongs to the ODC antizyme family


    OAZ2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OAZ2_HUMAN, O95190
    Function: Binds to, and destabilizes, ornithine decarboxylase. Does not accelerate ornithine decarboxylase
    degeneration (By similarity)

         Genatlas biochemistry entry for OAZ2:
    ornithine decarboxylase antizyme 2,negative regulator of polyamine level

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004857enzyme inhibitor activity ----
    GO:0005515protein binding ----
    GO:0008073ornithine decarboxylase inhibitor activity IEA--
         
    OAZ2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OAZ2:
     Decreased viability 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OAZ2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OAZ2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OAZ2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OAZ2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OAZ2
    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate OAZ2 (see all 23):
    hsa-miR-579 hsa-miR-3607-3p hsa-miR-3607-5p hsa-miR-4307 hsa-miR-1257 hsa-miR-570 hsa-miR-3143 hsa-miR-2116
    SwitchGear 3'UTR luciferase reporter plasmidOAZ2 3' UTR sequence
    Inhib. RNA
    Products:
        
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OAZ2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for OAZ2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1CDK-mediated phosphorylation and removal of Cdc6
    Regulation of ornithine decarboxylase (ODC)0.80
    2Metabolism
    Metabolism0.40
    3Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for OAZ2
        Regulation of ornithine decarboxylase (ODC)
    Metabolism
    Metabolism of amino acids and derivatives



    OAZ2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for OAZ2

    3 Interacting proteins for OAZ2 (O951903) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AZIN1O149773I2D: score=2 
    ODC1P119263I2D: score=2 
    OAZ1P543683I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006521regulation of cellular amino acid metabolic process TAS--
    GO:0006595polyamine metabolic process TAS9428668
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    OAZ2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    OAZ2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OAZ2

    1 HMDB Compound for OAZ2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Ornithine(+)-S-Ornithine (see all 9)70-26-8--

    1 DrugBank Compound for OAZ2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Ornithine(S)-2,5-Diaminopentanoate (see all 4)70-26-8target--17139284 17016423

    1 Novoseek inferred chemical compound relationship for OAZ2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ornithine 56.2 1 19960435 (1), 10352227 (1)

    Search CenterWatch for drugs/clinical trials and news about OAZ2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OAZ2 gene: 
    NM_002537.2  

    Unigene Cluster for OAZ2:

    Ornithine decarboxylase antizyme 2
    Hs.744924  [show with all ESTs]
    Unigene Representative Sequence: NM_002537
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326005(uc002ano.2) ENST00000558194 ENST00000560258 ENST00000559753
    ENST00000560837 ENST00000559912 ENST00000560781 ENST00000559665 ENST00000559555

    miRNA
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    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate OAZ2 (see all 23):
    hsa-miR-579 hsa-miR-3607-3p hsa-miR-3607-5p hsa-miR-4307 hsa-miR-1257 hsa-miR-570 hsa-miR-3143 hsa-miR-2116
    SwitchGear 3'UTR luciferase reporter plasmidOAZ2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OAZ2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OAZ2
    Clone
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    GenScript: all cDNA clones in your preferred vector: OAZ2 (NM_002537)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OAZ2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat OAZ2
    Sirion Biotech Customized lentivirus for stable overexpression of OAZ2 
                         Customized lentivirus expression plasmids for stable overexpression of OAZ2 
    Primer
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    OriGene qPCR primer pairs and template standards for OAZ2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OAZ2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OAZ2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OAZ2

    Additional mRNA sequence: 

    AF057297.1 AF242521.1 BC035493.2 BC047755.1 BC063577.1 BC073877.1 BC092483.1 BC119629.1 
    BC119630.1 BC127630.1 BC127631.1 BC148316.2 

    22 DOTS entries:

    DT.100835110  DT.448384  DT.95172493  DT.100835867  DT.100835863  DT.97762211  DT.99980709  DT.121043899 
    DT.100835859  DT.92447935  DT.121043905  DT.92447930  DT.121043901  DT.95172487  DT.100038038  DT.100695819 
    DT.100801156  DT.100835870  DT.121043848  DT.121043900  DT.95206472  DT.308927 

    24/633 AceView cDNA sequences (see all 633):

    CR626244 BU506882 BM127443 AI698638 AI889062 BU733397 BU166810 CD370633 
    BM811047 AA452880 BP356562 BQ891939 BM839424 BX423502 BU950595 BF941716 
    BQ286375 CR624771 CR611250 BE206997 AI352705 CR590996 AI337193 BQ186450 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for OAZ2 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9 ^ 10a · 10b · 10c · 10d · 10e ^ 11
    SP1:                    -     -     -     -                 -                             -                                             
    SP2:                    -     -     -     -                 -           -     -     -     -                                             
    SP3:                    -     -     -     -                 -                             -                                             
    SP4:                          -     -     -                 -                             -                                             
    SP5:                                                        -                             -                                             


    ECgene alternative splicing isoforms for OAZ2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OAZ2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTGGAGGG
    OAZ2 Expression
    About this image


    See OAZ2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OAZ2

    SOURCE GeneReport for Unigene cluster: Hs.744924
        SABiosciences Custom PCR Arrays for OAZ2
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OAZ2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OAZ2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for OAZ2 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Oaz21 , 5 ornithine decarboxylase antizyme 21, 5 97.35(n)1
    99.47(a)1
      9 (35.45 cM)5
    182471  NM_010952.31  NP_035082.11 
     656680015 
    chicken
    (Gallus gallus)
    Aves OAZ21 ornithine decarboxylase antizyme 2 86.24(n)
    91.01(a)
      427481  NM_001142862.1  NP_001136334.1 
    lizard
    (Anolis carolinensis)
    Reptilia OAZ26
    Uncharacterized protein
    91(a)
    1 ↔ 1
    GL343490.1(570376-581678)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC686102 hypothetical protein MGC68610 80.19(n)    BC059788.1 
    zebrafish
    (Danio rerio)
    Actinopterygii oaz12 ornithine decarboxylase antizyme 1 78.16(n)   259192  AB017117.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Oda6
    Ornithine decarboxylase antizyme
    15(a)
    1 → many
    2R(8054077-8061767)


    ENSEMBL Gene Tree for OAZ2 (if available)
    TreeFam Gene Tree for OAZ2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OAZ2 gene
    OAZ32  OAZ12  
    2 SIMAP similar genes for OAZ2 using alignment to 4 protein entries:     OAZ2_HUMAN (see all proteins):
    OAZ1    OAZ3

    OAZ2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/329 SNPs in OAZ2 are shown (see all 329)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs74037511,2
    C,F,A,H--64979291(+) ACTGAC/GAGCTT 1 -- ds500117Minor allele frequency- G:0.29NS EA NA WA CSA 795
    rs1906958711,2
    --64979300(+) TTATTC/TATCAG 1 -- ds50010--------
    rs1408245381,2
    --64979340(+) CTTAGA/GACACT 1 -- ds50010--------
    rs169481821,2
    C,F,H--64979382(+) AGGTGT/GGTGCT 1 -- ds500119Minor allele frequency- G:0.12NA NS WA CSA 1858
    rs1815650351,2
    --64979462(+) ACCCAA/GCCTCC 1 -- ds50010--------
    rs1446204931,2
    --64979518(+) GGGTAC/TAGCCT 1 -- ds50010--------
    rs1125507211,2
    C--64979537(+) GAAGCTGAT/-  
            
    TGATA
    1 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs569954571,2
    C--64979549(+) CACAT-/ATCTCTC 1 -- ds50010--------
    rs719317421,2
    C--64979550(+) ACACA-/ATTCTCT 1 -- ds50010--------
    rs1385786611,2
    --64979634(+) AGAGAA/CCTCAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for OAZ2 (64979772 - 64995480 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for OAZ2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv833038CNV Loss17160897
    esv22620CNV Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604152    OMIM disorders: --

    2 diseases for OAZ2:    About MalaCards
    cleidocranial dysplasia    neuroblastoma


    OAZ2 for disorders           About GeneDecksing


    Export disorders for OAZ2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OAZ2 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with OAZ2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure of human ornithine decarboxylase antizyme 2 gene. (PubMed id 10352227)1, 2, 3, 9 Zhou J.... Gesteland R.F. (1999)
    2. A second mammalian antizyme: conservation of programmed ribosomal frameshifting. (PubMed id 9782076)1, 2, 3 Ivanov I.P.... Atkins J.F. (1998)
    3. The polyamine metabolism genes ornithine decarboxylas e and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification. (PubMed id 19960435)1, 9 Geerts D....Bachmann A.S. (2010)
    4. Effects of promoter methylation on increased expressio n of polyamine biosynthetic genes in suicide. (PubMed id 23260169)1 Gross J.A....Turecki G. (2013)
    5. Effects of histone modifications on increased expressi on of polyamine biosynthetic genes in suicide. (PubMed id 22008221)1 Fiori L.M....Turecki G. (2012)
    6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    7. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    8. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
    9. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
    10. Regulation of all members of the antizyme family by antizyme inhibitor. (PubMed id 15355308)1 Mangold U. and Leberer E. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4947 HGNC: 8096 AceView: OAZ2 Ensembl:ENSG00000180304 euGenes: HUgn4947
    ECgene: OAZ2 H-InvDB: OAZ2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OAZ2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OAZ2 gene:
    Search GeneIP for patents involving OAZ2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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