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Aliases for OAT Gene

Aliases for OAT Gene

  • Ornithine Aminotransferase 2 2 3 5
  • Ornithine Delta-Aminotransferase 3 4
  • Gyrate Atrophy 2 3
  • EC 2.6.1.13 4 58
  • Ornithine Aminotransferase, Mitochondrial 3
  • Ornithine Aminotransferase Precursor 2
  • Ornithine--Oxo-Acid Aminotransferase 4
  • Ornithine-Oxo-Acid Aminotransferase 3
  • Testicular Tissue Protein Li 130 3
  • EC 2.6.1 58
  • OATASE 3
  • GACR 3
  • HOGA 3
  • OKT 3

External Ids for OAT Gene

Previous GeneCards Identifiers for OAT Gene

  • GC10M125055
  • GC10M125289
  • GC10M126126
  • GC10M125660
  • GC10M126075
  • GC10M119770

Summaries for OAT Gene

Entrez Gene Summary for OAT Gene

  • This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010]

GeneCards Summary for OAT Gene

OAT (Ornithine Aminotransferase) is a Protein Coding gene. Diseases associated with OAT include Gyrate Atrophy Of Choroid And Retina With Or Without Ornithinemia and Choroid Disease. Among its related pathways are Metabolism and Urea cycle and metabolism of amino groups. GO annotations related to this gene include pyridoxal phosphate binding and ornithine-oxo-acid transaminase activity.

Additional gene information for OAT Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OAT Gene

Genomics for OAT Gene

Regulatory Elements for OAT Gene

Enhancers for OAT Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H124412 1.4 ENCODE dbSUPER 16.7 +1.3 1286 10 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 OAT NKX1-2 EEF1AKMT2 LOC105378536
GH10H124388 1.1 Ensembl ENCODE 18 +29.8 29814 1 ELF3 RB1 BRCA1 RAD21 EGR1 ZNF143 RCOR1 CREM SMARCA5 ZNF654 OAT CHST15 LOC105378536
GH10H124354 1.2 Ensembl ENCODE 5.8 +64.0 63962 1 ARID4B FEZF1 ZNF2 YY1 TCF12 GLIS2 ELK1 ZNF143 ATF7 SP3 EEF1AKMT2 CHST15 OAT LOC105378536
GH10H124434 1 ENCODE dbSUPER 6 -16.5 -16532 2 PKNOX1 TFAP4 SAP130 CEBPG FEZF1 ZNF384 ZNF121 ETV6 ATF7 RUNX3 OAT ZRANB1 OATP1
GH10H124406 0.4 dbSUPER 7.6 +11.4 11365 1 HNF4A NKX1-2 CHST15 FAM53B OAT LOC105378536
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OAT on UCSC Golden Path with GeneCards custom track

Promoters for OAT Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000034785 576 2001 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 FOS SP3 SP5

Genomic Location for OAT Gene

Chromosome:
10
Start:
124,397,303 bp from pter
End:
124,418,976 bp from pter
Size:
21,674 bases
Orientation:
Minus strand

Genomic View for OAT Gene

Genes around OAT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OAT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OAT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OAT Gene

Proteins for OAT Gene

  • Protein details for OAT Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P04181-OAT_HUMAN
    Recommended name:
    Ornithine aminotransferase, mitochondrial
    Protein Accession:
    P04181
    Secondary Accessions:
    • D3DRF0
    • Q16068
    • Q16069
    • Q68CS0
    • Q6IAV9
    • Q9UD03

    Protein attributes for OAT Gene

    Size:
    439 amino acids
    Molecular mass:
    48535 Da
    Cofactor:
    Name=pyridoxal 5-phosphate; Xref=ChEBI:CHEBI:597326;
    Quaternary structure:
    • Homohexamer.

    Three dimensional structures from OCA and Proteopedia for OAT Gene

    Alternative splice isoforms for OAT Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OAT Gene

Selected DME Specific Peptides for OAT Gene

P04181:
  • VEPIQGE
  • VLGEYEE
  • IRFAPPL
  • VRGKGLLNAIVI
  • TLTSRAF
  • HGSTYGGNPL
  • KYGAHNYHPLPVAL
  • KVLPMNTGVE
  • EPIQGEAG
  • DEIQTGL
  • LGKALSGG
  • DAWKVCL
  • YPVSAVL
  • QTGLARTG
  • PGEHGST
  • LFIADEIQ
  • YSAVNQGH

Post-translational modifications for OAT Gene

  • Ubiquitination at posLast=4949, Lys66, Lys374, and posLast=392392
  • Modification sites at PhosphoSitePlus

Domains & Families for OAT Gene

Gene Families for OAT Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for OAT Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P04181

UniProtKB/Swiss-Prot:

OAT_HUMAN :
  • Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Family:
  • Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
genes like me logo Genes that share domains with OAT: view

Function for OAT Gene

Molecular function for OAT Gene

GENATLAS Biochemistry:
ornithine aminotransferase,proline and ornithine metabolic pathway,mitochondrial matrix
UniProtKB/Swiss-Prot CatalyticActivity:
L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

Enzyme Numbers (IUBMB) for OAT Gene

Phenotypes From GWAS Catalog for OAT Gene

Gene Ontology (GO) - Molecular Function for OAT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004587 ornithine-oxo-acid transaminase activity EXP 6819292
GO:0008483 transaminase activity IEA --
GO:0016740 transferase activity IEA --
GO:0030170 pyridoxal phosphate binding IBA --
GO:0042802 identical protein binding IBA --
genes like me logo Genes that share ontologies with OAT: view
genes like me logo Genes that share phenotypes with OAT: view

Human Phenotype Ontology for OAT Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for OAT Gene

MGI Knock Outs for OAT:

Animal Model Products

CRISPR Products

miRNA for OAT Gene

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OAT
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Transcription Factor Targets and HOMER Transcription for OAT Gene

Localization for OAT Gene

Subcellular locations from UniProtKB/Swiss-Prot for OAT Gene

Mitochondrion matrix.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OAT gene
Compartment Confidence
mitochondrion 5
nucleus 5
plasma membrane 1
extracellular 1
cytoskeleton 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (3)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for OAT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion TAS,IDA --
GO:0005759 mitochondrial matrix NAS,TAS --
genes like me logo Genes that share ontologies with OAT: view

Pathways & Interactions for OAT Gene

genes like me logo Genes that share pathways with OAT: view

UniProtKB/Swiss-Prot P04181-OAT_HUMAN

  • Pathway: Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.

Gene Ontology (GO) - Biological Process for OAT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007601 visual perception TAS 2793865
GO:0008652 cellular amino acid biosynthetic process TAS --
GO:0034214 protein hexamerization IDA 9514741
GO:0055129 L-proline biosynthetic process IEA --
genes like me logo Genes that share ontologies with OAT: view

No data available for SIGNOR curated interactions for OAT Gene

Drugs & Compounds for OAT Gene

(17) Drugs for OAT Gene - From: DrugBank, ClinicalTrials, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ornithine Approved Nutra Target 70
Probenecid Approved Pharma Inhibition, Inhibitor 30
Famotidine Approved Pharma Histamine H2-receptor antagonist 62
Glutamic Acid Approved Nutra Full agonist, Agonist 236
Canaline Experimental Pharma Target, inhibitor 0

(13) Additional Compounds for OAT Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
L-Canaline
  • L-2-Amino-4-(aminooxy)butyrate
  • L-2-Amino-4-(aminooxy)butyric acid
  • L-a-Amino-g-(aminooxy)-N-butyric acid
  • L-alpha-Amino-gamma-(aminooxy)-N-butyric acid
496-93-5
L-Glutamic gamma-semialdehyde
  • Glutamate-semialdehyde
  • Glutamic gamma-semialdehyde
  • L-Glutamate 5-semialdehyde
  • L-Glutamate-5-semialdehyde
  • L-Glutamate-gamma-semialdehyde
496-92-4
Oxoglutaric acid
  • 2-Ketoglutarate
  • 2-Ketoglutaric acid
  • 2-Oxo-1,5-pentanedioate
  • 2-Oxo-1,5-pentanedioic acid
  • 2-Oxoglutarate
328-50-7
genes like me logo Genes that share compounds with OAT: view

Transcripts for OAT Gene

Unigene Clusters for OAT Gene

Ornithine aminotransferase:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OAT
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OAT Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ·
SP1: - - - - - - - - - - -
SP2: - - - -
SP3: - -
SP4: - - - -
SP5:
SP6: -
SP7: -
SP8: - - - - - - - -
SP9: - - - -
SP10: - - - -
SP11: - - -
SP12: - - -
SP13: -

ExUns: 13c
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for OAT Gene

GeneLoc Exon Structure for
OAT
ECgene alternative splicing isoforms for
OAT

Expression for OAT Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OAT Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for OAT Gene

This gene is overexpressed in Fetal gut (10.1), Salivary gland (9.9), Fetal testis (6.2), and Pancreatic juice (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for OAT Gene



Protein tissue co-expression partners for OAT Gene

NURSA nuclear receptor signaling pathways regulating expression of OAT Gene:

OAT

SOURCE GeneReport for Unigene cluster for OAT Gene:

Hs.523332

Evidence on tissue expression from TISSUES for OAT Gene

  • Nervous system(5)
  • Kidney(4.7)
  • Liver(4.6)
  • Skin(3.8)
  • Blood(3.4)
  • Eye(2.9)
  • Intestine(2.7)
  • Bone marrow(2.6)
  • Lymph node(2.5)
  • Lung(2.4)
  • Spleen(2.2)
  • Stomach(2.1)
  • Thyroid gland(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for OAT Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • nervous
  • skeletal muscle
Organs:
Head and neck:
  • brain
  • cranial nerve
  • eye
  • head
Limb:
  • lower limb
  • upper limb
General:
  • peripheral nervous system
genes like me logo Genes that share expression patterns with OAT: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OAT Gene

Orthologs for OAT Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for OAT Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OAT 33 34
  • 99.85 (n)
cow
(Bos Taurus)
Mammalia OAT 33 34
  • 89.6 (n)
dog
(Canis familiaris)
Mammalia OAT 33 34
  • 88 (n)
oppossum
(Monodelphis domestica)
Mammalia OAT 34
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 87 (a)
OneToMany
-- 34
  • 80 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Oat 33 16 34
  • 84.51 (n)
rat
(Rattus norvegicus)
Mammalia Oat 33
  • 83.9 (n)
chicken
(Gallus gallus)
Aves OAT 33 34
  • 78.44 (n)
lizard
(Anolis carolinensis)
Reptilia OAT 34
  • 84 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia oat.1 33
  • 72.06 (n)
Str.6824 33
African clawed frog
(Xenopus laevis)
Amphibia oat-prov 33
zebrafish
(Danio rerio)
Actinopterygii oat 33 34
  • 70.03 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.242 33
fruit fly
(Drosophila melanogaster)
Insecta CG8782 35
  • 70 (a)
Oat 33 34
  • 64.49 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004793 33
  • 65.68 (n)
worm
(Caenorhabditis elegans)
Secernentea C16A3.10a 35
  • 66 (a)
C16A3.10 33 34
  • 64.91 (n)
C16A3.10b 35
  • 63 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B05247g 33
  • 57.96 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CAR2 33 34 36
  • 56.28 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AER123W 33
  • 54.36 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons DELTA-OAT 33
  • 55.83 (n)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.21 33
rice
(Oryza sativa)
Liliopsida Os03g0643300 33
  • 53.9 (n)
Os.18830 33
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 68 (a)
OneToOne
bread mold
(Neurospora crassa)
Ascomycetes NCU00194 33
  • 57.78 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes car2 33
  • 57.54 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.12481 33
Species where no ortholog for OAT was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OAT Gene

ENSEMBL:
Gene Tree for OAT (if available)
TreeFam:
Gene Tree for OAT (if available)

Paralogs for OAT Gene

No data available for Paralogs for OAT Gene

Variants for OAT Gene

Sequence variations from dbSNP and Humsavar for OAT Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11553554 Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870] 124,412,020(-) GTATG(A/G)TGCAC intron-variant, reference, missense, utr-variant-5-prime
rs121965037 Pathogenic, Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870] 124,412,009(-) ACAAC(C/T)ACCAT intron-variant, reference, missense, utr-variant-5-prime
rs121965038 Pathogenic, Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870] 124,408,887(-) GCATT(G/T)TCACC intron-variant, reference, missense, utr-variant-5-prime
rs121965039 Pathogenic, Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870] 124,408,601(-) AGCTC(A/G/T)TAAGT intron-variant, reference, missense, utr-variant-5-prime
rs121965040 Pathogenic, Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870] 124,405,545(-) GGGTA(C/G)GACGT reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for OAT Gene

Variant ID Type Subtype PubMed ID
dgv530n106 CNV deletion 24896259
nsv1069086 CNV deletion 25765185
nsv825602 CNV gain 20364138
nsv825603 CNV gain 20364138
nsv832012 CNV gain+loss 17160897
nsv948214 CNV duplication 23825009
nsv975068 CNV duplication 23825009

Variation tolerance for OAT Gene

Residual Variation Intolerance Score: 39.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.07; 21.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OAT Gene

Human Gene Mutation Database (HGMD)
OAT
SNPedia medical, phenotypic, and genealogical associations of SNPs for
OAT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OAT Gene

Disorders for OAT Gene

MalaCards: The human disease database

(14) MalaCards diseases for OAT Gene - From: HGMD, OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
gyrate atrophy of choroid and retina with or without ornithinemia
  • gyrate atrophy
choroid disease
  • abnormality of the choroid
parapsoriasis
  • digitate dermatosis
norrie disease
  • atrophia bulborum hereditaria
cerebral creatine deficiency syndrome 3
  • agat deficiency
- elite association - COSMIC cancer census association via MalaCards
Search OAT in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

OAT_HUMAN
  • Hyperornithinemia with gyrate atrophy of choroid and retina (HOGA) [MIM:258870]: A disorder clinically characterized by a triad of progressive chorioretinal degeneration, early cataract formation, and type II muscle fiber atrophy. Characteristic chorioretinal atrophy with progressive constriction of the visual fields leads to blindness at the latest during the sixth decade of life. Patients generally have normal intelligence. {ECO:0000269 PubMed:1612597, ECO:0000269 PubMed:1737786, ECO:0000269 PubMed:23076989, ECO:0000269 PubMed:2793865, ECO:0000269 PubMed:3375240, ECO:0000269 PubMed:7668253, ECO:0000269 PubMed:7887415}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for OAT Gene

hyperornithinemia,with gyrate atrophy of choroid and retina

Relevant External Links for OAT

Genetic Association Database (GAD)
OAT
Human Genome Epidemiology (HuGE) Navigator
OAT
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OAT
genes like me logo Genes that share disorders with OAT: view

Publications for OAT Gene

  1. Molecular pathology of gyrate atrophy of the choroid and retina due to ornithine aminotransferase deficiency. (PMID: 1682785) Ramesh V … Shih VE (Molecular biology & medicine 1991) 2 3 4 22 60
  2. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. (PMID: 9878407) Storici P … Jansonius JN (Journal of molecular biology 1999) 3 4 22 60
  3. Crystal structure of human recombinant ornithine aminotransferase. (PMID: 9514741) Shen BW … Schirmer T (Journal of molecular biology 1998) 3 4 22 60
  4. Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition. (PMID: 9309222) Shah SA … Brünger AT (Structure (London, England : 1993) 1997) 3 4 22 60
  5. Pyridoxine-responsive gyrate atrophy of the choroid and retina: clinical and biochemical correlates of the mutation A226V. (PMID: 7887415) Michaud J … Mitchell GA (American journal of human genetics 1995) 3 4 22 60

Products for OAT Gene

Sources for OAT Gene

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