Aliases for OASL Gene
External Ids for OASL Gene
Previous GeneCards Identifiers for OASL Gene
GeneCards Summary for OASL Gene
OASL (2'-5'-Oligoadenylate Synthetase Like) is a Protein Coding gene. Diseases associated with OASL include Microphthalmia With Limb Anomalies. Among its related pathways are PI3K-Akt signaling pathway and Interferon gamma signaling. GO annotations related to this gene include poly(A) RNA binding and double-stranded RNA binding. An important paralog of this gene is OAS1.
UniProtKB/Swiss-Prot for OASL Gene
Does not have 2-5-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.