OAS3 Gene
protein-coding GIFtS: 60
GCID: GC12P113376
|
|
2'-5'-oligoadenylate synthetase 3, 100kDa(Previous name: 2'-5'-oligoadenylate synthetase 3 (100 kD) )
| |
Aliases
for OAS3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| 2'-5'-Oligoadenylate Synthetase 3, 100kDa1 2 | | 2'-5'-Oligoadenylate Synthase 32 | | (2-5')Oligo(A) Synthase 32 3 | | 2'-5'Oligoadenylate Synthetase P1002 | | 2-5A Synthase 32 3 | | 2-5A Synthetase 32 | | P100 OAS2 3 | | P1001 | | P100OAS1 | | EC 2.7.7.-3 | | 2'-5'-Oligoadenylate Synthetase 3 (100 KD)1 | | EC 2.7.78 | | (2-5')Oligo(A) Synthetase 32 | | |
Export aliases for OAS3 gene to outside databasesPrevious GC identifers: GC12P112271 GC12P112895 GC12P113159 GC12P111788 GC12P111838 GC12P110388 |
Summaries
for OAS3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OAS3:
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced byinterferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme familyplays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: OAS3_HUMAN, Q9Y6K5Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviralresponse. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth,differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP whichthen bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequentactivation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibitionof protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNaseL-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity againstChikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV)
Gene Wiki entry for OAS3
|
Genomic Views
for OAS3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OAS3 gene promoter:
HEN1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for OAS3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OAS3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.2 Ensembl cytogenetic band: 12q24.13 HGNC cytogenetic band: 12q24.2OAS3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P113376: view genomic region
(about GC identifiers)
Start:
|
113,376,157 bp from pter |
End:
|
113,411,054 bp from pter |
Size:
|
34,898 bases |
Orientation:
|
plus strand |
|
Proteins
for OAS3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: OAS3_HUMAN, Q9Y6K5 (See
protein sequence)Recommended Name: 2'-5'-oligoadenylate synthase 3 Size: 1087 amino acids; 121170 Da
Cofactor: Magnesium (Potential)
Subunit: Monomer
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=AAD28543.1; Type=Frameshift; Positions=394, 398;
Secondary accessions: Q2HJ14 Q9H3P5Explore the universe of human proteins at neXtProt for OAS3: NX_Q9Y6K5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y6K5
3 DME Specific Peptides for OAS3 (Q9Y6K5)
OAS3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006178.2
ENSEMBL proteins: ENSP00000228928 ENSP00000449299 ENSP00000448388 ENSP00000447323 ENSP00000449851 Reactome Protein details: Q9Y6K5
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
OAS3 for ontologies About GeneDecksing
OAS3 Antibody Products:
Assay Products for OAS3: |
Protein
Domains /
Families
for OAS3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OAS3 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y6K5ProtoNet protein and cluster: Q9Y6K5 2 Blocks protein families: IPB002934 DNA polymerase IPB006117 2-5-oligoadenylate synthetase
UniProtKB/Swiss-Prot: OAS3_HUMAN, Q9Y6K5Similarity: Belongs to the 2-5A synthase family |
Function
for OAS3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: OAS3_HUMAN, Q9Y6K5Function: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviralresponse. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth,differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP whichthen bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequentactivation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibitionof protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNaseL-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity againstChikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV)Catalytic activity: Binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate thelatent RNase L that, when activated, cleaves single-stranded RNAsEnzyme regulation: Produced as a latent enzyme which is activated by dsRNA generated during the course of viralinfection. The dsRNA activator must be at least 15 nucleotides long, and no modification of the 2'-hydroxyl group istolerated. ssRNA or dsDNA do not act as activatorsInduction: By type I interferon (IFN) and viruses Genatlas biochemistry entry for OAS3:2',5'-oligoadenylate synthetase 3,100kDa,ubiquitously expressed ,interferon induced
Enzyme Numbers (IUBMB): EC 2.7.7.-1 EC 2.7.72
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for OAS3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OAS3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OAS3 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
OAS3 for ontologies About GeneDecksing
|
Pathways & Interactions
for OAS3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Expression of IFN-induced genes | | | 2 | Interferon gamma signaling | | | 3 | Measles | | | 4 | Cytokine Signaling in Immune system | | | 5 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 
Reactome Pathways for OAS3 (see all 7)
3 
Kegg Pathways (Kegg details for OAS3):
OAS3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OAS3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/67 Interacting proteins for OAS3 (Q9Y6K51, 3 ENSP000002289284) via UniProtKB, MINT, STRING, and/or I2D (see all 67)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| IFRD2 | Q128941, 3, ENSP000003989714 | EBI-6115729,EBI-6115935 I2D:
score=1 STRING: ENSP00000398971 | | FTSJ3 | Q8IY811, 3 | EBI-6115729,EBI-744088 I2D:
score=1 | | DHX30 | Q7L2E31, 3, ENSP000003926014 | EBI-6115729,EBI-1211456 I2D:
score=1 STRING: ENSP00000392601 | | EIF6 | P565371, 3, ENSP000003635594 | EBI-6115729,EBI-372243 I2D:
score=1 STRING: ENSP00000363559 | | MAVS | Q7Z4341, 3, ENSP000004019804 | EBI-6115729,EBI-995373 I2D:
score=1 STRING: ENSP00000401980 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
OAS3 for ontologies About GeneDecksing
|
Drugs & Compounds
for OAS3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
OAS3 for compounds About GeneDecksing
 Browse Tocris compounds for OAS3
1 HMDB Compound for OAS3 About this table
1 Novoseek chemical compound relationship for OAS3 gene About this table
Search CenterWatch for drugs/clinical trials and news about OAS3
|
Transcripts
for OAS3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OAS3 gene: NM_006187.2 Unigene Cluster for OAS3: 2'-5'-oligoadenylate synthetase 3, 100kDa Hs.744211 [show with all ESTs]Unigene Representative Sequence: AB0445457 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000228928(uc001tug.3) ENST00000551007(uc001tue.3) ENST00000548514(uc001tuf.3)
ENST00000546638 ENST00000546800 ENST00000546973 ENST00000549918
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: OAS3 (NM_006187) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OAS3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OAS3 |
Additional cDNA sequence: AB044545.1 AF063613.1 AK000608.1 AK292949.1 BC113746.1 9 DOTS entries: DT.211616 DT.436928 DT.121211619 DT.100792978 DT.87016758 DT.100721041 DT.40275249 DT.91679771 DT.91872112 24/277 AceView cDNA sequences (see all 277): AA312111 BU145349 BM977099 BU860096 AI124829 NM_006187 BU169707 BU857070 BU956028 CB123126 BU944625 BG390192 BM836505 BM471312 BU539624 BM806155 BQ279127 CA455330 CR602049 AI738921 BQ430582 BU956885 BU902141 BC012015
GeneLoc Exon Structure
|
Expression
for OAS3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OAS3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGCTGGTAC
About this image
See OAS3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OAS3
SOURCE GeneReport for Unigene cluster: Hs.744211
UniProtKB/Swiss-Prot: OAS3_HUMAN, Q9Y6K5Tissue specificity: Present at high level in placenta trophoblast
SABiosciences Custom PCR Arrays for OAS3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OAS3
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OAS3 |
Orthologs
for OAS3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for OAS3 (if available)
TreeFam Gene Tree for OAS3 (if available) |
Paralogs
for OAS3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for OAS3 gene
- OAS22 OASL2 OAS12
4 SIMAP similar genes for OAS3 using alignment to 6 protein entries: OAS3_HUMAN (see all proteins):OAS1 OASL OAS2 OASLd
OAS3 for paralogs About GeneDecksing
|
Genomic Variants
for OAS3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OAS3 (113376157 - 113411054 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for OAS3
1 Indel: 48944 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OAS3 |
|
Disorders
/ Diseases
for OAS3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OAS3 for disorders About GeneDecksing
OMIM gene information: 603351
OMIM disorders: --
17  diseases for OAS3: About MalaCardstick-borne encephalitis west nile encephalitis dengue hemorrhagic fever hemorrhagic fever
chikungunya encephalitis hepatitis c hepatitis b
measles cervical cancer cervicitis ovarian cancer
hepatitis influenza pancreatic cancer pancreatitis
alcoholism
2 diseases from the University of Copenhagen DISEASES database for OAS3:West Nile encephalitis tick-borne encephalitis Genetic Association Database (GAD): OAS3
Human Genome Epidemiology (HuGE) Navigator: OAS3 (9 documents)
Export disorders for OAS3 gene to outside databases
|
Publications
for OAS3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OAS3 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with OAS3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus. (PubMed id 19056102)1, 2, 9 BrAchin A.C....DesprA"s P. (2009)
- Distinct antiviral roles for human 2',5'-oligoadenyla te synthetase family members against dengue virus infection. (PubMed id 19923450)1, 2, 9 Lin R.J....Lin Y.L. (2009)
- Characterization of the gene encoding the 100-kDa form of human 2', 5'oligoadenylate synthetase. (PubMed id 11112351)1, 2, 9 Rebouillat D....Williams B.R. (2000)
- Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype? (PubMed id 16014697)1, 4, 9 Tessier M.C....Polychronakos C. (2006)
- The human 2'-5'oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation. (PubMed id 17408844)1, 2 Hovanessian A.G. and Justesen J. (2007)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (2006)
- Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study. (PubMed id 12447867)1, 4 King J.K....Chen P.J. (2002)
- Molecular basis of T cell-mediated recognition of pancreatic cancer cells. (PubMed id 11280764)1, 2 Ito M....Itoh K. (2001)
- The 100-kDa 2',5'-oligoadenylate synthetase catalyzing preferentially the synthesis of dimeric pppA2'p5'A molecules is composed of three homologous domains. (PubMed id 9880533)1, 2 Rebouillat D.... Hovanessian A.G. (1999)
- The human 2',5'-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms. (PubMed id 9790745)1, 3 Hovnanian A....Hovanessian A.G. (1998)
|
External Searches for OAS3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OAS3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OAS3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OAS3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OAS3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for OAS3 gene:
Search GeneIP for patents involving OAS3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OAS3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for OAS3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OAS3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OAS3 | | | OriGene Protein Over-expression Lysate for OAS3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OAS3 | | OriGene 3'-UTR Clone for OAS3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OAS3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OAS3 | | OriGene Custom Protein Services for OAS3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OAS3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OAS3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OAS3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OAS3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OAS3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OAS3 |
| |
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| | | | Search Tocris compounds for OAS3 |
| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OAS3 |
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