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NET1 Gene

protein-coding GIFtS: 63

GC10P005444

neuroepithelial cell transforming 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ARHGEF8 ^¹, ², ³
NAT1 ^⁵
NET1A ^¹, ²
OTTHUMP00000019002 ^²
OTTHUMP00000019003 ^²
SLC6A2 ^⁵

Descriptions
Rho guanine nucleotide exchange factor (GEF) 8 ^²
Rho guanine nucleotide exchange factor 8 ^³
guanine nucleotide regulatory protein (oncogene) ^²
neuroepithelial cell transforming 1 ^²
neuroepithelial cell transforming gene 1 ^²
neuroepithelioma transforming gene 1 ^²
p65 Net1 proto-oncogene ^³
p65 Net1 proto-oncogene protein ^²
small GTP-binding protein regulator ^²

External Ids
HGNC: 14592¹
Entrez Gene: 10276²
UniProtKB: Q7Z628³
Ensembl: ENSG00000173848⁷

Search outside databases for aliases for NET1 gene

Previous GC identifers: GC10M005513 GC10P005428 GC10P005554 GC10P005408

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ARHG8_HUMAN, Q7Z628

Function: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in

activation of the SAPK/JNK pathway (By similarity)

Gene Wiki entry for NET1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NET1 gene

Entrez Gene cytogenetic band: 10p15 Ensembl cytogenetic band: 10p15.1 HGNC cytogenetic band: 10p15

NET1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P005444: (about GC identifiers)

Start:	5,444,518 bp from pter
End:	5,490,426 bp from pter
Size:	45,909 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000010.9 NT_077567.3

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ARHG8_HUMAN, Q7Z628 (See protein sequence)

Recommended Name: Neuroepithelial cell-transforming gene 1 protein

Size: 596 amino acids; 67740 Da

Subunit: Interacts with RHOA in its GTP- and GDP-bound states, and with CDC42 in its GTP-bound

state. Interacts with the PDZ 1 domain of BAIAP1 (By similarity)

Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)

Sequence caution: Sequence=AAB08847.1; Type=Frameshift; Positions=586; Sequence=AAB37683.1;

Type=Frameshift; Positions=15, 33; Sequence=CAA08974.1; Type=Frameshift; Positions=8, 55, 59, 70,

586;

PDB structures from and Proteopedia :

3EO2 (3D)

Secondary accessions: Q12773 Q96D82 Q99903 Q9UEN6

Alternative splicing: 2 isoforms: Q7Z628-1 Q7Z628-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001040625.1 NP_005854.2

ENSEMBL proteins:

ENSP00000369694 ENSP00000369717 ENSP00000347134

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (NET1)
	Human Recombinant Proteins from Abnova (NET1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--
GO:0005622	intracellular	IEA	--
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for NET1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (NET1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (NET1)
	Novus Biologicals Antibodies for NET1

Assays for NET1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q7Z628

ProtoNet protein and cluster: Q7Z628

2 Blocks protein families:

IPB000219 DH domain

IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: ARHG8_HUMAN, Q7Z628

Similarity: Contains 1 DH (DBL-homology) domain

Similarity: Contains 1 PH domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NET1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001047160

Applied Biosystems Silencer® siRNAs for NET1

Sigma-Aldrich siRNA for NET1

Sigma-Aldrich shRNA for NET1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for NET1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001047160
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001047160
untagged cDNA clones in CMV expression vector (see all 3): NM_001047160

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001047160

UniProtKB/Swiss-Prot: ARHG8_HUMAN, Q7Z628

Function: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in

activation of the SAPK/JNK pathway (By similarity)

Induction: By TGF-beta

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005085	guanyl-nucleotide exchange factor activity	TAS	8649828
GO:0005089	Rho guanyl-nucleotide exchange factor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for NET1

5/81 Interacting proteins for NET1 (ENSP00000347134³) via UniProtKB, MINT, and/or STRING (see all 81 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
A2M	ENSP00000323929³	STRING (score=.899)
ABR	ENSP00000303909³	STRING (score=.899)
ARAP1	ENSP00000352332³	STRING (score=.899)
ARAP3	ENSP00000239440³	STRING (score=.899)
ARHGAP1	ENSP00000310491³	STRING (score=.899)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001558	regulation of cell growth	NAS	8649828
GO:0007242	intracellular signaling cascade	IEA	--
GO:0035023	regulation of Rho protein signal transduction	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NET1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NET1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001047160

Sigma-Aldrich siRNA for NET1

Sigma-Aldrich shRNA for NET1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001047160 NM_005863

REFSEQ mRNAs for NET1 gene (2 alternative transcripts):

NM_001047160.1 NM_005863.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001047160 NM_005863

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001047160
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001047160
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001047160

Additional cDNA sequence:

AB209852.1 AJ010046.1 AK024919.1 AK294244.1 AK299335.1 AK302687.1 AK304028.1 AK315566.1

BC010285.1 BC053553.1 S82401.1 U02081.1

18 DOTS entries:

DT.97860210 DT.455207 DT.86838054 DT.100792472 DT.99991536 DT.455206 DT.97810157 DT.121221194

DT.95301494 DT.102826903 DT.121221244 DT.40279022 DT.92447449 DT.121221239 DT.121221261 DT.92384021

DT.97860209 DT.447089

24/386 AceView cDNA sequences (see all 386 ):

AI610995 CA391308 BQ181013 CB851085 BP376957 AI886132 AU130957 AW771003

BE645597 CA392582 BM802639 AA630998 BQ024362 AW675637 CA489179 CB119951

BM771515 AA025841 AU125526 BG770848 AU280423 AA831287 BG675849 CK429832

highest scoring ESTs for NET1:

AJ010046 AA025841 AA025842 AA039870 AA040233 AA042891 AA062769 AA074082 AA082428 AA196448

Unigene Cluster for NET1:

Neuroepithelial cell transforming 1

Hs.25155 [show with all ESTs]

Unigene Representative Sequence: NM_001047160

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for NET1 (see all 10 )

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b	·	8c	^	9a	·	9b	^	10	^	11a	·	11b	^	12	^	13a	·	13b	^	14
SP1:											-		-						-				-		-																				-
SP2:																			-				-		-																				-
SP3:											-		-						-				-
SP4:													-
SP5:																																													-

About this scheme

ECgene alternative splicing isoforms for NET1

3 Ensembl transcripts including schematic representations:

ENST00000380337 ENST00000380359 ENST00000355029

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NET1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NET1

¹ / ² / ³

5 probe-sets matching NET1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33894_at²^{, 3}	U95-A	1	0.31	1.00	1.00	1.00	AJ010046	1.00	1.00	1.00	1
201830_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005863	0.60	1.00	0.82	1
201829_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AW263232	0.80	1.00	0.91	1
201830_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201829_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AAATGGCTTG

SOURCE GeneReport for Unigene cluster: Hs.25155
Expression variation in blood from EXPOLDB for NET1
UniProtKB/Swiss-Prot: ARHG8_HUMAN, Q7Z628
Tissue specificity: Widely expressed

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NET1 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NET1¹	--	neuroepithelial cell transforming gene 1	84.56(n) 85.82(a)	487147 XM_544275.2 XP_544275.2
chimpanzee (Pan troglodytes)	NET1¹	--	neuroepithelial cell transforming gene 1	99.27(n) 99.33(a)	450277 XM_507633.2 XP_507633.2
cow (Bos taurus)	NET1¹	--	neuroepithelial cell transforming gene 1	81.52(n) 81.64(a)	507365 NM_001034296.1 NP_001029468.1
rat (Rattus norvegicus)	Net1¹	--	neuroepithelial cell transforming 1	83.08(n) 85.04(a)	307098 NM_001039023.1 NP_001034112.1
mouse (Mus musculus)	Net1^{1, 5}	13⁵	neuroepithelial cell transforming gene 1^{1, 5}	85.32(n)¹ 87.06(a)¹	56349¹ NM_019671.2¹ NP_062645.2¹ AF094520⁵ AI604373⁵ (see all 21)

About this table Species with no ortholog for NET1

ENSEMBL Gene Tree for NET1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for NET1 gene

ARHGEF3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/318 NCBI SNPs in NET1 are shown (see all 318 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 54)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs11791^1,2	A,C,F,H	5489173(+)	`CTTGAG/ATTATT`	2	--	ut3¹		6		MN EU EA WA	790
	rs7090012^1,2	A,C,F,H	5478580(+)	`AGCCTC/GTGCTC`	2	--	int¹ ut5¹ ese³		7		EU EA WA NA	510
	rs7068596^1,2	A,C,F,H	5477530(+)	`CTACCA/GTCATA`	2	--	ng5¹ int¹		7		EU EA WA NA	542
	rs4466726^1,2	C,F,H	5477141(-)	`CTGAGG/ATCACG`	2	--	int¹ ng5¹		7		EU EA WA NA	532
	rs7076318^1,2	A,C,F	5478085(+)	`GCTAGT/CCTTAA`	2	--	ng5¹ int¹		6		EA NA MN	572
	rs7087584^1,2	C,F,H	5490159(+)	`ATTTTG/CGTGGA`	2	--	ut3¹		4		EU EA WA	402
--	rs6601972^1,2	A,C	5489705(+)	`TATATA/TTTTTT`	2	--	ut3¹ ese³		0	--	--	--	--
	rs34658946^1,2	C,F	5488102(-)	`TCCGTG/ATGACG`	2	I/T	mis¹		5		NA EU EA WA	498
	rs11253181^1,2	F,H	5476887(+)	`TTTGCA/CCTAAC`	2	--	int¹ ng5¹		4		EU EA WA	384
--	rs10795275^1,2	A,C	5444458(+)	`ACTCCA/GCGTCT`	1	--	ng5¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for NET1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 163970 disorders: 604715

1 Novoseek disease relationship for NET1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neuroepithelioma	88.00	3	15611121 (1), 19124484 (1), 8649828 (1)

About this table

Genetic Association Database: NET1
Human Genome Epidemiology Navigator: NET1 (60 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/27 PubMed articles for NET1 gene (see all 27 ):

Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning. (PubMed id 8649828)^{1, 2, 3, 4} Chan A.M.-L.... Miki T. (1996)
Support for association between ADHD and two candidate genes: NET1 and DRD1. (PubMed id 15717291)^{3, 6} Bobb A.J....Rapoport J.L. (2005)
DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association. (PubMed id 15719398)^{3, 6} Xu X....Asherson P. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation. (PubMed id 11278519)^{3, 4} Shen X.... Wang X.-F. (2001)
Expression and clinical significance of NET-1 and PCNA in hepatocellular carcinoma. (PubMed id 18214716)^{1, 3} Shen S.Q....Nakao A. (2008)
Characterization of the biochemical and transforming properties of the neuroepithelial transforming protein 1. (PubMed id 15611121)^{1, 3} Qin H....Frost J.A. (2005)
The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity. (PubMed id 17938206)^{1, 3} Garcia-Mata R....Burridge K. (2007)
Coexpression of alpha6beta4 integrin and guanine nucleotide exchange factor Net1 identifies node-positive breast cancer patients at high risk for distant metastasis. (PubMed id 19124484)^{1, 3} Gilcrease M.Z....Frost J.A. (2009)
A bacterial cytotoxin identifies the RhoA exchange factor Net1 as a key effector in the response to DNA damage. (PubMed id 18509476)^{1, 3} Guerra L....Frisan T. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10276	HGNC: 14592	AceView: NET1	Ensembl:ENSG00000173848	euGenes: HUgn10276
ECgene: NET1	H-InvDB: NET1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for NET1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for NET1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for NET1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NET1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NET1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NET1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (NET1)
	Antibodies (NET1)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (NET1)
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Search OriGene for NET1

Search Tocris compounds for NET1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for NET1

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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NET1 Gene at Home site.
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NET1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for NET1

Summaries
for NET1

Genomic Location
for NET1

Proteins
for NET1

Protein Domains/
Families
for NET1

Gene Function
for NET1

Pathways & Interactions
for NET1

Drugs & Compounds
for NET1

Transcripts
for NET1

Expression
for NET1

Orthologs
for NET1

Paralogs
for NET1

SNPs/Variants
for NET1

Disorders & Mutations
for NET1

Medical News
for NET1

Publications
for NET1

Search for NET1

Genome Databases showing NET1

Other Databases showing NET1

Specialized Databases showing NET1

Licensable Technologies
for NET1

Services
for NET1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NET1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor NET1

Summariesfor NET1

Genomic Locationfor NET1

Proteinsfor NET1

Protein Domains/Familiesfor NET1

Gene Functionfor NET1

Pathways & Interactionsfor NET1

Drugs & Compoundsfor NET1

Transcriptsfor NET1

Expression for NET1

Orthologsfor NET1

Paralogsfor NET1

SNPs/Variantsfor NET1

Disorders & Mutationsfor NET1

Medical Newsfor NET1

Publicationsfor NET1

Search for NET1

Genome Databases showing NET1

Other Databases showing NET1

Specialized Databases showing NET1

Licensable Technologiesfor NET1

Servicesfor NET1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NET1

Summaries
for NET1

Genomic Location
for NET1

Proteins
for NET1

Protein Domains/
Families
for NET1

Gene Function
for NET1

Pathways & Interactions
for NET1

Drugs & Compounds
for NET1

Transcripts
for NET1

Expression
for NET1

Orthologs
for NET1

Paralogs
for NET1

SNPs/Variants
for NET1

Disorders & Mutations
for NET1

Medical News
for NET1

Publications
for NET1

Licensable Technologies
for NET1

Services
for NET1