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NYNRIN Gene

protein-coding   GIFtS: 46
GCID: GC14P024868

NYN Domain And Retroviral Integrase Containing

(Previous name: KIAA1305)
(Previous symbol: KIAA1305)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NYN Domain And Retroviral Integrase Containing1 2     CGIN12 3
KIAA13051 2 3     NYN Domain And Retroviral Integrase Catalytic Domain-Containing Protein2 3
Cousin Of GIN11 2     Protein NYNRIN2
Protein Cousin Of GIN12 3     

External Ids:    HGNC: 201651   Entrez Gene: 575232   Ensembl: ENSG000002059787   UniProtKB: Q9P2P13   

Export aliases for NYNRIN gene to outside databases

Previous GC identifers: GC14P023938 GC14P004982


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NYNRIN Gene:
NYNRIN (NYN domain and retroviral integrase containing) is a protein-coding gene. Diseases associated with NYNRIN include ataxia. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZC3H12C.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NYNRIN
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NYNRIN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NYNRIN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q11.2

NYNRIN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NYNRIN gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P024868:  view genomic region     (about GC identifiers)

Start:
24,867,992 bp from pter      End:
24,888,494 bp from pter
Size:
20,503 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NYNRI_HUMAN, Q9P2P1 (See protein sequence)
Recommended Name: Protein NYNRIN  
Size: 1898 amino acids; 208366 Da
Miscellaneous: The gene encoding this protein may have arisen from the fusion of a cellular gene with retroviral
sequences prior to the marsupial-eutherian split. Sequence and structural analyses suggest that the integrase
catalytic domain is inactive
Sequence caution: Sequence=AAH65283.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q6P153 Q86TR3 Q9HAC4
Alternative splicing: 2 isoforms:  Q9P2P1-1   Q9P2P1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NYNRIN: NX_Q9P2P1

Explore proteomics data for NYNRIN at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NYNRIN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079357.2  
    ENSEMBL proteins: 
     ENSP00000371994  

    NYNRIN Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for NYNRIN

    NYNRIN Antibody Products:

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    OriGene Custom Antibody Services for NYNRIN
    Novus Biologicals NYNRIN Antibody
    Abcam antibodies for NYNRIN
    Cloud-Clone Corp. Antibodies for NYNRIN
    Search ThermoFisher Antibodies for NYNRIN
    Search LSBio for Antibodies for NYNRIN

    NYNRIN Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NYNRIN
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NYNRIN
    Cloud-Clone Corp. CLIAs for NYNRIN


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR001584 Integrase_cat-core
     IPR021869 RNase_Zc3h12
     IPR012337 RNaseH-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9P2P1

    ProtoNet protein and cluster: Q9P2P1

    1 Blocks protein domain: IPB001584 Integrase

    UniProtKB/Swiss-Prot: NYNRI_HUMAN, Q9P2P1
    Similarity: Contains 1 integrase catalytic domain


    NYNRIN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003676nucleic acid binding IEA--
         
    NYNRIN for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NYNRIN:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NYNRIN
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NYNRIN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NYNRIN

    miRNA
    Products:
        
    miRTarBase miRNAs that target NYNRIN:
    hsa-mir-484 (MIRT042292)

    Block miRNA regulation of human, mouse, rat NYNRIN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NYNRIN (see all 35):
    hsa-miR-3164 hsa-let-7d hsa-miR-15a hsa-miR-503 hsa-miR-486-3p hsa-let-7g hsa-miR-124 hsa-miR-424
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NYNRIN
    Predesigned siRNA for gene silencing in human, mouse, rat NYNRIN

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NYNRIN

    Clone
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    OriGene clones in human, mouse for NYNRIN (see all 5)
    OriGene ORF clones in mouse, rat for NYNRIN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NYNRIN (NM_025081)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NYNRIN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NYNRIN

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for NYNRIN 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NYNRIN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NYNRI_HUMAN, Q9P2P1: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    golgi apparatus1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0016021integral component of membrane IEA--

    NYNRIN for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NYNRIN
    Interactions:

        Search GeneGlobe Interaction Network for NYNRIN

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for NYNRIN (Q9P2P12, 3 ENSP000003719944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGTPBP1Q9UPW52, 3, ENSP000003385124MINT-2875141 I2D: score=3 STRING: ENSP00000338512
    CCDC115ENSP000002592294STRING: ENSP00000259229
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0015074DNA integration IEA--

    NYNRIN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NYNRIN (NYNRI)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NYNRIN gene: 
    NM_025081.2  

    Unigene Cluster for NYNRIN:

    NYN domain and retroviral integrase containing
    Hs.288348  [show with all ESTs]
    Unigene Representative Sequence: NM_025081
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000382554(uc001wpf.4) ENST00000554505
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NYNRIN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NYNRIN (see all 35):
    hsa-miR-3164 hsa-let-7d hsa-miR-15a hsa-miR-503 hsa-miR-486-3p hsa-let-7g hsa-miR-124 hsa-miR-424
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NYNRIN
    Predesigned siRNA for gene silencing in human, mouse, rat NYNRIN
    Clone
    Products:
         
    OriGene clones in human, mouse for NYNRIN (see all 5)
    OriGene ORF clones in mouse, rat for NYNRIN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NYNRIN (NM_025081)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NYNRIN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NYNRIN
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NYNRIN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NYNRIN
      QuantiTect SYBR Green Assays in human, mouse, rat NYNRIN
      QuantiFast Probe-based Assays in human, mouse, rat NYNRIN

    Additional mRNA sequence: 

    AB037726.2 AK021873.1 BC008219.1 BC065283.1 BX248773.1 

    4 DOTS entries:

    DT.212215  DT.100695763  DT.100775313  DT.97825991 

    Selected AceView cDNA sequences (see all 78):

    AA904759 BU741587 BU553982 C00733 BF820756 CR596800 BF820599 BF928021 
    AB037726 BX248773 BM721221 BQ002746 AA411382 AA406197 AA639626 T51307 
    AK021873 BE867659 CB134017 BC008219 CB133315 AI914740 AA410712 BM971859 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NYNRIN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAGGGTTC
    NYNRIN Expression
    About this image


    NYNRIN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Testicular Interstitial Cells Testis Interstitium
    NYNRIN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NYNRIN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.288348
        Custom PCR Arrays for NYNRIN
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NYNRIN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NYNRIN
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NYNRIN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NYNRIN gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nynrin1 , 5 NYN domain and retroviral integrase containing1, 5 81.63(n)1
    78.15(a)1
      14 (28.19 cM)5
    2771541  NM_001040072.11  NP_001035161.11 
     558541155 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    27(a)
    1 → many
    GL343220.1(751412-765283)
    zebrafish
    (Danio rerio)
    Actinopterygii KHNYN6
    KH and NYN domain containing
    25(a)
    1 → many
    7(1506079-1534415) ENSDARG00000092488
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108896
    --
    23(a)
    1 → many
    3R(15859603-15861777)
    worm
    (Caenorhabditis elegans)
    Secernentea C30F12.16
    Protein C30F12.1 (C30F12.1) mRNA, complete cds
    17(a)
    1 → many
    I(6954411-6961139) WBGene00016260


    ENSEMBL Gene Tree for NYNRIN (if available)
    TreeFam Gene Tree for NYNRIN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NYNRIN gene
    ZC3H12C2  N4BP12  ZC3H12B2  ZC3H12D2  KHNYN2  ZC3H12A2  

    NYNRIN for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NYNRIN (see all 575)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs758602221,2
    F--24866041(+) TTCTTC/ATTCCT 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1468202791,2
    --24866134(+) AATACA/GTGTTA 1 -- us2k10--------
    rs1810330311,2
    C--24866155(+) ATAAGC/TGAATG 1 -- us2k10--------
    rs1859204181,2
    --24866169(+) TTGGTC/TCTATG 1 -- us2k10--------
    rs1919743041,2
    --24866201(+) CCATGC/GAGTTC 1 -- us2k10--------
    rs1132561741,2
    F--24866414(+) GAAGAG/AACAAG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1831321471,2
    --24866493(+) CATGTA/TGTCTG 1 -- us2k10--------
    rs755208931,2
    C,F--24866544(+) ATGAGC/TTAAAG 1 -- us2k13Minor allele frequency- T:0.06CSA WA NA 240
    rs574376631,2
    C,F--24866685(+) CATGAA/GGATGA 1 -- us2k15Minor allele frequency- G:0.13NA CSA WA EA 362
    rs1456256891,2
    C--24866710(+) GTTCAC/TGGTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NYNRIN (24867992 - 24888494 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NYNRIN: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NYNRIN
    DNA2.0 Custom Variant and Variant Library Synthesis for NYNRIN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for NYNRIN:    
    About MalaCards
    ataxia


    NYNRIN for disorders           About GeneDecksing

    Genetic Association Database (GAD): NYNRIN

    Export disorders for NYNRIN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NYNRIN gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with NYNRIN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Biological, clinical and population relevance of 95 loci for blood lipids. (PubMed id 20686565)1, 4 Teslovich T.M....Kathiresan S. (Nature 2010)
    2. CGIN1: a retroviral contribution to mammalian genomes. (PubMed id 19561090)1, 3 Marco A. and MarA-n I. (Mol. Biol. Evol. 2009)
    3. The NYN domains: novel predicted RNAses with a PIN domain-like fold. (PubMed id 17114934)1, 3 Anantharaman V. and Aravind L. (RNA Biol 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    6. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    7. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (Cell 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57523 HGNC: 20165 AceView: KIAA1305 Ensembl:ENSG00000205978 euGenes: HUgn57523
    ECgene: NYNRIN H-InvDB: NYNRIN

    (According to HUGE)
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    HUGE: KIAA1305

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NYNRIN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NYNRIN gene:
    Search GeneIP for patents involving NYNRIN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NYNRIN  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
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     OriGene Custom Antibody Services for NYNRIN   OriGene Custom Protein Services for NYNRIN  

     
     
     Block miRNA regulation of human, mouse, rat NYNRIN using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NYNRIN
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NYNRIN Predesigned siRNA for gene silencing in human, mouse, rat NYNRIN
     QuantiFast Probe-based Assays in human, mouse, rat NYNRIN QuantiTect SYBR Green Assays in human, mouse, rat NYNRIN
     Custom PCR Arrays for NYNRIN Search Chromatin IP Primers for NYNRIN
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     GenScript Custom Purified and Recombinant Proteins Services for NYNRIN GenScript cDNA clones with any tag delivered in your preferred vector for NYNRIN
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for NYNRIN (NYNRI)
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     Browse ESI BIO Cell Lines and PureStem Progenitors for NYNRIN
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     Search ThermoFisher Antibodies for NYNRIN
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NYNRIN
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NYNRIN
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NYNRIN
     Search LSBio for Antibodies for NYNRIN
    Customized transgenic rodents for:
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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