Aliases for NXT2 Gene
External Ids for NXT2 Gene
Previous GeneCards Identifiers for NXT2 Gene
The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for NXT2 Gene
NXT2 (Nuclear Transport Factor 2 Like Export Factor 2) is a Protein Coding gene. Diseases associated with NXT2 include Non-Syndromic X-Linked Intellectual Disability. Among its related pathways are RNA transport and Ribosome biogenesis in eukaryotes. An important paralog of this gene is NXT1.
UniProtKB/Swiss-Prot for NXT2 Gene
Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export.