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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NXPH4 Gene

protein-coding   GIFtS: 49
GCID: GC12P057610

Neurexophilin 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neurexophilin 41 2
NPH42 3
neurexophilin-42

External Ids:    HGNC: 80781   Entrez Gene: 112472   Ensembl: ENSG000001823797   OMIM: 6046375   UniProtKB: O951583   

Export aliases for NXPH4 gene to outside databases

Previous GC identifers: GC00U990505 GC12U900046 GC12P057327 GC12P055896 GC12P054657


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NXPH4 Gene: 
NXPH4 (neurexophilin 4) is a protein-coding gene. Diseases associated with NXPH4 include otitis externa, and cystic kidney. GO annotations related to this gene include molecular_function. An important paralog of this gene is NXPH1.

UniProtKB/Swiss-Prot: NXPH4_HUMAN, O95158
Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and
possibly other receptors (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NXPH4 gene promoter:
         E2F-3a   E2F-4   Sp1   E2F   E2F-1   E2F-2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNXPH4 promoter sequence
   Search SABiosciences Chromatin IP Primers for NXPH4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NXPH4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.3   Ensembl cytogenetic band:  12q13.3   HGNC cytogenetic band: 12q13

NXPH4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NXPH4 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P057610:  view genomic region     (about GC identifiers)

Start:
57,610,578 bp from pter      End:
57,620,232 bp from pter
Size:
9,655 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NXPH4_HUMAN, O95158 (See protein sequence)
Recommended Name: Neurexophilin-4 precursor  
Size: 308 amino acids; 33065 Da
Subcellular location: Secreted (Potential)
Secondary accessions: A8K4I4 Q7Z6L3 Q8N462

Explore the universe of human proteins at neXtProt for NXPH4: NX_O95158

Explore proteomics data for NXPH4 at MOPED 

Post-translational modifications:

  • UniProtKB: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved
    domain in neuron-like cells (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95158

  • NXPH4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NXPH4 Protein Expression
    REFSEQ proteins: NP_009155.1  
    ENSEMBL proteins: 
     ENSP00000333593   ENSP00000452288  

    Human Recombinant Protein Products for NXPH4: 
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    OriGene Protein Over-expression Lysate for NXPH4
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NXPH4
    GenScript Custom Purified and Recombinant Proteins Services for NXPH4
    Novus Biologicals NXPH4 Proteins
    Novus Biologicals NXPH4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NXPH4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005576extracellular region IEA--

    NXPH4 for ontologies           About GeneDecksing



    NXPH4 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for NXPH4 

    Assay Products for NXPH4: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NXPH4 
    Cloud-Clone Corp. CLIAs for NXPH4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR010450 Neurexophilin
     IPR026845 NXPH/NXPE

    Graphical View of Domain Structure for InterPro Entry O95158

    ProtoNet protein and cluster: O95158

    1 Blocks protein domain: IPB010450 Neurexophilin

    UniProtKB/Swiss-Prot: NXPH4_HUMAN, O95158
    Similarity: Belongs to the neurexophilin family


    NXPH4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NXPH4_HUMAN, O95158
    Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and
    possibly other receptors (Potential)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    NXPH4 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NXPH4:
     Decreased homologous recombina  Decreased viability of wild-ty 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Nxph4):
     homeostasis/metabolism  no phenotypic analysis  renal/urinary system 

    NXPH4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nxph4tm1Lex for NXPH4

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NXPH4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NXPH4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NXPH4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NXPH4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NXPH4
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate NXPH4 (see all 9):
    hsa-miR-1290 hsa-miR-623 hsa-miR-876-5p hsa-miR-3167 hsa-miR-211 hsa-miR-3916 hsa-miR-3125 hsa-miR-204
    SwitchGear 3'UTR luciferase reporter plasmidNXPH4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NXPH4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NXPH4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NXPH4
    Sirion Biotech Customized adenovirus for overexpression of NXPH4

    Clone
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    OriGene clones in human, mouse for NXPH4 (see all 7)
    OriGene ORF clones in mouse, rat for NXPH4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NXPH4 (NM_007224)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NXPH4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NXPH4
    Sirion Biotech Customized lentivirus for stable overexpression of NXPH4 
                         Customized lentivirus expression plasmids for stable overexpression of NXPH4 

    Cell Line
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    Search LifeMap BioReagents cell lines for NXPH4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXPH4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NXPH4

    1 Interacting protein for NXPH4 (O951583) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TECPR1Q7Z6L13I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007218neuropeptide signaling pathway NAS9570794

    NXPH4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NXPH4

    Search CenterWatch for drugs/clinical trials and news about NXPH4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NXPH4 gene: 
    NM_007224.3  

    Unigene Cluster for NXPH4:

    Neurexophilin 4
    Hs.745023  [show with all ESTs]
    Unigene Representative Sequence: AK094231
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000349394(uc010srf.2) ENST00000556415(uc009zpj.3) ENST00000555154

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NXPH4
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate NXPH4 (see all 9):
    hsa-miR-1290 hsa-miR-623 hsa-miR-876-5p hsa-miR-3167 hsa-miR-211 hsa-miR-3916 hsa-miR-3125 hsa-miR-204
    SwitchGear 3'UTR luciferase reporter plasmidNXPH4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NXPH4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NXPH4
    Clone
    Products:
         
    OriGene clones in human, mouse for NXPH4 (see all 7)
    OriGene ORF clones in mouse, rat for NXPH4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NXPH4 (NM_007224)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NXPH4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NXPH4
    Sirion Biotech Customized lentivirus for stable overexpression of NXPH4 
                         Customized lentivirus expression plasmids for stable overexpression of NXPH4 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NXPH4
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NXPH4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NXPH4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NXPH4

    Additional mRNA sequence: 

    AF043469.1 AK094231.1 AK290949.1 AY358614.1 BC036679.1 BC053581.1 

    4 DOTS entries:

    DT.210103  DT.100812180  DT.100812176  DT.100021255 

    24/1296 AceView cDNA sequences (see all 1296):

    BI759953 AA356005 BM786296 BM787444 AU124938 BP872320 CN480736 BE900387 
    BM479665 BQ948999 BM787142 AL557257 BQ440768 CA428887 BI254909 BQ066812 
    AW410517 AU132298 BU170043 BM008051 CD514355 BM794947 BG056020 BU680914 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NXPH4    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b
    SP1:        -                     
    SP2:        -     -               
    SP3:              -               


    ECgene alternative splicing isoforms for NXPH4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NXPH4 expression in normal human tissues (normalized intensities)      NXPH4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGCCCACTC
    NXPH4 Expression
    About this image


    NXPH4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
             brain/midbrain/lateral wall   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
             brain/midbrain/lateral wall   
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Neural Crest (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor

    See NXPH4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NXPH4

    SOURCE GeneReport for Unigene cluster: Hs.745023

    UniProtKB/Swiss-Prot: NXPH4_HUMAN, O95158
    Tissue specificity: Expressed in brain, spleen, and testis

        SABiosciences Custom PCR Arrays for NXPH4
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NXPH4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXPH4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NXPH4 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nxph41 , 5 neurexophilin 41, 5 88.05(n)1
    90.46(a)1
      10 (74.51 cM)5
    1040801  NM_183297.21  NP_899120.21 
     1275254735 
    chicken
    (Gallus gallus)
    Aves LOC1008587431 neurexophilin-4-like 70.65(n)
    73.13(a)
      100858743  XM_003643560.1  XP_003643608.1 
    lizard
    (Anolis carolinensis)
    Reptilia NXPH46
    Uncharacterized protein
    59(a)
    1 ↔ 1
    GL343212.1(1832672-1833421)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003295631 neurexophilin-1-like 69.23(n)
    68.72(a)
      100329563  XM_002667224.2  XP_002667270.2 


    ENSEMBL Gene Tree for NXPH4 (if available)
    TreeFam Gene Tree for NXPH4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NXPH4 gene
    NXPH12  NXPH32  NXPH22  
    3 SIMAP similar genes for NXPH4 using alignment to 3 protein entries:     NXPH4_HUMAN (see all proteins):
    NXPH2    NXPH1    Nbla00697

    NXPH4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/234 SNPs in NXPH4 are shown (see all 234)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1874050881,2
    --57608606(+) CACTCC/TGCCTG 1 -- us2k10--------
    rs1922501991,2
    --57608711(+) GGGAAA/GAACCA 1 -- us2k10--------
    rs1473430671,2
    --57608754(+) GATACC/TGAATG 1 -- us2k10--------
    rs1855012221,2
    --57608820(+) CAGGGC/TGAGTA 1 -- us2k10--------
    rs1904383681,2
    --57608863(+) GCGAGC/TGCGCA 1 -- us2k10--------
    rs1394916921,2
    --57608864(+) CGAGCA/GCGCAC 1 -- us2k10--------
    rs1932962281,2
    --57608944(+) GGGTTC/TGGCCC 1 -- us2k10--------
    rs1429636191,2
    --57608985(+) CTGTCA/CTGGAC 1 -- us2k10--------
    rs800225591,2
    F--57609047(+) CGTGCC/ATGGAA 1 -- us2k11Minor allele frequency- A:0.50NA 4
    rs1511290201,2
    --57609172(+) CTTCTA/GCCTGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NXPH4 (57610578 - 57620232 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NXPH4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv899116CNV Loss21882294
    dgv96n21CNV Loss19592680
    nsv519293CNV Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NXPH4
    DNA2.0 Custom Variant and Variant Library Synthesis for NXPH4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604637    OMIM disorders: --

    2 diseases for NXPH4:    About MalaCards
    otitis externa    cystic kidney

    1 disease from the University of Copenhagen DISEASES database for NXPH4:
    Otitis externa

    NXPH4 for disorders           About GeneDecksing


    Export disorders for NXPH4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NXPH4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NXPH4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Neurexophilins form a conserved family of neuropeptide-like glycoproteins. (PubMed id 9570794)1, 2, 3 Missler M. and Suedhof T.C. (1998)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11247 HGNC: 8078 AceView: SHMT2andNXPH4 Ensembl:ENSG00000182379 euGenes: HUgn11247
    ECgene: NXPH4 H-InvDB: NXPH4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NXPH4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NXPH4 gene:
    Search GeneIP for patents involving NXPH4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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