Aliases for NXNL1 Gene
External Ids for NXNL1 Gene
Previous HGNC Symbols for NXNL1 Gene
Previous GeneCards Identifiers for NXNL1 Gene
Retinitis pigmentosa (RP) is a disease that leads to blindness by degeneration of cone photoreceptors. Rods produce factors required for cone viability. The protein encoded by this gene is one of those factors and is similar to a truncated form of thioredoxin. This gene has been proposed to have therapeutic value against RP. [provided by RefSeq, Dec 2015]
GeneCards Summary for NXNL1 Gene
NXNL1 (Nucleoredoxin-Like 1) is a Protein Coding gene. Diseases associated with NXNL1 include Retinitis Pigmentosa Autosomal Recessive and Retinitis Pigmentosa. An important paralog of this gene is NXNL2.
UniProtKB/Swiss-Prot for NXNL1 Gene
May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods.