Aliases for NXN Gene
External Ids for NXN Gene
- HGNC: 18008
- Entrez Gene: 64359
- Ensembl: ENSG00000167693
- OMIM: 612895
- UniProtKB: Q6DKJ4
Previous GeneCards Identifiers for NXN Gene
- GC17M000778
- GC17M000906
- GC17M000656
- GC17M000687
- GC17M000649
- GC17M000702
- GC17M000613
Summaries for NXN Gene
-
This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation. [provided by RefSeq, Sep 2015]
GeneCards Summary for NXN Gene
NXN (Nucleoredoxin) is a Protein Coding gene. Diseases associated with NXN include Vulvitis and Vulvar Disease. GO annotations related to this gene include oxidoreductase activity and thioredoxin-disulfide reductase activity. An important paralog of this gene is NXNL1.
UniProtKB/Swiss-Prot for NXN Gene
-
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NXN Gene
Genomics for NXN Gene
Regulatory Elements for NXN Gene
- Transcription factor binding sites by QIAGEN in the NXN gene promoter:
Regulatory Element Products
Genomic Location for NXN Gene
- Chromosome:
- 17
- Start:
- 799,313 bp from pter
- End:
- 979,770 bp from pter
- Size:
- 180,458 bases
- Orientation:
- Minus strand
Genomic View for NXN Gene
- Cytogenetic band:
-
- 17p13.3 by Ensembl
- 17p13.3 by Entrez Gene
- 17p13.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NXN Gene
Proteins for NXN Gene
-
Protein details for NXN Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6DKJ4-NXN_HUMAN
- Recommended name:
- Nucleoredoxin
- Protein Accession:
- Q6DKJ4
- B4DXQ0
- D3DTH2
- Q3SWW6
- Q6P3U6
- Q7L4C6
- Q9H9Q1
Protein attributes for NXN Gene
- Size:
- 435 amino acids
- Molecular mass:
- 48392 Da
- Quaternary structure:
-
- Associates with the phosphatase 2A holoenzyme. Interacts with PPP2CA; the interaction is direct. Interacts with DVL1 (via PDZ domain); the interaction is direct and regulated by oxidative stress (By similarity).
- SequenceCaution:
-
- Sequence=BAB14171.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB55122.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for NXN Gene
Selected DME Specific Peptides for NXN Gene
- Q6DKJ4:
-
- EKHRKLKLWNK
- PLLFFVAGEDDM
- DMPWLALPY
- EGPCLVLFVD
- QYFSEMPWLAVPY
- GLEFPWGPKPF
- VCRNGLL
- RLEIVFVSSD
- DSLRDYTNLPEAAPLLTILDMSARAKYV
- EVIAGPL
- GESEAAKQLIQPIAEKIIA
- VGVYFSAHWCPPCRSLTRVLVESYRK
- GEVITRQGRVEVL
- DEARRSRLNRLYGIQGIP
Post-translational modifications for NXN Gene
Other Protein References for NXN Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for NXN (Nucleoredoxin)
-
Custom Antibody ServicesOriGene Antibodies for NXN
- Novus Biologicals Antibodies for NXN
-
Cloud-Clone Corp. Antibodies for NXN
- Invitrogen Antibodies for NXN
- antibodies-online Antibodies for NXN: See all 38
- GeneTex NXN antibody for NXN
- GeneTex Nes antibody for NXN
-
Santa Cruz Biotechnology (SCBT) Antibodies for NXN
Protein Products
-
OriGene Purified Proteins for NXN
- Search Origene for MassSpec and Protein Over-expression Lysates for NXN
- Origene Custom Protein Services for NXN
-
Cloud-Clone Corp. Proteins for NXN
- antibodies-online Proteins for NXN: See all 12
- Search antibodies-online for peptides
- Search GeneTex for Proteins for NXN
Domains & Families for NXN Gene
Protein Domains for NXN Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NXN Gene
Graphical View of Domain Structure for InterPro Entry
Q6DKJ4- Family:
-
- Belongs to the nucleoredoxin family.
No data available for Gene Families for NXN Gene
Function for NXN Gene
Molecular function for NXN Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Protein dithiol + NAD(P)(+) = protein disulfide + NAD(P)H.
- UniProtKB/Swiss-Prot Function:
- Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Enzyme Numbers (IUBMB) for NXN Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004791 | thioredoxin-disulfide reductase activity | IBA | -- |
| GO:0016491 | oxidoreductase activity | IEA | -- |
| GO:0047134 | protein-disulfide reductase activity | IEA | -- |
Phenotypes for NXN Gene
- MGI mutant phenotypes for NXN:
-
inferred from 5 alleles
- mortality/aging
- cellular phenotype
- behavior/neurological phenotype
- growth/size/body region phenotype
- cardiovascular system phenotype
- digestive/alimentary phenotype
- vision/eye phenotype
- hearing/vestibular/ear phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- embryo phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for NXN:
Animal Models for NXN Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for NXN
- Cyagen custom Knockout/knockin (KOKI) mouse models for NXN
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NXN gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NXN gene
- Search ViGene Biosciences for NXN
CRISPR Products
-
OriGene CRISPR knockouts for NXN
-
Santa Cruz Biotechnology (SCBT) CRISPR for NXN
- GenScript: Design CRISPR guide RNA sequences for NXN
miRNA for NXN Gene
- miRTarBase miRNAs that target NXN
-
- hsa-let-7b-5p (MIRT001611)
- hsa-mir-124-3p (MIRT022572)
- hsa-mir-1-3p (MIRT023721)
- hsa-mir-652-3p (MIRT039562)
- hsa-mir-186-5p (MIRT045235)
- hsa-mir-92a-3p (MIRT049102)
- hsa-mir-30c-2-3p (MIRT482668)
- hsa-mir-7111-5p (MIRT482669)
- hsa-mir-6870-5p (MIRT482670)
- hsa-mir-5698 (MIRT482671)
- hsa-mir-4723-5p (MIRT482672)
- hsa-mir-7106-5p (MIRT482673)
- hsa-mir-6825-5p (MIRT482674)
- hsa-mir-765 (MIRT482675)
- hsa-mir-5703 (MIRT482676)
- hsa-mir-4516 (MIRT482677)
- hsa-mir-4434 (MIRT482678)
- hsa-mir-4533 (MIRT482679)
- hsa-mir-4784 (MIRT482680)
- hsa-mir-3150b-3p (MIRT482681)
- hsa-mir-6770-5p (MIRT482682)
- hsa-mir-6794-5p (MIRT482683)
- hsa-mir-4716-3p (MIRT482684)
- hsa-mir-4478 (MIRT482685)
- hsa-mir-4419b (MIRT482686)
- hsa-mir-4779 (MIRT482687)
- hsa-mir-3929 (MIRT482688)
- hsa-mir-6876-5p (MIRT482689)
- hsa-mir-4476 (MIRT482690)
- hsa-mir-6891-5p (MIRT482691)
- hsa-mir-3173-3p (MIRT482692)
- hsa-mir-296-5p (MIRT492824)
- hsa-mir-4529-5p (MIRT492825)
- hsa-mir-4707-5p (MIRT492826)
- hsa-mir-6840-5p (MIRT492827)
- hsa-mir-4743-5p (MIRT572331)
- hsa-mir-6510-3p (MIRT689452)
- hsa-mir-6888-3p (MIRT689453)
- hsa-mir-1287-3p (MIRT689454)
- hsa-mir-1273a (MIRT689455)
- hsa-mir-4522 (MIRT689456)
- hsa-mir-3120-5p (MIRT689457)
- hsa-mir-1251-5p (MIRT689458)
- hsa-mir-616-5p (MIRT689459)
- hsa-mir-373-5p (MIRT689460)
- hsa-mir-371b-5p (MIRT689461)
- hsa-mir-6784-5p (MIRT689462)
- hsa-mir-3613-3p (MIRT689463)
- hsa-mir-3664-5p (MIRT689464)
- hsa-mir-5684 (MIRT689465)
miRNA Products
- Search ViGene Biosciences for NXN
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for NXN
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-
ViGene Biosciences ready-to-package AAV shRNAs for NXN gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NXN
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NXN
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for NXN
-
ViGene Biosciences adenoviral particle packaged cDNA for NXN gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NXN gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NXN gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NXN Gene
Localization for NXN Gene
Subcellular locations from UniProtKB/Swiss-Prot for NXN Gene
- Cytoplasm, cytosol. Nucleus.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IBA,IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
Pathways & Interactions for NXN Gene
Interacting Proteins for NXN Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0016055 | Wnt signaling pathway | IEA | -- |
| GO:0030154 | cell differentiation | IEA | -- |
| GO:0030178 | negative regulation of Wnt signaling pathway | IEA,ISS | -- |
| GO:0031397 | negative regulation of protein ubiquitination | IEA,ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for NXN Gene
Drugs & Compounds for NXN Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| NAD | Pharma | Full agonist, Agonist | 0 |
Transcripts for NXN Gene
mRNA/cDNA for NXN Gene
- (5) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (162) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for NXN
-
Santa Cruz Biotechnology (SCBT) CRISPR for NXN
- GenScript: Design CRISPR guide RNA sequences for NXN
miRNA Products
- Search ViGene Biosciences for NXN
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for NXN
- Browse OriGene Inhibitory RNA Products For NXN
-
ViGene Biosciences ready-to-package AAV shRNAs for NXN gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NXN
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NXN
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||||||||||
| SP5: |
Expression for NXN Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Blood (Hematopoietic System)
- Mesenchymal Stem Cells
- Umbilical Cord (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for NXN Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NXN Gene
NURSA nuclear receptor signaling pathways regulating expression of NXN Gene:
NXNSOURCE GeneReport for Unigene cluster for NXN Gene:
Hs.527989Evidence on tissue expression from TISSUES for NXN Gene
- Nervous system(4.4)
- Lung(4.3)
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for NXN
-
OriGene qPCR primer pairs and template standards for NXN
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NXN Gene
Orthologs for NXN Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NXN 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | NXN 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | NXN 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Nxn 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Nxn 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NXN 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | NXN 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NXN 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | NXN 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | nxn 34 |
|
||
| Str.10653 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12749 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | nxn 34 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2967 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | T28A11.13 35 |
|
ManyToMany | |
| T20D4.7 35 |
|
ManyToMany | |||
| trx-5 35 |
|
ManyToMany | |||
| C32D5.8 35 |
|
ManyToMany | |||
| Y52E8A.3 35 |
|
ManyToMany | |||
| R05H5.3 35 |
|
ManyToMany | |||
| F29B9.5 35 |
|
ManyToMany | |||
| C35B1.5 35 |
|
ManyToMany | |||
| C30H6.8 35 |
|
ManyToMany | |||
| trx-3 35 |
|
ManyToMany | |||
| T05F1.11 35 |
|
ManyToMany | |||
| F17B5.1 35 |
|
ManyToMany |
- Species where no ortholog for NXN was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for NXN Gene
(1) SIMAP similar genes for NXN Gene using alignment to 3 proteins:
Pseudogenes.org Pseudogenes for NXN Gene
Variants for NXN Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000020315 | -- | 893,823(+) | CAACT(A/C)CCTGG | intron-variant | |
| rs1000049979 | -- | 976,689(+) | CCCTA(A/G)CTTCA | intron-variant | |
| rs1000052554 | -- | 978,689(+) | CACAG(A/C)CACGG | intron-variant | |
| rs1000052743 | -- | 894,747(+) | CGGGC(A/G)GAGAC | intron-variant | |
| rs1000054489 | -- | 920,204(+) | CTACA(A/C)CCCGA | intron-variant |
Relevant External Links for NXN Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NXN Gene
Disorders for NXN Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| vulvitis |
|
|
| vulvar disease |
|
|
| polycystic liver disease |
|
|
Relevant External Links for NXN
No data available for UniProtKB/Swiss-Prot and Genatlas for NXN Gene
Publications for NXN Gene
- Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. (PMID: 19308021) Ollila H.M. … Paunio T. (Mol. Psychiatry 2009) 3 46 64
- Interaction of nucleoredoxin with protein phosphatase 2A. (PMID: 16764867) Lechward K. … Zolnierowicz S. (FEBS Lett. 2006) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. (PMID: 25756610) Papp S.J. … Lamia K.A. (Elife 2015) 3 64
Products for NXN Gene
- R&D Systems Antibodies for NXN (Nucleoredoxin)
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- Custom Antibody ServicesOriGene Antibodies for NXN
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for NXN
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- Browse OriGene Inhibitory RNA Products For NXN
- OriGene qPCR primer pairs and template standards for NXN
- OriGene qPCR primer pairs for NXN
- OriGene CRISPR knockouts for NXN
- OriGene ORF clones in human for NXN
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Browse Sino Biological cDNA Clones
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for NXN
- Novus Biologicals proteins and lysates for NXN
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for NXN
- Cloud-Clone Corp. Proteins for NXN
- Cloud-Clone Corp Assay Kits for NXN
- Taconic Biosciences Mouse Models for NXN
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for NXN: See all 38
- antibodies-online Kits for NXN: See all 6
- antibodies-online Proteins for NXN: See all 12
- Search antibodies-online for peptides
- GeneTex Nes antibody for NXN
- GeneTex NXN antibody for NXN
- Search GeneTex for Proteins for NXN
- ViGene Biosciences adenoviral particle packaged cDNA for NXN gene
- ViGene Biosciences lentiviral particle packaged cDNA for NXN gene
- ViGene Biosciences ready-to-package AAV shRNAs for NXN gene
- Search ViGene Biosciences for NXN
- Santa Cruz Biotechnology (SCBT) Antibodies for NXN
- Search Santa Cruz Biotechnology (SCBT) for NXN siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NXN
- Horizon Cell Lines for NXN
- Cyagen custom Knockout/knockin (KOKI) mouse models for NXN
- VectorBuilder custom plasmid, inducible vectors for NXN
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NXN
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for NXN Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
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