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NXF5 Gene

protein-coding   GIFtS: 50
GCID: GC0XM101087

Nuclear RNA Export Factor 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear RNA Export Factor 51 2
TAPL-12 3
TAP-Like Protein 12 3
TAPL13

External Ids:    HGNC: 80751   Entrez Gene: 559982   Ensembl: ENSG000001269527   OMIM: 3003195   UniProtKB: Q9H1B43   

Export aliases for NXF5 gene to outside databases

Previous GC identifers: GC0XM096378 GC0XM098028 GC0XM099122 GC0XM099858 GC0XM100893 GC0XM100973 GC0XM090894


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NXF5 Gene:
This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is
implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in
other family members that are required for export activity, and may be an evolving pseudogene. Alternatively
spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and
may not express proteins in vivo. (provided by RefSeq, Jul 2009)

GeneCards Summary for NXF5 Gene:
NXF5 (nuclear RNA export factor 5) is a protein-coding gene. Diseases associated with NXF5 include pelizaeus-merzbacher disease, and premature ovarian failure. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is NXF1.

UniProtKB/Swiss-Prot: NXF5_HUMAN, Q9H1B4
Function: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in
polarized cytoplasmic transport and localization of mRNA in neurons




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NXF5
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNXF5 promoter sequence
   Search Chromatin IP Primers for NXF5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NXF5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22

NXF5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NXF5 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM101087:  view genomic region     (about GC identifiers)

Start:
101,087,085 bp from pter      End:
101,112,549 bp from pter
Size:
25,465 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NXF5_HUMAN, Q9H1B4 (See protein sequence)
Recommended Name: Nuclear RNA export factor 5  
Size: 397 amino acids; 45628 Da
Subunit: Interacts with NXT1 and NXT2
Secondary accessions: A2RRM0 B1AV82 B1AV83 B1AV84 B1AV85 Q9H1B0 Q9H1B1 Q9H1B2 Q9H1B3
Alternative splicing: 6 isoforms:  Q9H1B4-1   Q9H1B4-2   Q9H1B4-3   Q9H1B4-4   Q9H1B4-5   Q9H1B4-6   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for NXF5: NX_Q9H1B4

Explore proteomics data for NXF5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NXF5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116564.2  
    ENSEMBL proteins: 
     ENSP00000263032   ENSP00000361889   ENSP00000422976   ENSP00000354539   ENSP00000331535  
     ENSP00000426978   ENSP00000442401   ENSP00000355286  

    NXF5 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for NXF5

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    Cloud-Clone Corp. CLIAs for NXF5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR015245 Tap_RNA-bd
     IPR001611 Leu-rich_rpt
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q9H1B4

    ProtoNet protein and cluster: Q9H1B4

    1 Blocks protein domain: IPB002075 Nuclear transport factor 2 (NTF2)

    UniProtKB/Swiss-Prot: NXF5_HUMAN, Q9H1B4
    Domain: The NTF2 domain heterodimerizes with NXT1 and NXT2 (By similarity)
    Domain: The RNA-binding domain is a non-canonical RNP-type domain
    Similarity: Belongs to the NXF family
    Similarity: Contains 4 LRR (leucine-rich) repeats
    Similarity: Contains 1 NTF2 domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    NXF5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NXF5_HUMAN, Q9H1B4
    Function: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in
    polarized cytoplasmic transport and localization of mRNA in neurons

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003723RNA binding IDA11566096
    GO:0005515protein binding IPI11566096
         
    NXF5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NXF5:
     Cell cycle / mitosis defect 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NXF5
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NXF5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NXF5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NXF5

    miRNA
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    Block miRNA regulation of human, mouse, rat NXF5 using miScript Target Protectors
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    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: NXF5 (NM_032946)
    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXF5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NXF5_HUMAN, Q9H1B4: Cytoplasm. Nucleus. Note=Mainly localized in the cytoplasm of cells and more particularly in
    the cell body and neurites of hippocampal neurons. Although nuclear localization is also observed. Not detected
    at nuclear rim
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    cytosol3
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA11566096
    GO:0005737cytoplasm IDA11566096
    GO:0015629actin cytoskeleton ----

    NXF5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NXF5 About    
    See pathways by source

    SuperPathContained pathways About
    1Influenza A
    Influenza A0.34
    Herpes simplex infection0.33
    2RNA transport
    RNA transport
    3Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes
    4mRNA surveillance pathway
    mRNA surveillance pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5 Kegg Pathways  (Kegg details for NXF5):
        Ribosome biogenesis in eukaryotes
    RNA transport
    mRNA surveillance pathway
    Influenza A
    Herpes simplex infection


    NXF5 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NXF5
    Interactions:

        Search GeneGlobe Interaction Network for NXF5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NXF5 (ENSP000002630324) via UniProtKB, MINT, STRING, and/or I2D (see all 79)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALYREFENSP000003318174STRING: ENSP00000331817
    EIF4A3ENSP000002693494STRING: ENSP00000269349
    NUP98ENSP000003160324STRING: ENSP00000316032
    NUPL2ENSP000002587424STRING: ENSP00000258742
    NXT1ENSP000002549984STRING: ENSP00000254998
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006406mRNA export from nucleus IDA11566096
    GO:0007275multicellular organismal development IEP11566096
    GO:0050658RNA transport IDA11566096

    NXF5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NXF5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NXF5 gene (5 alternative transcripts): 
    NM_032946.2  NM_033152.1  NM_033153.1  NM_033154.1  NM_033155.1  

    Unigene Cluster for NXF5:

    Nuclear RNA export factor 5
    Hs.307077
    Unigene Representative Sequence: AJ277654
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263032(uc004eih.1) ENST00000372803(uc004eij.1) ENST00000493509(uc004eii.1)
    ENST00000361330(uc004eik.1) ENST00000332614(uc004eil.1) ENST00000473265
    ENST00000537026(uc011mrk.1) ENST00000361708
    miRNA
    Products:
         
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    Search for qRT-PCR Assays for microRNAs that regulate NXF5
    SwitchGear 3'UTR luciferase reporter plasmidNXF5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NXF5
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    GenScript: all cDNA clones in your preferred vector: NXF5 (NM_032946)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NXF5
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat NXF5
      QuantiFast Probe-based Assays in human, mouse, rat NXF5

    Additional mRNA sequence: 

    AJ277654.1 AJ277655.1 AJ277656.1 AJ277657.1 AJ277658.1 BC131708.1 NR_028089.1 

    1 DOTS entry:

    DT.91758145 

    10 AceView cDNA sequences:

    AJ277657 NM_033152 NM_032946 NM_033155 AJ277655 AJ277658 NM_033154 NM_033153 
    AJ277656 AJ277654 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NXF5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NXF5 Expression
    About this image


    NXF5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    NXF5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NXF5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.307077
        Custom PCR Arrays for NXF5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXF5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NXF5 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    fruit fly
    (Drosophila melanogaster)
    Insecta nxf26
    sbr6
    (see all 3)
    small bristles
    (see all 3)
    9(a)
    15(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    3L(16569959-16573406)
    X(10726785-10741125)
    worm
    (Caenorhabditis elegans)
    Secernentea nxf-26
    nxf-16
    Protein NXF-1, isoform a
    16(a)
    14(a)
    many ↔ many
    many ↔ many
    V(14416115-14417829) WBGene00003835
    V(14412405-14415792) WBGene00003834
            Species with no ortholog for NXF5

    ENSEMBL Gene Tree for NXF5 (if available)
    TreeFam Gene Tree for NXF5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NXF5 gene
    NXF12  NXF32  NXF2B2  NXF22  
    4 SIMAP similar genes for NXF5 using alignment to 2 protein entries:     NXF5_HUMAN (see all proteins):
    NXF2B    NXF2    NXF1    NXF3

    NXF5 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NXF5
    PGOHUM00000241917


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NXF5 (see all 500)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1904867601,2
    --101054239(+) AATGTC/GAGATT 2 -- ds50010--------
    rs1817991521,2
    --101054290(+) TGAACC/TCCTTC 2 -- ds50010--------
    rs1474580011,2
    C--101054373(+) CCCACC/TGCAGG 2 -- ds50010--------
    rs59450791,2
    C,F,A,H--101054445(+) TGGAAG/CCCCCT 2 -- ds50015Minor allele frequency- C:0.02NS EA NA 410
    rs1405803361,2
    --101054493(+) AGGTCA/GAGCAT 2 -- ds50010--------
    rs1896031401,2
    --101054545(+) GGGCGC/TGTGTC 2 -- ds50010--------
    rs1445316941,2
    --101054599(+) GCCAGA/TTCATT 2 -- ds50010--------
    rs66163051,2
    C,F,A,H--101054674(+) CTCATG/CGTTGG 2 -- ds50018Minor allele frequency- C:0.10NS EA NA WA 426
    rs1813221251,2
    --101054681(+) TTGGGG/TCAGGG 2 -- ds50010--------
    rs1854552681,2
    --101054705(+) GGGCAC/TACAAC 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for NXF5 (101087085 - 101112549 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NXF5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv987918CNV Deletion20482838
    esv2740360CNV Deletion23290073
    esv2740359CNV Deletion23290073
    nsv7015CNV Loss18451855

    Human Gene Mutation Database (HGMD): NXF5
    Locus Specific Mutation Databases (LSDB): NXF5

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NXF5
    DNA2.0 Custom Variant and Variant Library Synthesis for NXF5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300319    OMIM disorders: --

    UniProtKB/Swiss-Prot: NXF5_HUMAN, Q9H1B4
  • Note=A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of
    mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5

  • 15 diseases for NXF5:    
    About MalaCards
    pelizaeus-merzbacher disease    premature ovarian failure    intellectual disability    short stature
    influenza    tonsillitis    mental retardation    herpes simplex
    multiple myeloma    myeloma    cerebritis    neuronitis
    thyroiditis    endotheliitis    prostatitis


    NXF5 for disorders           About GeneDecksing


    Export disorders for NXF5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NXF5 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with NXF5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. (PubMed id 11566096)1, 2, 3, 9 Jun L.... Froyen G. (Curr. Biol. 2001)
    2. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
    3. Inv(X)(p21.1;q22.1) in a man with mental retardation, short stature, general muscle wasting, and facial dysmorphism: clinical study and mutation analysis of the NXF5 gene. (PubMed id 12784308)1, 9 Frints S.G....Froyen G. (Am. J. Med. Genet. A 2003)
    4. Unique X-linked familial FSGS with co-segregating heart block disorder is associated with a mutation in the NXF5 gene. (PubMed id 23686279)1 Esposito T....Griffiths L.R. (Hum. Mol. Genet. 2013)
    5. A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. (PubMed id 19377476)1 Tarpey P.S.... Stratton M.R. (Nat. Genet. 2009)
    6. Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins. (PubMed id 17978099)1 Matzat L.H....LAcvesque L. (Mol. Biol. Cell 2008)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55998 HGNC: 8075 AceView: NXF5 Ensembl:ENSG00000126952 euGenes: HUgn55998
    ECgene: NXF5 Kegg: 55998 H-InvDB: NXF5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NXF5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NXF5 gene:
    Search GeneIP for patents involving NXF5

    GeneCards and IP:
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