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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NXF3 Gene

protein-coding   GIFtS: 55
GCID: GC0XM102330

Nuclear RNA Export Factor 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nuclear RNA Export Factor 31 2
TAPL-32 3
TAP-Like Protein 32 3
TAPL33

External Ids:    HGNC: 80731   Entrez Gene: 560002   Ensembl: ENSG000001472067   OMIM: 3003165   UniProtKB: Q9H4D53   

Export aliases for NXF3 gene to outside databases

Previous GC identifers: GC0XM097632 GC0XM099239 GC0XM100363 GC0XM101102 GC0XM102136 GC0XM102219 GC0XM091994


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NXF3 Gene:
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are
a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2
(NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a
ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are
required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The
encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind
RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
(provided by RefSeq, Jul 2008)

GeneCards Summary for NXF3 Gene: 
NXF3 (nuclear RNA export factor 3) is a protein-coding gene. Diseases associated with NXF3 include pelizaeus-merzbacher disease, and influenza, and among its related super-pathways are Influenza A. GO annotations related to this gene include mRNA binding and nucleotide binding. An important paralog of this gene is NXF1.

UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
Function: May function as a tissue-specific nuclear mRNA export factor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NXF3 gene promoter:
         COUP-TF1   TBP   AML1a   COUP   STAT5A   HNF-4alpha2   HNF-4alpha1   AREB6   E2F   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNXF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NXF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NXF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22

NXF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NXF3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM102330:  view genomic region     (about GC identifiers)

Start:
102,330,738 bp from pter      End:
102,348,157 bp from pter
Size:
17,420 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5 (See protein sequence)
Recommended Name: Nuclear RNA export factor 3  
Size: 531 amino acids; 60102 Da
Subunit: Interacts with NXT1, NXT2, E1B-AP5 and CRM1 nuclear export factor
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm
Sequence caution: Sequence=CAC20434.1; Type=Frameshift; Positions=463;
Secondary accessions: Q5H9I1 Q9H1A9

Explore the universe of human proteins at neXtProt for NXF3: NX_Q9H4D5

Explore proteomics data for NXF3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H4D5

  • NXF3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NXF3 Protein Expression
    REFSEQ proteins: NP_071335.1  
    ENSEMBL proteins: 
     ENSP00000378504   ENSP00000404017   ENSP00000401026   ENSP00000404347  

    Human Recombinant Protein Products for NXF3: 
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    OriGene Protein Over-expression Lysate for NXF3
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    Novus Biologicals NXF3 Proteins
    Novus Biologicals NXF3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NXF3 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA11545741
    GO:0005737cytoplasm IDA--
    GO:0042272nuclear RNA export factor complex IDA11545741

    NXF3 for ontologies           About GeneDecksing



    NXF3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR002075 NTF2
     IPR015245 Tap_RNA-bd
     IPR012677 Nucleotide-bd_a/b_plait
     IPR018222 Nuclear_transport_factor_2_euk

    Graphical View of Domain Structure for InterPro Entry Q9H4D5

    ProtoNet protein and cluster: Q9H4D5

    1 Blocks protein domain: IPB002075 Nuclear transport factor 2 (NTF2)

    UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
    Domain: Lacks C-terminal domain that mediates direct interactions with nucleoporins
    Domain: Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear
    pore targeting domain
    Domain: The RNA-binding domain is a non-canonical RNP-type domain
    Similarity: Belongs to the NXF family
    Similarity: Contains 1 NTF2 domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    NXF3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NXF3_HUMAN, Q9H4D5
    Function: May function as a tissue-specific nuclear mRNA export factor

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003723RNA binding ----
    GO:0003729mRNA binding IEA--
    GO:0005515protein binding IPI11545741
         
    NXF3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NXF3:
     Decreased influenza A/WSN/33 r 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Nxf3):
     endocrine/exocrine gland  mortality/aging  reproductive system 

    NXF3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nxf3tm1.2Jw for NXF3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NXF3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NXF3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NXF3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NXF3 

    miRNA
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXF3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NXF3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Influenza A
    Influenza A0.34
    Herpes simplex infection0.33
    2mRNA surveillance pathway
    mRNA surveillance pathway
    3Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes
    4RNA transport
    RNA transport

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5         Kegg Pathways  (Kegg details for NXF3):
        Ribosome biogenesis in eukaryotes
    RNA transport
    mRNA surveillance pathway
    Influenza A
    Herpes simplex infection


    NXF3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NXF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for NXF3 (Q9H4D51, 3 ENSP000003785044) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NXT1Q9UKK61, 3, ENSP000002549984EBI-750038,EBI-301889 I2D: score=4 STRING: ENSP00000254998
    NUP214P356583, ENSP000003524004I2D: score=1 STRING: ENSP00000352400
    NXT2Q9NPJ83, ENSP000002180044I2D: score=5 STRING: ENSP00000218004
    HNRNPUL1Q9BUJ23, ENSP000003758634I2D: score=1 STRING: ENSP00000375863
    XPO1O149803I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006406mRNA export from nucleus IDA11545741
    GO:0006810transport ----
    GO:0016973poly(A)+ mRNA export from nucleus IEA--

    NXF3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NXF3

    Search CenterWatch for drugs/clinical trials and news about NXF3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NXF3 gene: 
    NM_022052.1  

    Unigene Cluster for NXF3:

    Nuclear RNA export factor 3
    Hs.60386  [show with all ESTs]
    Unigene Representative Sequence: AK057086
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395065(uc010noi.1 uc004eju.3) ENST00000497850 ENST00000468528
    ENST00000470724 ENST00000427570 ENST00000494300 ENST00000497215 ENST00000460791
    ENST00000425644 ENST00000425463(uc011mrw.1 uc011mrx.1)
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNXF3 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NXF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NXF3

    Additional mRNA sequence: 

    AF346619.1 AJ277527.1 AJ277660.1 AK057086.1 AK294826.1 AK302447.1 AK302586.1 BC031616.1 

    7 DOTS entries:

    DT.40308041  DT.309032  DT.91856969  DT.121305693  DT.70105474  DT.99961549  DT.92350413 

    24/30 AceView cDNA sequences (see all 30):

    AA774546 NM_022052 AJ277527 AA343662 AF346619 AA010599 BC031616 BV167188 
    BI831659 BP369864 CD243958 BU171243 BX281560 BM743136 AA010371 BM755614 
    BM743466 BM744580 AA776821 BF376145 BF376130 BF093616 BF172751 AA010370 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NXF3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                                                    -                                                                     
    SP2:                                                                                                                                          
    SP3:              -                                                                                                                           


    ECgene alternative splicing isoforms for NXF3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NXF3 expression in normal human tissues (normalized intensities)      NXF3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCAAGATG
    NXF3 Expression
    About this image


    NXF3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             XY Germ Cells Testis Cord
     
     Ovary (Reproductive System)
             Granulosa Cells Primary Follicle
     
     Gonad
             XY Germ Cells Testis Cord
     
     Stomach (Gastrointestinal Tract)

    See NXF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NXF3

    SOURCE GeneReport for Unigene cluster: Hs.60386

    UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
    Tissue specificity: Expressed at high level in testis and at low level in a small number of tissues

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXF3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NXF3 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nxf31 , 5 nuclear RNA export factor 31, 5 69.51(n)1
    53.96(a)1
      X (57.38 cM)5
    2456101  NM_001024141.41  NP_001019312.11 
     1360720995 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    36(a)
    possible ortholog
    GL343739.1(136184-168794)
    zebrafish
    (Danio rerio)
    Actinopterygii nxf16
    zgc:1536816
    (see all 4)
    zgc:153681
    (see all 4)
    31(a)
    30(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    21(26058501-26071321)
    14(8897699-8935452)
    fruit fly
    (Drosophila melanogaster)
    Insecta sbr6
    Nxf36
    (see all 3)
    Nuclear export factor 3
    (see all 3)
    17(a)
    14(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    X(10726785-10741125)
    3L(13958303-13965106)
    worm
    (Caenorhabditis elegans)
    Secernentea nxf-26
    nxf-16
    Nuclear RNA export factor 1
    20(a)
    15(a)
    many ↔ many
    many ↔ many
    V(14416115-14417829)
    V(14412405-14415792)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MEX676
    Poly(A)RNA binding protein involved in nuclear mRN...
    15(a)
    1 → many
    XVI(229039-230838)


    ENSEMBL Gene Tree for NXF3 (if available)
    TreeFam Gene Tree for NXF3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NXF3 gene
    NXF12  NXF2B2  NXF22  NXF52  
    5 SIMAP similar genes for NXF3 using alignment to 5 protein entries:     NXF3_HUMAN (see all proteins):
    DKFZp667O0311    NXF2B    NXF2    NXF1    NXF5

    NXF3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NXF3
    PGOHUM00000259360


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/355 SNPs in NXF3 are shown (see all 355)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1907387621,2
    --92013761(+) TTGATC/TAAAAT 1 -- us2k10--------
    rs1865232811,2
    --102299681(+) CCACCA/GTGCCC 1 -- ds50010--------
    rs1913783161,2
    C--102299709(+) ATAACG/TATTTG 1 -- ds50010--------
    rs1480828411,2
    C--102299836(+) ATGCTA/GTTTTT 1 -- ds50010--------
    rs1418227791,2
    --102300062(+) TCTAGC/GATTTC 1 -- ds50010--------
    rs735239931,2
    C,F--102300092(+) TTTGAC/ATATCC 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs735239941,2
    C,F--102300469(+) TGGCCG/AAGAGG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs37472981,2
    C,F,H--102300513(+) CGGAAA/GCCCAA 1 -- int19Minor allele frequency- G:0.89NA NS EA 636
    rs1810058711,2
    C--102300577(+) TCACCC/TTGGGC 1 -- ut310--------
    rs1849838131,2
    --102300823(+) TGTGAA/CAGGAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for NXF3 (102330738 - 102348157 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NXF3: --

    Human Gene Mutation Database (HGMD): NXF3

    Locus Specific Mutation Databases (LSDB): NXF3
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NXF3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300316    OMIM disorders: --

    5 diseases for NXF3:    About MalaCards
    pelizaeus-merzbacher disease    influenza    kaposi's sarcoma    mental retardation
    sarcoma

    1 disease from the University of Copenhagen DISEASES database for NXF3:
    Pelizaeus-Merzbacher disease

    NXF3 for disorders           About GeneDecksing


    Export disorders for NXF3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NXF3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with NXF3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. (PubMed id 11073998)1, 2, 3, 9 Herold A.... Izaurralde E. (2000)
    2. Two closely related human nuclear export factors utilize entirely distinct export pathways. (PubMed id 11545741)1, 2, 9 Yang J.... Cullen B.R. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. (PubMed id 11566096)1, 2 Jun L.... Froyen G. (2001)
    5. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)1 Shamay M....Hayward S.D. (2012)
    6. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    7. Formation of a Tap/NXF1 Homotypic Complex Is Mediated through the Amino-Terminal Domain of Tap and Enhances Interaction with Nucleoporins. (PubMed id 17978099)1 Matzat L.H....Levesque L. (2008)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56000 HGNC: 8073 AceView: NXF3 Ensembl:ENSG00000147206 euGenes: HUgn56000
    ECgene: NXF3 Kegg: 56000 H-InvDB: NXF3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NXF3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NXF3 gene:
    Search GeneIP for patents involving NXF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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