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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NXF3 Gene

protein-coding   GIFtS: 55
GCID: GC0XM102330

nuclear RNA export factor 3
 Explore 2 diseases affiliated with
NXF3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NXF3    

Aliases
for NXF3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nuclear RNA Export Factor 31 2
TAPL-32 3
TAP-Like Protein 32 3
TAPL33

External Ids:    HGNC: 80731   Entrez Gene: 560002   Ensembl: ENSG000001472067   OMIM: 3003165   UniProtKB: Q9H4D53   

Export aliases for NXF3 gene to outside databases

Previous GC identifers: GC0XM097632 GC0XM099239 GC0XM100363 GC0XM101102 GC0XM102136 GC0XM102219 GC0XM091994


Summaries
for NXF3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NXF3:
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a
noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2
(NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a
ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required
for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of
this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the
nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
Function: May function as a tissue-specific nuclear mRNA export factor




Genomic Views
for NXF3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NXF3 gene promoter:
         COUP-TF1   TBP   AML1a   COUP   STAT5A   HNF-4alpha2   HNF-4alpha1   AREB6   E2F   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NXF3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NXF3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NXF3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22

NXF3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NXF3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM102330:  view genomic region     (about GC identifiers)

Start:
 102,330,738 bp from pter      End:
 102,348,157 bp from pter
Size:
 17,420 bases      Orientation:
 minus strand

Proteins
for NXF3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5 (See protein sequence)
Recommended Name: Nuclear RNA export factor 3  
Size: 531 amino acids; 60102 Da
Subunit: Interacts with NXT1, NXT2, E1B-AP5 and CRM1 nuclear export factor
Subcellular location: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm
Sequence caution: Sequence=CAC20434.1; Type=Frameshift; Positions=463;
Secondary accessions: Q5H9I1 Q9H1A9

Explore the universe of human proteins at neXtProt for NXF3: NX_Q9H4D5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H4D5

    • NXF3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_071335.1  
    ENSEMBL proteins: 
     ENSP00000378504   ENSP00000404017   ENSP00000401026   ENSP00000404347  

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    Novus Biologicals NXF3 Proteins
    Novus Biologicals NXF3 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NXF3

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA11545741
    GO:0005737cytoplasm IDA--
    GO:0042272nuclear RNA export factor complex IDA11545741


    NXF3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for NXF3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NXF3 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR002075 NTF2
     IPR015245 Tap_RNA-bd
     IPR012677 Nucleotide-bd_a/b_plait
     IPR018222 Nuclear_transport_factor_2_euk

    Graphical View of Domain Structure for InterPro Entry Q9H4D5

    ProtoNet protein and cluster: Q9H4D5

    1 Blocks protein family: IPB002075 Nuclear transport factor 2 (NTF2)

    UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
    Domain: Lacks C-terminal domain that mediates direct interactions with nucleoporins
    Domain: Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear pore
    targeting domain
    Domain: The RNA-binding domain is a non-canonical RNP-type domain
    Similarity: Belongs to the NXF family
    Similarity: Contains 1 NTF2 domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    Function
    for NXF3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
    Function: May function as a tissue-specific nuclear mRNA export factor

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003729mRNA binding IEA--
    GO:0005515protein binding IPI19060904


    NXF3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NXF3:
     Decreased influenza A/WSN/33 r 

    Animal Models:
         Mouse knock-out Nxf3tm1.2Jw for NXF3
         2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Nxf3):
     endocrine/exocrine gland  reproductive system 

    NXF3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NXF3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1mRNA surveillance pathway
    		mRNA surveillance pathway1.00
    2Ribosome biogenesis in eukaryotes
    		Ribosome biogenesis in eukaryotes1.00
    3RNA transport
    		RNA transport1.00
    4Measles
    		Influenza A0.35

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    4         Kegg Pathways  (Kegg details for NXF3):
        Ribosome biogenesis in eukaryotes
    RNA transport
    mRNA surveillance pathway
    Influenza A


    NXF3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NXF3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/17 Interacting proteins for NXF3 (Q9H4D51, 3 ENSP000003785044) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NXT1Q9UKK61, 3, ENSP000002549984EBI-750038,EBI-301889 I2D: score=4 STRING: ENSP00000254998
    NUP214P356583, ENSP000003524004I2D: score=1 STRING: ENSP00000352400
    NXT2Q9NPJ83, ENSP000002180044I2D: score=5 STRING: ENSP00000218004
    HNRNPUL1Q9BUJ23, ENSP000003758634I2D: score=1 STRING: ENSP00000375863
    XPO1O149803I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006406mRNA export from nucleus IDA11545741
    GO:0006810transport ----
    GO:0016973poly(A)+ mRNA export from nucleus IEA--


    NXF3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NXF3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NXF3
    Search CenterWatch for drugs/clinical trials and news about NXF3 

    Transcripts
    for NXF3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NXF3 gene: 
    NM_022052.1  

    Unigene Cluster for NXF3:

    Nuclear RNA export factor 3
    Hs.60386  [show with all ESTs]
    Unigene Representative Sequence: AK057086
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395065(uc010noi.1 uc004eju.3) ENST00000497850 ENST00000468528
    ENST00000470724 ENST00000427570 ENST00000494300 ENST00000497215 ENST00000460791
    ENST00000425644 ENST00000425463(uc011mrw.1 uc011mrx.1)

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: NXF3
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    Clone
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    GenScript: all cDNA clones in your preferred vector: NXF3 (NM_022052)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NXF3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NXF3

    Additional cDNA sequence: 

    AF346619.1 AJ277527.1 AJ277660.1 AK057086.1 AK294826.1 AK302447.1 AK302586.1 BC031616.1 

    7 DOTS entries:

    DT.40308041  DT.309032  DT.91856969  DT.121305693  DT.70105474  DT.99961549  DT.92350413 

    24/30 AceView cDNA sequences (see all 30):

    AA774546 AF346619 AJ277527 NM_022052 AA343662 AA010599 BC031616 BM755614 
    BV167188 BP369864 BU171243 BM744580 CD243958 BX281560 BI831659 BM743136 
    AA776821 AA010371 BM743466 AA010370 BF376145 BF172751 BM755180 BF093616 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for NXF3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20
    SP1:                                                                    -                                                                     
    SP2:                                                                                                                                          
    SP3:              -                                                                                                                           


    ECgene alternative splicing isoforms for NXF3

    Expression
    for NXF3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NXF3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCAAGATG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NXF3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FollicleGranulosa CellsOvary
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NXF3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NXF3

    SOURCE GeneReport for Unigene cluster: Hs.60386

    UniProtKB/Swiss-Prot: NXF3_HUMAN, Q9H4D5
    Tissue specificity: Expressed at high level in testis and at low level in a small number of tissues

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    In Situ
    Assay Products:     
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    Orthologs
    for NXF3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NXF3 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nxf31 , 5 nuclear RNA export factor 31, 5 69.51(n)1
    53.96(a)1    		   X (57.38 cM)5
    2456101  NM_001024141.41  NP_001019312.11 
     1360720995 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 37(a)
    		 1 → many
    		 GL343739.1(139249-168794)
    zebrafish
    (Danio rerio)    		 Actinopterygii nxf16
    zgc:1536816
    (see all 4)    		 zgc:153681
    (see all 4)    		 31(a)
    29(a)
    (see all 4)    		 many ↔ many
    many ↔ many
    (see all 4)    		 21(26058501-26071321)
    14(8793105-8826876)
    fruit fly
    (Drosophila melanogaster)    		 Insecta sbr6
    Nxf36
    (see all 3)    		 Nuclear export factor 3
    (see all 3)    		 17(a)
    14(a)
    (see all 3)    		 many → 1
    possible ortholog
    (see all 3)    		 X(10726785-10741125)
    3L(13958303-13965106)
    worm
    (Caenorhabditis elegans)    		 Secernentea nxf-26
    nxf-16
    		 Nuclear RNA export factor 1
    		 20(a)
    16(a)
    		 possible ortholog
    possible ortholog
    		 V(14416100-14417814)
    V(14412390-14415777)


    ENSEMBL Gene Tree for NXF3 (if available)
    TreeFam Gene Tree for NXF3 (if available) 

    Paralogs
    for NXF3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NXF3 gene
    NXF12  NXF2B2  NXF22  NXF52  
    5 SIMAP similar genes for NXF3 using alignment to 5 protein entries:     NXF3_HUMAN (see all proteins):
    DKFZp667O0311    NXF2    NXF2B    NXF1    NXF5

    NXF3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NXF3
    PGOHUM00000259360


    Genomic Variants
    for NXF3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/231 NCBI SNPs in NXF3 are shown (see all 231)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1865232811,2
    		--102330274(+) CCACCA/GTGCCC 1 -- ds50010--------
    rs1913783161,2
    		--102330302(+) ATAACG/TATTTG 1 -- ds50010--------
    rs1480828411,2
    		C,--102330429(+) ATGCTA/GTTTTT 1 -- ds50010--------
    rs2021048871,2
    		--102330434(+) TTTTT-/CCCCCA 1 -- ds50010--------
    rs1418227791,2
    		--102330655(+) TCTAGC/GATTTC 1 -- ds50010--------
    rs735239931,2
    		C,--102330685(+) TTTGAC/ATATCC 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs735239941,2
    		C,--102331062(+) TGGCCG/AAGAGG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs37472981,2
    		C,F,H,--102331106(+) CGGAAA/GCCCAA 1 -- int19Minor allele frequency- G:0.89NA NS EA 636
    rs1810058711,2
    		C,--102331170(+) TCACCC/TTGGGC 1 -- ut310--------
    rs1849838131,2
    		--102331416(+) TGTGAA/CAGGAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for NXF3 (102330738 - 102348157 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for NXF3
         1 CNV: 96860
         1 Indel: 83655
    Human Gene Mutation Database (HGMD): NXF3

    Locus Specific Mutation Databases (LSDB): NXF3

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NXF3
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    Disorders / Diseases
    for NXF3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NXF3 for disorders           About GeneDecksing

    OMIM gene information: 300316    OMIM disorders: --

    2 diseases for NXF3:    About MalaCards
    pelizaeus-merzbacher disease    influenza

    1 disease from the University of Copenhagen DISEASES database for NXF3:
    Pelizaeus-Merzbacher disease

    Export disorders for NXF3 gene to outside databases

    Publications
    for NXF3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NXF3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with NXF3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. (PubMed id 11073998)1, 2, 3, 9 Herold A.... Izaurralde E. (2000)
    2. Two closely related human nuclear export factors utilize entirely distinct export pathways. (PubMed id 11545741)1, 2, 9 Yang J.... Cullen B.R. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. (PubMed id 11566096)1, 2 Jun L.... Froyen G. (2001)
    5. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere s hortening. (PubMed id 22379092)1 Shamay M....Hayward S.D. (2012)
    6. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    7. Formation of a Tap/NXF1 Homotypic Complex Is Mediated through the Amino-Terminal Domain of Tap and Enhances Interaction with Nucleoporins. (PubMed id 17978099)1 Matzat L.H....Levesque L. (2008)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    External Searches for NXF3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
    OMIM
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    Genome Databases showing NXF3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56000 HGNC: 8073 AceView: NXF3 Ensembl:ENSG00000147206 euGenes: HUgn56000
    ECgene: NXF3 Kegg: 56000 H-InvDB: NXF3

    Other Databases showing NXF3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NXF3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NXF3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NXF3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NXF3 gene:
    Search GeneIP for patents involving NXF3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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