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NXF2B Gene

protein-coding   GIFtS: 41
GCID: GC0XM101615

Nuclear RNA Export Factor 2B

  Search for NXF2B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear RNA Export Factor 2B1 2     Nuclear RNA Export Factor 22
Cancer/Testis Antigen 392 3     CT393
TAP-Like Protein 22 3     TAPL-23
TCP11X12     TAPL23
bA353J17.12     

External Ids:    HGNC: 239841   Entrez Gene: 7283432   Ensembl: ENSG000001859457   UniProtKB: Q9GZY03   

Export aliases for NXF2B gene to outside databases

Previous GC identifer: GC0XM101503


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NXF2B Gene:
NXF2B (nuclear RNA export factor 2B) is a protein-coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is NXF1.

UniProtKB/Swiss-Prot: NXF2_HUMAN, Q9GZY0
Function: Involved in the export of mRNA from the nucleus to the cytoplasm




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the NXF2B gene promoter:
         STAT1   AML1a   GCNF   STAT1beta   GATA-1   STAT1alpha   CP2   HSF2   GCNF-1   GCNF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NXF2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NXF2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22.1

NXF2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NXF2B gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM101615:  view genomic region     (about GC identifiers)

Start:
101,615,316 bp from pter      End:
101,726,732 bp from pter
Size:
111,417 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NXF2_HUMAN, Q9GZY0 (See protein sequence)
Recommended Name: Nuclear RNA export factor 2  
Size: 626 amino acids; 71627 Da
Subunit: Interacts with NXT1, NXT2, E1B-AP5, the REF proteins and with nucleoporins, Nup62, Nup153 and Nup214
Sequence caution: Sequence=AAK31975.1; Type=Erroneous initiation; Sequence=BAA91154.1; Type=Erroneous initiation;
Sequence=CAB75659.1; Type=Miscellaneous discrepancy; Note=The sequence differs from that shown due to either
intron retention or a splicing event;
Secondary accessions: Q9BXU4 Q9NSS1 Q9NX66

Explore the universe of human proteins at neXtProt for NXF2B: NX_Q9GZY0

Explore proteomics data for NXF2B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NXF2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001093156.1  
    ENSEMBL proteins: 
     ENSP00000361838   ENSP00000361835   ENSP00000361836   ENSP00000396447   ENSP00000413087  

    NXF2B Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for NXF2B 

    NXF2B Antibody Products:

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    NXF2B Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for NXF2B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 7):
     IPR002075 NTF2
     IPR015245 Tap_RNA-bd
     IPR005637 TAP_C_dom
     IPR001611 Leu-rich_rpt
     IPR012677 Nucleotide-bd_a/b_plait

    Graphical View of Domain Structure for InterPro Entry Q9GZY0

    ProtoNet protein and cluster: Q9GZY0

    2 Blocks protein domains:
    IPB002075 Nuclear transport factor 2 (NTF2)
    IPB005637 TAP C-terminal domain


    UniProtKB/Swiss-Prot: NXF2_HUMAN, Q9GZY0
    Domain: The NTF2 domain heterodimerizes with NXT1 and NXT2. The formation of NXF1/NXT1 heterodimers is required
    for NXF2-mediated nuclear mRNA export
    Domain: The leucine-rich repeats and the NTF2-domain are essential for the export of mRNA from the nucleus
    Domain: The C-terminal fragment, containing the TAP domain (also called UBA-like domain) and part of the NTF2-like
    domain, named the NPC-binding domain, mediates direct interactions with nucleoporin-FG-repeats and is necessary
    and sufficient for localization of NXF2 to the nuclear rim
    Domain: The RNA-binding domain is a non-canonical RNP-type domain
    Similarity: Belongs to the NXF family
    Similarity: Contains 4 LRR (leucine-rich) repeats
    Similarity: Contains 1 NTF2 domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain
    Similarity: Contains 1 TAP-C domain


    Find genes that share domains with NXF2B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NXF2_HUMAN, Q9GZY0
    Function: Involved in the export of mRNA from the nucleus to the cytoplasm

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003723RNA binding NAS11073998
    GO:0005515protein binding ----
         
    Find genes that share ontologies with NXF2B           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NXF2B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NXF2B
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NXF2_HUMAN, Q9GZY0: Nucleus, nucleoplasm. Cytoplasm. Note=Localized in the nucleoplasm and at the nuclear
    envelope. Shuttles between the nucleus and the cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytoskeleton4
    cytosol3

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm ISS--
    GO:0015629actin cytoskeleton ----
    GO:0042272nuclear RNA export factor complex NAS11073998

    Find genes that share ontologies with NXF2B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NXF2B About    
    See pathways by source

    SuperPathContained pathways About
    1Influenza A
    Influenza A0.34
    Herpes simplex infection0.33
    2RNA transport
    RNA transport
    3Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes
    4mRNA surveillance pathway
    mRNA surveillance pathway


    Find genes that share SuperPaths with NXF2B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5 Kegg Pathways  (Kegg details for NXF2B):
        Ribosome biogenesis in eukaryotes
    RNA transport
    mRNA surveillance pathway
    Influenza A
    Herpes simplex infection

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NXF2B
    Interactions:

        Search GeneGlobe Interaction Network for NXF2B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NXF2B (Q9GZY03 ENSP000003618354) via UniProtKB, MINT, STRING, and/or I2D (see all 106)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUP153P497903I2D: score=1 
    NUP214P356583I2D: score=1 
    NUP62P371983I2D: score=1 
    NXF3ENSP000003785044STRING: ENSP00000378504
    NXF2ENSP000003618434STRING: ENSP00000361843
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006406mRNA export from nucleus NAS11073998
    GO:0006810transport ----
    GO:0007275multicellular organismal development ISS--
    GO:0050658RNA transport ISS--
    GO:0051028mRNA transport ----

    Find genes that share ontologies with NXF2B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NXF2B (NXF2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NXF2B gene: 
    NM_001099686.2  

    Unigene Cluster for NXF2B:

    Nuclear RNA export factor 2B
    Hs.648337  [show with all ESTs]
    Unigene Representative Sequence: BX647232
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372752(uc004eiz.4) ENST00000372749(uc004eiy.4) ENST00000372750
    ENST00000489531 ENST00000457521(uc022cav.1 uc004ejb.4) ENST00000412230(uc010nob.1)

    miRNA
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    Search for qRT-PCR Assays for microRNAs that regulate NXF2B
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NXF2B
    Predesigned siRNA for gene silencing in human, mouse, rat NXF2B
    Clone
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    GenScript: all cDNA clones in your preferred vector: NXF2B (NM_001099686)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NXF2B
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      Search QuantiTect SYBR Green Assays in human, mouse, rat NXF2B
      QuantiFast Probe-based Assays in human, mouse, rat NXF2B

    Additional mRNA sequence: 

    AF285596.1 AK000423.1 AK308255.1 BX647232.1 

    4 DOTS entries:

    DT.103434  DT.121307672  DT.95341451  DT.95367446 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NXF2B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                -                                                                                                                     
    SP2:                                -                                                                                                                     
    SP3:              -                 -                                                                                                                     
    SP4:                                                                                                                                                      


    ECgene alternative splicing isoforms for NXF2B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NXF2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NXF2B Expression
    About this image

    NXF2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NXF2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.648337

    UniProtKB/Swiss-Prot: NXF2_HUMAN, Q9GZY0
    Tissue specificity: Expressed almost exclusively in testis. Also expressed in several cancers

        Custom PCR Arrays for NXF2B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NXF2B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NXF2B gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nxf21 nuclear RNA export factor 2 70.93(n)
    57.85(a)
      83454  NM_031259.1  NP_112549.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta sbr6
    Nxf36
    (see all 3)
    Nuclear export factor 3
    (see all 3)
    25(a)
    21(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(10726785-10741125)
    3L(13958303-13965106)
    worm
    (Caenorhabditis elegans)
    Secernentea nxf-26
    nxf-16
    Protein NXF-1, isoform a
    26(a)
    25(a)
    many ↔ many
    many ↔ many
    V(14416115-14417829) WBGene00003835
    V(14412405-14415792) WBGene00003834


    ENSEMBL Gene Tree for NXF2B (if available)
    TreeFam Gene Tree for NXF2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NXF2B gene
    NXF21 2  NXF12  NXF32  NXF52  
    5 SIMAP similar genes for NXF2B using alignment to 3 protein entries:     NXF2_HUMAN (see all proteins):
    NXF2    NXF5    NXF1    DKFZp667O0311    NXF3

    Find genes that share paralogs with NXF2B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NXF2B (see all 503)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1119238421,2
    C--91301721(+) AATAAA/GACTTC 1 -- int10--------
    rs5004791,2
    C,F--91301984(-) AGTGTC/TAGGCT 1 -- int14Minor allele frequency- T:0.33NA WA 6
    rs556531891,2
    C--91304507(-) ACAGGA/GGCAAA 1 -- int10--------
    rs1123559281,2
    C--91307610(+) TATATC/TTTATT 1 -- int10--------
    rs5400481,2
    C--91308039(-) GAGTCT/CTCTGA 1 -- int14Minor allele frequency- C:0.00NA WA 6
    rs1493149451,2
    C--91308606(-) CTCACA/GCCAAA 1 -- int10--------
    rs1822163451,2
    --91308607(-) TCTCAC/TGCCAA 1 -- int10--------
    rs1912676241,2
    --91308654(-) CACTTA/GGCCCT 1 -- int10--------
    rs4933121,2
    C,F--91309183(+) gtcagC/Aaagat 1 -- int15Minor allele frequency- A:0.50NA WA 8
    rs3735934991,2
    C--91309183(-) ATCTTG/TTGACA 1 -- int10--------

    HapMap Linkage Disequilibrium report for NXF2B (101615316 - 101726732 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NXF2B: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NXF2B
    DNA2.0 Custom Variant and Variant Library Synthesis for NXF2B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for NXF2B:
    Male infertility

    Find genes that share disorders with NXF2B           About GenesLikeMe

    Genetic Association Database (GAD): NXF2B

    Export disorders for NXF2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NXF2B gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with NXF2B)
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    1. Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome. (PubMed id 16382448)1, 3 Chen Y.-T....Jongeneel C.V. (Genes Chromosomes Cancer 2006)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. (PubMed id 12704671)1, 2 Loriot A.... De Smet C. (Int. J. Cancer 2003)
    6. NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. (PubMed id 11566096)1, 2 Jun L.... Froyen G. (Curr. Biol. 2001)
    7. An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2 Wang P.J.... Page D.C. (Nat. Genet. 2001)
    8. TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. (PubMed id 11073998)1, 2 Herold A.... Izaurralde E. (Mol. Cell. Biol. 2000)
    9. Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export. (PubMed id 10567585)1, 2 Black B.E.... Paschal B.M. (Mol. Cell. Biol. 1999)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 728343 HGNC: 23984 Ensembl:ENSG00000185945 euGenes: HUgn728343 ECgene: NXF2B Kegg: 728343
    H-InvDB: NXF2B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NXF2B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NXF2B gene:
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    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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