NVL Gene
protein-coding GIFtS: 57
GCID: GC01M224416
|
|
nuclear VCP-like
| |
Aliases for NVL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Nuclear VCP-Like1 2 | | NVLp2 3 | | Nuclear Valosin-Containing Protein-Like2 | | Nuclear VCP-Like Protein3 |
Export aliases for NVL gene to outside databasesPrevious GC identifers: GC01M222845 GC01M220232 GC01M220822 GC01M221389 GC01M220721 GC01M222482 GC01M194934 |
Summaries for NVL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for NVL: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multipletranscript variants encoding different isoforms have been found for this gene. Two encoded proteins, described asmajor and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (majorisoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983,16782053), while the minor isoform has been localized to the nucleoplasmin. (provided by RefSeq, Aug 2011) Gene Wiki entry for NVL
|
Genomic Views for NVL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NVL gene promoter: AREB6 Pbx1a LCR-F1 Other transcription factors
Search SABiosciences Chromatin IP Primers for NVL
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NVL |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q41-q42.2 Ensembl cytogenetic band: 1q42.11 HGNC cytogenetic band: 1q41-q42.2NVL Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M224416: view genomic region
(about GC identifiers)
Start:
|
224,415,036 bp from pter |
End:
|
224,518,089 bp from pter |
Size:
|
103,054 bases |
Orientation:
|
minus strand |
|
Proteins for NVL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: NVL_HUMAN, O15381 (See
protein sequence)Recommended Name: Nuclear valosin-containing protein-like Size: 856 amino acids; 95051 Da
Subunit: Interacts with NCL/nucleolin
Subcellular location: Nucleus, nucleolus
1 PDB 3D structure from and Proteopedia for NVL:2X8A (3D)
 
Secondary accessions: B4DMC4 B4DP98 Q96EM7Alternative splicing: 5 isoforms: O15381-1 O15381-2 O15381-3 O15381-4 O15381-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NVL: NX_O15381
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15381 NVL Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (4 alternative transcripts):
NP_001230075.1 NP_001230076.1 NP_002524.2 NP_996671.1 ENSEMBL proteins: ENSP00000281701 ENSP00000375747 ENSP00000419420 ENSP00000417826 ENSP00000417213 ENSP00000419930 ENSP00000418380 ENSP00000419828 ENSP00000394884 ENSP00000419586 ENSP00000418085 ENSP00000341362 ENSP00000354779 Human Recombinant Protein Products for NVL:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
NVL for ontologies About GeneDecksing
NVL Antibody Products: Assay Products for NVL: |
Protein
Domains / Families for NVL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NVL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15381ProtoNet protein and cluster: O15381 UniProtKB/Swiss-Prot: NVL_HUMAN, O15381Similarity: Belongs to the AAA ATPase family |
Function for NVL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: Genatlas biochemistry entry for NVL:nuclear valosin containing protein like 1,with two alternatively spliced forms NVL1,83kDa,not phosphorylated,NVL2phosphorylated,95-110kDa
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- | | GO:0017111 | nucleoside-triphosphatase activity |
IEA | -- |
NVL for ontologies About GeneDecksing
Phenotypes: 3 GenomeRNAi human phenotypes for NVL: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NVL (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NVL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NVL (NM_002533) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NVL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NVL  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NVL |
|
Pathways & Interactions for NVL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ribosome biogenesis in eukaryotes | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Kegg Pathway (Kegg details for NVL):
NVL for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NVL
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/103 Interacting proteins for NVL (O153812, 3 ENSP000002817014) via UniProtKB, MINT, STRING, and/or I2D (see all 103)About this table
|
Drugs & Compounds for NVL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for NVL Search CenterWatch for drugs/clinical trials and news about NVL 
|
Transcripts for NVL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for NVL gene (4 alternative transcripts): NM_001243146.1 NM_001243147.1 NM_002533.3 NM_206840.2 Unigene Cluster for NVL: Nuclear VCP-like Hs.497867 [show with all ESTs]Unigene Representative Sequence: NM_00253318/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25): ENST00000281701(uc001hok.3 uc001hol.3 uc010pvd.2 uc010pve.2 uc010pvf.2) ENST00000391875 ENST00000469968 ENST00000481213 ENST00000483094 ENST00000489194 ENST00000493060 ENST00000469075 ENST00000482491 ENST00000496393 ENST00000462893 ENST00000467882 ENST00000492281 ENST00000488718 ENST00000436927 ENST00000470989 ENST00000470903 ENST00000461466
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NVL (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NVL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NVL (NM_002533) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NVL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NVL  |
Additional cDNA sequence: AF401208.1 AK293923.1 AK297070.1 AK297396.1 AK298244.1 AK298826.1 BC005897.1 BC012105.1 U68140.1 U78772.1 20 DOTS entries: DT.442615 DT.100026180 DT.100666554 DT.100026181 DT.95161233 DT.100796771 DT.100796773 DT.121430114 DT.100796768 DT.121430129 DT.92431595 DT.92431601 DT.95161234 DT.100026182 DT.121430166 DT.121430176 DT.121430187 DT.97790989 DT.100799980 DT.121430144 24/151 AceView cDNA sequences (see all 151): NM_206840 BX508792 BM979309 BU182097 BQ949149 BQ919152 BQ129367 BU683548 AW136416 CA389622 BM693264 NM_002533 BM793828 CA488893 BE254577 AF401208 BQ028394 BC012105 BM668588 BF001473 CB160823 BM970938 AI955163 CA425331 GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for NVL (see all 17) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | · | 7f | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for NVL
|
Expression for NVL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NVL expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TAAACATTTT
 About this image See NVL Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NVL
SOURCE GeneReport for Unigene cluster: Hs.497867
UniProtKB/Swiss-Prot: NVL_HUMAN, O15381Tissue specificity: Widely expressed. Highest level of expression in heart, placenta, skeletal muscle, pancreas andretina SABiosciences Custom PCR Arrays for NVL
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NVL Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NVL | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NVL | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NVL | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NVL |
Orthologs for NVL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NVL gene from 9/32 species (see all 32) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
NVL1 |
nuclear VCP-like |
72.74(n) 76.43(a) |
  |
421326 NM_001079576.2 NP_001073044.2 |
lizard (Anolis carolinensis) |
Reptilia |
NVL6 |
-- |
72(a) |
1 ↔ 1 |
1(252724599-252769158) |
African clawed frog (Xenopus laevis) |
Amphibia |
MGC529792 |
hypothetical protein MGC52979 |
75(n) |
  |
BC044980.1 |
zebrafish (Danio rerio) |
Actinopterygii |
BC044464.12 |
-- |
74.68(n) |
  |
BC044464.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
smid1 , 3 |
adenosinetriphosphatase3 smallminded1 |
55(a)3 59.37(n)1 57.1(a)1 |
  |
3 65F103 388241 NM_079235.31 NP_523959.21 |
worm (Caenorhabditis elegans) |
Secernentea |
mac-11 , 3 |
Protein MAC-11 |
50(a)3 57.25(n)1 55.44(a)1 |
  |
II(13311493-13320802)3 1749741 NM_064413.61 NP_496814.11 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
RIX7(YLL034C)4 RIX71 |
Putative ATPase of the AAA family, required for export more4 Rix7p1 |
53.39(n)1 51.02(a)1 |
  |
12(73146-70633)4 8506251, 4 NP_013066.11, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
CDC48C1 |
cell division cycle 48C protein |
50.81(n) 41.77(a) |
  |
821105 NM_111027.3 NP_186810.2 |
rice (Oryza sativa) |
Liliopsida |
Os06g01094001 |
hypothetical protein |
54.21(n) 47.86(a) |
  |
4339880 NM_001063111.1 NP_001056576.1 |
ENSEMBL Gene Tree for NVL (if available) TreeFam Gene Tree for NVL (if available)  |
Paralogs for NVL gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for NVL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for NVL (224415036 - 224518089 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for NVL 1 CNV: 31690  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NVL |
|
Disorders
/ Diseases for NVL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NVL for disorders About GeneDecksing
OMIM gene information: 602426
OMIM disorders: --
3 diseases for NVL: About MalaCardshermaphroditism tuberculosis mycobacterium tuberculosis Human Genome Epidemiology (HuGE) Navigator: NVL (2 documents) Export disorders for NVL gene to outside databases
|
Publications for NVL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NVL gene, integrated from 9 sources (see all 29): (articles sorted by number of sources associating them with NVL) | |  | Utopia: connect your pdf to the dynamic world of online information |
- NVL: a new member of the AAA family of ATPases localized to the nucleus. (PubMed id 9286697)1, 2, 3, 9 Germain-Lee E.L.... Valle D. (1997)
- Structure and function of the N-terminal nucleolin bi nding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nu cleolar localization signal. (PubMed id 21474449)1, 2 Fujiwara Y....Hiroaki H. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- The AAA-ATPase NVL2 is a telomerase component essentia l for holoenzyme assembly. (PubMed id 22226966)1 Her J. and Chung I.K. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for NVL gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing NVL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NVL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NVL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for NVL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NVL gene: Search GeneIP for patents involving NVL
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for NVL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for NVL | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NVL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NVL | | OriGene Protein Over-expression Lysate for NVL | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for NVL | | OriGene 3'-UTR Clone for NVL | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NVL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NVL | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for NVL | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for NVL | | OriGene Custom Protein Services for NVL | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NVL | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NVL | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NVL | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NVL | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NVL | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NVL |
| |
 |  |  |  | |
| | | Search Tocris compounds for NVL |
| |  |  |  |  | | | | |
 |
 |
 |
 | | NVL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NVL |
|  |  |  |  | | | Search ThermoFisher Antibodies for NVL |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NVL |
| |  | |
|
|
|