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Aliases for NUTM2D Gene

Aliases for NUTM2D Gene

  • NUT Family Member 2D 2 3 5
  • Family With Sequence Similarity 22, Member D 2 3
  • FAM22D 3 4
  • NUT Family Member 2A Pseudogene 3
  • Protein FAM22D 3

External Ids for NUTM2D Gene

Previous HGNC Symbols for NUTM2D Gene

  • FAM22D

Previous GeneCards Identifiers for NUTM2D Gene

  • GC10P089120
  • GC10P089124

Summaries for NUTM2D Gene

GeneCards Summary for NUTM2D Gene

NUTM2D (NUT Family Member 2D) is a Protein Coding gene. An important paralog of this gene is NUTM2A.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2D Gene

Genomics for NUTM2D Gene

Regulatory Elements for NUTM2D Gene

Enhancers for NUTM2D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G087341 1 ENCODE 12.3 -15.0 -14962 2.0 ATF1 CREB3L1 SIN3A ZNF2 ZNF121 GLIS2 ZNF143 SP3 YY2 REST NUTM2D NUTM2A NUTM2A-AS1 PIR41183
GH10G087142 1.1 Ensembl ENCODE 9.9 -215.0 -214982 1.0 HDGF FOXA2 PKNOX1 BMI1 ZBTB40 ETV6 FOS RELB CREM IKZF2 CFL1P1 NUTM2D NUTM2A FAM35A NUTM2A-AS1 RN7SL733P ENSG00000237280
GH10G087024 1.1 Ensembl ENCODE 9.9 -331.8 -331842 1.8 HDAC1 GATA2 FOS EGR2 ZBTB2 ELF4 ELF1 MTA1 SMARCA4 ZBTB26 NUTM2D PAPSS2 GLUD1 ENSG00000271573 FAM25A
GH10G087090 0.7 Ensembl ENCODE 10.9 -267.2 -267168 0.2 TGIF2 SAP130 RBFOX2 NUTM2D FAM35A GC10M087058
GH10G087081 1.1 Ensembl ENCODE 6.8 -274.1 -274147 4.2 FOXA2 BMI1 RARA YY1 ZNF121 FOS RELB IKZF2 ZNF362 JUNB MMRN2 ADIRF SNCG FAM35A NUTM2A-AS1 OPN4 NUTM2D GC10M087058
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NUTM2D on UCSC Golden Path with GeneCards custom track

Genomic Location for NUTM2D Gene

Chromosome:
10
Start:
87,357,668 bp from pter
End:
87,370,695 bp from pter
Size:
13,028 bases
Orientation:
Plus strand

Genomic View for NUTM2D Gene

Genes around NUTM2D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2D Gene

Proteins for NUTM2D Gene

  • Protein details for NUTM2D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VT03-NTM2D_HUMAN
    Recommended name:
    NUT family member 2D
    Protein Accession:
    Q5VT03
    Secondary Accessions:
    • A6NGV9

    Protein attributes for NUTM2D Gene

    Size:
    806 amino acids
    Molecular mass:
    86276 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NUTM2D Gene

Post-translational modifications for NUTM2D Gene

No Post-translational modifications

Other Protein References for NUTM2D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2D Gene

Domains & Families for NUTM2D Gene

Protein Domains for NUTM2D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUTM2D Gene

Graphical View of Domain Structure for InterPro Entry

Q5VT03

UniProtKB/Swiss-Prot:

NTM2D_HUMAN :
  • Belongs to the NUT family.
Family:
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2D: view

No data available for Gene Families for NUTM2D Gene

Function for NUTM2D Gene

Animal Model Products

miRNA for NUTM2D Gene

miRTarBase miRNAs that target NUTM2D

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2D Gene

Localization for NUTM2D Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUTM2D gene
Compartment Confidence
plasma membrane 3
cytosol 2
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NUTM2D Gene

Pathways & Interactions for NUTM2D Gene

SuperPathways for NUTM2D Gene

No Data Available

Interacting Proteins for NUTM2D Gene

Gene Ontology (GO) - Biological Process for NUTM2D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NUTM2D Gene

Drugs & Compounds for NUTM2D Gene

No Compound Related Data Available

Transcripts for NUTM2D Gene

mRNA/cDNA for NUTM2D Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NUTM2D Gene

NUT family member 2D:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2D Gene

No ASD Table

Relevant External Links for NUTM2D Gene

GeneLoc Exon Structure for
NUTM2D
ECgene alternative splicing isoforms for
NUTM2D

Expression for NUTM2D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUTM2D Gene

NURSA nuclear receptor signaling pathways regulating expression of NUTM2D Gene:

NUTM2D

SOURCE GeneReport for Unigene cluster for NUTM2D Gene:

Hs.701044
genes like me logo Genes that share expression patterns with NUTM2D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUTM2D Gene

Orthologs for NUTM2D Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2D Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 35
  • 36 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 36 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 36 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 34 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm806 35
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 44 (a)
OneToMany
Species where no ortholog for NUTM2D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2D Gene

ENSEMBL:
Gene Tree for NUTM2D (if available)
TreeFam:
Gene Tree for NUTM2D (if available)

Paralogs for NUTM2D Gene

Paralogs for NUTM2D Gene

(7) SIMAP similar genes for NUTM2D Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for NUTM2D Gene

genes like me logo Genes that share paralogs with NUTM2D: view

Variants for NUTM2D Gene

Sequence variations from dbSNP and Humsavar for NUTM2D Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000000514 -- 87,369,855(+) CCCTT(A/C/T)ACCAT nc-transcript-variant
rs1001600261 -- 87,371,019(+) CATTA(A/G)ATACT downstream-variant-500B
rs1003683185 -- 87,358,579(+) ACCTG(C/G)GGATG intron-variant
rs1004243188 -- 87,361,200(+) GCATT(-/G)GGAGC intron-variant
rs1005831300 -- 87,357,036(+) CGACA(C/G)GGTGT nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for NUTM2D Gene

Variant ID Type Subtype PubMed ID
dgv492n106 CNV duplication 24896259
dgv949n100 CNV gain 25217958
esv2759774 CNV gain+loss 17122850
esv2760108 CNV gain+loss 21179565
esv2764246 CNV gain+loss 21179565
esv27973 CNV gain+loss 19812545
esv3577605 CNV gain 25503493
esv3624105 CNV loss 21293372
esv3891880 CNV gain 25118596
nsv1128647 CNV duplication 24896259
nsv428236 CNV loss 18775914
nsv482148 CNV gain 20164927
nsv498736 CNV loss 21111241
nsv7207 OTHER inversion 18451855
nsv7483 CNV deletion 18451855
nsv948123 CNV duplication 23825009

Variation tolerance for NUTM2D Gene

Gene Damage Index Score: 12.99; 94.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NUTM2D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUTM2D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUTM2D Gene

Disorders for NUTM2D Gene

Relevant External Links for NUTM2D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NUTM2D

No disorders were found for NUTM2D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUTM2D Gene

Publications for NUTM2D Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64

Products for NUTM2D Gene

Sources for NUTM2D Gene

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