Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NUTM2B Gene

Aliases for NUTM2B Gene

  • NUT Family Member 2B 2 3 5
  • Family With Sequence Similarity 22, Member B 2 3
  • FAM22B 3 4
  • Protein FAM22B 3
  • BA119F19.1 3

External Ids for NUTM2B Gene

Previous HGNC Symbols for NUTM2B Gene

  • FAM22B

Previous GeneCards Identifiers for NUTM2B Gene

  • GC10P081479
  • GC10P081573
  • GC10P080039
  • GC10P080065

Summaries for NUTM2B Gene

GeneCards Summary for NUTM2B Gene

NUTM2B (NUT Family Member 2B) is a Protein Coding gene. Diseases associated with NUTM2B include endometrial stromal sarcoma. An important paralog of this gene is NUTM2G.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUTM2B Gene

Genomics for NUTM2B Gene

Genomic Location for NUTM2B Gene

Chromosome:
10
Start:
79,699,700 bp from pter
End:
79,715,486 bp from pter
Size:
15,787 bases
Orientation:
Plus strand

Genomic View for NUTM2B Gene

Genes around NUTM2B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUTM2B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUTM2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUTM2B Gene

No data available for Regulatory Elements for NUTM2B Gene

Proteins for NUTM2B Gene

  • Protein details for NUTM2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNL0-NTM2B_HUMAN
    Recommended name:
    NUT family member 2B
    Protein Accession:
    A6NNL0
    Secondary Accessions:
    • A6NM73

    Protein attributes for NUTM2B Gene

    Size:
    878 amino acids
    Molecular mass:
    93984 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAQ08562.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ08563.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for NUTM2B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NUTM2B Gene

Proteomics data for NUTM2B Gene at MOPED

Post-translational modifications for NUTM2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NUTM2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUTM2B Gene

Domains & Families for NUTM2B Gene

Protein Domains for NUTM2B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUTM2B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NNL0

UniProtKB/Swiss-Prot:

NTM2B_HUMAN :
  • Belongs to the NUT family.
Family:
  • Belongs to the NUT family.
genes like me logo Genes that share domains with NUTM2B: view

No data available for Gene Families for NUTM2B Gene

Function for NUTM2B Gene

miRNA for NUTM2B Gene

miRTarBase miRNAs that target NUTM2B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUTM2B Gene

Localization for NUTM2B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NUTM2B Gene

Pathways & Interactions for NUTM2B Gene

SuperPathways for NUTM2B Gene

No Data Available

Interacting Proteins for NUTM2B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000394623%0d%0a9606.ENSP00000244769%0d%0a
Selected Interacting proteins: ENSP00000394623 for NUTM2B Gene via STRING

Symbol External ID(s) Details
ATXN1

Gene Ontology (GO) - Biological Process for NUTM2B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NUTM2B Gene

Drugs & Compounds for NUTM2B Gene

No Compound Related Data Available

Transcripts for NUTM2B Gene

mRNA/cDNA for NUTM2B Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NUTM2B Gene

No ASD Table

Relevant External Links for NUTM2B Gene

GeneLoc Exon Structure for
NUTM2B
ECgene alternative splicing isoforms for
NUTM2B

Expression for NUTM2B Gene

mRNA expression in normal human tissues for NUTM2B Gene

genes like me logo Genes that share expression patterns with NUTM2B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NUTM2B Gene

Orthologs for NUTM2B Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUTM2B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NUTM2D 35
  • 70.33 (n)
  • 55.06 (a)
-- 36
  • 46 (a)
OneToMany
dog
(Canis familiaris)
Mammalia NUTM2G 35
  • 67.74 (n)
  • 53.85 (a)
-- 36
  • 50 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm806 35
  • 58.5 (n)
  • 41.88 (a)
Nutm2 16
Gm806 36
  • 39 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC738010 35
  • 98.79 (n)
  • 97.72 (a)
-- 36
  • 98 (a)
ManyToMany
-- 36
  • 97 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Nutm2f 35
  • 58.45 (n)
  • 42.44 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 39 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 36 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 48 (a)
OneToMany
Species with no ortholog for NUTM2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NUTM2B Gene

ENSEMBL:
Gene Tree for NUTM2B (if available)
TreeFam:
Gene Tree for NUTM2B (if available)

Paralogs for NUTM2B Gene

Paralogs for NUTM2B Gene

(7) SIMAP similar genes for NUTM2B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NUTM2B: view

Variants for NUTM2B Gene

Variation tolerance for NUTM2B Gene

Gene Damage Index Score: 4.28; 62.71% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NUTM2B Gene

HapMap Linkage Disequilibrium report
NUTM2B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NUTM2B Gene

Disorders for NUTM2B Gene

MalaCards: The human disease database

(1) MalaCards diseases for NUTM2B Gene - From: Orphanet and DISEASES

Disorder Aliases PubMed IDs
endometrial stromal sarcoma
  • endometrial stromal sarcoma, high grade
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for NUTM2B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NUTM2B
genes like me logo Genes that share disorders with NUTM2B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for NUTM2B Gene

Publications for NUTM2B Gene

  1. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3 67

Products for NUTM2B Gene

Sources for NUTM2B Gene

Back to Top

Content