Aliases for NUTF2 Gene
External Ids for NUTF2 Gene
Previous GeneCards Identifiers for NUTF2 Gene
This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]
GeneCards Summary for NUTF2 Gene
NUTF2 (Nuclear Transport Factor 2) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling. GO annotations related to this gene include transporter activity and Ran GTPase binding.
UniProtKB/Swiss-Prot for NUTF2 Gene
Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.