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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUSAP1 Gene

protein-coding   GIFtS: 46
GCID: GC15P041624

nucleolar and spindle associated protein 1
 Explore 1 disease affiliated with
NUSAP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NUSAP1    

Aliases
for NUSAP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nucleolar And Spindle Associated Protein 11 2     NUSAP2 5
ANKT1 2 3 5     FLJ134211
BM0371 2     NuSAP11
LNP1 2     Nucleolar And Spindle-Associated Protein 12
PRO0310p11 2     Nucleolar Protein ANKT2
Q03101 2     NuSAP3
SAPL1 2     

External Ids:    HGNC: 185381   Entrez Gene: 512032   Ensembl: ENSG000001378047   OMIM: 6128185   UniProtKB: Q9BXS63   

Export aliases for NUSAP1 gene to outside databases

Previous GC identifers: GC15P039341 GC15P039412 GC15P018473


Summaries
for NUSAP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NUSAP1:
NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et
al., 2003 (PubMed 12963707)).(supplied by OMIM, Jun 2009)

UniProtKB/Swiss-Prot: NUSAP_HUMAN, Q9BXS6
Function: Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May
associate with chromosomes and promote the organization of mitotic spindle microtubules around them




Genomic Views
for NUSAP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUSAP1 gene promoter:
         Bach1   Pax-5   Bach2   MyoD   AREB6   FOXO4   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NUSAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUSAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUSAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q14

NUSAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUSAP1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P041624:  view genomic region     (about GC identifiers)

Start:
 41,624,892 bp from pter      End:
 41,673,248 bp from pter
Size:
 48,357 bases      Orientation:
 plus strand

Proteins
for NUSAP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NUSAP_HUMAN, Q9BXS6 (See protein sequence)
Recommended Name: Nucleolar and spindle-associated protein 1  
Size: 441 amino acids; 49452 Da
Subunit: Interacts with DNA and microtubules. Microtubule bundling is inhibited by IPO7, KPNA2 and KPNB1 while
association with DNA is also inhibited by IPO7 and KPNA2 (By similarity)
Subcellular location: Cytoplasm (By similarity). Nucleus, nucleolus (By similarity). Cytoplasm, cytoskeleton, spindle
(By similarity). Chromosome (By similarity). Note=Found in the cytoplasm and nucleolus during interphase and
redistributes to the mitotic spindle in prometaphase (By similarity). Localizes to the mitotic spindle during anaphase
and telophase then disappears from around the chromosomes during cytokinesis (By similarity). Localizes to multiple
distinct regions of chromosomes throughout mitosis
Sequence caution: Sequence=AAF24034.1; Type=Frameshift; Positions=205; Sequence=AAF67624.1; Type=Frameshift;
Positions=175, 205; Sequence=AAH12887.2; Type=Erroneous initiation;
Secondary accessions: Q53GW2 Q8TBT4 Q96E58 Q96FJ1 Q9GZM9 Q9NZ85 Q9UI70
Alternative splicing: 5 isoforms:  Q9BXS6-1   Q9BXS6-2   Q9BXS6-3   Q9BXS6-4   Q9BXS6-5   

Explore the universe of human proteins at neXtProt for NUSAP1: NX_Q9BXS6

Post-translational modifications:

  • Ubiquitinated. Ubiquitination by FZR1 may lead to proteasome-dependent degradation of this protein1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BXS6

    • NUSAP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001230071.1  NP_001230072.1  NP_001230073.1  NP_057443.2  NP_060924.4  

    ENSEMBL proteins: 
     ENSP00000260359   ENSP00000452725   ENSP00000401014   ENSP00000453403   ENSP00000400746  
     ENSP00000454097   ENSP00000453657   ENSP00000453428   ENSP00000453558   ENSP00000401351  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NUSAP1

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005694chromosome IEA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005819spindle ----


    NUSAP1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NUSAP1

    Protein Domains /
    Families
    for NUSAP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NUSAP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026756 NuSAP

    Graphical View of Domain Structure for InterPro Entry Q9BXS6

    ProtoNet protein and cluster: Q9BXS6

    UniProtKB/Swiss-Prot: NUSAP_HUMAN, Q9BXS6
    Domain: The KEN box is required for the FZR1-dependent degradation of this protein subsequent to ubiquitination
    Similarity: Belongs to the NUSAP family


    Function
    for NUSAP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NUSAP_HUMAN, Q9BXS6
    Function: Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May
    associate with chromosomes and promote the organization of mitotic spindle microtubules around them

    miRNA
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    hsa-miR-587
    SwitchGear 3'UTR luciferase reporter plasmid: NUSAP1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for NUSAP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUSAP1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0008017microtubule binding IEA--


    NUSAP1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Nusap1tm1.1Gcm for NUSAP1
         4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Nusap1):
     cellular  embryogenesis  growth/size  mortality/aging 

    NUSAP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NUSAP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUSAP1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for NUSAP1 (Q9BXS63 ENSP000002603594) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KHDRBS2Q5VWX13, ENSP000002811564I2D: score=1 STRING: ENSP00000281156
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000070mitotic sister chromatid segregation IDA12963707
    GO:0000281cytokinesis after mitosis IDA12963707
    GO:0007076mitotic chromosome condensation IDA12963707
    GO:0040001establishment of mitotic spindle localization IDA12963707
    GO:0045840positive regulation of mitosis IDA12963707


    NUSAP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NUSAP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUSAP1
    Search CenterWatch for drugs/clinical trials and news about NUSAP1 / NUSAP 

    Transcripts
    for NUSAP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NUSAP1 gene (6 alternative transcripts): 
    NM_001129897.1  NM_001243142.1  NM_001243143.1  NM_001243144.1  NM_016359.4  NM_018454.7  

    Unigene Cluster for NUSAP1:

    Nucleolar and spindle associated protein 1
    Hs.615092  [show with all ESTs]
    Unigene Representative Sequence: NM_016359
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000558123 ENST00000260359(uc001znr.4 uc001zns.4 uc001znt.4 uc001znv.4 uc001znu.4)
    ENST00000559046 ENST00000450592 ENST00000559596 ENST00000414849 ENST00000558582
    ENST00000560747 ENST00000559659 ENST00000560177(uc001znw.4) ENST00000557840
    ENST00000560898 ENST00000560318 ENST00000450318(uc010ucw.2 uc010bce.3)


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUSAP1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate NUSAP1:
    hsa-miR-587
    SwitchGear 3'UTR luciferase reporter plasmid: NUSAP1 3' UTR sequence
    Inhib. RNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUSAP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUSAP1

    Additional cDNA sequence: 

    AF090915.1 AF217513.1 AF290612.1 AF305711.1 AK023483.1 AK222819.1 AK225703.1 AK290879.1 
    AK293168.1 AK307728.1 AL833611.1 BC001308.1 BC010838.1 BC011008.1 BC012887.1 BC024772.1 

    20 DOTS entries:

    DT.116010  DT.95330776  DT.97859449  DT.92342790  DT.91860885  DT.121026182  DT.121026205  DT.121026183 
    DT.92449985  DT.100801818  DT.95069470  DT.100037719  DT.100758033  DT.95069475  DT.121026193  DT.92449984 
    DT.121026172  DT.121026179  DT.91829098  DT.92053676 

    24/320 AceView cDNA sequences (see all 320):

    BP366015 AA732728 AF075355 BC001308 CB215384 BQ774867 BM792731 AA678631 
    F04726 CR605213 AA872316 CR623224 AA252105 CA412518 AA505133 BU860735 
    BX100702 BG251896 BU509626 BX375925 BQ421263 CR591711 AW074481 BM744638 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for NUSAP1 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c · 12d
    SP1:                                -                                   -     -                                             
    SP2:                                -                                   -     -                                             
    SP3:                                -                                   -     -                                             
    SP4:                                -                                   -     -                                             
    SP5:                                -     -                             -     -                                             


    ECgene alternative splicing isoforms for NUSAP1

    Expression
    for NUSAP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUSAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAATTGCCAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NUSAP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyMetanephrosKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E68 (Embryonic Progenitor Cell)
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)

    See NUSAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUSAP1

    SOURCE GeneReport for Unigene cluster: Hs.615092
        SABiosciences Custom PCR Arrays for NUSAP1
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    In Situ
    Assay Products:     
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    Orthologs
    for NUSAP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for NUSAP1 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nusap11 , 5 nucleolar and spindle associated protein 11, 5 77.29(n)1
    67.4(a)1    		   2 (59.97 cM)5
    1089071  NM_133851.31  NP_598612.11 
     1196182985 
    chicken
    (Gallus gallus)    		 Aves NUSAP11 nucleolar and spindle associated protein 1 57.6(n)
    47.52(a)    		   423213  NM_001031193.1  NP_001026364.1 
    lizard
    (Anolis carolinensis)    		 Reptilia NUSAP16
    		 --
    		 42(a)
    		 1 ↔ 1
    		 1(41737508-41752994)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.240262 Xenopus laevis transcribed sequence with weak similarity more 75.27(n)    BI477686.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii nusap11 nucleolar and spindle associated protein 1 48.01(n)
    39.47(a)    		   567446  NM_001145694.1  NP_001139166.1 


    ENSEMBL Gene Tree for NUSAP1 (if available)
    TreeFam Gene Tree for NUSAP1 (if available) 

    Paralogs
    for NUSAP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for NUSAP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/723 NCBI SNPs in NUSAP1 are shown (see all 723)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs30346111,2
    		C,--41626903(+) CTGGC-/TGTGTGT 5 -- int10--------
    rs592992201,2
    		C--41626904(+) TGTGT-/GTGTGTA 5 -- int11Minor allele frequency- GT:0.00NA 2
    rs1910316581,2
    		--41626993(+) CTCCCA/GCCACG 5 -- int10--------
    rs734049721,2
    		C,--41626997(+) CGCCAC/TGGCCT 5 -- int11Minor allele frequency- T:0.50WA 2
    rs1446146711,2
    		--41627035(+) CCCACC/GACGCC 5 -- int10--------
    rs1816645371,2
    		--41627256(+) AATAAA/GATGTT 5 -- int10--------
    rs591076121,2
    		C--41627473(+) TATAT-/TTAT  
                ATATT     		5 -- int10--------
    rs599722341,2
    		C,--41627559(+) AAAAT-/AAAC  
                TAAAT     		5 -- int10--------
    rs116313961,2
    		H--41627609(+) aatatA/Cctata 5 -- int10--------
    rs1484453851,2
    		--41627680(+) ATTTAG/TTGTGT 5 -- int10--------

    HapMap Linkage Disequilibrium report for NUSAP1 (41624892 - 41673248 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NUSAP1: --

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    Disorders / Diseases
    for NUSAP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NUSAP1 for disorders           About GeneDecksing

    OMIM gene information: 612818    OMIM disorders: --

    1 disease for NUSAP1:    About MalaCards
    lactose intolerance


    Export disorders for NUSAP1 gene to outside databases

    Publications
    for NUSAP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUSAP1 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with NUSAP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. (PubMed id 12963707)1, 2, 3 Raemaekers T.... Carmeliet G. (2003)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. SAP-like domain in nucleolar spindle associated prote in mediates mitotic chromosome loading as well as interphase chromatin interact ion. (PubMed id 21782797)1 Verbakel W....Engelborghs Y. (2011)
    7. Phosphorylation of NuSAP by Cdk1 regulates its interac tion with microtubules in mitosis. (PubMed id 22101338)1 Chou H.Y....Jeng Y.M. (2011)
    8. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)

    External Searches for NUSAP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
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    Genome Databases showing NUSAP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51203 HGNC: 18538 AceView: NUSAP1 Ensembl:ENSG00000137804 euGenes: HUgn51203
    ECgene: NUSAP1 H-InvDB: NUSAP1

    Other Databases showing NUSAP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NUSAP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUSAP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NUSAP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NUSAP1 gene:
    Search GeneIP for patents involving NUSAP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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