Aliases for NUS1 Gene
External Ids for NUS1 Gene
Previous Symbols for NUS1 Gene
GeneCards Summary for NUS1 Gene
NUS1 (Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog (S. Cerevisiae)) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring alkyl or aryl (other than methyl) groups.
UniProtKB/Swiss-Prot for NUS1 Gene
With DHDDS, forms the dehydrodolichyl diphosphate syntase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.