NUPR1L Gene
protein-coding GIFtS: 26
GCID: GC07M056185
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nuclear protein, transcriptional regulator, 1-like
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Aliases
for NUPR1L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nuclear Protein, Transcriptional Regulator, 1-Like1 2 | | Nuclear Transcriptional Regulator 1-Like Protein2 |
Export aliases for NUPR1L gene to outside databases |
Summaries
for NUPR1L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NUPR1L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_033968.6 NT_079592.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NUPR1L
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUPR1L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUPR1L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p11.2 Ensembl cytogenetic band: 7p11.2 HGNC cytogenetic band: 7p11.2NUPR1L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M056185: view genomic region
(about GC identifiers)
Start:
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56,182,374 bp from pter |
End:
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56,184,093 bp from pter |
Size:
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1,720 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 56,186,621-56,188,337 |
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Proteins
for NUPR1L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NUR1L_HUMAN, A6NF83 (See
protein sequence)Recommended Name: Nuclear transcriptional regulator 1-like protein Size: 97 amino acids; 11356 DaExplore the universe of human proteins at neXtProt for NUPR1L: NX_A6NF83
NUPR1L Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001139184.1
ENSEMBL proteins: ENSP00000455442
Human Recombinant Protein Products:
NUPR1L Antibody Products:
Assay Products for NUPR1L: |
Protein
Domains /
Families
for NUPR1L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUPR1L for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A6NF83ProtoNet protein and cluster: A6NF83 UniProtKB/Swiss-Prot: NUR1L_HUMAN, A6NF83Similarity: Belongs to the NUPR family |
Function
for NUPR1L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for NUPR1L | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUPR1L | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUPR1L |
|
Pathways & Interactions
for NUPR1L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUPR1L
|
Drugs & Compounds
for NUPR1L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NUPR1L
Search CenterWatch for drugs/clinical trials and news about NUPR1L / NUR1L
|
Transcripts
for NUPR1L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NUPR1L gene: NM_001145712.1 Unigene Cluster for NUPR1L: Nuclear protein, transcriptional regulator, 1-like Hs.177948 [show with all ESTs]Unigene Representative Sequence: BI8314861 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000329309(uc003tsb.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for NUPR1L | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUPR1L | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUPR1L |
Additional cDNA sequence: BC043523.1 1 DOTS entry: DT.75200104 6 AceView cDNA sequences: BC043523 BX439814 BI825227 BI831486 BX334917 BX439813
GeneLoc Exon Structure
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Expression
for NUPR1L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
SOURCE GeneReport for Unigene cluster: Hs.177948
SABiosciences Custom PCR Arrays for NUPR1L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUPR1L
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat NUPR1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUPR1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUPR1L |
Orthologs
for NUPR1L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NUPR1L gene from 1/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
nupr16 |
nuclear protein 1 |
35(a) |
1 ↔ 1 |
3(15109869-15110752) |
ENSEMBL Gene Tree for NUPR1L (if available)
TreeFam Gene Tree for NUPR1L (if available) |
Paralogs
for NUPR1L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NUPR1L gene
2 SIMAP similar genes for NUPR1L using alignment to 1 protein entry: NUR1L_HUMAN:LOC402280 NUPR1
NUPR1L for paralogs About GeneDecksing
5/7 Pseudogenes.org Pseudogenes for NUPR1L (see all 7)
PGOHUM00000262182 PGOHUM00000262422 PGOHUM00000262426 PGOHUM00000262457 PGOHUM00000262469
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Genomic Variants
for NUPR1L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for NUPR1L (56182374 - 56184093 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NUPR1L: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for NUPR1L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for NUPR1L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUPR1L gene integrated from 9 sources:
(articles sorted by number of sources associating them with NUPR1L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
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External Searches for NUPR1L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing NUPR1L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUPR1L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUPR1L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for NUPR1L gene:
Search GeneIP for patents involving NUPR1L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NUPR1L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NUPR1L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUPR1L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUPR1L | | | OriGene Protein Over-expression Lysate for NUPR1L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NUPR1L | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUPR1L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NUPR1L | | OriGene Custom Protein Services for NUPR1L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NUPR1L | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUPR1L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUPR1L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUPR1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUPR1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUPR1L |
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| | | | Search Tocris compounds for NUPR1L |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for NUPR1L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUPR1L |
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