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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUPL1 Gene

protein-coding   GIFtS: 56
GCID: GC13P025875

Nucleoporin Like 1

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleoporin Like 11 2
Nucleoporin-Like Protein 12 3
KIAA04103 5
PRO24632
Nucleoporin P58/P452

External Ids:    HGNC: 202611   Entrez Gene: 98182   Ensembl: ENSG000001394967   OMIM: 6076155   UniProtKB: Q9BVL23   

Export aliases for NUPL1 gene to outside databases

Previous GC identifers: GC13P019855 GC13P024805 GC13P023673 GC13P024773 GC13P006690


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUPL1 Gene:
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58.
The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules
entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate
transcriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq, Jul
2008)

GeneCards Summary for NUPL1 Gene: 
NUPL1 (nucleoporin like 1) is a protein-coding gene. Diseases associated with NUPL1 include influenza, and hepatitis, and among its related super-pathways are Interactions of Rev with host cellular proteins and HIV Life Cycle. GO annotations related to this gene include nucleocytoplasmic transporter activity.

UniProtKB/Swiss-Prot: NUPL1_HUMAN, Q9BVL2
Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear
membrane (By similarity)

Gene Wiki entry for NUPL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  NC_018924.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUPL1 gene promoter:
         STAT1   Pbx1a   POU6F1 (c2)   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Nkx2-5   POU3F2   En-1   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUPL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUPL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUPL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.13   Ensembl cytogenetic band:  13q12.13   HGNC cytogenetic band: 13q12.12

NUPL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUPL1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P025875:  view genomic region     (about GC identifiers)

Start:
25,875,662 bp from pter      End:
25,923,938 bp from pter
Size:
48,277 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUPL1_HUMAN, Q9BVL2 (See protein sequence)
Recommended Name: Nucleoporin p58/p45  
Size: 599 amino acids; 60897 Da
Subunit: Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1. Interacts with
NUTF2. Interacts with SRP1-alpha and Importin p97 proteins when they are together, but not with SRP1-alpha
protein alone (By similarity)
Subcellular location: Nucleus, nuclear pore complex (By similarity). Nucleus membrane; Peripheral membrane
protein; Cytoplasmic side (By similarity). Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By
similarity). Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the
transporter (By similarity)
Miscellaneous: In rat, the p62 complex contains two different isoforms of NUPL1. Isoform p45 has however not been
isolated in human so far
Sequence caution: Sequence=BAA23706.2; Type=Erroneous initiation;
Secondary accessions: A6NI12 B4DZJ1 O43160 Q5JRG2 Q5JRG5
Alternative splicing: 3 isoforms:  Q9BVL2-1   Q9BVL2-2   Q9BVL2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUPL1: NX_Q9BVL2

Explore proteomics data for NUPL1 at MOPED 

Post-translational modifications:

  • UniProtKB: O-glycosylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BVL2

  • NUPL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUPL1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001008564.1  NP_054808.1  

    ENSEMBL proteins: 
     ENSP00000371155   ENSP00000418341   ENSP00000418904   ENSP00000418244   ENSP00000418555  
     ENSP00000371137   ENSP00000371166   ENSP00000408147  
    Reactome Protein details: Q9BVL2
    Human Recombinant Protein Products for NUPL1: 
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    Cloud-Clone Corp. Proteins for NUPL1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope TAS--
    GO:0005643nuclear pore IEA--
    GO:0031965nuclear membrane IEA--

    NUPL1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR024882 Nucleoporin_p58/p45

    Graphical View of Domain Structure for InterPro Entry Q9BVL2

    ProtoNet protein and cluster: Q9BVL2

    UniProtKB/Swiss-Prot: NUPL1_HUMAN, Q9BVL2
    Domain: Contains FG repeats
    Similarity: Belongs to the NUPL1 family


    NUPL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUPL1_HUMAN, Q9BVL2
    Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear
    membrane (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005487nucleocytoplasmic transporter activity IEA--
    GO:0005515protein binding ----
         
    NUPL1 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for NUPL1:
     Decreased influenza A virus in  Nuclear 40S maturation defects  Nuclear 60S biogenesis defects  Nucleoplasmic pre-40S maturati 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NUPL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NUPL1

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    SwitchGear 3'UTR luciferase reporter plasmidNUPL1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUPL1 About   (see all 11)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Glucokinase by Glucokinase Regulatory Protein
    Rev-mediated nuclear export of HIV RNA0.94
    Hexose transport0.87
    Nuclear import of Rev protein0.94
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.82
    Interactions of Rev with host cellular proteins0.94
    Nuclear Pore Complex (NPC) Disassembly0.77
    Vpr-mediated nuclear import of PICs0.91
    Nuclear Envelope Breakdown0.77
    2HIV Life Cycle
    HIV Life Cycle0.92
    HIV Infection0.61
    Late Phase of HIV Life Cycle0.92
    Host Interactions of HIV factors0.60
    3Interferon Signaling
    Interferon Signaling0.61
    Antiviral mechanism by IFN-stimulated genes0.42
    Cytokine Signaling in Immune system0.61
    ISG15 antiviral mechanism0.42
    4M Phase
    M Phase0.88
    Mitotic M-M/G1 phases0.88
    5Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/29        Reactome Pathways for NUPL1 (see all 29)
        Antiviral mechanism by IFN-stimulated genes
    Late Phase of HIV Life Cycle
    Metabolism
    Cell Cycle
    M Phase


    1         Kegg Pathway  (Kegg details for NUPL1):
        RNA transport


    NUPL1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUPL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for NUPL1 (Q9BVL22, 3 ENSP000003711554) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK3P273612, 3, ENSP000002630254MINT-8260570 I2D: score=2 STRING: ENSP00000263025
    APCP250543, ENSP000002574304I2D: score=3 STRING: ENSP00000257430
    NUP62P371983, ENSP000003055034I2D: score=3 STRING: ENSP00000305503
    ABI3Q9P2A43I2D: score=1 
    NUP54ENSP000002648834STRING: ENSP00000264883
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006913nucleocytoplasmic transport ----
    GO:0007077mitotic nuclear envelope disassembly TAS--
    GO:0008645hexose transport TAS--

    NUPL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUPL1

    Search CenterWatch for drugs/clinical trials and news about NUPL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUPL1 gene (3 alternative transcripts): 
    NM_001008564.1  NM_014089.3  NM_001008565.1  

    Unigene Cluster for NUPL1:

    Nucleoporin like 1
    Hs.507537  [show with all ESTs]
    Unigene Representative Sequence: NM_014089
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381736(uc001uqi.3 uc001uqj.3) ENST00000481980 ENST00000480187
    ENST00000460326 ENST00000465068 ENST00000490231 ENST00000463407(uc001uqg.1)
    ENST00000466694 ENST00000381718 ENST00000495460 ENST00000381747 ENST00000394327
    ENST00000476553 ENST00000477876
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate NUPL1 (see all 40):
    hsa-miR-3651 hsa-miR-3142 hsa-miR-124 hsa-miR-330-3p hsa-miR-506 hsa-miR-324-5p hsa-miR-187* hsa-miR-3065-5p
    SwitchGear 3'UTR luciferase reporter plasmidNUPL1 3' UTR sequence
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    Additional mRNA sequence: 

    AF113020.1 AK025800.1 AK026604.1 AK123955.1 AK302946.1 AK303409.1 BC001104.2 CR749714.1 

    18 DOTS entries:

    DT.99940945  DT.445274  DT.91766461  DT.100752514  DT.211215  DT.92012394  DT.75194666  DT.424192 
    DT.75141615  DT.91766455  DT.92048228  DT.100729687  DT.120762740  DT.120762778  DT.75164528  DT.95102765 
    DT.97795218  DT.101963964 

    24/284 AceView cDNA sequences (see all 284):

    AI370657 CF146166 W40410 BU428822 AL700262 AA296216 AI631225 BM698449 
    AI753809 CD677679 BM469129 BU675746 BX641333 AI801165 AW518372 BM469727 
    AB007870 AW204373 BX115537 AI218033 AW504134 AA715045 BM455470 BI060187 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for NUPL1 (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^
    SP1:                          -     -           -           -     -                                                     -                                       
    SP2:                                                                                                                                                            
    SP3:        -     -     -     -     -           -           -     -                                                                                             
    SP4:                                                                                                                                                            
    SP5:                          -     -           -           -     -                 -                                                                           

    ExUns: 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20
    SP1:                                          
    SP2:        -                       -         
    SP3:                                          
    SP4:        -                                 
    SP5:                                          


    ECgene alternative splicing isoforms for NUPL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUPL1 expression in normal human tissues (normalized intensities)      NUPL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAAGTTAGG
    NUPL1 Expression
    About this image


    NUPL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             bone marrow cd34+   
     
     Bone (Muscoskeletal System)
             mandibular prominence tissue e10.0   
     
     Eye (Sensory Organs)
             retinal progenitor cell p0   
     
     Head Mesenchyme (Muscoskeletal System)
             mandibular prominence tissue e10.0   
     
     Neural Tube (Nervous System)
             Rhombencephalon

    See NUPL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUPL1

    SOURCE GeneReport for Unigene cluster: Hs.507537
        SABiosciences Custom PCR Arrays for NUPL1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUPL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NUPL1 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nupl11 , 5 nucleoporin like 11, 5 90.46(n)1
    92.67(a)1
      14 (31.62 cM)5
    718441  NM_170591.11  NP_733479.11 
     602194685 
    chicken
    (Gallus gallus)
    Aves NUPL11 nucleoporin like 1 83.14(n)
    88.61(a)
      418937  NM_001030829.1  NP_001026000.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUPL16
    Uncharacterized protein
    85(a)
    1 ↔ 1
    GL343306.1(84437-120020)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC041268.12   -- 76.58(n)    BC041268.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.44352 Transcribed sequence with moderate similarity to protein more 75.82(n)    BM101779.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nup581 Nucleoporin 58 43.36(n)
    33.26(a)
      42342  NM_142564.3  NP_650821.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NUP496
    Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcompl...
    4(a)
    1 ↔ 1
    VII(180700-182118)


    ENSEMBL Gene Tree for NUPL1 (if available)
    TreeFam Gene Tree for NUPL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUPL1 gene

    NUPL1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NUPL1
    PGOHUM00000245692


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/947 SNPs in NUPL1 are shown (see all 947)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0505704
    ----see VAR_0505702 A T mis40--------
    rs1117860571,2
    C,F--25873829(+) ATGACT/CTCTAT 2 -- us2k12Minor allele frequency- C:0.05CSA WA 120
    rs118412761,2
    C,F,H--25874004(+) gtggcG/Atgcgc 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1393970691,2
    C--25874008(+) CGTGCA/GCCTGT 2 -- us2k10--------
    rs1894687821,2
    --25874187(+) ACGTTC/TCTTTT 2 -- us2k10--------
    rs1456415141,2
    --25874266(+) GTGGCC/TATAAC 2 -- us2k10--------
    rs1820654681,2
    --25874297(+) AATTCG/TGGAGG 2 -- us2k10--------
    rs42381891,2
    C,F,A--25874436(+) atgggG/Cgaccc 2 -- us2k110Minor allele frequency- C:0.16NA WA CSA 253
    rs766541541,2
    C,F--25874518(+) GGGTAG/CGGCTT 2 -- us2k11Minor allele frequency- C:0.03WA 118
    rs47708181,2
    C,H--25874529(+) taacaT/Catgga 2 -- us2k1 tfbs34Minor allele frequency- C:0.00NS EA 420

    HapMap Linkage Disequilibrium report for NUPL1 (25875662 - 25923938 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NUPL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2747161CNV Deletion23290073
    dgv1566n71CNV Gain21882294
    nsv899943CNV Gain21882294
    nsv435952OTHER Inversion17901297

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607615    OMIM disorders: --

    2 diseases for NUPL1:    About MalaCards
    influenza    hepatitis


    NUPL1 for disorders           About GeneDecksing


    Export disorders for NUPL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUPL1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with NUPL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K....Ohara O. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    5. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9818 HGNC: 20261 AceView: NUPL1 Ensembl:ENSG00000139496 euGenes: HUgn9818
    ECgene: NUPL1 Kegg: 9818 H-InvDB: NUPL1

    (According to HUGE)
    About This Section
    HUGE: KIAA0410

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUPL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUPL1 gene:
    Search GeneIP for patents involving NUPL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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