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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUP93 Gene

protein-coding   GIFtS: 61
GCID: GC16P056764

Nucleoporin 93kDa

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleoporin 93kDa1 2
Nucleoporin Nup932 3
93 KDa Nucleoporin2 3
NIC962
Nuclear Pore Complex Protein Nup932
KIAA00953

External Ids:    HGNC: 289581   Entrez Gene: 96882   Ensembl: ENSG000001029007   OMIM: 6143515   UniProtKB: Q8N1F73   

Export aliases for NUP93 gene to outside databases

Previous GC identifers: GC16P056540 GC16P055322 GC16P042633


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NUP93 Gene: 
NUP93 (nucleoporin 93kDa) is a protein-coding gene. Diseases associated with NUP93 include myocardial infarction, and influenza, and among its related super-pathways are Interactions of Rev with host cellular proteins and HIV Life Cycle. GO annotations related to this gene include structural constituent of nuclear pore.

UniProtKB/Swiss-Prot: NUP93_HUMAN, Q8N1F7
Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but
not NUP153 and TPR, to the NPC

Gene Wiki entry for NUP93 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUP93 gene promoter:
         Sox5   p53   ATF-2   FOXO3   Lmo2   FOXO3b   CBF-A   FOXO3a   Hlf   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUP93 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUP93

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP93


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q13   HGNC cytogenetic band: 16q13

NUP93 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUP93 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056764:  view genomic region     (about GC identifiers)

Start:
56,764,017 bp from pter      End:
56,878,862 bp from pter
Size:
114,846 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUP93_HUMAN, Q8N1F7 (See protein sequence)
Recommended Name: Nuclear pore complex protein Nup93  
Size: 819 amino acids; 93488 Da
Subunit: Part of the nuclear pore complex (NPC). Component of the p62 complex, a complex composed of NUP62 and
NUP54. Forms a complex with NUP53, NUP155, NUP205 and lamin B; the interaction with NUP53 is direct. Does not
interact with TPR
Subcellular location: Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus
membrane; Peripheral membrane protein (By similarity). Note=Localizes at the nuclear basket and at or near the
nuclear entry to the gated channel of the pore
Sequence caution: Sequence=BAA07680.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B3KPQ8 Q14705
Alternative splicing: 2 isoforms:  Q8N1F7-1   Q8N1F7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUP93: NX_Q8N1F7

Explore proteomics data for NUP93 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N1F7

  • NUP93 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUP93 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001229724.1  NP_001229725.1  NP_055484.3  

    ENSEMBL proteins: 
     ENSP00000310668   ENSP00000455230   ENSP00000456264   ENSP00000458101   ENSP00000454587  
     ENSP00000457902   ENSP00000454285   ENSP00000454935   ENSP00000458039   ENSP00000455210  
     ENSP00000454844   ENSP00000455181   ENSP00000440235   ENSP00000458078   ENSP00000456196  
     ENSP00000457907  
    Reactome Protein details: Q8N1F7
    Human Recombinant Protein Products for NUP93: 
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    Novus Biologicals NUP93 Lysate
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    Cloud-Clone Corp. Proteins for NUP93 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope TAS--
    GO:0005643nuclear pore IDA12802065
    GO:0031965nuclear membrane IDA15229283
    GO:0034399nuclear periphery IDA15229283

    NUP93 for ontologies           About GeneDecksing



    NUP93 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007231 Nucleoporin_int_Nup93/Nic96

    Graphical View of Domain Structure for InterPro Entry Q8N1F7

    ProtoNet protein and cluster: Q8N1F7

    1 Blocks protein domain: IPB007231 Nucleoporin interacting component

    UniProtKB/Swiss-Prot: NUP93_HUMAN, Q8N1F7
    Similarity: Belongs to the nucleoporin interacting component (NIC) family


    NUP93 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUP93_HUMAN, Q8N1F7
    Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but
    not NUP153 and TPR, to the NPC

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017056structural constituent of nuclear pore IMP15229283
         
    NUP93 for ontologies           About GeneDecksing


    Phenotypes:
         7 GenomeRNAi human phenotypes for NUP93:
     Decreased viability  Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Nuclear 40S maturation defects 
     Nuclear 60S biogenesis defects  Nucleoplasmic pre-40S maturati  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NUP93 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NUP93

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NUP93 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NUP93 

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    hsa-mir-218 (MIRT001059)

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    hsa-miR-551b* hsa-miR-888*
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP93


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUP93 About   (see all 11)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Glucokinase by Glucokinase Regulatory Protein
    Rev-mediated nuclear export of HIV RNA0.94
    Hexose transport0.87
    Nuclear import of Rev protein0.94
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.82
    Interactions of Rev with host cellular proteins0.94
    Nuclear Pore Complex (NPC) Disassembly0.77
    Vpr-mediated nuclear import of PICs0.91
    Nuclear Envelope Breakdown0.77
    2HIV Life Cycle
    HIV Life Cycle0.92
    HIV Infection0.61
    Late Phase of HIV Life Cycle0.92
    Host Interactions of HIV factors0.60
    3Interferon Signaling
    Interferon Signaling0.61
    Antiviral mechanism by IFN-stimulated genes0.42
    Cytokine Signaling in Immune system0.61
    ISG15 antiviral mechanism0.42
    4M Phase
    M Phase0.88
    Mitotic M-M/G1 phases0.88
    5Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/29        Reactome Pathways for NUP93 (see all 29)
        Antiviral mechanism by IFN-stimulated genes
    Late Phase of HIV Life Cycle
    Metabolism
    Cell Cycle
    M Phase


    1         Kegg Pathway  (Kegg details for NUP93):
        RNA transport


    NUP93 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUP93

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/672 Interacting proteins for NUP93 (Q8N1F72, 3 ENSP000003106684) via UniProtKB, MINT, STRING, and/or I2D (see all 672)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AHCTF1Q8WYP52, 3, ENSP000003757054MINT-4301682 I2D: score=1 STRING: ENSP00000375705
    NUP155O756942, 3, ENSP000002314984MINT-7947479 I2D: score=1 STRING: ENSP00000231498
    RANGAP1P460602, 3MINT-7947479 I2D: score=1 
    SEH1LQ96EE32, 3MINT-7947479 I2D: score=1 
    XPO5Q9HAV42, 3MINT-7947479 I2D: score=1 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006810transport ----
    GO:0007077mitotic nuclear envelope disassembly TAS--
    GO:0008645hexose transport TAS--

    NUP93 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUP93

    Search CenterWatch for drugs/clinical trials and news about NUP93

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUP93 gene (3 alternative transcripts): 
    NM_001242795.1  NM_001242796.1  NM_014669.4  

    Unigene Cluster for NUP93:

    Nucleoporin 93kDa
    Hs.276878  [show with all ESTs]
    Unigene Representative Sequence: NM_001242795
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000308159(uc002eka.3) ENST00000563858 ENST00000566315 ENST00000569842
    ENST00000569863 ENST00000562496 ENST00000568656 ENST00000566678 ENST00000564887(uc002ekb.3)
    ENST00000569595 ENST00000566727 ENST00000567641 ENST00000568283 ENST00000567081
    ENST00000542526(uc010vhi.2) ENST00000563437 ENST00000563405 ENST00000563486

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NUP93:
    hsa-miR-551b* hsa-miR-888*
    SwitchGear 3'UTR luciferase reporter plasmidNUP93 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP93
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP93

    Additional mRNA sequence: 

    AF086282.1 AK056637.1 AK123594.1 AK125165.1 AK292262.1 AK294176.1 BC034346.1 D42085.1 

    24/32 DOTS entries (see all 32):

    DT.92455793  DT.100820791  DT.100820799  DT.446851  DT.95128057  DT.97855785  DT.102840071  DT.95128117 
    DT.120684870  DT.120685029  DT.100720893  DT.120684793  DT.101976608  DT.100820787  DT.120685027  DT.92455791 
    DT.100820789  DT.100773447  DT.100820783  DT.100820784  DT.120684751  DT.120684874  DT.120684895  DT.92455808 

    24/365 AceView cDNA sequences (see all 365):

    BM784365 AU132003 AU131463 D42085 AU131757 AA429171 BM708619 BQ420274 
    CB116124 BM757935 BU616997 CB216031 CD243223 BC034346 BU617675 BG194212 
    AI948881 CR624290 CA424108 CA424793 BM756864 BM757246 BM713897 CR612078 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for NUP93 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d · 11e ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^
    SP1:                          -     -           -                 -     -     -     -                                   -                                       
    SP2:                                                                    -     -     -                                   -                                       
    SP3:                                            -                 -     -     -     -                                   -                                       
    SP4:                          -     -           -           -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP5:                                -           -                 -     -     -     -                                                                           

    ExUns: 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26a · 26b · 26c ^ 27 ^ 28
    SP1:                                                                          -           -               
    SP2:                                                                          -           -               
    SP3:                                                                                                      
    SP4:  -                                                                                                   
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for NUP93

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUP93 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCCACTAG
    NUP93 Expression
    About this image


    See NUP93 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUP93

    SOURCE GeneReport for Unigene cluster: Hs.276878
        SABiosciences Custom PCR Arrays for NUP93
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP93

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NUP93 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nup931 , 5 nucleoporin 931, 5 89.78(n)1
    97.68(a)1
      8 (46.40 cM)5
    718051  NM_172410.21  NP_765998.11 
     942146015 
    chicken
    (Gallus gallus)
    Aves NUP931 nucleoporin 93kDa 80.42(n)
    92.06(a)
      415693  XM_001232546.2  XP_001232547.2 
    lizard
    (Anolis carolinensis)
    Reptilia NUP936
    Uncharacterized protein
    83(a)
    1 ↔ 1
    GL343675.1(209995-277084)
    African clawed frog
    (Xenopus laevis)
    Amphibia dye-prov2 hypothetical protein MGC53870 78.18(n)    U63919.1 
    zebrafish
    (Danio rerio)
    Actinopterygii dye2 dead eye 76.66(n)   30172  NM_130981.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG72621 CG7262 48.44(n)
    38.25(a)
      41804  NM_142147.3  NP_650404.1 
    worm
    (Caenorhabditis elegans)
    Secernentea npp-131 Protein NPP-13 42.2(n)
    28.62(a)
      171774  NM_170819.4  NP_740802.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NIC96(YFR002W)4
    NIC961
    Component of the nuclear pore complex, required for more4
    Nic96p1
    41.26(n)1
    28.67(a)1
      6(150016-152535)4
    8505521, 4  NP_116657.11, 4 


    ENSEMBL Gene Tree for NUP93 (if available)
    TreeFam Gene Tree for NUP93 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUP93 gene
    18/27 SIMAP similar genes for NUP93 using alignment to 14 protein entries:     NUP93_HUMAN (see all proteins) (see all similar genes):
    ADCK1    ARL6IP5    DYNC2LI1    VPS33A    PFKFB3    SEPSECS
    KIAA0101    ZNF799    C1orf143    CDK10    DPP9    COQ5
    ATF1    EEF1E1    NLRC5    ARIH1    ZNF114    RRM2B

    NUP93 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2292 SNPs in NUP93 are shown (see all 2292)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs116441591,2
    C,F,H--56766031(+) TTCACT/AAGGGA 1 -- int11Minor allele frequency- A:0.50NA 4
    rs1148180141,2
    F--56766057(+) TTTCCC/GCATTT 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1128310861,2
    F--56766058(+) TTCCCC/TATTTC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1451810671,2
    --56766066(+) TTCCCG/TCCTCC 1 -- int10--------
    rs1509551421,2
    --56766152(+) ATGTGA/GGTGAG 1 -- int10--------
    rs125995451,2
    H--56766202(+) acctaG/Tgtctg 1 -- int10--------
    rs1826855021,2
    C--56766343(+) GCAATA/GAAAGC 1 -- int10--------
    rs1394820701,2
    C--56766488(+) AAGACC/TGTGCA 1 -- int10--------
    rs1153722241,2
    F--56766493(+) CGTGCA/GGTGTG 1 -- int11Minor allele frequency- G:0.03WA 118
    rs1496611241,2
    C--56766534(+) CTGAAC/TCAGCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for NUP93 (56764017 - 56878862 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NUP93:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv833244CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614351    OMIM disorders: --

    3 diseases for NUP93:    About MalaCards
    myocardial infarction    influenza    hepatitis


    NUP93 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NUP93

    Export disorders for NUP93 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUP93 gene, integrated from 9 sources (see all 62):
    (articles sorted by number of sources associating them with NUP93)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly. (PubMed id 9348540)1, 2, 3, 9 Grandi P....Hurt E. (1997)
    2. Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. (PubMed id 15229283)1, 2, 9 Krull S....Cordes V.C. (2004)
    3. Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr. (PubMed id 9531546)1, 3, 9 Shah S....Forbes D. (1998)
    4. Polymorphism in the CETP gene region, HDL cholesterol , and risk of future myocardial infarction: Genomewide analysis among 18 245 in itially healthy women from the Women's Genome Health Study. (PubMed id 20031564)1, 4 Ridker P.M....Chasman D.I. (2009)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex. (PubMed id 12802065)1, 2 Hase M.E. and Cordes V.C. (2003)
    8. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2 Nagase T....Kotani H. (1995)
    9. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. (PubMed id 15703211)2, 9 Hawryluk-Gara L.A.... Wozniak R.W. (2005)
    10. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9688 HGNC: 28958 AceView: NUP93 Ensembl:ENSG00000102900 euGenes: HUgn9688
    ECgene: NUP93 Kegg: 9688 H-InvDB: NUP93

    (According to HUGE)
    About This Section
    HUGE: KIAA0095

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUP93 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUP93 gene:
    Search GeneIP for patents involving NUP93

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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