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Aliases for NUP62CL Gene

Aliases for NUP62CL Gene

  • Nucleoporin 62kDa C-Terminal Like 2 3
  • NUP62L 4

External Ids for NUP62CL Gene

Summaries for NUP62CL Gene

Entrez Gene Summary for NUP62CL Gene

  • This gene encodes a protein containing a domain found in nucleoporins which are glycoproteins found in nuclear pore complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

GeneCards Summary for NUP62CL Gene

NUP62CL (Nucleoporin 62kDa C-Terminal Like) is a Protein Coding gene. GO annotations related to this gene include structural constituent of nuclear pore. An important paralog of this gene is NUP62.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUP62CL Gene

Genomics for NUP62CL Gene

Genomic Location for NUP62CL Gene

Start:
107,123,427 bp from pter
End:
107,206,440 bp from pter
Size:
83,014 bases
Orientation:
Minus strand

Genomic View for NUP62CL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NUP62CL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUP62CL Gene

Regulatory Elements for NUP62CL Gene

Proteins for NUP62CL Gene

  • Protein details for NUP62CL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1M0-N62CL_HUMAN
    Recommended name:
    Nucleoporin-62 C-terminal-like protein
    Protein Accession:
    Q9H1M0
    Secondary Accessions:
    • D3DUX4
    • Q8WVL6
    • Q9NXP2

    Protein attributes for NUP62CL Gene

    Size:
    184 amino acids
    Molecular mass:
    20837 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NUP62CL Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NUP62CL Gene

Proteomics data for NUP62CL Gene at MOPED

Post-translational modifications for NUP62CL Gene

No Post-translational modifications

Other Protein References for NUP62CL Gene

No data available for DME Specific Peptides for NUP62CL Gene

Domains for NUP62CL Gene

Protein Domains for NUP62CL Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NUP62CL Gene

Graphical View of Domain Structure for InterPro Entry

Q9H1M0

UniProtKB/Swiss-Prot:

N62CL_HUMAN
Family:
  • Belongs to the nucleoporin NSP1/NUP62 family.:
    • Q9H1M0
genes like me logo Genes that share domains with NUP62CL: view

No data available for Gene Families for NUP62CL Gene

Function for NUP62CL Gene

Gene Ontology (GO) - Molecular Function for NUP62CL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
GO:0017056 structural constituent of nuclear pore IEA --
genes like me logo Genes that share ontologies with NUP62CL: view

miRNA for NUP62CL Gene

miRTarBase miRNAs that target NUP62CL

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for NUP62CL Gene

Localization for NUP62CL Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NUP62CL Gene COMPARTMENTS Subcellular localization image for NUP62CL gene
Compartment Confidence
cytosol 3
mitochondrion 3
nucleus 2
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for NUP62CL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005643 nuclear pore IEA --
genes like me logo Genes that share ontologies with NUP62CL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for NUP62CL Gene

Pathways for NUP62CL Gene

SuperPathways for NUP62CL Gene

No Data Available

Gene Ontology (GO) - Biological Process for NUP62CL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with NUP62CL: view

No data available for Pathways by source for NUP62CL Gene

Transcripts for NUP62CL Gene

mRNA/cDNA for NUP62CL Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(20) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for NUP62CL Gene

Nucleoporin 62kDa C-terminal like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NUP62CL Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP1:
SP2: - -

Relevant External Links for NUP62CL Gene

GeneLoc Exon Structure for
NUP62CL
ECgene alternative splicing isoforms for
NUP62CL

Expression for NUP62CL Gene

mRNA expression in normal human tissues for NUP62CL Gene

mRNA differential expression in normal tissues according to GTEx for NUP62CL Gene

This gene is overexpressed in Testis (7.8) and Adrenal Gland (4.5).

SOURCE GeneReport for Unigene cluster for NUP62CL Gene Hs.163629

genes like me logo Genes that share expressions with NUP62CL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for NUP62CL Gene

Orthologs for NUP62CL Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NUP62CL Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NUP62CL 35
  • 99.28 (n)
  • 98.91 (a)
NUP62CL 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NUP62CL 36
  • 21 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nup62cl 16
Nup62cl 36
  • 30 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 12 (a)
ManyToMany
-- 36
  • 15 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 19 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 19 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 16 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii nup62l 36
  • 18 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Nup62 36
  • 15 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NSP1 36
  • 2 (a)
ManyToMany
NUP1 36
  • 1 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 18 (a)
OneToMany
Species with no ortholog for NUP62CL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NUP62CL Gene

ENSEMBL:
Gene Tree for NUP62CL (if available)
TreeFam:
Gene Tree for NUP62CL (if available)

Paralogs for NUP62CL Gene

Paralogs for NUP62CL Gene

Selected SIMAP similar genes for NUP62CL Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with NUP62CL: view

Variants for NUP62CL Gene

Sequence variations from dbSNP and Humsavar for NUP62CL Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs967194 -- 107,131,340(-) TCTCA(G/T)CAAAA intron-variant
rs970030 -- 107,143,757(+) ATAAC(A/G)ATTAT intron-variant
rs982835 -- 107,154,804(+) CAGCA(C/G)GGCTC intron-variant
rs1116288 -- 107,178,625(-) TAATA(A/G)GAGCA intron-variant
rs1285546 -- 107,130,202(-) TGTTT(C/G)ACCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NUP62CL Gene

Variant ID Type Subtype PubMed ID
esv2752312 CNV Gain 17911159
nsv519484 CNV Gain 19592680
esv2740376 CNV Deletion 23290073
nsv7027 CNV Insertion 18451855
esv1568973 CNV Insertion 17803354

Relevant External Links for NUP62CL Gene

HapMap Linkage Disequilibrium report
NUP62CL
Locus Specific Mutation Databases (LSDB)
NUP62CL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUP62CL Gene

Disorders for NUP62CL Gene

No disorders were found for NUP62CL Gene.

No data available for UniProtKB/Swiss-Prot for NUP62CL Gene

Publications for NUP62CL Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for NUP62CL Gene

Sources for NUP62CL Gene

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