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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUP54 Gene

protein-coding   GIFtS: 56
GCID: GC04M077035

Nucleoporin 54kDa

(Previous name: nucleoporin 54kD)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleoporin 54kDa1 2
54 KDa Nucleoporin2 3
Nucleoporin 54kD1
Nucleoporin P542

External Ids:    HGNC: 173591   Entrez Gene: 533712   Ensembl: ENSG000001387507   OMIM: 6076075   UniProtKB: Q7Z3B43   

Export aliases for NUP54 gene to outside databases

Previous GC identifers: GC04M076931 GC04M077225 GC04M077428 GC04M077494 GC04M077392 GC04M072788


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUP54 Gene:
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two
concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate
the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100
different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the
phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been
found for this gene. (provided by RefSeq, Jun 2013)

GeneCards Summary for NUP54 Gene: 
NUP54 (nucleoporin 54kDa) is a protein-coding gene. Diseases associated with NUP54 include renal cell carcinoma, and influenza, and among its related super-pathways are Interactions of Rev with host cellular proteins and HIV Life Cycle. GO annotations related to this gene include nucleocytoplasmic transporter activity.

UniProtKB/Swiss-Prot: NUP54_HUMAN, Q7Z3B4
Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear
membrane (By similarity)

Gene Wiki entry for NUP54 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUP54 gene promoter:
         E2F-4   E2F-3a   E2F-5   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   E2F-2   Ik-3   POU3F2   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUP54 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUP54

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP54


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21.1

NUP54 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUP54 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M077035:  view genomic region     (about GC identifiers)

Start:
77,035,812 bp from pter      End:
77,069,668 bp from pter
Size:
33,857 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUP54_HUMAN, Q7Z3B4 (See protein sequence)
Recommended Name: Nucleoporin p54  
Size: 507 amino acids; 55435 Da
Subunit: Component of the p62 complex, a complex composed of NUP62, NUP54, and the isoform p58 and isoform p45 of
NUPL1 (By similarity)
Subcellular location: Nucleus, nuclear pore complex (By similarity). Nucleus membrane; Peripheral membrane
protein; Cytoplasmic side (By similarity). Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By
similarity). Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the
transporter (By similarity)
Sequence caution: Sequence=BAA91735.1; Type=Frameshift; Positions=479;
Secondary accessions: B2RCK7 Q96EA7 Q9NVL5 Q9P0I1
Alternative splicing: 2 isoforms:  Q7Z3B4-1   Q7Z3B4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUP54: NX_Q7Z3B4

Explore proteomics data for NUP54 at MOPED 

Post-translational modifications:

  • UniProtKB: O-glycosylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z3B4

  • NUP54 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUP54 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001265532.1  NP_059122.2  

    ENSEMBL proteins: 
     ENSP00000425243   ENSP00000264883   ENSP00000426609   ENSP00000421304   ENSP00000424172  
     ENSP00000421932   ENSP00000424389   ENSP00000344052   ENSP00000406103  
    Reactome Protein details: Q7Z3B4
    Human Recombinant Protein Products for NUP54: 
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    Cloud-Clone Corp. Proteins for NUP54 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope TAS--
    GO:0005643nuclear pore IEA--
    GO:0005654nucleoplasm TAS8707840
    GO:0005737cytoplasm TAS8707840
    GO:0031965nuclear membrane IEA--

    NUP54 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR024864 Nup54/Nup57/Nup44
     IPR025712 Nup54_alpha-helical_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z3B4

    ProtoNet protein and cluster: Q7Z3B4

    UniProtKB/Swiss-Prot: NUP54_HUMAN, Q7Z3B4
    Domain: Contains FG repeats
    Similarity: Belongs to the NUP54 family


    NUP54 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUP54_HUMAN, Q7Z3B4
    Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear
    membrane (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005487nucleocytoplasmic transporter activity IEA--
    GO:0005515protein binding ----
         
    NUP54 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for NUP54:
     Decreased Wnt reporter activit  Nuclear 60S biogenesis defects  Nucleoplasmic pre-40S maturati 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NUP54 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUP54 About   (see all 11)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Glucokinase by Glucokinase Regulatory Protein
    Rev-mediated nuclear export of HIV RNA0.94
    Hexose transport0.87
    Nuclear import of Rev protein0.94
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.82
    Interactions of Rev with host cellular proteins0.94
    Nuclear Pore Complex (NPC) Disassembly0.77
    Vpr-mediated nuclear import of PICs0.91
    Nuclear Envelope Breakdown0.77
    2HIV Life Cycle
    HIV Life Cycle0.92
    HIV Infection0.61
    Late Phase of HIV Life Cycle0.92
    Host Interactions of HIV factors0.60
    3Interferon Signaling
    Interferon Signaling0.61
    Antiviral mechanism by IFN-stimulated genes0.42
    Cytokine Signaling in Immune system0.61
    ISG15 antiviral mechanism0.42
    4M Phase
    M Phase0.88
    Mitotic M-M/G1 phases0.88
    5Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/29        Reactome Pathways for NUP54 (see all 29)
        Antiviral mechanism by IFN-stimulated genes
    Late Phase of HIV Life Cycle
    Metabolism
    Cell Cycle
    M Phase


    1         Kegg Pathway  (Kegg details for NUP54):
        RNA transport


    NUP54 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUP54

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/85 Interacting proteins for NUP54 (Q7Z3B42, 3 ENSP000002648834) via UniProtKB, MINT, STRING, and/or I2D (see all 85)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-68368 I2D: score=5 STRING: ENSP00000311695
    NUP62P371982, 3, ENSP000003055034MINT-66139 I2D: score=6 STRING: ENSP00000305503
    AP2B1P630102, 3, ENSP000003144144MINT-67650 I2D: score=5 STRING: ENSP00000314414
    APCP250543, ENSP000002574304I2D: score=3 STRING: ENSP00000257430
    NUTF2P619703, ENSP000002191694I2D: score=2 STRING: ENSP00000219169
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006605protein targeting IEA--
    GO:0006913nucleocytoplasmic transport ----
    GO:0007077mitotic nuclear envelope disassembly TAS--

    NUP54 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUP54

    Search CenterWatch for drugs/clinical trials and news about NUP54

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUP54 gene (2 alternative transcripts): 
    NM_001278603.1  NM_017426.3  

    Unigene Cluster for NUP54:

    Nucleoporin 54kDa
    Hs.430435  [show with all ESTs]
    Unigene Representative Sequence: NM_017426
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000508604 ENST00000507257 ENST00000264883(uc003hjs.3 uc010ije.3 uc011cbs.2 uc011cbt.2 uc003hjt.3)
    ENST00000502850 ENST00000508465 ENST00000514987 ENST00000512151 ENST00000513248
    ENST00000504173 ENST00000514313 ENST00000515460 ENST00000514307 ENST00000506098
    ENST00000514901 ENST00000508583 ENST00000510569 ENST00000510884 ENST00000513352

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NUP54:
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    Additional mRNA sequence: 

    AF157322.1 AK001517.1 AK222752.1 AK223352.1 AK299442.1 AK300036.1 AK307571.1 AK315160.1 
    BC012559.1 BC034226.1 BX538002.1 

    17 DOTS entries:

    DT.414013  DT.95077094  DT.436689  DT.92433214  DT.121217906  DT.40232664  DT.121217926  DT.121217887 
    DT.97814143  DT.100023436  DT.100779541  DT.101954398  DT.102824279  DT.101966177  DT.121217907  DT.121217920 
    DT.95358579 

    24/184 AceView cDNA sequences (see all 184):

    BG548343 BI518687 BE551760 BU160859 BM457215 BM667524 BP371261 AL558709 
    AA782770 BU682623 BX091745 AA291034 BP376671 CN480564 N20965 AI623874 
    CB129366 AL513646 NM_017426 AL704512 AU129632 AA736499 AU279848 BE897592 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for NUP54 (see all 16)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b ^
    SP1:                          -     -     -                                                                       -                       -                     
    SP2:                                                              -     -     -                                   -                 -     -                     
    SP3:                          -     -     -                       -     -     -                                                                                 
    SP4:                          -     -     -                       -     -     -                             -     -                                             
    SP5:                                                                                                                                      -           -         

    ExUns: 14a · 14b · 14c · 14d
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for NUP54

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUP54 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGGAAAAA
    NUP54 Expression
    About this image


    See NUP54 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUP54

    SOURCE GeneReport for Unigene cluster: Hs.430435
        SABiosciences Custom PCR Arrays for NUP54
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NUP54 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nup541 , 5 nucleoporin 541, 5 87.97(n)1
    96.06(a)1
      5 (46.75 cM)5
    2691131  NM_183392.21  NP_899248.11 
     924155405 
    chicken
    (Gallus gallus)
    Aves NUP541 nucleoporin 54kDa 80.07(n)
    89.2(a)
      422639  XM_420594.3  XP_420594.2 
    lizard
    (Anolis carolinensis)
    Reptilia NUP546
    Uncharacterized protein
    85(a)
    1 ↔ 1
    5(146919438-146928162)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685412 hypothetical protein MGC68541 76.09(n)    BC060003.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufp63g062 wufp63g06 74.06(n)   335750  57041402 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG88313
    Nup541
    Nucleoporin 541 39(a)3
    49.89(n)1
    43.23(a)1
      49A43
    363601  NM_136939.31  NP_610783.11 
    worm
    (Caenorhabditis elegans)
    Secernentea npp-11 Protein NPP-1 46.29(n)
    29.95(a)
      177836  NM_069369.2  NP_501770.1 


    ENSEMBL Gene Tree for NUP54 (if available)
    TreeFam Gene Tree for NUP54 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUP54 gene
    1 SIMAP similar gene for NUP54 using alignment to 7 protein entries:     NUP54_HUMAN (see all proteins):
    DKFZp434L1613

    NUP54 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/895 SNPs in NUP54 are shown (see all 895)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs716593091,2
    C--76872883(+) ATTTGT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs588222351,2
    C--76889977(+) TAAGAA/GGCAGT 1 -- us2k14Minor allele frequency- G:0.21NA WA EA 360
    rs606716511,2
    C--76890011(+) GACCTC/AGTGCA 1 -- us2k14Minor allele frequency- A:0.21NA WA EA 360
    rs755990061,2
    C--77035332(+) ACTCC-/AGAT  
            
    AGATA
    1 -- ds50010--------
    rs2007609041,2
    C--77035335(+) CCAGAC/TAGATA 1 -- ds50010--------
    rs2021102311,2
    C--77035356(+) CACAC-/TCTTCACC 1 -- ds50010--------
    rs1131963591,2
    C,F--77035383(+) TACAAC/TAGCAA 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1156723041,2
    --77035423(+) GTCAAC/TACAAG 1 -- ds50010--------
    rs790325641,2
    C--77035447(+) GAGAA-/GTGCAA 1 -- ds50010--------
    rs777974931,2
    C--77035493(+) CCCAA-/AT/TA 
            
    ATATA
    1 -- ds50010--------

    HapMap Linkage Disequilibrium report for NUP54 (77035812 - 77069668 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NUP54:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv470047CNV Gain18288195
    nsv461558CNV Gain19166990
    esv275315CNV Gain+Loss21479260
    nsv7363OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607607    OMIM disorders: --

    3 diseases for NUP54:    About MalaCards
    renal cell carcinoma    influenza    hepatitis


    NUP54 for disorders           About GeneDecksing


    Export disorders for NUP54 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUP54 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with NUP54)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    3. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. (PubMed id 8707840)1, 3 Hu T....Gerace L. (1996)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53371 HGNC: 17359 AceView: NUP54 Ensembl:ENSG00000138750 euGenes: HUgn53371
    ECgene: NUP54 Kegg: 53371 H-InvDB: NUP54

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUP54 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUP54 gene:
    Search GeneIP for patents involving NUP54

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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