External Ids for NUP54 Gene
Previous GeneCards Identifiers for NUP54 Gene
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
GeneCards Summary for NUP54 Gene
NUP54 (Nucleoporin 54kDa) is a Protein Coding gene. Among its related pathways are Cellular response to heat stress and Glycosaminoglycan metabolism. GO annotations related to this gene include nucleocytoplasmic transporter activity.
UniProtKB/Swiss-Prot for NUP54 Gene
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.