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Aliases for NUP210L Gene

Aliases for NUP210L Gene

  • Nucleoporin 210kDa-Like 2 3
  • Nucleoporin 210 KDa-Like 4
  • Nucleoporin Nup210-Like 4

External Ids for NUP210L Gene

Previous GeneCards Identifiers for NUP210L Gene

  • GC01M150780
  • GC01M152231
  • GC01M153965
  • GC01M125327

Summaries for NUP210L Gene

GeneCards Summary for NUP210L Gene

NUP210L (Nucleoporin 210kDa-Like) is a Protein Coding gene. Among its related pathways are RNA transport. An important paralog of this gene is NUP210.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUP210L Gene

Genomics for NUP210L Gene

Regulatory Elements for NUP210L Gene

Genomic Location for NUP210L Gene

Start:
153,992,685 bp from pter
End:
154,155,116 bp from pter
Size:
162,432 bases
Orientation:
Minus strand

Genomic View for NUP210L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NUP210L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUP210L Gene

Proteins for NUP210L Gene

  • Protein details for NUP210L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VU65-P210L_HUMAN
    Recommended name:
    Nuclear pore membrane glycoprotein 210-like
    Protein Accession:
    Q5VU65
    Secondary Accessions:
    • E7EP56
    • Q5T4L7
    • Q6ZRN1
    • Q6ZRT4
    • Q6ZU81
    • Q8NDI6
    • Q9UF31

    Protein attributes for NUP210L Gene

    Size:
    1888 amino acids
    Molecular mass:
    210605 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86345.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC87279.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAB63757.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for NUP210L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NUP210L Gene

Proteomics data for NUP210L Gene at MOPED

Post-translational modifications for NUP210L Gene

  • Glycosylation at Asn84, Asn304, Asn348, Asn495, Asn522, Asn812, Asn931, Asn1445, and Asn1859
  • Modification sites at PhosphoSitePlus

Other Protein References for NUP210L Gene

No data available for DME Specific Peptides for NUP210L Gene

Domains for NUP210L Gene

Protein Domains for NUP210L Gene

Suggested Antigen Peptide Sequences for NUP210L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VU65

UniProtKB/Swiss-Prot:

P210L_HUMAN :
  • Q5VU65
Family:
  • Belongs to the NUP210 family.
genes like me logo Genes that share domains with NUP210L: view

No data available for Gene Families for NUP210L Gene

Function for NUP210L Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NUP210L

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NUP210L Gene

Localization for NUP210L Gene

Subcellular locations from UniProtKB/Swiss-Prot for NUP210L Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NUP210L Gene COMPARTMENTS Subcellular localization image for NUP210L gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
extracellular 1
lysosome 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for NUP210L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NUP210L: view

Pathways for NUP210L Gene

SuperPathways for NUP210L Gene

Superpath Contained pathways
1 RNA transport
genes like me logo Genes that share pathways with NUP210L: view

Pathways by source for NUP210L Gene

1 KEGG pathway for NUP210L Gene

Interacting Proteins for NUP210L Gene

Gene Ontology (GO) - Biological Process for NUP210L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007286 spermatid development IEA --
GO:0060009 Sertoli cell development IEA --
genes like me logo Genes that share ontologies with NUP210L: view

Transcripts for NUP210L Gene

Unigene Clusters for NUP210L Gene

Nucleoporin 210kDa-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NUP210L

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUP210L Gene

No ASD Table

Relevant External Links for NUP210L Gene

GeneLoc Exon Structure for
NUP210L
ECgene alternative splicing isoforms for
NUP210L

Expression for NUP210L Gene

mRNA expression in normal human tissues for NUP210L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NUP210L Gene

This gene is overexpressed in Testis (37.6).

Protein differential expression in normal tissues for NUP210L Gene

This gene is overexpressed in Ovary (40.4) and Testis (23.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for NUP210L Gene

SOURCE GeneReport for Unigene cluster for NUP210L Gene Hs.67639

genes like me logo Genes that share expressions with NUP210L: view

Expression partners for NUP210L Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for NUP210L Gene

Orthologs for NUP210L Gene

This gene was present in the common ancestor of animals.

Orthologs for NUP210L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NUP210L 35
  • 89.86 (n)
  • 89.47 (a)
NUP210L 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NUP210L 35
  • 89.35 (n)
  • 88.51 (a)
NUP210L 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nup210l 35
  • 83.43 (n)
  • 83.43 (a)
Nup210l 16
Nup210l 36
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia NUP210L 35
  • 99.61 (n)
  • 99.36 (a)
NUP210L 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nup210l 35
  • 83.07 (n)
  • 82.84 (a)
oppossum
(Monodelphis domestica)
Mammalia NUP210L 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 31 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 70 (a)
OneToMany
chicken
(Gallus gallus)
Aves NUP210L 35
  • 64.47 (n)
  • 58.92 (a)
NUP210L 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NUP210L 36
  • 60 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta gp210 36
  • 21 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea npp-12 36
  • 19 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToMany
Species with no ortholog for NUP210L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for NUP210L Gene

ENSEMBL:
Gene Tree for NUP210L (if available)
TreeFam:
Gene Tree for NUP210L (if available)

Paralogs for NUP210L Gene

Paralogs for NUP210L Gene

Selected SIMAP similar genes for NUP210L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NUP210L: view

Variants for NUP210L Gene

Sequence variations from dbSNP and Humsavar for NUP210L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs10797030 -- 154,103,458(+) ACGAG(C/G)TCAGG intron-variant
rs10796986 -- 154,014,936(+) AAGGT(A/G)GAGGT intron-variant
rs10573016 -- 154,122,230(+) ACATG(-/TG)AATGG intron-variant
rs10531787 -- 154,127,554(+) GGTTC(-/TT)TTTTT intron-variant
rs10159084 -- 154,084,214(+) tttaa(A/T)ttttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NUP210L Gene

Variant ID Type Subtype PubMed ID
esv2718306 CNV Deletion 23290073
nsv520398 CNV Gain+Loss 19592680
esv2586978 CNV Deletion 19546169
esv2063006 CNV Deletion 18987734
esv2660112 CNV Deletion 23128226
esv2648729 CNV Loss 19546169
nsv872451 CNV Gain 21882294
esv274351 CNV Insertion 20981092
esv267891 CNV Insertion 20981092

Relevant External Links for NUP210L Gene

HapMap Linkage Disequilibrium report
NUP210L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUP210L Gene

Disorders for NUP210L Gene

No disorders were found for NUP210L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NUP210L Gene

Publications for NUP210L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PMID: 22053931) Oshikawa K. … Nakayama K.I. (J. Proteome Res. 2012) 3
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for NUP210L Gene

Sources for NUP210L Gene

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