NUP210L Gene
protein-coding GIFtS: 41
GCID: GC01M153965
|
|
nucleoporin 210kDa-like
| |
Aliases
for NUP210L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nucleoporin 210kDa-Like1 2 | | Nucleoporin Nup210-Like2 3 | | RP11-144B19.12 | | Nuclear Pore Membrane Glycoprotein 210-Like2 | | Nuclear Pore Membrane Glycoprotein 210-Like (LOC91181)2 | | Nucleoporin 210 KDa-Like3 |
Export aliases for NUP210L gene to outside databasesPrevious GC identifers: GC01M150780 GC01M152231 GC01M125327 |
Summaries
for NUP210L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for NUP210L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NUP210L gene promoter:
AhR SRF AML1a SRF (504 AA) CUTL1 GATA-1 Arnt POU2F1 POU2F1a ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUP210L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP210L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.3NUP210L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M153965: view genomic region
(about GC identifiers)
Start:
|
153,965,161 bp from pter |
End:
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154,127,592 bp from pter |
Size:
|
162,432 bases |
Orientation:
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minus strand |
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Proteins
for NUP210L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: P210L_HUMAN, Q5VU65 (See
protein sequence)Recommended Name: Nuclear pore membrane glycoprotein 210-like precursor Size: 1888 amino acids; 210605 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Sequence caution: Sequence=BAC86345.1; Type=Erroneous initiation; Sequence=BAC87279.1; Type=Erroneous initiation;
Secondary accessions: Q5T4L7 Q6ZRN1 Q6ZRT4 Q6ZU81 Q8NDI6Explore the universe of human proteins at neXtProt for NUP210L: NX_Q5VU65
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5VU65
NUP210L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001152956.1 NP_997191.2
ENSEMBL proteins: ENSP00000357547 ENSP00000357541 ENSP00000271854
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
NUP210L for ontologies About GeneDecksing
NUP210L Antibody Products:
Assay Products for NUP210L: |
Protein
Domains /
Families
for NUP210L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUP210L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5VU65ProtoNet protein and cluster: Q5VU65 1 Blocks protein family: IPB003343 Bacterial Ig-like
UniProtKB/Swiss-Prot: P210L_HUMAN, Q5VU65Similarity: Belongs to the NUP210 family |
Function
for NUP210L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP210L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP210L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for NUP210L | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUP210L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP210L |
|
Pathways & Interactions
for NUP210L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for NUP210L):
NUP210L for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUP210L
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for NUP210L (ENSP000003575474) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for NUP210L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NUP210L
Search CenterWatch for drugs/clinical trials and news about NUP210L / P210L
|
Transcripts
for NUP210L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NUP210L gene (2 alternative transcripts): NM_001159484.1 NM_207308.2 Unigene Cluster for NUP210L: Nucleoporin 210kDa-like Hs.67639 [show with all ESTs]Unigene Representative Sequence: NM_2073083 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000368559(uc009woq.3 uc001fdw.3 uc010peh.2) ENST00000368553
ENST00000271854
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP210L (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP210L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NUP210L (NM_207308) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUP210L | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUP210L |
Additional cDNA sequence: AK125924.1 AK128000.1 AK128108.1 AL133633.1 AL833964.1 BX648132.1 3 DOTS entries: DT.206359 DT.101981855 DT.95079270 24/1845 AceView cDNA sequences (see all 1845): BU178578 BQ061819 BU192291 CR597930 BI859759 BG741800 BQ218630 CB529019 BU735976 AF474157 BE791924 H63322 CB143169 AI953904 BU616389 BQ689793 BQ069508 BQ932473 BQ936845 AW511609 BM835944 AA906955 BQ641304 BQ876654
GeneLoc Exon Structure
|
Expression
for NUP210L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NUP210L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NUP210L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUP210L
SOURCE GeneReport for Unigene cluster: Hs.67639
SABiosciences Custom PCR Arrays for NUP210L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUP210L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NUP210L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUP210L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP210L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP210L |
Orthologs
for NUP210L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NUP210L gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NUP210L1 |
nucleoporin 210kDa-like |
64.27(n)
58.92(a) |
|
426146 XM_001233383.1 XP_001233384.1 |
lizard
(Anolis carolinensis) |
Reptilia |
NUP210L6 |
-- |
60(a) |
1 ↔ 1 |
GL343805.1(57187-100770) |
fruit fly
(Drosophila melanogaster) |
Insecta |
gp2106 |
gp210 |
20(a) |
1 → many |
2R(1648373-1660077) |
worm
(Caenorhabditis elegans) |
Secernentea |
npp-126 |
Nuclear Pore complex Protein family member (npp-12... |
23(a) |
1 → many |
I(6447311-6453951) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
EMB30126 |
protein embryo defective 3012 |
18(a) |
1 → many |
5(16213222-16224058) |
rice
(Oryza sativa) |
Liliopsida |
-- |
nuclear pore protein-like, putative, expressed |
17(a) |
1 → many |
9(22526772-22535091) |
ENSEMBL Gene Tree for NUP210L (if available)
TreeFam Gene Tree for NUP210L (if available) |
Paralogs
for NUP210L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NUP210L gene
- NUP2102
2 SIMAP similar genes for NUP210L using alignment to 2 protein entries: P210L_HUMAN (see all proteins):DKFZp434E2118 NUP210
NUP210L for paralogs About GeneDecksing
|
Genomic Variants
for NUP210L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NUP210L (153965161 - 154127592 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NUP210L
2 CNVs: 43741 97515 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUP210L |
|
Disorders
/ Diseases
for NUP210L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for NUP210L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUP210L gene integrated from 9 sources:
(articles sorted by number of sources associating them with NUP210L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
|
External Searches for NUP210L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NUP210L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUP210L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUP210L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NUP210L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NUP210L gene:
Search GeneIP for patents involving NUP210L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NUP210L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |
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| |  |  |  |  | | | | |
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 | | | NUP210L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP210L |
|  |  |  | | | | Search ThermoFisher Antibodies for NUP210L |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUP210L |
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