External Ids for NUP188 Gene
Previous HGNC Symbols for NUP188 Gene
Previous GeneCards Identifiers for NUP188 Gene
The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013]
GeneCards Summary for NUP188 Gene
NUP188 (Nucleoporin 188kDa) is a Protein Coding gene. Among its related pathways are Cellular response to heat stress and Glycosaminoglycan metabolism. GO annotations related to this gene include binding. An important paralog of this gene is ENSG00000251184.
UniProtKB/Swiss-Prot for NUP188 Gene
May function as a component of the nuclear pore complex (NPC).