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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NUP160 Gene

protein-coding GIFtS: 57
GCID: GC11M048084

nucleoporin 160kDa

(Previous name: nucleoporin 160kD )

Explore 2 diseases affiliated with
NUP160 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Nucleoporin 160kDa¹ ²		FLJ22583¹
KIAA0197¹ ³ ⁵		Nucleoporin 160kD¹
Nucleoporin Nup160² ³		Nuclear Pore Complex Protein Nup160²
160 KDa Nucleoporin² ³		NUP120³

External Ids:	HGNC: 18017¹	Entrez Gene: 23279²	Ensembl: ENSG00000030066⁷	OMIM: 607614⁵	UniProtKB: Q12769³

Export aliases for NUP160 gene to outside databases

Previous GC identifers: GC11M049712 GC11M048677 GC11M047831 GC11M047763 GC11M047757 GC11M047505 GC11M047866

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUP160:

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic

transport.(supplied by OMIM, Apr 2004)

UniProtKB/Swiss-Prot: NU160_HUMAN, Q12769

Function: Involved in poly(A)+ RNA transport

Gene Wiki entry for NUP160

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NUP160 gene promoter:
STAT1 USF1 Egr-1 STAT1beta C/EBPalpha POU2F1 POU2F1a USF-1 STAT2 STAT3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NUP160 promoter sequence

Search SABiosciences Chromatin IP Primers for NUP160

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP160

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.12

NUP160 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUP160 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M048084: view genomic region (about GC identifiers)

Start:	47,799,639 bp from pter	End:	47,870,107 bp from pter
Size:	70,469 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NU160_HUMAN, Q12769 (See protein sequence)

Recommended Name: Nuclear pore complex protein Nup160

Size: 1436 amino acids; 162121 Da

Subunit: Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96.

This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus

Subcellular location: Nucleus, nuclear pore complex

Caution: It is uncertain whether Met-1 or Met-35 is the initiator

Sequence caution: Sequence=AAH09822.1; Type=Erroneous initiation; Sequence=BAA12110.1; Type=Miscellaneous discrepancy;

Note=Probable cloning artifact. Aberrant splice sites; Sequence=BAB15406.1; Type=Erroneous initiation;

Sequence=BAG65161.1; Type=Erroneous initiation;

Secondary accessions: B4DYE8 B4E2J9 Q08AD3 Q7Z5X6 Q96GB3 Q9H660

Alternative splicing: 3 isoforms: Q12769-1 Q12769-2 Q12769-3

Explore the universe of human proteins at neXtProt for NUP160: NX_Q12769

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q12769

NUP160 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_056046.1

ENSEMBL proteins:

ENSP00000367721 ENSP00000433590 ENSP00000432367 ENSP00000433964 ENSP00000432437

ENSP00000431495

Reactome Protein details: Q12769
Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
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	Novus Biologicals NUP160 Protein Novus Biologicals NUP160 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NUP160

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000776	colocalizes with kinetochore	IDA	15146057
GO:0005635	nuclear envelope	TAS	--
GO:0005643	nuclear pore	IDA	17098863
GO:0005829	cytosol	TAS	--
GO:0031080	nuclear pore outer ring	NAS	15146057

NUP160 for ontologies About GeneDecksing

NUP160 Antibody Products:

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	Uscn ELISAs and CLIAs for NUP160

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NUP160 for domains About GeneDecksing

1 InterPro domain/family:

IPR021717 Nucleoporin_Nup160

Graphical View of Domain Structure for InterPro Entry Q12769

ProtoNet protein and cluster: Q12769

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NU160_HUMAN, Q12769

Function: Involved in poly(A)+ RNA transport

miRNA Products:		OriGene 3'-UTR Clone: NUP160 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUP160
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate NUP160 (see all 18):
		hsa-miR-1226 hsa-miR-300 hsa-miR-520d-5p hsa-miR-29a hsa-miR-29c hsa-miR-223 hsa-miR-133a hsa-miR-889

		SwitchGear 3'UTR luciferase reporter plasmid: NUP160 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUP160 (see all 6) OriGene siRNA: NUP160
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUP160

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for NUP160

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP160 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP160 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NUP160 (NM_015231)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUP160
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP160

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NUP160
		Search LifeMap BioReagents cell lines for NUP160

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP160

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005487	nucleocytoplasmic transporter activity	IDA	11684705
GO:0005515	protein binding	IPI	15146057

NUP160 for ontologies About GeneDecksing

6 GenomeRNAi human phenotypes for NUP160:

Decreased p24 protein expressi	Nuclear 40S maturation defects	Nuclear 60S biogenesis defects	Nucleoplasmic pre-40S maturati
Synthetic lethal with Ras	Upregulation of Wnt/beta-caten

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/13 super-pathways (see all 13) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus

8/11 pathways (see all 11)
Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus	1.00	Interactions of Vpr with host cellular proteins	0.70
Nuclear import of Rev protein	0.76	Glucose transport	0.57
Vpr-mediated nuclear import of PICs	0.76	Hexose transport	0.55
Regulation of Glucokinase by Glucokinase Regulatory Protein	0.75	ISG15 antiviral mechanism	0.49

M Phase

M Phase	1.00	Mitotic Anaphase	0.85
Mitotic M-M/G1 phases	0.88	Separation of Sister Chromatids	0.80
Mitotic Metaphase and Anaphase	0.85

Resolution of Sister Chromatid Cohesion

	Resolution of Sister Chromatid Cohesion	1.00			Mitotic Prometaphase	0.93
	Kinetochore assembly	0.96

Cytokine Signaling in Immune system

Cytokine Signaling in Immune system

1.00

Interferon Signaling

0.61

HIV Infection

HIV Infection

1.00

Host Interactions of HIV factors

0.64

Pathway sources
See GeneCards unified pathways
Show all pathways

5/33 Reactome Pathways for NUP160 (see all 33)

	Mitotic Prometaphase
	Interactions of Rev with host cellular proteins
	Rev-mediated nuclear export of HIV-1 RNA
	Interferon Signaling
	Vpr-mediated nuclear import of PICs

1 Kegg Pathway (Kegg details for NUP160):

RNA transport

NUP160 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for NUP160

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/142 Interacting proteins for NUP160 (Q12769^{2, 3} ENSP00000367721⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 142)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AHCTF1	Q8WYP5²^,³, ENSP00000375705⁴	MINT-4301654 MINT-4301750 MINT-4301592 I2D: score=1 STRING: ENSP00000375705
NUP107	P57740²^,³, ENSP00000229179⁴	MINT-4301750 I2D: score=2 STRING: ENSP00000229179
DISC1	Q9NRI5³, ENSP00000355596⁴	I2D: score=2 STRING: ENSP00000355596
EXOSC1	Q9Y3B2³, ENSP00000359939⁴	I2D: score=2 STRING: ENSP00000359939
MAGED1	Q9Y5V3³, ENSP00000364847⁴	I2D: score=2 STRING: ENSP00000364847

About this table

Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000087	M phase of mitotic cell cycle	TAS	--
GO:0000236	mitotic prometaphase	TAS	--
GO:0000278	mitotic cell cycle	TAS	--
GO:0005975	carbohydrate metabolic process	TAS	--
GO:0006406	mRNA export from nucleus	IDA	11684705

NUP160 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NUP160
Search CenterWatch for drugs/clinical trials and news about NUP160 / NU160

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NUP160 gene:

NM_015231.1

Unigene Cluster for NUP160:

Nucleoporin 160kDa

Hs.744107 [show with all ESTs]

Unigene Representative Sequence: NM_015231

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000378460(uc001ngm.3 uc009ylw.3 uc021qiu.1) ENST00000530326

ENST00000532773 ENST00000528071 ENST00000526569 ENST00000527750 ENST00000528501

ENST00000531016 ENST00000527126 ENST00000532747 ENST00000526870(uc001ngn.1)

ENST00000529863

miRNA Products:		OriGene 3'-UTR Clone: NUP160 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUP160
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate NUP160 (see all 18):
		hsa-miR-1226 hsa-miR-300 hsa-miR-520d-5p hsa-miR-29a hsa-miR-29c hsa-miR-223 hsa-miR-133a hsa-miR-889

		SwitchGear 3'UTR luciferase reporter plasmid: NUP160 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUP160 (see all 6) OriGene siRNA: NUP160
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUP160

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP160 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP160 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NUP160 (NM_015231)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUP160
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP160

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUP160 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NUP160
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUP160
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP160

Additional cDNA sequence:

AK026236.1 AK302396.1 AK304308.1 AL832029.1 AL832813.1 BC008700.1 BC009822.2 BC125227.1

BC125228.1 BX647634.1 D83781.1

14 DOTS entries:

DT.415470 DT.415473 DT.95078633 DT.120693693 DT.100663615 DT.75175574 DT.91654821 DT.91755549

DT.95078606 DT.97792789 DT.97817910 DT.100716759 DT.40109761 DT.422125

24/175 AceView cDNA sequences (see all 175):

AA129745 AA477348 BU617916 AA737777 BI754892 BM449456 AA742226 AA502906

AI866872 BQ427558 BM475877 AI287295 BC008700 BX281151 AU117488 BQ023248

AW511789 CA420042 BU627107 AI269483 AI952719 BX647634 AA904475 AU130557

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NUP160 (see all 8) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16a	·	16b	^	17	^	18	^	19	^	20	^	21a	·	21b	^
SP1:							-						-																																				-
SP2:							-						-																										-										-
SP3:
SP4:
SP5:

ExUns:	22	^	23	^	24	^	25	^	26	^	27	^	28a	·	28b	^	29a	·	29b	·	29c	^	30	^	31	^	32	^	33	^	34	^	35a	·	35b	^	36	^	37	^	38a	·	38b
SP1:																			-		-								-						-
SP2:																			-		-								-						-
SP3:																					-
SP4:
SP5:

ECgene alternative splicing isoforms for NUP160

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NUP160 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCACAAGTT

About this image
See NUP160 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUP160

SOURCE GeneReport for Unigene cluster: Hs.744107

SABiosciences Custom PCR Arrays for NUP160

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUP160 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP160

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP160

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NUP160 gene from 8/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nup160^{1 , 5}	nucleoporin 160^{1, 5}	88.23(n)¹ 92.72(a)¹		2 (50.32 cM)⁵ 59015¹ NM_021512.2¹ NP_067487.1¹ 90677215⁵
chicken (Gallus gallus)	Aves	NUP160¹	nucleoporin 160kDa	70.12(n) 75.44(a)		431122 XM_001232606.2 XP_001232607.2
lizard (Anolis carolinensis)	Reptilia	NUP160⁶	--	70(a)	1 ↔ 1	1(94011136-94054379)
African clawed frog (Xenopus laevis)	Amphibia	BX843242.1²	--	77.06(n)		BX843242.1
zebrafish (Danio rerio)	Actinopterygii	zgc66306²	hypothetical protein MGC66306	73.87(n)		393635 BC057510.1
fruit fly (Drosophila melanogaster)	Insecta	CG4738³ Nup160¹	Nucleoporin 160¹	30(a)³ 43.3(n)¹ 30.83(a)¹		32D4³ 34549¹ NM_135649.1¹ NP_609493.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	ATNUP160⁶	suppressor of auxin resistance1 protein	16(a)	1 ↔ 1	1(12109590-12118850)
rice (Oryza sativa)	Liliopsida	--	expressed protein	17(a)	1 ↔ 1	2(2331667-2345503)

ENSEMBL Gene Tree for NUP160 (if available)
TreeFam Gene Tree for NUP160 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11347850^1,2	C	--	47544131(+)	`AAGGG-/AAAAAA`	1	--	int¹ trp³		1		CSA	2
rs139667867^1,2		--	47799193(+)	`CTAGTA/TGCTGG`	1	--	ds500¹		0	--	--	--	--
rs116689590^1,2	F,	--	47799210(+)	`AGGTAC/TGCACC`	1	--	ds500¹		1		WA	118
rs71308359^1,2	C	--	47799231(-)	`CTTTC-/AAAAAA`	1	--	ds500¹		1		NA	2
rs11603838^1,2	H	--	47799286(+)	`ctgatC/Ttcaag`	1	--	ds500¹		0	--	--	--	--
rs7929183^1,2	C,F,H,	--	47799372(+)	`ATACTA/GTGGGT`	1	--	ds500¹		5		NS EA WA	536
rs11608050^1,2	C,H	--	47799415(+)	`gatacA/Cctgta`	1	--	ds500¹		4		NS EA	418
rs189417841^1,2		--	47799486(+)	`ATGTCC/TTTCTT`	1	--	ds500¹		0	--	--	--	--
rs11603878^1,2	H	--	47799489(+)	`TCTTTC/TTTACT`	1	--	ds500¹		4		NS EA	418
rs9909^1,2	C,F,A,H,	--	47799775(-)	`AATCTG/CTATAC`	1	--	ut3¹ ese³		20		MN EA NA NS WA	1554

HapMap Linkage Disequilibrium report for NUP160 (47799639 - 47870107 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NUP160: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUP160

DNA2.0 Custom Variant and Variant Library Synthesis for NUP160

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NUP160 for disorders           About GeneDecksing

OMIM gene information: 607614    OMIM disorders: --

2 diseases for NUP160:    About MalaCards

schizophrenia hepatitis

Human Genome Epidemiology (HuGE) Navigator: NUP160 (1 document)

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for NUP160 gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with NUP160)

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Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. (PubMed id 11684705)^{1, 2, 3, 9} Vasu S.... Forbes D.J. (2001)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. (PubMed id 11564755)^{1, 2} Belgareh N.... Doye V. (2001)
Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)^{1, 2} Nagase T.... Nomura N. (1996)
Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. (PubMed id 22955883)¹ Bilokapic S. and Schwartz T.U. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)¹ Aichem A....Groettrup M. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23279	HGNC: 18017	AceView: NUP160	Ensembl:ENSG00000030066	euGenes: HUgn23279
ECgene: NUP160	Kegg: 23279	H-InvDB: NUP160

(According to HUGE)
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HUGE: KIAA0197

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NUP160	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NUP160 gene
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Patent Information for NUP160 gene:
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NUP160 Gene

nucleoporin 160kDa

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NUP160 Gene

nucleoporin 160kDa

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