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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUP155 Gene

protein-coding   GIFtS: 63
GCID: GC05M037327

Nucleoporin 155kDa

(Previous name: nucleoporin 155kD)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleoporin 155kDa1 2     N1552
155 KDa Nucleoporin2 3     Nuclear Pore Complex Protein Nup1552
KIAA07913 5     Nucleoporin Nup1553
Nucleoporin 155kD1     

External Ids:    HGNC: 80631   Entrez Gene: 96312   Ensembl: ENSG000001135697   OMIM: 6066945   UniProtKB: O756943   

Export aliases for NUP155 gene to outside databases

Previous GC identifers: GC05M037473 GC05M038358 GC05M037290 GC05M037337


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUP155 Gene:
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex
(NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by
this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also
be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative
splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located
on chromosome 6. (provided by RefSeq, May 2013)

GeneCards Summary for NUP155 Gene: 
NUP155 (nucleoporin 155kDa) is a protein-coding gene. Diseases associated with NUP155 include influenza, and hepatitis, and among its related super-pathways are Interactions of Rev with host cellular proteins and HIV Life Cycle. GO annotations related to this gene include structural constituent of nuclear pore and transporter activity.

UniProtKB/Swiss-Prot: NU155_HUMAN, O75694
Function: Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and
translocating proteins during nucleocytoplasmic transport (By similarity)

Gene Wiki entry for NUP155 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUP155 gene promoter:
         E2F   E2F-1   SEF-1 (1)   MIF-1   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUP155 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUP155

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP155


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13.1   Ensembl cytogenetic band:  5p13.2   HGNC cytogenetic band: 5p13.1

NUP155 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUP155 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M037327:  view genomic region     (about GC identifiers)

Start:
37,288,239 bp from pter      End:
37,371,283 bp from pter
Size:
83,045 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NU155_HUMAN, O75694 (See protein sequence)
Recommended Name: Nuclear pore complex protein Nup155  
Size: 1391 amino acids; 155199 Da
Subunit: Interacts with GLE1. Able to form a heterotrimer with GLE1 and NUPL2 in vitro. Forms a complex with
NUP53, NUP93, NUP205 and lamin B
Subcellular location: Nucleus, nuclear pore complex (By similarity). Nucleus membrane; Peripheral membrane
protein; Cytoplasmic side (By similarity). Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By
similarity). Note=In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing
back into a punctate nuclear surface localization at the end of mitosis (By similarity)
Sequence caution: Sequence=AAD52966.1; Type=Erroneous gene model prediction; Sequence=BAA34511.2; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q9UBE9 Q9UFL5
Alternative splicing: 2 isoforms:  O75694-1   O75694-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUP155: NX_O75694

Explore proteomics data for NUP155 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a
    role in the reversible disassembly of the nuclear pore complex during mitosis (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75694

  • NUP155 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUP155 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001265241.1  NP_004289.1  NP_705618.1  

    ENSEMBL proteins: 
     ENSP00000231498   ENSP00000371265   ENSP00000422019   ENSP00000423484  
    Reactome Protein details: O75694
    Human Recombinant Protein Products for NUP155: 
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    Cloud-Clone Corp. Proteins for NUP155 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope TAS--
    GO:0005643nuclear pore IEA--
    GO:0031965nuclear membrane IEA--

    NUP155 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR014908 Nucleoporin_Nup133/Nup155_N
     IPR004870 Nucleoporin_Nup155
     IPR007187 Nucleoporin_Nup133/Nup155_C

    Graphical View of Domain Structure for InterPro Entry O75694

    ProtoNet protein and cluster: O75694

    1 Blocks protein domain: IPB004870 Non-repetitive/WGA-negative nucleoporin

    UniProtKB/Swiss-Prot: NU155_HUMAN, O75694
    Similarity: Belongs to the non-repetitive/WGA-negative nucleoporin family


    NUP155 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NU155_HUMAN, O75694
    Function: Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and
    translocating proteins during nucleocytoplasmic transport (By similarity)

         Genatlas biochemistry entry for NUP155:
    nucleoporin 155 with two alternative spliced isoforms,ubiquitously expressed,component of nuclear pore
    complexes,involved in nucleocytoplasmic transport maybe involved in mental and developmental retardation in
    patients with 5p13 deletion

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity TAS10191094
    GO:0005515protein binding ----
    GO:0017056structural constituent of nuclear pore IEA--
         
    NUP155 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NUP155:
     Decreased p24 protein expressi  Nucleoplasmic pre-40S maturati 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Nup155):
     cardiovascular system  mortality/aging  nervous system 

    NUP155 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NUP155 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NUP155 
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP155


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUP155 About   (see all 11)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Glucokinase by Glucokinase Regulatory Protein
    Rev-mediated nuclear export of HIV RNA0.94
    Hexose transport0.87
    Nuclear import of Rev protein0.94
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.82
    Interactions of Rev with host cellular proteins0.94
    Nuclear Pore Complex (NPC) Disassembly0.77
    Vpr-mediated nuclear import of PICs0.91
    Nuclear Envelope Breakdown0.77
    2HIV Life Cycle
    HIV Life Cycle0.92
    HIV Infection0.61
    Late Phase of HIV Life Cycle0.92
    Host Interactions of HIV factors0.60
    3Interferon Signaling
    Interferon Signaling0.61
    Antiviral mechanism by IFN-stimulated genes0.42
    Cytokine Signaling in Immune system0.61
    ISG15 antiviral mechanism0.42
    4M Phase
    M Phase0.88
    Mitotic M-M/G1 phases0.88
    5Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/29        Reactome Pathways for NUP155 (see all 29)
        Antiviral mechanism by IFN-stimulated genes
    Late Phase of HIV Life Cycle
    Metabolism
    Cell Cycle
    M Phase


    1         Kegg Pathway  (Kegg details for NUP155):
        RNA transport


    NUP155 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NUP155

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/865 Interacting proteins for NUP155 (O756942, 3 ENSP000002314984) via UniProtKB, MINT, STRING, and/or I2D (see all 865)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSE1LP550602, 3MINT-7945693 MINT-7947479 I2D: score=1 
    DDX19AQ9NUU72, 3MINT-7945693 MINT-7947479 I2D: score=1 
    DNAJA1P316892, 3MINT-7945693 MINT-7947479 I2D: score=1 
    EEF1A1P681042, 3MINT-7945693 MINT-7947479 I2D: score=1 
    EIF2S3P410912, 3MINT-7945693 MINT-7947479 I2D: score=1 
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006406mRNA export from nucleus IEA--
    GO:0006606protein import into nucleus IEA--
    GO:0006913nucleocytoplasmic transport ----

    NUP155 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUP155 (NU155)

    Search CenterWatch for drugs/clinical trials and news about NUP155 / NU155

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUP155 gene (3 alternative transcripts): 
    NM_001278312.1  NM_004298.3  NM_153485.2  

    Unigene Cluster for NUP155:

    Nucleoporin 155kDa
    Hs.547696  [show with all ESTs]
    Unigene Representative Sequence: BC039257
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000231498(uc003jku.1 uc010iuz.1) ENST00000508182 ENST00000502533
    ENST00000381843(uc003jkt.1) ENST00000513532 ENST00000515054 ENST00000507233
    ENST00000507675
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): NUP155 (NM_153485)
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    Additional mRNA sequence: 

    AB018334.1 AJ007558.1 AK002103.1 AK297143.1 AK315028.1 AL117585.1 BC039257.1 

    8 DOTS entries:

    DT.95289375  DT.445153  DT.92426539  DT.100776132  DT.95162636  DT.100666563  DT.100666565  DT.91951648 

    24/117 AceView cDNA sequences (see all 117):

    BU176332 AL117585 BM787539 BQ687298 AW675076 AJ007558 BU168705 CB115747 
    BQ688187 CB128932 AA360396 BM722987 BQ881620 AL526137 BX107078 AB018334 
    BE883863 T36125 CB119433 NM_004298 NM_153485 BU158618 BG546764 BQ069383 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NUP155    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^
    SP1:        -                                                                                                                                                   
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            

    ExUns: 27 ^ 28 ^ 29 ^ 30 ^ 31a · 31b ^ 32 ^ 33 ^ 34 ^ 35a · 35b ^ 36a · 36b
    SP1:                                -                       -                     
    SP2:                                -                       -                     
    SP3:                                                                              
    SP4:                                                                              


    ECgene alternative splicing isoforms for NUP155

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUP155 expression in normal human tissues (normalized intensities)      NUP155 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTATTGAT
    NUP155 Expression
    About this image


    NUP155 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium

    See NUP155 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUP155

    SOURCE GeneReport for Unigene cluster: Hs.547696

    UniProtKB/Swiss-Prot: NU155_HUMAN, O75694
    Tissue specificity: Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal
    muscle, kidney and pancreas

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP155

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NUP155 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nup1551 , 5 nucleoporin 1551, 5 87.56(n)1
    94.96(a)1
      15 (3.82 cM)5
    1707621  NM_133227.31  NP_573490.31 
     81093135 
    chicken
    (Gallus gallus)
    Aves NUP1551 nucleoporin 155kDa 78.5(n)
    86.09(a)
      427443  XM_425016.2  XP_425016.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    84(a)
    82(a)
    (see all 3)
    many → 1
    many → 1
    (see all 3)
    GL343241.1(955151-972195)
    GL343241.1(929682-951461)
    African clawed frog
    (Xenopus laevis)
    Amphibia nup155-prov2 nucleoporin 155kDa 75.01(n)    BC047162.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc554352 similar to nucleoporin 155 73.19(n)   393125  BC045339.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nup1541 , 3 Nucleoporin 1541 31(a)3
    45.92(n)1
    36.13(a)1
      345271  NM_057939.31  NP_477287.11 
    worm
    (Caenorhabditis elegans)
    Secernentea npp-81 Protein NPP-8 41.33(n)
    30.22(a)
      176966  NM_067701.4  NP_500102.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NUP170(YBL079W)4
    NUP1701
    Subunit of the nuclear pore complex (NPC), required more4
    Nup170p1
    41.65(n)1
    26.19(a)1
      2(75259-79767)4
    8521991, 4  NP_009474.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NUP1551 nucleoporin 155 43.41(n)
    30.05(a)
      838050  NM_101354.2  NP_172938.2 
    rice
    (Oryza sativa)
    Liliopsida Os06g03052001 hypothetical protein 43.85(n)
    30.66(a)
      4340842  NM_001064003.1  NP_001057468.1 


    ENSEMBL Gene Tree for NUP155 (if available)
    TreeFam Gene Tree for NUP155 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUP155 gene

    NUP155 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NUP155
    PGOHUM00000243255


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1766 SNPs in NUP155 are shown (see all 1766)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2163901,2
    F--37235813(+) gattcG/Acctcc 2 -- ds50011Minor allele frequency- A:0.00NA 2
    rs1461336601,2
    --37235942(+) GCCTCA/GTGATT 2 -- ds50010--------
    rs1843093691,2
    --37235986(+) CAGGTG/TTAAGT 2 -- ds50010--------
    rs1996865291,2
    C--37236110(+) CTAAA-/TTTTTT 2 -- ds50010--------
    rs1892652571,2
    C--37236302(+) GATATC/TTGGAC 2 -- ut310--------
    rs1810028811,2
    C--37236322(+) TTTTTA/GTTTTA 2 -- ut310--------
    rs1863821381,2
    C--37236340(+) TAAAAC/TGGATG 2 -- ut310--------
    rs2163911,2
    C,F,H--37236344(+) ACGGAT/CGAAAG 2 -- ut31 ese36Minor allele frequency- C:0.01EA NA NS WA EU 1597
    rs2021941941,2
    C--37236373(+) GAAGCC/TGTTCT 4 Q R mis10--------
    rs1896157541,2
    C--37236432(+) ACTGAC/TGAGCT 4 S syn10--------

    HapMap Linkage Disequilibrium report for NUP155 (37288239 - 37371283 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for NUP155 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2671337CNV Deletion23128226
    esv2730083CNV Deletion23290073
    esv2496620CNV Deletion19546169
    esv2270645CNV Deletion18987734
    dgv29e194CNV Deletion18987734
    nsv328371CNV Loss16902084
    nsv329973CNV Loss16902084
    nsv830265CNV Loss17160897
    nsv525478CNV Loss19592680
    nsv881076CNV Gain21882294


    Human Gene Mutation Database (HGMD): NUP155
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NUP155
    DNA2.0 Custom Variant and Variant Library Synthesis for NUP155

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606694    OMIM disorders: --

    2 diseases for NUP155:    About MalaCards
    influenza    hepatitis


    NUP155 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NUP155
    Human Genome Epidemiology (HuGE) Navigator: NUP155 (1 document)

    Export disorders for NUP155 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUP155 gene, integrated from 9 sources (see all 52):
    (articles sorted by number of sources associating them with NUP155)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Localization of a human nucleoporin 155 gene (NUP155) to the 5p13 region and cloning of its cDNA. (PubMed id 10191094)1, 2, 3 Zhang X.... Bolund L. (1999)
    2. Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. (PubMed id 15703211)1, 2, 9 Hawryluk-Gara L.A.... Wozniak R.W. (2005)
    3. The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155. (PubMed id 14645504)1, 2, 9 Rayala H.J.... Wente S.R. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene. (PubMed id 12034489)1, 2 Zhang X.... Bolund L. (2002)
    6. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
    7. Novel, gel-free proteomics approach identifies RNF5 an d JAMP as modulators of GPCR stability. (PubMed id 23798571)1 Roy S.J....Parent J.L. (2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. (PubMed id 22412018)1 Roux K.J.... Burke B. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9631 HGNC: 8063 AceView: NUP155 Ensembl:ENSG00000113569 euGenes: HUgn9631
    ECgene: NUP155 Kegg: 9631 H-InvDB: NUP155

    (According to HUGE)
    About This Section
    HUGE: KIAA0791

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUP155 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUP155 gene:
    Search GeneIP for patents involving NUP155

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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