Aliases for NUP155 Gene
External Ids for NUP155 Gene
Previous GeneCards Identifiers for NUP155 Gene
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]
GeneCards Summary for NUP155 Gene
NUP155 (Nucleoporin 155kDa) is a Protein Coding gene. Diseases associated with NUP155 include atrial fibrillation 15 and atrial septal defect 9. Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include transporter activity and structural constituent of nuclear pore.
UniProtKB/Swiss-Prot for NUP155 Gene
Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.