NUP153 Gene
protein-coding GIFtS: 57
GCID: GC06M017559
|
|
nucleoporin 153kDa(Previous name: nucleoporin 153kD )
| |
Aliases
for NUP153 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nucleoporin 153kDa1 2 | | Nucleoporin 153kD1 | | HNUP1531 2 | | N1532 | | Nucleoporin Nup1532 3 | | Nuclear Pore Complex Protein Hnup1532 | | 153 KDa Nucleoporin2 3 | | Nuclear Pore Complex Protein Nup1532 |
Export aliases for NUP153 gene to outside databasesPrevious GC identifers: GC06M017672 GC06M017723 |
Summaries
for NUP153 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NUP153:
Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules betweenthe nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of whichbelong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized bycytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequenceXFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targetingdomain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal regioncontaining multiple XFXFG repeats. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NU153_HUMAN, P49790Function: Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involvedin anchoring components of the pore complex to the pore membrane
Gene Wiki entry for NUP153
|
Genomic Views
for NUP153 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NUP153 gene promoter:
AhR TBP HFH-3 FOXD3 POU6F1 (c2) LCR-F1 C/EBPalpha FOXI1 IRF-2 FOXC1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUP153
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP153 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.3 Ensembl cytogenetic band: 6p22.3 HGNC cytogenetic band: 6p22.3NUP153 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M017559: view genomic region
(about GC identifiers)
Start:
|
17,615,269 bp from pter |
End:
|
17,706,818 bp from pter |
Size:
|
91,550 bases |
Orientation:
|
minus strand |
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Proteins
for NUP153 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NU153_HUMAN, P49790 (See
protein sequence)Recommended Name: Nuclear pore complex protein Nup153 Size: 1475 amino acids; 153938 Da
Subunit: Interacts with SENP2 and XPO5. Interacts with HIV-1 integrase; this interaction might play a role in nuclearimport of HIV pre-integration complex. Interacts with hepatitis B virus capsid protein; this interaction probablyplays a role in nuclear import of HBV genome. Interacts with C11orf73/Hikeshi
Subcellular location: Nucleus, nuclear pore complex. Note=Located to the terminal ring structure of the nucleoplasmiccage. Tightly associated with the nuclear membrane and lamina (By similarity)
4 PDB 3D structures from  and Proteopedia  for NUP153:2EBQ (3D)
2EBR (3D)
2EBV (3D)
2GQE (3D)
Secondary accessions: Q5T9I7Explore the universe of human proteins at neXtProt for NUP153: NX_P49790
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49790
NUP153 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005115.2
ENSEMBL proteins: ENSP00000262077 ENSP00000444029 Reactome Protein details: P49790
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
NUP153 for ontologies About GeneDecksing
NUP153 Antibody Products:
Assay Products for NUP153: |
Protein
Domains /
Families
for NUP153 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUP153 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49790ProtoNet protein and cluster: P49790 2 Blocks protein families: IPB001876 Zn-finger IPB013913 Nucleoporin Nup153-like
UniProtKB/Swiss-Prot: NU153_HUMAN, P49790Domain: Contains F-X-F-G repeatsSimilarity: Contains 4 RanBP2-type zinc fingers |
Function
for NUP153 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NU153_HUMAN, P49790Function: Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involvedin anchoring components of the pore complex to the pore membrane
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NUP153 (NM_005124) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUP153 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP153 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP153 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
NUP153 for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for NUP153:
|
Pathways & Interactions
for NUP153 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus | | | 2 | Cytokine Signaling in Immune system | | | 3 | HIV Infection | | | 4 | SLC-mediated transmembrane transport | | | 5 | Late Phase of HIV Life Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for NUP153
5/23 
Reactome Pathways for NUP153 (see all 23)
1 
Kegg Pathway (Kegg details for NUP153):
NUP153 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NUP153
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/633 Interacting proteins for NUP153 (P497902, 3 ENSP000002620774) via UniProtKB, MINT, STRING, and/or I2D (see all 633)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| EPHB2 | P293232, 3, ENSP000003637634 | MINT-4300391 MINT-4300355 I2D:
score=1 STRING: ENSP00000363763 | | KPNB1 | Q149742, 3, ENSP000002901584 | MINT-7945693 I2D:
score=3 STRING: ENSP00000290158 | | NXF1 | Q9UBU92, 3, ENSP000002941724 | MINT-15627 I2D:
score=3 STRING: ENSP00000294172 | | KPNA2 | P522922, 3, ENSP000003324554 | MINT-7945693 I2D:
score=1 STRING: ENSP00000332455 | | LMNA | P025452, 3, ENSP000003572834 | MINT-7945693 MINT-7893777 I2D:
score=1 STRING: ENSP00000357283 |
About this table
Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16): About this table
NUP153 for ontologies About GeneDecksing
|
Drugs & Compounds
for NUP153 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NUP153 for compounds About GeneDecksing
 Browse Tocris compounds for NUP153
3 Novoseek chemical compound relationships for NUP153 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| zinc |
27.4 |
4 |
16314393 (2), 8110839 (1) |
| actinomycin d |
26.4 |
1 |
9847314 (1) |
| pyruvate |
15 |
1 |
8794857 (1) |
Search CenterWatch for drugs/clinical trials and news about NUP153 / NU153
|
Transcripts
for NUP153 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NUP153 gene: NM_005124.2 Unigene Clusters for NUP153: Nucleoporin 153kDa Hs.601591 [show with all ESTs], Hs.718703 [show with all ESTs]Unigene Representative Sequences: AB210024, BM9130962 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262077(uc003ncd.1 uc011dje.1 uc010jpl.1) ENST00000537253
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NUP153 (NM_005124) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUP153 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP153 |
Additional cDNA sequence: BC035502.2 BC046172.1 16 DOTS entries: DT.446927 DT.434816 DT.99971020 DT.102824068 DT.121337199 DT.441584 DT.95148921 DT.95276137 DT.100668485 DT.100736910 DT.100783295 DT.121337101 DT.121337117 DT.121337129 DT.95276139 DT.97823514 24/284 AceView cDNA sequences (see all 284): BM761269 AA653168 AA565507 BU681292 F13065 AL043770 AA319183 AI983129 AI654426 AW136213 BE503034 AI057347 AL043523 NM_005124 F10659 AI568716 BM090979 AI804359 AI246397 AA361049 AL040791 BM451049 AA700100 T09409
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for NUP153 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for NUP153
|
Expression
for NUP153 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NUP153 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCCTTAGAA
About this image
See NUP153 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUP153
SOURCE GeneReport for Unigene clusters: Hs.601591 Hs.718703
SABiosciences Custom PCR Arrays for NUP153
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUP153
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NUP153 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUP153 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP153 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP153 |
Orthologs
for NUP153 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for NUP153 gene from 7/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NUP1531 |
nucleoporin 153kDa |
70.31(n)
66.76(a) |
|
420848 XM_418937.3 XP_418937.3 |
lizard
(Anolis carolinensis) |
Reptilia |
NUP1536 |
-- |
45(a) |
1 ↔ 1 |
4(59114621-59142860) |
African clawed frog
(Xenopus laevis) |
Amphibia |
NUP1532 |
nucleoporin Nup153 |
76.36(n) |
|
AF434196.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufd23d092 |
Transcribed sequence with weak similarity to protein more |
88.52(n) |
|
57057051 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Nup1531 |
Nucleoporin 153 |
39.09(n)
30.57(a) |
|
32630 NM_001103532.2 NP_001097002.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
NUP966 |
suppressor of auxin resistance 3 |
4(a) |
1 → many |
1(30324008-30328769) |
rice
(Oryza sativa) |
Liliopsida |
-- |
OsNucAP1 - Putative Nucleoporin Autopeptidase homo... |
4(a) |
1 → many |
3(3858381-3863721) |
ENSEMBL Gene Tree for NUP153 (if available)
TreeFam Gene Tree for NUP153 (if available) |
Paralogs
for NUP153 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NUP153 gene
- NUP2142 POM121C2 ENSG000001823562 POM121L72 POM121L1P2 POM1212 POM121L4P2 POM121L22
1 SIMAP similar gene for NUP153 using alignment to 3 protein entries: NU153_HUMAN (see all proteins):NUP153 variant protein
NUP153 for paralogs About GeneDecksing
|
Genomic Variants
for NUP153 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NUP153 (17615269 - 17706818 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NUP153
1 CNV: 4486 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUP153 |
|
Disorders
/ Diseases
for NUP153 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NUP153 for disorders About GeneDecksing
OMIM gene information: 603948
OMIM disorders: --
4  diseases for NUP153: About MalaCardshemophagocytic lymphohistiocytosis infectious mononucleosis immunodeficiency hepatitis
1 Novoseek disease relationship for NUP153 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| immunodeficiency |
1.21 |
1 |
19369352 (1) |
Human Genome Epidemiology (HuGE) Navigator: NUP153 (2 documents)
Export disorders for NUP153 gene to outside databases
|
Publications
for NUP153 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUP153 gene, integrated from 9 sources (see all 119):
(articles sorted by number of sources associating them with NUP153) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sequence analysis of a cDNA encoding a human nuclear pore complex protein, hnup153. (PubMed id 8110839)1, 2, 3, 9 McMorrow I.... Burke B. (1994)
- Integrase interacts with nucleoporin NUP153 to mediat e the nuclear import of human immunodeficiency virus type 1. (PubMed id 19369352)1, 2, 9 Woodward C.L....Chow S.A. (2009)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Exportin-5, a novel karyopherin, mediates nuclear export of double- stranded RNA binding proteins. (PubMed id 11777942)1, 2 Brownawell A.M. and Macara I.G. (2002)
- The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. (PubMed id 11598013)1, 9 Walther T.C....Mattaj I.W. (2001)
- The functionally conserved nucleoporins Nup124p from fission yeast and the human Nup153 mediate nuclear import and activity of the Tf1 retrotransposon and HIV-1 Vpr. (PubMed id 15659641)1, 9 Varadarajan P....Balasundaram D. (2005)
- Carrier-independent nuclear import of the transcription factor PU.1 via RanGTP-stimulated binding to Nup153. (PubMed id 15632149)1, 9 Zhong H....Yaseen N.R. (2005)
- Oxidative stress mislocalizes and retains transport factor importin-alpha and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes. (PubMed id 18068677)1, 9 Kodiha M....Stochaj U. (2008)
- Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility. (PubMed id 14718558)1, 9 Griffis E.R....Powers M.A. (2004)
|
External Searches for NUP153 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NUP153 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUP153 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUP153 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NUP153 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NUP153 gene:
Search GeneIP for patents involving NUP153
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NUP153 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NUP153 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUP153 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUP153 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NUP153 | | OriGene 3'-UTR Clone for NUP153 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUP153 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NUP153 | | OriGene Custom Protein Services for NUP153 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NUP153 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUP153 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUP153 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUP153 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUP153 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUP153 |
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| | | | Search Tocris compounds for NUP153 |
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 | | | NUP153 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP153 |
|  |  |  | | | | ThermoFisher Antibodies for NUP153 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUP153 |
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