Aliases for NUP133 Gene
External Ids for NUP133 Gene
Previous GeneCards Identifiers for NUP133 Gene
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for NUP133 Gene
NUP133 (Nucleoporin 133) is a Protein Coding gene. Diseases associated with NUP133 include Galloway-Mowat Syndrome. Among its related pathways are HIV Life Cycle and Transport of the SLBP independent Mature mRNA. GO annotations related to this gene include nucleocytoplasmic transporter activity.
UniProtKB/Swiss-Prot for NUP133 Gene
Involved in poly(A)+ RNA transport.