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NUP107 Gene

protein-coding   GIFtS: 62
GCID: GC12P069080

Nucleoporin 107kDa

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nucleoporin 107kDa1 2
Nucleoporin Nup1072 3
107 KDa Nucleoporin2 3
NUP842 5
Nuclear Pore Complex Protein Nup1072

External Ids:    HGNC: 299141   Entrez Gene: 571222   Ensembl: ENSG000001115817   OMIM: 6076175   UniProtKB: P577403   

Export aliases for NUP107 gene to outside databases

Previous GC identifers: GC12P069331 GC12P068884 GC12P068797 GC12P067366 GC12P066131


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NUP107 Gene:
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an
essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either
diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene
have been observed but have not been thoroughly characterized. (provided by RefSeq, Jul 2008)

GeneCards Summary for NUP107 Gene:
NUP107 (nucleoporin 107kDa) is a protein-coding gene. Diseases associated with NUP107 include mesenchymal chondrosarcoma, and chondrosarcoma. GO annotations related to this gene include nucleocytoplasmic transporter activity and structural constituent of nuclear pore.

UniProtKB/Swiss-Prot: NU107_HUMAN, P57740
Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of
peripheral proteins into the NPC. May anchor NUP62 to the NPC

Gene Wiki entry for NUP107 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NUP107 gene promoter:
         E2F-3a   Elk-1   AML1a   FOXD3   E2F-2   STAT5A   POU2F1   E2F   E2F-1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUP107 promoter sequence
   Search Chromatin IP Primers for NUP107

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NUP107


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q15   Ensembl cytogenetic band:  12q15   HGNC cytogenetic band: 12q14

NUP107 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUP107 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P069080:  view genomic region     (about GC identifiers)

Start:
69,080,514 bp from pter      End:
69,136,785 bp from pter
Size:
56,272 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NU107_HUMAN, P57740 (See protein sequence)
Recommended Name: Nuclear pore complex protein Nup107  
Size: 925 amino acids; 106374 Da
Subunit: Part of the nuclear pore complex (NPC). Forms part of the Nup160 subcomplex in the nuclear pore which is
composed of NUP160, NUP133, NUP107 and Nup96; this complex plays a role in RNA export and in tethering Nup98 and
NUP153 to the nucleus. Does not interact with TPR
3 PDB 3D structures from and Proteopedia for NUP107:
3CQC (3D)        3CQG (3D)        3I4R (3D)    

Explore the universe of human proteins at neXtProt for NUP107: NX_P57740

Explore proteomics data for NUP107 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys85, Lys305, Lys332, Lys348, Lys382, Lys408, Lys637, Lys690, Lys773
  • Modification sites at PhosphoSitePlus

  • See NUP107 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065134.1  
    ENSEMBL proteins: 
     ENSP00000229179   ENSP00000445567   ENSP00000441448   ENSP00000440116   ENSP00000441334  
     ENSP00000368185  
    Reactome Protein details: P57740

    NUP107 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007252 Nup84_Nup100

    Graphical View of Domain Structure for InterPro Entry P57740

    ProtoNet protein and cluster: P57740

    1 Blocks protein domain: IPB007252 Nuclear pore protein 84/107

    UniProtKB/Swiss-Prot: NU107_HUMAN, P57740
    Similarity: Belongs to the nucleoporin Nup84/Nup107 family


    NUP107 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NU107_HUMAN, P57740
    Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of
    peripheral proteins into the NPC. May anchor NUP62 to the NPC

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005487nucleocytoplasmic transporter activity IDA11684705
    GO:0005515protein binding IPI11564755
    GO:0017056structural constituent of nuclear pore IMP15229283
         
    NUP107 for ontologies           About GeneDecksing


    Phenotypes:
         10 GenomeRNAi human phenotypes for NUP107:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased TP53 protein express 
     Decreased influenza A virus in  Decreased p24 protein expressi  G0/1 arrest  Increased G1 DNA content 
     Increased gamma-H2AX phosphory  Nucleoplasmic pre-40S maturati 

    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target NUP107:
    hsa-mir-93-5p (MIRT028013)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NU107_HUMAN, P57740: Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore.
    Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure. During mitosis, localizes to
    the kinetochores. Dissociates from the dissasembled NPC structure late during prophase of mitosis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776colocalizes with kinetochore IDA17363900
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005634nucleus IDA--
    GO:0005635nuclear envelope TAS--
    GO:0005643nuclear pore IDA11564755

    NUP107 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NUP107 About   (see all 17)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Regulation of Glucokinase by Glucokinase Regulatory Protein
    Transport of the SLBP Dependant Mature mRNA0.92
    Export of Viral Ribonucleoproteins from Nucleus0.88
    Transport of Mature mRNAs Derived from Intronless Transcripts0.92
    Transport of Ribonucleoproteins into the Host Nucleus0.88
    Transport of the SLBP independent Mature mRNA0.91
    Regulation of Glucokinase by Glucokinase Regulatory Protein0.87
    Nuclear import of Rev protein0.91
    Glucose transport0.87
    2HIV Life Cycle
    HIV Life Cycle0.91
    HIV Infection0.62
    Late Phase of HIV Life Cycle0.91
    Host Interactions of HIV factors0.60
    3Interferon Signaling
    Interferon Signaling0.59
    ISG15 antiviral mechanism0.42
    Cytokine Signaling in Immune system0.59
    Antiviral mechanism by IFN-stimulated genes0.42
    4Mitotic Metaphase and Anaphase
    Mitotic Anaphase0.94
    Mitotic Metaphase and Anaphase0.93
    Separation of Sister Chromatids0.94
    5Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for NUP107
        Gastric cancer network 1

    Selected Reactome Pathways for NUP107 (see all 9)
        Rev-mediated nuclear export of HIV RNA
    Regulation of Glucokinase by Glucokinase Regulatory Protein
    Nuclear Pore Complex (NPC) Disassembly
    Nuclear import of Rev protein
    Resolution of Sister Chromatid Cohesion


    1 Kegg Pathway  (Kegg details for NUP107):
        RNA transport


    NUP107 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NUP107
    Interactions:

        GeneGlobe Interaction Network for NUP107

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NUP107 (P577401, 2, 3 ENSP000002291794) via UniProtKB, MINT, STRING, and/or I2D (see all 756)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AHCTF1Q8WYP52, 3, ENSP000003757054MINT-4301709 MINT-4301750 MINT-4301632 MINT-4301665 I2D: score=1 STRING: ENSP00000375705
    NUP160Q127692, 3, ENSP000003677214MINT-4301750 I2D: score=2 STRING: ENSP00000367721
    NUP214P356582, 3, ENSP000003524004MINT-4301750 I2D: score=2 STRING: ENSP00000352400
    NUP133Q8WUM01, 2, 3, ENSP000002613964EBI-295687,EBI-295695 MINT-4788188 MINT-4788150 I2D: score=3 STRING: ENSP00000261396
    NUP93Q8N1F72, 3, ENSP000003106684MINT-4301728 MINT-7947479 I2D: score=1 STRING: ENSP00000310668
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0005975carbohydrate metabolic process TAS--
    GO:0006406mRNA export from nucleus IDA11684705
    GO:0006810transport ----
    GO:0007077mitotic nuclear envelope disassembly TAS--

    NUP107 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NUP107 (NU107)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NUP107 gene: 
    NM_020401.2  

    Unigene Cluster for NUP107:

    Nucleoporin 107kDa
    Hs.524574  [show with all ESTs]
    Unigene Representative Sequence: NM_020401
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000229179(uc001suf.3 uc001sug.3) ENST00000540453 ENST00000535333
    ENST00000537598 ENST00000535718 ENST00000539906(uc010stj.2) ENST00000538549
    ENST00000545140 ENST00000539373 ENST00000537662 ENST00000538993 ENST00000401003
    ENST00000378905
    miRNA
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    GenScript: all cDNA clones in your preferred vector: NUP107 (NM_020401)
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      QuantiTect SYBR Green Assays in human, mouse, rat NUP107
      QuantiFast Probe-based Assays in human, mouse, rat NUP107

    Additional mRNA sequence: 

    AJ295745.1 AK002079.1 AK055629.1 AK094183.1 AK302773.1 AK315157.1 BC017167.2 BC017670.1 
    BC043343.2 

    13 DOTS entries:

    DT.110497  DT.121181885  DT.100792449  DT.95121844  DT.91754513  DT.100792455  DT.40251485  DT.92067869 
    DT.95121837  DT.95121838  DT.95093819  DT.95121839  DT.95279810 

    Selected AceView cDNA sequences (see all 180):

    AJ295745 CB995646 AW020132 AK094183 NM_020401 AA580884 BI089306 AA772692 
    CA488408 CD300596 CB115722 AI620111 BU679662 BC043343 BI962696 AK055629 
    BE891215 CB118763 CA489723 BP358551 CA423447 BX118119 AA362557 BP374292 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NUP107 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:                                -     -     -                                                           -                                                   
    SP2:                                -     -     -           -                                               -                                                   
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                -     -                                                                                                                     

    ExUns: 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28
    SP1:                                                      
    SP2:        -     -                                       
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for NUP107

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NUP107 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGGGATATC
    NUP107 Expression
    About this image


    NUP107 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    NUP107 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NUP107 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.524574
        Custom PCR Arrays for NUP107
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUP107

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for NUP107 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nup1071 , 5 nucleoporin 1071, 5 84.81(n)1
    91.45(a)1
      10 (66.32 cM)5
    1034681  NM_134010.21  NP_598771.11 
     1177506435 
    chicken
    (Gallus gallus)
    Aves NUP1071 nucleoporin 107kDa 76.19(n)
    81.24(a)
      101751988  XM_004937564.1  XP_004937621.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUP1076
    nucleoporin 107kDa
    65(a)
    1 ↔ 1
    GL343256.1(1379501-1432305)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.161962 Xenopus laevis transcribed sequence with weak similarity more 76.28(n)    BU910269.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nup1071 nucleoporin 107 65.89(n)
    68.73(a)
      562350  NM_001030167.1  NP_001025338.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BcDNA:LD187613
    Nup1071
    Nucleoporin 1071 33(a)3
    43.09(n)1
    35.94(a)1
      32A43
    344811  NM_135602.31  NP_609446.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NUP84(YDL116W)4 Subunit of the nuclear pore complex (NPC); forms a more   --   4(251566-253746) 851441  NP_010167.1 


    ENSEMBL Gene Tree for NUP107 (if available)
    TreeFam Gene Tree for NUP107 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NUP107 (see all 1052)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs350793561,2
    C--69082651(+) CTTAC-/TCAGGG 1 -- int11Minor allele frequency- T:0.00NA 2
    rs22595921,2
    C,F,A,H--69082669(-) CACAGT/CTGGAG 1 -- int129Minor allele frequency- C:0.32NA NS EA WA CSA 2912
    rs1844306481,2
    --69082690(+) TCTTTA/CTAAAT 1 -- int10--------
    rs1892562451,2
    C--69082761(+) AGATAC/TCATCC 2 P S mis10--------
    rs22595881,2
    C,F,H--69082805(-) TGTTTC/TCGTGC 2 R syn117Minor allele frequency- T:0.21NA NS EA CSA WA EU 6871
    rs2016094711,2
    C--69082824(+) AGAAAA/GGAGTT 2 R G mis10--------
    rs2011359861,2
    C--69082857(+) GCATCA/GTTATA 1 -- int10--------
    rs1820032861,2
    --69082954(+) ACTTTG/TTTTCA 1 -- int10--------
    rs25465091,2
    C,F,O--69083237(-) TACTAT/CACAAA 1 -- int110Minor allele frequency- C:0.19NA CSA WA EA 506
    rs1419182341,2
    --69083245(+) GTAAAA/GAGATG 1 -- int10--------

    HapMap Linkage Disequilibrium report for NUP107 (69080514 - 69136785 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NUP107:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv510302CNV Loss20534489
    nsv759CNV Loss18451855
    nsv522941CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NUP107
    DNA2.0 Custom Variant and Variant Library Synthesis for NUP107

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607617    OMIM disorders: --

    9 diseases for NUP107:    
    About MalaCards
    mesenchymal chondrosarcoma    chondrosarcoma    influenza    tonsillitis
    hiv-1    hepatitis    malaria    cerebritis
    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for NUP107:
    Mesenchymal chondrosarcoma

    NUP107 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NUP107
    Human Genome Epidemiology (HuGE) Navigator: NUP107 (1 document)

    Export disorders for NUP107 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NUP107 gene, integrated from 10 sources (see all 57):
    (articles sorted by number of sources associating them with NUP107)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex. (PubMed id 12552102)1, 2, 3 Boehmer T.... Zhong H. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    2. Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. (PubMed id 15229283)1, 2, 9 Krull S.... Cordes V.C. (Mol. Biol. Cell 2004)
    3. Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. (PubMed id 11684705)1, 2, 9 Vasu S.... Forbes D.J. (J. Cell Biol. 2001)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The conserved Nup107-160 complex is critical for nuclear pore complex assembly. (PubMed id 12705868)1, 3 Walther T.C....Doye V. (Cell 2003)
    8. Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex. (PubMed id 12802065)1, 2 Hase M.E. and Cordes V.C. (Mol. Biol. Cell 2003)
    9. An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. (PubMed id 11564755)1, 2 Belgareh N.... Doye V. (J. Cell Biol. 2001)
    10. Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex. (PubMed id 9166401)1, 9 Bastos R....Burke B. (J. Cell Biol. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57122 HGNC: 29914 AceView: NUP107 Ensembl:ENSG00000111581 euGenes: HUgn57122
    ECgene: NUP107 Kegg: 57122 H-InvDB: NUP107

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NUP107 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NUP107 gene:
    Search GeneIP for patents involving NUP107

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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