Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUFIP1 Gene

protein-coding   GIFtS: 49
GCID: GC13M045513

Nuclear Fragile X Mental Retardation Protein Interacting...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nuclear Fragile X Mental Retardation Protein Interacting Protein 11 2
Nuclear FMRP-Interacting Protein 12 3
NUFIP2 5
bA540M5.12
Nuclear Fragile X Mental Retardation-Interacting Protein 12

External Ids:    HGNC: 80571   Entrez Gene: 267472   Ensembl: ENSG000000836357   OMIM: 6043545   UniProtKB: Q9UHK03   

Export aliases for NUFIP1 gene to outside databases

Previous GC identifers: GC13M043513 GC13M039499 GC13M044450 GC13M043311 GC13M044411 GC13M026315


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUFIP1 Gene:
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization
signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to
the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X
mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II
transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome
6q12. (provided by RefSeq, Feb 2012)

GeneCards Summary for NUFIP1 Gene: 
NUFIP1 (nuclear fragile X mental retardation protein interacting protein 1) is a protein-coding gene. Diseases associated with NUFIP1 include mental retardation, and intellectual disability. GO annotations related to this gene include RNA binding and protein binding, bridging.

UniProtKB/Swiss-Prot: NUFP1_HUMAN, Q9UHK0
Function: Binds RNA

Gene Wiki entry for NUFIP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUFIP1 gene promoter:
         AP-2rep   SRF   Max1   SRF (504 AA)   CUTL1   PPAR-gamma1   GATA-6   HSF2   PPAR-gamma2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUFIP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUFIP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUFIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14   Ensembl cytogenetic band:  13q14.12   HGNC cytogenetic band: 13q14

NUFIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUFIP1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M045513:  view genomic region     (about GC identifiers)

Start:
45,513,384 bp from pter      End:
45,563,618 bp from pter
Size:
50,235 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUFP1_HUMAN, Q9UHK0 (See protein sequence)
Recommended Name: Nuclear fragile X mental retardation-interacting protein 1  
Size: 495 amino acids; 56300 Da
Subunit: Interacts with FMR1
Subcellular location: Nucleus. Note=Distributed in the nucleus in a dot-like pattern
Sequence caution: Sequence=AAH17745.1; Type=Erroneous initiation;
Secondary accessions: Q8WVM5 Q96SG1

Explore the universe of human proteins at neXtProt for NUFIP1: NX_Q9UHK0

Explore proteomics data for NUFIP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UHK0

  • NUFIP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUFIP1 Protein Expression
    REFSEQ proteins: NP_036477.2  
    ENSEMBL proteins: 
     ENSP00000368459  

    Human Recombinant Protein Products for NUFIP1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for NUFIP1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for NUFIP1
    GenScript Custom Purified and Recombinant Proteins Services for NUFIP1
    Novus Biologicals NUFIP1 Protein
    Novus Biologicals NUFIP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NUFIP1 

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005726perichromatin fibrils IDA12941608
    GO:0005730nucleolus IDA--
    GO:0008023transcription elongation factor complex IDA15107825
    GO:0016363nuclear matrix IDA12941608

    NUFIP1 for ontologies           About GeneDecksing



    NUFIP1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NUFIP1
    GenScript Custom Superior Antibodies Services for NUFIP1
    Novus Biologicals NUFIP1 Antibodies
    Abcam antibodies for NUFIP1
    Cloud-Clone Corp. Antibodies for NUFIP1 
    ThermoFisher Antibodies for NUFIP1
    LSBio Antibodies in human, mouse, rat for NUFIP1 

    Assay Products for NUFIP1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NUFIP1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NUFIP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NUFIP1 
    Cloud-Clone Corp. CLIAs for NUFIP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR019496 NUFIP1_cons_dom
     IPR015880 Znf_C2H2-like
     IPR007087 Znf_C2H2
     IPR022755 Znf_C2H2_jaz

    Graphical View of Domain Structure for InterPro Entry Q9UHK0

    ProtoNet protein and cluster: Q9UHK0

    UniProtKB/Swiss-Prot: NUFP1_HUMAN, Q9UHK0
    Similarity: Contains 1 C2H2-type zinc finger


    NUFIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUFP1_HUMAN, Q9UHK0
    Function: Binds RNA

         Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS15107825
    GO:0003723RNA binding IDA10556305
    GO:0005515protein binding IPI10556305
    GO:0008270zinc ion binding ----
    GO:0030515contributes to snoRNA binding IDA17636026
         
    NUFIP1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NUFIP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NUFIP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NUFIP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NUFIP1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUFIP1
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate NUFIP1 (see all 10):
    hsa-miR-4254 hsa-miR-448 hsa-miR-548e hsa-miR-548v hsa-miR-545 hsa-miR-4275 hsa-miR-153 hsa-miR-548a-3p
    SwitchGear 3'UTR luciferase reporter plasmidNUFIP1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NUFIP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUFIP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NUFIP1
    Sirion Biotech Customized adenovirus for overexpression of NUFIP1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NUFIP1 (see all 7)
    OriGene ORF clones in mouse, rat for NUFIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NUFIP1 (NM_012345)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUFIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUFIP1
    Sirion Biotech Customized lentivirus for stable overexpression of NUFIP1 
                         Customized lentivirus expression plasmids for stable overexpression of NUFIP1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NUFIP1
    Search LifeMap BioReagents cell lines for NUFIP1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUFIP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NUFIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/38 Interacting proteins for NUFIP1 (Q9UHK02, 3 ENSP000003684594) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TAF9Q165943, ENSP000003702014I2D: score=1 STRING: ENSP00000370201
    YWHAZP631042, 3, ENSP000003095034MINT-3319708 I2D: score=1 STRING: ENSP00000309503
    BRCA1P383983, ENSP000003502834I2D: score=3 STRING: ENSP00000350283
    CCNT1O605633, ENSP000002619004I2D: score=3 STRING: ENSP00000261900
    AK6Q165943I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000492box C/D snoRNP assembly IMP17636026
    GO:0006396RNA processing TAS10556305
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IMP15107825

    NUFIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUFIP1 (NUFP1)

    Search CenterWatch for drugs/clinical trials and news about NUFIP1 / NUFP1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUFIP1 gene: 
    NM_012345.2  

    Unigene Cluster for NUFIP1:

    Nuclear fragile X mental retardation protein interacting protein 1
    Hs.525006  [show with all ESTs]
    Unigene Representative Sequence: NM_012345
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000379161(uc001uzp.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUFIP1
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate NUFIP1 (see all 10):
    hsa-miR-4254 hsa-miR-448 hsa-miR-548e hsa-miR-548v hsa-miR-545 hsa-miR-4275 hsa-miR-153 hsa-miR-548a-3p
    SwitchGear 3'UTR luciferase reporter plasmidNUFIP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NUFIP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUFIP1
    Clone
    Products:
         
    OriGene clones in human, mouse for NUFIP1 (see all 7)
    OriGene ORF clones in mouse, rat for NUFIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NUFIP1 (NM_012345)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUFIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUFIP1
    Sirion Biotech Customized lentivirus for stable overexpression of NUFIP1 
                         Customized lentivirus expression plasmids for stable overexpression of NUFIP1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for NUFIP1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NUFIP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUFIP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUFIP1

    Additional mRNA sequence: 

    AF159548.1 AK314242.1 BC001436.1 BC017745.1 

    4 DOTS entries:

    DT.311423  DT.95265455  DT.121310919  DT.99993491 

    24/78 AceView cDNA sequences (see all 78):

    BC017745 AA313568 AI493868 AI168720 AI445539 AW293648 AA300673 CD557235 
    BX283859 BG188808 AI216506 BM722745 BX374594 CA424844 CB306417 AW297501 
    AI220307 AA377043 AA300838 AA732677 AI470636 AA214642 BG771372 BI835649 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUFIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NUFIP1 Expression
    About this image


    See NUFIP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUFIP1

    SOURCE GeneReport for Unigene cluster: Hs.525006

    UniProtKB/Swiss-Prot: NUFP1_HUMAN, Q9UHK0
    Tissue specificity: Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood
    leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas

        SABiosciences Custom PCR Arrays for NUFIP1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for NUFIP1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NUFIP1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUFIP1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUFIP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUFIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NUFIP1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nufip11 , 5 nuclear fragile X mental retardation protein interacting more1, 5 79.99(n)1
    72.88(a)1
      14 (40.35 cM)5
    272751  NM_013745.51  NP_038773.11 
     761108915 
    chicken
    (Gallus gallus)
    Aves NUFIP11 nuclear fragile X mental retardation protein interacting more 58.9(n)
    51.23(a)
      418841  NM_001030825.1  NP_001025996.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUFIP16
    Uncharacterized protein
    36(a)
    1 ↔ 1
    GL343395.1(591871-615633)
    African clawed frog
    (Xenopus laevis)
    Amphibia AW645513.12   -- 78.78(n)    AW645513.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1714761 zgc:171476 51.33(n)
    45.71(a)
      334271  NM_001114886.1  NP_001108358.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nufip6
    Nufip
    20(a)
    1 ↔ 1
    3L(18739711-18741467)


    ENSEMBL Gene Tree for NUFIP1 (if available)
    TreeFam Gene Tree for NUFIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUFIP1 gene

    NUFIP1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NUFIP1
    PGOHUM00000243235


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/997 SNPs in NUFIP1 are shown (see all 997)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs790489841,2
    C--26315873(+) AAGCC-/TTATAA 2 -- ut310--------
    rs11753861,2
    C,F,H--26457815(+) AGCACA/CCCAGA 1 -- ds50017Minor allele frequency- C:0.02NS NA WA 626
    rs1831948671,2
    --26457847(+) AGAAAG/TCAATC 1 -- ds50010--------
    rs1458931251,2
    --26457918(+) CCAGGG/TATTAA 1 -- ds50010--------
    rs1387756851,2
    --26457939(+) AAATCA/GTATCT 1 -- ds50010--------
    rs1855186491,2
    --26458068(+) GTAATC/TACTAA 1 -- ds50010--------
    rs2001956431,2
    C--26458134(+) AAAAAA/TAACAA 1 -- ds50010--------
    rs1903093671,2
    --26458217(+) GTCCAA/CATGTT 1 -- ut310--------
    rs1821694731,2
    --26458337(+) TAAAAA/GGCACA 1 -- ut310--------
    rs575859571,2
    C,F--26458363(+) TGTAAT/AGCTTA 1 -- ut311Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for NUFIP1 (45513384 - 45563618 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NUFIP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv524788CNV Loss19592680
    dgv1578n71CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NUFIP1
    DNA2.0 Custom Variant and Variant Library Synthesis for NUFIP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604354    OMIM disorders: --

    5 diseases for NUFIP1:    About MalaCards
    mental retardation    intellectual disability    microcephaly    neuronitis
    prostatitis


    NUFIP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NUFIP1
    Human Genome Epidemiology (HuGE) Navigator: NUFIP1 (1 document)

    Export disorders for NUFIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUFIP1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with NUFIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein. (PubMed id 10556305)1, 2, 3 Bardoni B.... Mandel J.-L. (1999)
    2. Human Variation in Alcohol Response Is Influenced by Variation in Neuronal Signaling Genes. (PubMed id 20201926)1, 4 Joslyn G....White R.L. (2010)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Assignment of NUFIP1 (nuclear FMRP interacting protein 1) gene to chromosome 13q14 and assignment of a pseudogene to chromosome 6q12. (PubMed id 10894927)1, 3 Bardoni B....Mandel J.L. (2000)
    7. Genome-wide association study identifies novel loci as sociated with concentrations of four plasma phospholipid fatty acids in the de n ovo lipogenesis pathway: results from the Cohorts for Heart and Aging Research i n Genomic Epidemiology (CHARGE) consortium. (PubMed id 23362303)1 Wu J.H....Mozaffarian D. (2013)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26747 HGNC: 8057 AceView: NUFIP1 Ensembl:ENSG00000083635 euGenes: HUgn26747
    ECgene: NUFIP1 H-InvDB: NUFIP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUFIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUFIP1 gene:
    Search GeneIP for patents involving NUFIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NUFIP1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for NUFIP1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for NUFIP1  
     OriGene qSTAR qPCR primer pairs in human, mouse for NUFIP1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for NUFIP1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NUFIP1   OriGene Custom Protein Services for NUFIP1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NUFIP1
     QIAGEN SeqTarget long-range PCR primers for resequencing NUFIP1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUFIP1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUFIP1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUFIP1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUFIP1
     GenScript Custom Purified and Recombinant Proteins Services for NUFIP1 GenScript cDNA clones with any tag delivered in your preferred vector for NUFIP1
     GenScript Custom Assay Services for NUFIP1 GenScript Custom Superior Antibodies Services for NUFIP1
     GenScript Custom overexpressing Cell Line Services for NUFIP1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NUFIP1 promoter
     Search Chromatin IP Primers for NUFIP1
     RT2 qPCR Primer Assay in human, mouse, rat NUFIP1
     GNC Network for NUFIP1
     SABiosciences Custom PCR Arrays for NUFIP1
     Search Tocris compounds for NUFIP1 (NUFP1)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NUFIP1 antibodies
     NUFIP1 proteins
     NUFIP1 lysates
     Antibodies for NUFIP1
     See all of Abcam's Antibodies, Kits and Proteins for NUFIP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for NUFIP1
     Antibodies for NUFIP1
     ELISAs for NUFIP1
     CLIAs for NUFIP1
     Search LifeMap BioReagents cell lines for NUFIP1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUFIP1
     SwitchGear 3'UTR luciferase reporter plasmids for NUFIP1
     SwitchGear Promoter luciferase reporter plasmids for NUFIP1
     ThermoFisher Antibodies for NUFIP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUFIP1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for NUFIP1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NUFIP1
    Customized:
     lentivirus for stable overexpression of NUFIP1
     lentivirus expression plasmids for stable overexpression of NUFIP1
     adenovirus for overexpression of NUFIP1
     LSBio Antibodies in human, mouse, rat for NUFIP1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NUFIP1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4