Aliases for NUDT9 Gene
External Ids for NUDT9 Gene
Previous GeneCards Identifiers for NUDT9 Gene
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NUDT9 Gene
NUDT9 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 9) is a Protein Coding gene. Among its related pathways are Metabolism and Purine metabolism (REACTOME). GO annotations related to this gene include ADP-sugar diphosphatase activity and adenosine-diphosphatase activity.
UniProtKB/Swiss-Prot for NUDT9 Gene
Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5-phosphate