Aliases for NUDT9 Gene
External Ids for NUDT9 Gene
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for NUDT9 Gene
NUDT9 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 9) is a Protein Coding gene. Among its related pathways are Metabolism and Purine metabolism (REACTOME). GO annotations related to this gene include ADP-sugar diphosphatase activity and adenosine-diphosphatase activity.
UniProtKB/Swiss-Prot for NUDT9 Gene
Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5-phosphate