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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUDT9 Gene

protein-coding   GIFtS: 54
GCID: GC04P088343

Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif...

  Search for NUDT9
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 91 2     ADP-Ribose Pyrophosphatase, Mitochondrial2
Adenosine Diphosphoribose Pyrophosphatase2 3     ADP-Ribose Pyrosphosphatase NUDT92
ADPR-PPase2 3     Nucleoside Diphosphate Linked Moiety X-Type Motif 92
NUDT102 3     EC 3.6.1.133
ADP-Ribose Diphosphatase2 3     Nucleoside Diphosphate-Linked Moiety X Motif 93
ADP-Ribose Phosphohydrolase2 3     Nudix Motif 93

External Ids:    HGNC: 80561   Entrez Gene: 533432   Ensembl: ENSG000001705027   OMIM: 6060225   UniProtKB: Q9BW913   

Export aliases for NUDT9 gene to outside databases

Previous GC identifers: GC04P088501 GC04P088645 GC04P088802 GC04P088700 GC04P084089


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUDT9 Gene:
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of
diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose
pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal
ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for NUDT9 Gene: 
NUDT9 (nudix (nucleoside diphosphate linked moiety X)-type motif 9) is a protein-coding gene. Among its related super-pathways are Purine metabolism and Metabolic pathways. GO annotations related to this gene include adenosine-diphosphatase activity and ADP-ribose diphosphatase activity.

UniProtKB/Swiss-Prot: NUDT9_HUMAN, Q9BW91
Function: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate

Gene Wiki entry for NUDT9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUDT9 gene promoter:
         Nkx3-1   Nkx3-1 v4   ISGF-3   Nkx3-1 v1   CREB   Nkx3-1 v2   deltaCREB   COMP1   Nkx3-1 v3   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUDT9 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUDT9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDT9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q22.1   Ensembl cytogenetic band:  4q22.1   HGNC cytogenetic band: 4q22.1

NUDT9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT9 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P088343:  view genomic region     (about GC identifiers)

Start:
88,343,734 bp from pter      End:
88,380,606 bp from pter
Size:
36,873 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUDT9_HUMAN, Q9BW91 (See protein sequence)
Recommended Name: ADP-ribose pyrophosphatase, mitochondrial precursor  
Size: 350 amino acids; 39125 Da
Cofactor: Magnesium
Cofactor: Manganese
Subunit: Monomer. Interacts with GLOD4
Subcellular location: Isoform 1: Mitochondrion
2 PDB 3D structures from and Proteopedia for NUDT9:
1Q33 (3D)        1QVJ (3D)    
Secondary accessions: Q8NBN1 Q8NCB9 Q8NG25
Alternative splicing: 2 isoforms:  Q9BW91-1   Q9BW91-2   

Explore the universe of human proteins at neXtProt for NUDT9: NX_Q9BW91

Explore proteomics data for NUDT9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BW91

  • NUDT9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUDT9 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001234940.1  NP_076952.1  NP_932155.1  

    ENSEMBL proteins: 
     ENSP00000303575   ENSP00000424702   ENSP00000421811   ENSP00000410270   ENSP00000422232  
    Reactome Protein details: Q9BW91
    Human Recombinant Protein Products for NUDT9: 
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    Cloud-Clone Corp. Proteins for NUDT9 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular NAS11385575
    GO:0005739mitochondrion ----
    GO:0005759mitochondrial matrix TAS--

    NUDT9 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NUDT: Nudix motif containing

    2 InterPro protein domains:
     IPR015797 NUDIX_hydrolase_dom-like
     IPR000086 NUDIX_hydrolase_dom

    Graphical View of Domain Structure for InterPro Entry Q9BW91

    ProtoNet protein and cluster: Q9BW91

    1 Blocks protein domain: IPB000086 NUDIX hydrolase

    UniProtKB/Swiss-Prot: NUDT9_HUMAN, Q9BW91
    Similarity: Belongs to the Nudix hydrolase family. NudF subfamily
    Similarity: Contains 1 nudix hydrolase domain


    NUDT9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUDT9_HUMAN, Q9BW91
    Function: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate
    Catalytic activity: ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate
    Induction: Isoform 1 is inhibited by fluoride and N-acetyl-p-benzoquinoneimine

         Enzyme Number (IUBMB): EC 3.6.1.131

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity ----
    GO:0019144ADP-sugar diphosphatase activity NAS11385575
    GO:0043262adenosine-diphosphatase activity IEA--
    GO:0047631ADP-ribose diphosphatase activity EXP--
         
    NUDT9 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Nudt9 (no phenotypes)

    NUDT9 for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUDT9 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Purine metabolism
    Metabolism of nucleotides0.42
    2Metabolism
    Metabolism0.40
    3Purine metabolism
    Purine metabolism0.38
    4Phosphate bond hydrolysis by NUDT proteins
    Phosphate bond hydrolysis by NUDT proteins

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for NUDT9
        Metabolism of nucleotides
    Metabolism
    Phosphate bond hydrolysis by NUDT proteins


    1         Kegg Pathway  (Kegg details for NUDT9):
        Purine metabolism


    NUDT9 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUDT9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/10 Interacting proteins for NUDT9 (Q9BW913 ENSP000003035754) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDM2Q009873I2D: score=1 
    PGM1ENSP000003601254STRING: ENSP00000360125
    PGM2ENSP000003713934STRING: ENSP00000371393
    PRPS2ENSP000003815044STRING: ENSP00000381504
    ADPRMENSP000003690994STRING: ENSP00000369099
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034656nucleobase-containing small molecule catabolic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046032ADP catabolic process IEA--
    GO:0046709IDP catabolic process IEA--
    GO:0055086nucleobase-containing small molecule metabolic process TAS--

    NUDT9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NUDT9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for NUDT9

    4 HMDB Compounds for NUDT9    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine diphosphate ribose(Rib5)ppA (see all 13)20762-30-5--
    MagnesiumMagnesium (see all 2)7439-95-4--
    Manganesemanganese 7439-96-5--

    2 DrugBank Compounds for NUDT9    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Beta-D-Glucose-- 50-99-7target--17139284 17016423
    [(2r,3s,4s,5r)-3,4,5-Trihydroxytetrahydrofuran-2-Yl]Methyl Dihydrogen Phosphate-- --target--17139284 17016423

    1 Novoseek inferred chemical compound relationship for NUDT9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adpribose 84.9 7 16860484 (2), 12427752 (1), 18073331 (1), 17166279 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about NUDT9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUDT9 gene (3 alternative transcripts): 
    NM_001248011.1  NM_024047.4  NM_198038.2  

    Unigene Cluster for NUDT9:

    Nudix (nucleoside diphosphate linked moiety X)-type motif 9
    Hs.149500  [show with all ESTs]
    Unigene Representative Sequence: NM_024047
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302174 ENST00000512216 ENST00000514345 ENST00000473942(uc003hqq.3 uc010ikl.3 uc003hqr.3)
    ENST00000514227 ENST00000440591 ENST00000502933 ENST00000515371
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    Additional mRNA sequence: 

    AF265341.1 AF273028.1 AK027295.1 AK074845.1 AK075408.1 AK308028.1 AY026252.1 AY359123.1 
    BC000542.2 

    13 DOTS entries:

    DT.315308  DT.92045022  DT.100841614  DT.100027645  DT.100819331  DT.92426610  DT.100027640  DT.315309 
    DT.100819324  DT.121234885  DT.92426611  DT.95170258  DT.121234852 

    24/240 AceView cDNA sequences (see all 240):

    BU509081 AK027295 AI473395 BE893740 CD243190 BE463403 CR619203 BM981911 
    BM665071 CF995057 BQ267468 BM716433 BF739849 CA394691 BQ270037 CF995247 
    CR604538 BC000542 BQ083825 NM_024047 BM769907 NM_198039 BQ448676 BQ286697 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for NUDT9 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12
    SP1:                                            -                                   -     -                                       
    SP2:                          -     -     -     -                                   -     -                                       
    SP3:                    -     -     -     -     -                                   -     -                                       
    SP4:                                                                                                                              
    SP5:                                                                                                                              


    ECgene alternative splicing isoforms for NUDT9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUDT9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTAAATTA
    NUDT9 Expression
    About this image


    See NUDT9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUDT9

    SOURCE GeneReport for Unigene cluster: Hs.149500

    UniProtKB/Swiss-Prot: NUDT9_HUMAN, Q9BW91
    Tissue specificity: Ubiquitously expressed but isoform 1 is the most predominant isoform

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NUDT9 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nudt91 , 5 nudix (nucleoside diphosphate linked moiety X)-type more1, 5 82.86(n)1
    89.43(a)1
      5 (50.54 cM)5
    741671  NM_028794.31  NP_083070.21 
     1040463065 
    chicken
    (Gallus gallus)
    Aves NUDT91 nudix (nucleoside diphosphate linked moiety X)-type more 70.03(n)
    70.89(a)
      422587  XM_420546.3  XP_420546.3 
    lizard
    (Anolis carolinensis)
    Reptilia NUDT96
    Uncharacterized protein
    66(a)
    1 ↔ 1
    5(831754-846415)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.34442 Xenopus laevis transcribed sequence with weak similarity more 74.76(n)    CD302577.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufu33g072 Danio rerio cDNA clone MGC63924 IMAGE6790829, complete more 78.06(n)    BC057417.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG182173
    CG40981
    CG40981 53(a)
    (best of 2)3
    53.41(n)1
    53.53(a)1
      73B13
    398541  NM_145191.11  NP_660192.11 
    worm
    (Caenorhabditis elegans)
    Secernentea ndx-61 Protein NDX-6 56.05(n)
    52.42(a)
      173916  NM_062614.2  NP_495015.1 


    ENSEMBL Gene Tree for NUDT9 (if available)
    TreeFam Gene Tree for NUDT9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUDT9 gene
    1 SIMAP similar gene for NUDT9 using alignment to 4 protein entries:     NUDT9_HUMAN (see all proteins):
    TRPM2

    NUDT9 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NUDT9
    PGOHUM00000238579


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/818 SNPs in NUDT9 are shown (see all 818)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2012124541,2
    C--84092597(-) AAATTC/TTTTTT 3 -- int10--------
    rs1883311501,2
    --88150033(+) GTGCCA/GAGAAA 2 -- us2k10--------
    rs1511988701,2
    --88150047(+) ACTTTC/TATATG 3 -- us2k10--------
    rs68442061,2
    C,F,H--88150131(+) cacttT/Cgttat 3 -- us2k18Minor allele frequency- C:0.04NS EA NA WA CSA 542
    rs1409669201,2
    --88150144(+) ATTCAC/TCTCTT 3 -- us2k10--------
    rs1156888431,2
    C,F--88150218(+) TAACTC/TGCACC 3 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1150379251,2
    F--88150239(+) ACGTAT/CAGCCA 3 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1810414281,2
    --88150292(+) AACTTG/TGTATC 3 -- us2k10--------
    rs800538171,2
    F--88150315(+) GTCCCC/TTTTTT 3 -- us2k11Minor allele frequency- T:0.02WA 118
    rs119352261,2
    C,F,A,H--88150439(+) tctatC/Ttcgtg 3 -- us2k112Minor allele frequency- T:0.16NS EA NA WA CSA 543

    HapMap Linkage Disequilibrium report for NUDT9 (88343734 - 88380606 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NUDT9: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NUDT9
    DNA2.0 Custom Variant and Variant Library Synthesis for NUDT9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NUDT9 for disorders           About MalaCards
    OMIM gene information: 606022    OMIM disorders: --


    NUDT9 for disorders           About GeneDecksing


    Export disorders for NUDT9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUDT9 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with NUDT9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase. (PubMed id 12427752)1, 2, 3, 9 Perraud A.-L.... Scharenberg A.M. (2003)
    2. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. (PubMed id 11385575)1, 2, 3 Perraud A.-L....Scharenberg A.M. (2001)
    3. Interaction of C17orf25 with ADP-ribose pyrophosphatase NUDT9 detected via yeast two-hybrid method. (PubMed id 12897971)1, 2, 9 Zhang H.-T.... Gong Y. (2003)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The crystal structure and mutational analysis of human NUDT9. (PubMed id 12948489)1, 2 Shen B.W.... Stoddard B.L. (2003)
    8. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    9. Cloning, expression and characterisation of a human Nudix hydrolase specific for adenosine 5'-diphosphoribose (ADP-ribose). (PubMed id 11825615)1, 2 Lin S.... McLennan A.G. (2002)
    10. Differential expression of NUDT9 at different phases of the menstrual cycle and in different components of normal and neoplastic hum an endometrium. (PubMed id 19574167)1, 9 Chen L.Y....Chen M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53343 HGNC: 8056 AceView: NUDT9 Ensembl:ENSG00000170502 euGenes: HUgn53343
    ECgene: NUDT9 Kegg: 53343 H-InvDB: NUDT9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUDT9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUDT9 gene:
    Search GeneIP for patents involving NUDT9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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