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NUDT8 Gene

protein-coding   GIFtS: 48
GCID: GC11M067395

Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 81 2
Nudix Motif 82 3
Nucleoside Diphosphate-Linked Moiety X Motif 8, Mitochondrial2
EC 3.6.1.-3

External Ids:    HGNC: 80551   Entrez Gene: 2545522   Ensembl: ENSG000001677997   UniProtKB: Q8WV743   

Export aliases for NUDT8 gene to outside databases

Previous GC identifers: GC11U990247 GC11M067645 GC11M067170 GC11M067151 GC11M063724


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NUDT8 Gene:
NUDT8 (nudix (nucleoside diphosphate linked moiety X)-type motif 8) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is NUDT7.

UniProtKB/Swiss-Prot: NUDT8_HUMAN, Q8WV74
Function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NUDT8 gene promoter:
         E47   Meis-1b   GATA-1   CREB   HEN1   PPAR-gamma1   COMP1   Meis-1a   PPAR-gamma2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUDT8 promoter sequence
   Search Chromatin IP Primers for NUDT8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NUDT8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.2   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.2

NUDT8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT8 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M067395:  view genomic region     (about GC identifiers)

Start:
67,395,409 bp from pter      End:
67,397,401 bp from pter
Size:
1,993 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NUDT8_HUMAN, Q8WV74 (See protein sequence)
Recommended Name: Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor  
Size: 236 amino acids; 25370 Da
Cofactor: Magnesium or manganese (By similarity)
Secondary accessions: Q6ZW59
Alternative splicing: 2 isoforms:  Q8WV74-1   Q8WV74-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUDT8: NX_Q8WV74

Explore proteomics data for NUDT8 at MOPED


See NUDT8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001230679.1  NP_862826.1  

ENSEMBL proteins: 
 ENSP00000301490   ENSP00000365883  

NUDT8 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
NUDT: Nudix motif containing

2 InterPro protein domains:
 IPR015797 NUDIX_hydrolase_dom-like
 IPR000086 NUDIX_hydrolase_dom

Graphical View of Domain Structure for InterPro Entry Q8WV74

ProtoNet protein and cluster: Q8WV74

1 Blocks protein domain: IPB000086 NUDIX hydrolase

UniProtKB/Swiss-Prot: NUDT8_HUMAN, Q8WV74
Similarity: Belongs to the Nudix hydrolase family
Similarity: Contains 1 nudix hydrolase domain


Find genes that share domains with NUDT8           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: NUDT8_HUMAN, Q8WV74
Function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity)

     Enzyme Number (IUBMB): EC 3.6.1.-1

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016787hydrolase activity IEA--
GO:0046872metal ion binding IEA--
     
Find genes that share ontologies with NUDT8           About GenesLikeMe


Phenotypes:
     6 GenomeRNAi human phenotypes for NUDT8:
 Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased nuclei size in G2M 
 G0/1 arrest  Increased G1 DNA content 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NUDT8
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NUDT8
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NUDT8

miRNA
Products:
    
miRTarBase miRNAs that target NUDT8:
hsa-let-7e-5p (MIRT051612)

Block miRNA regulation of human, mouse, rat NUDT8 using miScript Target Protectors
8 qRT-PCR Assays for microRNAs that regulate NUDT8:
hsa-miR-588 hsa-miR-7 hsa-miR-646 hsa-miR-103a hsa-miR-298 hsa-miR-1286 hsa-miR-107 hsa-miR-1910
SwitchGear 3'UTR luciferase reporter plasmidNUDT8 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for NUDT8
Predesigned siRNA for gene silencing in human, mouse, rat NUDT8

Gene Editing
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GenScript: all cDNA clones in your preferred vector: NUDT8 (NM_181843)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDT8

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT8


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
NUDT8_HUMAN, Q8WV74: Mitochondrion (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion2
cytosol1
extracellular1
golgi apparatus1
nucleus1
plasma membrane1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IEA--

Find genes that share ontologies with NUDT8           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NUDT8
Interactions:

    Search GeneGlobe Interaction Network for NUDT8

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

Selected Interacting proteins for NUDT8 (ENSP000003014904) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
InteractantInteraction Details
GeneCardExternal ID(s)
PMPCBENSP000002492694STRING: ENSP00000249269
PMPCAENSP000003607824STRING: ENSP00000360782
UQCRC1ENSP000002034074STRING: ENSP00000203407
GNPDA1ENSP000003118764STRING: ENSP00000311876
GNPDA2ENSP000002954484STRING: ENSP00000295448
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NUDT8

6 HMDB Compounds for NUDT8    About this table
CompoundSynonyms CAS #PubMed Ids
ADPadenosindiphosphorsaeure (see all 8)58-64-0--
CDPCDP (see all 3)63-38-7--
Guanosine diphosphate5'-GDP (see all 10)146-91-8--
MagnesiumMagnesium (see all 2)7439-95-4--
Manganesemanganese 7439-96-5--
dTDPDeoxy-tdp (see all 5)491-97-4--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for NUDT8 gene (2 alternative transcripts): 
NM_001243750.1  NM_181843.2  

Unigene Cluster for NUDT8:

Nudix (nucleoside diphosphate linked moiety X)-type motif 8
Hs.433329  [show with all ESTs]
Unigene Representative Sequence: BE903195
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000301490(uc001omn.3 uc001omo.2) ENST00000376693 ENST00000534054

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat NUDT8 using miScript Target Protectors
8 qRT-PCR Assays for microRNAs that regulate NUDT8:
hsa-miR-588 hsa-miR-7 hsa-miR-646 hsa-miR-103a hsa-miR-298 hsa-miR-1286 hsa-miR-107 hsa-miR-1910
SwitchGear 3'UTR luciferase reporter plasmidNUDT8 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for NUDT8
Predesigned siRNA for gene silencing in human, mouse, rat NUDT8
Clone
Products:
     
OriGene clones in human, mouse for NUDT8 (see all 6)
OriGene ORF clones in mouse, rat for NUDT8
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NUDT8 (NM_181843)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUDT8
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDT8
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for NUDT8
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NUDT8
  QuantiTect SYBR Green Assays in human, mouse, rat NUDT8
  QuantiFast Probe-based Assays in human, mouse, rat NUDT8

Additional mRNA sequence: 

AK123561.1 BC018644.1 

4 DOTS entries:

DT.100759756  DT.95362522  DT.92417400  DT.91704880 

Selected AceView cDNA sequences (see all 32):

CB140633 AK123561 BM986919 CR619375 BU739108 NM_181843 BX348477 BM461896 
BE878078 AI659740 AL558598 AI743601 CA433544 CA431033 BI862024 AI857666 
BI820659 BC018644 AW003775 BX376895 BE903195 BF685144 AF150120 BM717290 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for NUDT8    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1:              -                     
SP2:              -                     
SP3:                                    


ECgene alternative splicing isoforms for NUDT8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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NUDT8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GACCACACCG
NUDT8 Expression
About this image


NUDT8 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 6) fully expand
 
 Brain (Nervous System)    fully expand to see all 2 entries
         Cerebral Cortex
 
 Ovary (Reproductive System)
         Oviduct
 
 Pancreas (Endocrine System)
         Islets of Langerhans
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Liver (Hepatobiliary System)
         Hepatocytes Liver Lobule
NUDT8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NUDT8 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.433329
    Custom PCR Arrays for NUDT8
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT8

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for NUDT8 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Nudt81 , 5 nudix (nucleoside diphosphate linked moiety X)-type more1, 5 81.94(n)1
83.25(a)1
  19 (3.71 cM)5
663871  NM_025529.31  NP_079805.11 
 40005805 
chicken
(Gallus gallus)
Aves NUDT81 nudix (nucleoside diphosphate linked moiety X)-type more 65.42(n)
60.45(a)
  101748150  XM_004941283.1  XP_004941340.1 
lizard
(Anolis carolinensis)
Reptilia NUDT86
nudix (nucleoside diphosphate linked moiety X)-typ...
50(a)
1 ↔ 1
1(90628307-90635473)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1004875181 uncharacterized LOC100487518 52.08(n)
50(a)
  100487518  XM_002938497.2  XP_002938543.2 
zebrafish
(Danio rerio)
Actinopterygii nudt81 nudix (nucleoside diphosphate linked moiety X)-type more 57.73(n)
55.67(a)
  791929  NM_001077316.1  NP_001070784.1 
fruit fly
(Drosophila melanogaster)
Insecta CG110951 CG11095 50.59(n)
40(a)
  32348  NM_132699.3  NP_572927.1 
worm
(Caenorhabditis elegans)
Secernentea ndx-31 ndx-3 45.57(n)
40.11(a)
  173857  NM_062511.3  NP_494912.2 


ENSEMBL Gene Tree for NUDT8 (if available)
TreeFam Gene Tree for NUDT8 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for NUDT8 gene
NUDT72  

Find genes that share paralogs with NUDT8           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for NUDT8 (see all 81)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1466123381,2
--67394910(+) CACCCC/TCTCTG 2 -- int1 ds50010--------
rs1138183631,2
C--67395004(+) CTGCAT/-GTAAC 2 -- int1 ds50011Minor allele frequency- -:0.50CSA 2
rs767988431,2
C,F--67395015(+) ACCCAG/AGGGCA 2 -- int1 ds50011Minor allele frequency- A:0.02NA 120
rs1826610491,2
--67395125(+) AGTGCC/TTAAGA 2 -- int1 ds50010--------
rs1160921871,2
F--67395238(+) TGTTGG/ACCCTG 2 -- int1 ds50011Minor allele frequency- A:0.02WA 118
rs1410236951,2
--67395355(+) CAGCGA/TCCTGG 2 -- int1 ds50010--------
rs1180327211,2
C,F--67395456(+) GCCTGA/TCAGGG 3 * C ut31 stg11Minor allele frequency- T:0.08EA 120
rs1877409281,2
--67395518(+) CAGGCC/TGGCCA 3 S G ut31 mis10--------
rs3679901561,2
C--67395526(+) CCAGGC/TGGGGC 3 H R ut31 mis10--------
rs1502727481,2
C--67395527(+) CAGGCG/AGGGCT 3 /R /C ut31 mis11Minor allele frequency- A:0.00EU 535

HapMap Linkage Disequilibrium report for NUDT8 (67395409 - 67397401 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for NUDT8 (see all 12):    About this table    
Variant IDTypeSubtypePubMed ID
esv2422195CNV Duplication17116639
dgv1197n71CNV Loss21882294
nsv469963CNV Loss18288195
dgv154n27CNV Loss19166990
dgv1194n71CNV Loss21882294
dgv1198n71CNV Loss21882294
nsv897801CNV Loss21882294
nsv897815CNV Loss21882294
nsv468609CNV Loss19166990
dgv1196n71CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing NUDT8
DNA2.0 Custom Variant and Variant Library Synthesis for NUDT8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Find genes that share disorders with NUDT8           About GenesLikeMe

Genetic Association Database (GAD): NUDT8
Human Genome Epidemiology (HuGE) Navigator: NUDT8 (1 document)

Export disorders for NUDT8 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for NUDT8 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NUDT8)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives. (PubMed id 11415433)1, 3 Gasmi L. and McLennan A.G. (Biochem. J. 2001)
  5. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
  6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 254552 HGNC: 8055 AceView: NUDT8 Ensembl:ENSG00000167799 euGenes: HUgn254552
ECgene: NUDT8 H-InvDB: NUDT8

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for NUDT8 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for NUDT8 gene:
Search GeneIP for patents involving NUDT8

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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