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NUDT7 Gene

protein-coding   GIFtS: 52
GCID: GC16P077756

Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 71 2
Peroxisomal Coenzyme A Diphosphatase NUDT72
EC 3.6.1.-3
Nucleoside Diphosphate-Linked Moiety X Motif 73
Nudix Motif 73

External Ids:    HGNC: 80541   Entrez Gene: 2839272   Ensembl: ENSG000001408767   OMIM: 6092315   UniProtKB: P0C0243   

Export aliases for NUDT7 gene to outside databases

Previous GC identifers: GC16U990126 GC16P077495 GC16P076316 GC16P063512


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NUDT7 Gene:
The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially
toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different
nucleotide substrates, cofactors, and signaling molecules. Alternatively spliced transcript variants encoding
multiple isoforms have been found for this gene. (provided by RefSeq, Aug 2011)

GeneCards Summary for NUDT7 Gene:
NUDT7 (nudix (nucleoside diphosphate linked moiety X)-type motif 7) is a protein-coding gene. GO annotations related to this gene include manganese ion binding and receptor binding. An important paralog of this gene is NUDT8.

UniProtKB/Swiss-Prot: NUDT7_HUMAN, P0C024
Function: Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar
efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into
3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside
5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or
thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or
regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8
snoRNA decapping activity. Binds U8 snoRNA (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the NUDT7 gene promoter:
         Pbx1a   ATF-2   Lmo2   LCR-F1   GATA-1   MEF-2A   POU2F1   Nkx6-1   POU2F1a   SEF-1 (1)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NUDT7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NUDT7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.1   Ensembl cytogenetic band:  16q23.1   HGNC cytogenetic band: 16q23.1

NUDT7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT7 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P077756:  view genomic region     (about GC identifiers)

Start:
77,756,411 bp from pter      End:
77,776,157 bp from pter
Size:
19,747 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NUDT7_HUMAN, P0C024 (See protein sequence)
Recommended Name: Peroxisomal coenzyme A diphosphatase NUDT7  
Size: 238 amino acids; 26942 Da
Cofactor: Manganese or magnesium (By similarity)
Secondary accessions: B4DLE5 H3BUB8
Alternative splicing: 3 isoforms:  P0C024-1   P0C024-2   P0C024-3   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for NUDT7: NX_P0C024

Explore proteomics data for NUDT7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NUDT7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001099133.1  NP_001230586.1  NP_001230589.1  NP_001230590.1  

    ENSEMBL proteins: 
     ENSP00000457566   ENSP00000268533   ENSP00000456363   ENSP00000387707   ENSP00000454617  

    NUDT7 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    NUDT: Nudix motif containing

    3 InterPro protein domains:
     IPR015797 NUDIX_hydrolase_dom-like
     IPR000059 NUDIX_hydrolase_NudL_CS
     IPR000086 NUDIX_hydrolase_dom

    Graphical View of Domain Structure for InterPro Entry P0C024

    ProtoNet protein and cluster: P0C024

    1 Blocks protein domain: IPB000086 NUDIX hydrolase

    UniProtKB/Swiss-Prot: NUDT7_HUMAN, P0C024
    Similarity: Belongs to the Nudix hydrolase family. PCD1 subfamily
    Similarity: Contains 1 nudix hydrolase domain


    Find genes that share domains with NUDT7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUDT7_HUMAN, P0C024
    Function: Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar
    efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into
    3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside
    5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or
    thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or
    regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8
    snoRNA decapping activity. Binds U8 snoRNA (By similarity)
    Enzyme regulation: Inhibited by fluoride (By similarity)

         Enzyme Number (IUBMB): EC 3.6.1.-1

         Gene Ontology (GO): Selected molecular function terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0003674molecular_function ND--
    GO:0003986acetyl-CoA hydrolase activity ISS--
    GO:0005102receptor binding IPI--
    GO:0016787hydrolase activity ----
         
    Find genes that share ontologies with NUDT7           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NUDT7

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NUDT7_HUMAN, P0C024: Peroxisome (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    peroxisome4
    cytosol1
    endoplasmic reticulum1
    extracellular1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005777peroxisome ISS--

    Find genes that share ontologies with NUDT7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NUDT7 About    
    See pathways by source

    SuperPathContained pathways About
    1Peroxisome
    Peroxisome


    Find genes that share SuperPaths with NUDT7           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for NUDT7):
        Peroxisome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NUDT7
    Interactions:

        Search GeneGlobe Interaction Network for NUDT7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for NUDT7 (ENSP000002685334) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GSTA4ENSP000003599984STRING: ENSP00000359998
    PMPCBENSP000002492694STRING: ENSP00000249269
    UQCRC1ENSP000002034074STRING: ENSP00000203407
    GNPDA1ENSP000003118764STRING: ENSP00000311876
    GNPDA2ENSP000002954484STRING: ENSP00000295448
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0009132nucleoside diphosphate metabolic process IEA--
    GO:0015938coenzyme A catabolic process ISS--
    GO:0046356acetyl-CoA catabolic process ISS--
    GO:0050873brown fat cell differentiation IEA--

    Find genes that share ontologies with NUDT7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for NUDT7

    Selected HMDB Compounds for NUDT7 (see all 38)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NUDT7 gene (4 alternative transcripts): 
    NM_001105663.2  NM_001243657.1  NM_001243660.1  NM_001243661.1  

    Unigene Cluster for NUDT7:

    Nudix (nucleoside diphosphate linked moiety X)-type motif 7
    Hs.282665  [show with all ESTs]
    Unigene Representative Sequence: NM_001243657
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000564085(uc002fff.3) ENST00000268533(uc021tlp.1 uc010chd.3 uc021tlq.1 uc010vnj.2)
    ENST00000568787 ENST00000437314 ENST00000563839 ENST00000564031
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    Additional mRNA sequence: 

    AK296963.1 EU981826.1 

    8 DOTS entries:

    DT.120714593  DT.100777681  DT.92420840  DT.208286  DT.120714606  DT.99997694  DT.100777680  DT.91996140 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NUDT7    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
    SP1:                          -                                       
    SP2:                          -           -                           
    SP3:                                -     -                           
    SP4:                          -     -     -                           


    ECgene alternative splicing isoforms for NUDT7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NUDT7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAGCATTA
    NUDT7 Expression
    About this image


    NUDT7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    NUDT7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NUDT7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.282665

    UniProtKB/Swiss-Prot: NUDT7_HUMAN, P0C024
    Tissue specificity: Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta.
    Weakly expressed in brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NUDT7 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nudt71 , 5 nudix (nucleoside diphosphate linked moiety X)-type more1, 5 74.74(n)1
    67.84(a)1
      8 (60.53 cM)5
    675281  NM_024437.31  NP_077757.21 
     1141335575 
    chicken
    (Gallus gallus)
    Aves NUDT71 nudix (nucleoside diphosphate linked moiety X)-type more 56.93(n)
    50(a)
      415800  NM_001252066.2  NP_001238995.2 
    lizard
    (Anolis carolinensis)
    Reptilia NUDT76
    nudix (nucleoside diphosphate linked moiety X)-typ...
    48(a)
    1 ↔ 1
    GL343446.1(8521-12429)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nudt71 nudix (nucleoside diphosphate linked moiety X)-type more 54.67(n)
    48.89(a)
      100379717  XM_004913571.1  XP_004913628.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003294711 peroxisomal coenzyme A diphosphatase NUDT7-like 50.32(n)
    42.72(a)
      100329471  XM_005163212.1  XP_005163269.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ndx-86
    Protein NDX-8 (ndx-8) mRNA, complete cds
    27(a)
    1 ↔ 1
    I(13503045-13507054) WBGene00003585
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons NUDT111 NUDT11 46.44(n)
    36.52(a)
      834634  NM_123962.3  NP_199406.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g02094001 Os05g0209400 46.79(n)
    37.27(a)
      4338090  NM_001061445.1  NP_001054910.1 


    ENSEMBL Gene Tree for NUDT7 (if available)
    TreeFam Gene Tree for NUDT7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NUDT7 gene
    NUDT82  

    Find genes that share paralogs with NUDT7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NUDT7 (see all 745)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3717339961,2
    C--63522381(+) CGTCT-/AAAAAA 4 -- int10--------
    rs770341441,2
    C--77756099(+) CTGTA-/TTTTTT 4 -- us2k10--------
    rs114218661,2
    C--77758332(+) TTTTTT/-CTTTT 4 -- int1 trp31Minor allele frequency- -:0.00CSA 2
    rs1137905131,2
    C,F--77763566(+) AAAAAC/TGCAAA 4 -- int11Minor allele frequency- T:0.50CSA 2
    rs105563571,2
    C--77765239(+) accat-/GG    
       ACCAT
    atata
    4 -- int10--------
    rs612767681,2
    C--77768614(+) AAAAA-/AGGAAG 4 -- int10--------
    rs58180801,2
    C--77776592(+) TGTTGT/-TACAT 4 -- ds50011Minor allele frequency- -:0.00NA 2
    rs121033961,2
    C,F,H--78762060(+) TAAATA/TTCACA 4 -- us2k119Minor allele frequency- T:0.21NS EA NA WA CSA 2330
    rs80602521,2
    C,F--78762067(+) CACAGC/AGATAT 4 -- us2k15Minor allele frequency- A:0.11WA CSA NA EA 362
    rs80605861,2
    C,F,A,H--78762186(+) ttcttC/Tcataa 4 -- us2k1 trp39Minor allele frequency- T:0.32NS EA NA WA 782

    HapMap Linkage Disequilibrium report for NUDT7 (77756411 - 77776157 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for NUDT7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2714736CNV Deletion23290073
    nsv521833CNV Loss19592680
    nsv457542CNV Gain19166990
    nsv457543CNV Gain19166990
    nsv471098CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NUDT7
    DNA2.0 Custom Variant and Variant Library Synthesis for NUDT7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609231    OMIM disorders: --


    Find genes that share disorders with NUDT7           About GenesLikeMe

    Genetic Association Database (GAD): NUDT7
    Human Genome Epidemiology (HuGE) Navigator: NUDT7 (1 document)

    Export disorders for NUDT7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NUDT7 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NUDT7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives. (PubMed id 11415433)1, 2, 3, 9 Gasmi L. and McLennan A.G. (Biochem. J. 2001)
    2. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PubMed id 19844255)1, 4 Dastani Z....Genest J. (Eur. J. Hum. Genet. 2010)
    3. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (Nature 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    6. A proteome-wide perspective on peroxisome targeting signal 1(PTS1)- Pex5p affinities. (PubMed id 20178365)1 Ghosh D. and Berg J.M. (J. Am. Chem. Soc. 2010)
    7. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 283927 HGNC: 8054 Ensembl:ENSG00000140876 euGenes: HUgn283927 ECgene: NUDT7 Kegg: 283927
    H-InvDB: NUDT7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NUDT7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NUDT7 gene:
    Search GeneIP for patents involving NUDT7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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